Clinical trials: Urinary Tract Infection (UTI)
Recurrent Urinary Tract Infections
Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It affects 150 million people annually. Treatment of patients with UTI entails a high consumption of antibiotics and large social and health…
- Trial name
- BIrUTI (NCT04846803)
- Testing
- ABU bladder lavage, Saline bladder lavage
- Where
- 2 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Kidney Transplantation, Adult
Web-Based Multi-Resource Training on the Prevention of Urinary Tract Infections in Adult Kidney Transplant Recipients
Purpose: The study aims to examine the effect of web-based multi-source training on the prevention of urinary tract infections in adult kidney transplant recipients on clinical outcomes.
- Conditions
- Kidney Transplantation, Adult, Urinary Tract Infections, Prevention
- Trial name
- NCT05821946
- Testing
- Web-Based Multi-Source Training on the Prevention of Urinary Tract İnfections
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Urinary Tract Infection
Trial to Evaluate the Efficacy and Safety of Cipro® XR in Treating Female Patients With Lower Urinary Tract Infections
This trial evaluated how effective and safe Cipro XR was in treating female patients with signs and symptoms of a lower urinary tract infections.
- Trial name
- NCT00669994
- Testing
- Ciprofloxacin
- Where
- 31 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bayer
Urinary Tract Infection
Bacterial Interference for Prevention of Catheter-Associated UTI: Geriatric Pilot Study
This study is a prospective pilot clinical trial investigating the use of urinary catheters coated with benign E. coli in geriatric subjects.
- Trial name
- NCT00554996
- Testing
- E. coli 83972 coated urinary catheter
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Urinary Tract Infections
Reducing Antibiotic Prescriptions for Urinary Tract Infection in Long-Term Care Facilities
This cluster randomized controlled study evaluates the effect of a tailored observation, reflection and communication tool on used by long-term care facility staff on antibiotic prescription for urinary tract infection in…
- Trial name
- NCT03715062
- Testing
- Dialogue tool
- Where
- Denmark
- Volunteers
- 1,491 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
The Follow-up Duration Was 1-8 Years., The Main Reasons Behind Visiting the Hospital Were Recurrent Urinary Tract Infection,
Evaluation of Immunological Disorders of T Lymphocytes and Endocrinological Disorders as Pathogen Factors in Patients With Metaplasia of Urinary Bladder
Background: Squamous metaplasia refers to the pathological transformation of the urothelium leading to non-keratinised stratified squamous metaplasia (N-KSM).
- Conditions
- The Follow-up Duration Was 1-8 Years., The Main Reasons Behind Visiting the Hospital Were Recurrent Urinary Tract Infection,, Urinary Urgencies, Pollakiuria, Difficulty in Initiating Micturition, Pain in Hypogastrium,, Night Wetting and Day Wetting, Menstruation's Disorders, Urolithiasis, Defects of Urinary
- Trial name
- NCT02092558
- Testing
- Second-generation cephalosporin, nitrofurantoin, 1% aminoglycoside solution, cephalosporin with chemotherapeutics
- Where
- Poland
- Volunteers
- 2 people
- Sponsor
- Children's Hospital, Dziekanów Leśny, Poland
Renal Insufficiency
Association Between COVID-19 and UTIs Caused by ESBL Organism in Infants
Urinary tract infections (UTIs) in infants and young children are one of the most common bacterial infections, usually febrile illness without source, frequently due to Enterobacteriaceae, mainly Escherichia coli.
- Trial name
- ABCUCEOI (NCT05630326)
- Testing
- comparing, prevalence, assessment, association
- Where
- Qatar
- Volunteers
- 5,600 people
- Sponsor
- Hamad Medical Corporation
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Carbapenem Resistant Bacteria Infection
European Prospective Cohort Study on Enterobacteriaceae Showing Resistance to Carbapenems
Among antibiotic-resistant organisms, the Gram-negative bacteria are now the most important challenge because of the rapid worldwide spread of mechanisms conferring resistance to multiple drugs.
- Trial name
- EURECA (NCT02709408)
- Where
- 50 sites in Albania, Bulgaria and 9 more
- Volunteers
- 2,515 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Overactive Bladder, Overactive Detrusor
Sensitivity of Extended Cultures in Diagnosing Urinary Tract Infections
There is some evidence to suggest standard urine cultures may not be adequate in identifying patients with low grade urinary tract infections.
