Clinical trials: Urinary Tract Infection (UTI)
Urinary Tract Infections
Ertapenem Administered Subcutaneously Versus Intravenously
Infections requiring intravenous antimicrobial therapy are very common events in patients with advanced cancer. Nevertheless, these patients frequently present vascular damages becoming extremely difficult to access and maintain…
- Trial name
- NCT03218800
- Testing
- Ertapenem
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Recurrent Clostridium Difficile Infection, Multidrug-resistant Klebsiella Pneumoniae Urinary Tract Infection
Fecal Microbiota Transplantation (FMT): PRIM-DJ2727
The Fecal Microbiota Transplantation (FMT) product PRIM-DJ2727 is prepared from human stool from a healthy, screened donor. Requestors will contact the study team about the product (PRIM-DJ2727) by email, visit, or phone call.
- Trial name
- NCT03786900
- Testing
- Fecal Microbiota Transplantation (FMT) product PRIM-DJ2727
- Sponsor
- Herbert DuPont, MD
Urologic Diseases, Patient Satisfaction
Developing a PROM for Recurrent Urinary Tract Infection
This study aims to develop and validate the first set of patient-reported outcome measures for recurrent urinary tract infection (UTI): the Recurrent UTI Symptom Scale and the Recurrent UTI Impact Questionnaire.
- Conditions
- Urologic Diseases, Patient Satisfaction, Pain, Chronic, Sexual Dysfunction
- Trial name
- NCT05086900
- Testing
- Non-interventional Cross-sectional Patient Reported Outcome Measure Development
- Where
- United Kingdom
- Volunteers
- 283 people
- Sponsor
- University of Reading
Schistosomiasis
Schistosoma Haematobium Infections and Praziquantel
The purpose of this study is to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan.
- Trial name
- NCT01558336
- Testing
- praziquantel
- Where
- Sudan
- Volunteers
- 520 people
- Sponsor
- University of Khartoum
Catheter-Associated Urinary Tract Infections (CAUTIs)
Evaluate of the Use of Uromune as a Potential Non-antibiotic Prophylactic Strategy for Catheter-associated Urinary Tract Infection in Patients With Long-term Catheterization.
A self-controlled pilot study to evaluate the use of oral bacterial immunotherapy for prevention of catheter-associated urinary tract infection.
- Trial name
- NCT07869992
- Testing
- Uromune
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Urinary Tract Infection
Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections
Study is planned to evaluate safety and efficacy of Levolet in patients with complicated UTI
- Trial name
- Levolet-KZ16 (NCT03160807)
- Testing
- Levofloxacin
- Where
- Kazakhstan
- Volunteers
- 214 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Urological System Complication of Procedure, Urinary Tract Infections
Effectiveness of Single Dose Fosfomycin and Single Dose Levofloxacin as Pre-urodynamic Antibiotic for UTI Prevention
The goal of this clinical trial is to compare the use of single dose fosfomycin and single dose levofloxacin as pre-urodynamic antibiotic prophylaxis for urinary tract infection prevention post-urodynamic in patients with lower…
- Trial name
- NCT06017479
- Testing
- Fosfomycin 3000 MG, Levofloxacin 500mg
- Where
- Indonesia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Urinary Tract Infection Complicated, Acute Pyelonephritis
Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults
Vabomere™, (meropenem-vaborbactam) is being compared to the Best Available Therapy in the treatment of adults with selected serious infections due to Carbapenem Resistant Enterobacteriaceae
- Conditions
- Urinary Tract Infection Complicated, Acute Pyelonephritis, Hospital Acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia
- Trial name
- NCT02168946
- Testing
- Vabomere, Best Available Therapy
- Where
- 50 sites in United States, Argentina and 6 more
- Volunteers
- 77 people
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.)
Urinary Tract Infections
The Effect of Sonographic Bladder Compressive Technique for Bag Urine Collection in Pediatrics
Aim: to shorten the time of urination by bladder pressure stimulation in children less than 36 months of age who need urinalysis to exclude or diagnose urinary tract infections and to speed up the start time of antibiotics…
- Trial name
- NCT03152851
- Testing
- Pressure stimulus group
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Recurrent Urinary Tract Infections, Urinary Tract Infections
WMT for Recurrent Urinary Tract Infections
his is a single-center, prospective, single-arm, interventional clinical study to evaluate the clinical efficacy, safety, and potential mechanisms of washed microbiota transplantation (WMT) in patients with recurrent urinary…
- Trial name
- WMT-rUTI (NCT07627412)
- Testing
- Washed Microbiota Transplantation (WMT)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Urinary Tract Infection, Asymptomatic Bacteriuria
De-implementing PreOp Urine Testing
This is a randomized study to evaluate the effectiveness and implementation of an intervention to decrease unnecessary urine testing for surgical patients (Less is More for Surgical Urine Testing) across six geographically…
- Trial name
- NCT07411209
- Testing
- Interventional Project Site Visit
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Sexually Transmitted Diseases, Bacterial, Bacterial Urinary Tract Infection
UROGEN WELL D-ONE : Evaluation of a Novel Diagnostic for Sexually Transmitted Bacterial Infections
UROGEN WELL D-ONE Principal research question: Can the UROGEN WELL D-ONE assay detect urinary tract infections and urethritis in clinical samples from patients attending Genitourinary Medicine outpatient clinics as accurately as…
- Conditions
- Sexually Transmitted Diseases, Bacterial, Bacterial Urinary Tract Infection, Antimicrobial Resistance
- Trial name
- NCT04182230
- Testing
- No intervention. This study was an evalution with no intervention.