- Conditions
- Overactive Bladder, Overactive Detrusor, Urgency-Frequency Syndrome, UTI
- Trial name
- NCT03080389
- Testing
- Extended Urine Culture
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Urinary Tract Infections
Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's)
To investigate if administration of probiotics, either orally or vaginally, Can reduce the number of episodes of acute bacterial cystitis and/or Has tolerable adverse effect profile Improves general QoL in these women Improves…
- Trial name
- NCT00781625
- Testing
- UREX-cap-5
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- University Hospital, Akershus
Complicated Urinary Tract Infection
Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections
The purpose of this study is to determine whether NXL104 plus ceftazidime is effective in the treatment of complicated urinary tract infections as compared to a comparator group.
- Trial name
- NCT00690378
- Testing
- NXL104/ceftazidime, Imipenem/Cilastatin
- Where
- 59 sites in United States, Jordan and 1 more
- Volunteers
- 137 people
- Sponsor
- Pfizer
Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy
Effect of Vulvar Re-Antisepsis Before CO₂ Cystoscopy Performed After Laparoscopic Hysterectomy on Postoperative Urinary Infections
This prospective observational study aims to evaluate whether additional vulvar re-antisepsis before intraoperative cystoscopy reduces the incidence of postoperative urinary tract infections (UTIs) in patients undergoing total…
- Conditions
- Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy, Cystoscopy, Antisepsis
- Trial name
- NCT07232446
- Testing
- Additional Vulvar Re-Antisepsis Before Cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Alaattin Karabulut
Urinary Tract Infections, Urosepsis
Prevalence of Antimicrobial-resistant Pathogens in Patients Admitted for UTIs
Between 2013-2014, our study network of U.S. emergency departments, EMERGEncy ID NET, found that the rate of fluoroquinolone-resistant E. coli was 11.7% among all patients, 6.3% in uncomplicated and 19.9% in complicated.
- Trial name
- NCT03346603
- Testing
- urine culture and susceptibility testing
- Where
- United States
- Volunteers
- 801 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Urinary Retention, Urinary Incontinence
Reducing Postoperative Catheterization
After reconstructive pelvic surgery urinary retention occurs in up to 60% of patients requiring an indwelling catheter or self-catheterization (1-5).
- Conditions
- Urinary Retention, Urinary Incontinence, Pelvic Organ Prolapse, Urinary Tract Infections
- Trial name
- NCT03009968
- Testing
- Post-void residual free voiding trial
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Urinary Tract Infections
Treatment of Extended Spectrum Betalactamase Producing Bacteria Causing Urinary Tract Infections in General Practice
The prevalence of extended spectrum beta-lactamase (ESBL) producing bacteria found in urine sample cultures has been increasing over the past decades.
- Trial name
- NCT01531023
- Where
- 7 sites in Norway
- Volunteers
- 168 people
- Sponsor
- University of Oslo
Urinary Tract Infection (UTI)
The INSPIRE-ASP UTI Trial
The INSPIRE-ASP UTI trial is a cluster-randomized controlled trial of HCA hospitals comparing routine empiric antibiotic stewardship practices with real-time precision medicine computerized physician order entry smart prompts…
- Trial name
- NCT03697096
- Testing
- Routine Care, INSPIRE CPOE Smart Prompt
- Where
- 59 sites in United States
- Volunteers
- 55,412 people
- Sponsor
- Harvard Pilgrim Health Care
Recurrent UTIs, Catheter-Related Infections
Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children
Background: Urinary tract infections (UTIs) are a common and costly cause of doctor visits for children. Frequent UTIs trigger kidney damage that leads to serious diseases like high blood pressure, pregnancy complications, and…
- Trial name
- Nissle 1917 (NCT01696227)
- Testing
- Nissle 1917
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Pregnancy Complications
Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections
Urinary tract infection is the most common bacterial infection during pregnancy. Asymptomatic bacteriuria is the most common infection, in up to 8% of the population.
- Trial name
- NCT01507974
- Testing
- Preventive antibiotic treatment- NITROFURANTOIN, Preventive antibiotic treatment- CEPHALEXIN, PREVENTIVE TREATMENT- AMOXICILLIN
- Where
- Israel
- Volunteers
- 220 people
- Sponsor
- HaEmek Medical Center, Israel
All Conditions Causing Sepsis, Pneumonia - Bacterial
Comparison Between the Progostic Value of the Procalcitonin and the Platelet/Total Leukocytic Count Ratio in Sepsis
What is already known on this subject? AND What does this study add? Sepsis is a complicated condition caused by a malfunction of the host's immune response to infection, which results in an uncontrollable inflammatory response…
- Conditions
- All Conditions Causing Sepsis, Pneumonia - Bacterial, Urinary Tract Infection Bacterial
- Trial name
- NCT06991686
- Testing
- Blood samples, blood sample
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University