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Cwm Taf University Health Board (NHS)
Acute Pyelonephritis, Complicated Urinary Tract Infection
Bacterial Metallophores in the Diagnosis of Acute Pyelonephritis
The project aims to investigate bacterial metallophores as potential diagnostic markers of acute pyelonephritis and complicated urinary tract infections.
- Trial name
- NCT05674032
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomayer University Hospital
Urinary Tract Infection Complicated, Kidney Stones
Resistance Characteristics and Development of Diagnostic Model for Postoperative UTI in Patients With Kidney Stones
The combined detection of HBP, ADPN, NGAL, and hs-CRP enables the construction of a highly efficient diagnostic model, offering a novel strategy for early infection identification and risk stratification after surgery.
- Conditions
- Urinary Tract Infection Complicated, Kidney Stones, Antimicrobial Resistance
- Trial name
- NCT06946667
- Testing
- the UTI group, the Non-UTI group
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Xingxin Jiang
Bacterial Vaginosis, Candidosis Vaginal
Lacticaseibacillus Rhamnosus CA15 (DSM 33960) Strain as a New Driver in Restoring the Normal Vaginal Microbiota
The aim of the present randomized double-blind placebo-controlled trial is to evaluate the efficacy of a probiotic formulation, containing the probiotic strain Lacticaseibacillus rhamnosus CA15 (DSM 33960), in the treatment of…
- Conditions
- Bacterial Vaginosis, Candidosis Vaginal, Urinary Tract Infections
- Trial name
- NCT05796921
- Testing
- Lacticaseibacillus rhamnosus CA15 (DSM 33960) probiotic strain
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Agnese Maria Chiara Rapisarda
Urinary Tract Infections, Malnutrition
Effect of Hygiene and Menstrual Hygiene Interventions on Learning and Psychosocial Wellbeing in Madagascar
A previous study in schools in rural Madagascar found that a bundle of hygiene-focused interventions substantially improved girls' learning outcomes.
- Conditions
- Urinary Tract Infections, Malnutrition, Inflammation, Stress
- Trial name
- KILONGA2 (NCT07702916)
- Testing
- Peer leadership/sensitization + sanitary pads, School infrastructure
- Where
- Madagascar
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- University of California Santa Cruz
Hospital-acquired Bacterial Pneumonia (HABP), Ventilator-associated Bacterial Pneumonia (VABP)
Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in Carbapenem-Resistant Enterobacteriaceae Infections
The study will evaluate the efficacy and safety of Meropenem and Pralurbactam versus Best Available Therapy in the treatment of Carbapenem-Resistant Enterobacteriaceae Infections.
- Conditions
- Hospital-acquired Bacterial Pneumonia (HABP), Ventilator-associated Bacterial Pneumonia (VABP), Complicated Intra-abdominal Infection (cIAI), Complicated Urinary Tract Infection (cUTI)
- Trial name
- NCT07089186
- Testing
- Meropenem and Pralurbactam, Best Available Therapy (e.g., colistin, meropenem, tegecycline, amikacinceftezidime-avibatam)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Urinary Tract Infections
Effects of Flourish on Recurrent Urinary Tract Infection
An over-the-counter vaginal care system is being tested to see if it may be effective in preventing recurrence of symptomatic urinary tract infection (UTI) in women who have had multiple UTIs within the past year.
- Trial name
- NCT05397782
- Testing
- BioNourish, a component of Flourish HEC
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Vaginal Biome Science
Urinary Tract Infections, Urinary Retention
Can Investigators Reduce Urinary Catheter Use and Lower Urinary Tract Infection Among Women Undergoing Benign Gynecologic Surgery?
This is a randomized comparative trial investigating two different catheter management strategies among post-gynecologic surgery patients.
- Conditions
- Urinary Tract Infections, Urinary Retention, Satisfaction
- Trial name
- CAUTI (NCT03127280)
- Testing
- Fast Track foley removal
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Christ Hospital
Urinary Tract Infections, Recurrent Urinary Tract Infection
Patient Satisfaction and Long-term Safety of Intravesical Aminoglycoside Instillations in UTI Prevention
Antimicrobial prophylactic treatment of recurrent UTI is limited by emerging resistance, antibiotic allergies and intolerances. Intravesical aminoglycoside instillations (IAI) have been shown to reduce recurrence rate, without a…
- Trial name
- INSTILMENT (NCT05376670)
- Testing
- Intravesical aminoglycoside instillations
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Leiden University Medical Center