Clinical trials: Urinary Tract Infection (UTI)
Neurogenic Bladder
Incidence of Urinary Tract Infection After Urodynamic Investigation
The purpose of this study is to evaluate the incidence of urinary tract infection after urodynamic investigation and to identify the involved germs.
- Trial name
- NCT01297647
- Testing
- urodynamic examination
- Where
- Switzerland
- Volunteers
- 317 people
- Sponsor
- Balgrist University Hospital
Respiratory Tract Infections, Urinary Tract Infections
HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study
This study will analyze gene expression data (HostDx Sepsis test) from blood samples collected from participants with suspected infections.
- Conditions
- Respiratory Tract Infections, Urinary Tract Infections, Skin and Soft Tissue Infections, Intraabdominal Infections
- Trial name
- NCT03744741
- Testing
- HostDx Sepsis
- Where
- 7 sites in United States, Greece
- Volunteers
- 585 people
- Sponsor
- Inflammatix
Urinary Tract Infections
Bladder Stimulation Technique for Clean Catch Urine Collection in Infants
Urinary tract infection is the most common serious bacterial infection among infants. Bladder catheterization is considered the gold standard for diagnosis, yet is painful and invasive.
- Trial name
- NCT03174834
- Testing
- Bladder Stimulation technique
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Michigan
Infection, Hospital, Antimicrobial
Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units
Healthcare-associated infections (HAIs) remain a major problem in intensive care units (ICUs), driven by environmental contamination with multidrug-resistant organisms that persist despite routine manual cleaning.
- Conditions
- Infection, Hospital, Antimicrobial, Pneumonia Associated With Mechanical Ventilation, Urinary Tract Infection(UTI)
- Trial name
- Hylight (NCT07233837)
- Testing
- Aerosol of hydrogen peroxide, Irradiation of ultraviolet light
- Where
- 12 sites in Brazil
- Volunteers
- 5,000 people
- Sponsor
- Hospital Israelita Albert Einstein
Acute Pyelonephritis, Complicated Urinary Tract Infection
Bacterial Metallophores in the Diagnosis of Acute Pyelonephritis
The project aims to investigate bacterial metallophores as potential diagnostic markers of acute pyelonephritis and complicated urinary tract infections.
- Trial name
- NCT05674032
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomayer University Hospital
Pneumonia, Urinary Tract Infections
BetaLACTA® Test for Early De-escalation of Empirical Carbapenems in Pulmonary, Urinary and Bloodstream Infections in ICU
The emergence and rapid worldwide spread of Extended- Spectrum Beta-Lactamase-producing enterobacteriaceae (ESBLE) both in hospital and community, led physicians, and notably intensivists, to prescribe more carbapenems…
- Conditions
- Pneumonia, Urinary Tract Infections, Bloodstream Infection
- Trial name
- BLUE-CarbA (NCT03147807)
- Testing
- betaLACTA® rapid diagnostic test
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bacterial Infections, Urinary Tract Infections
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers
This Phase I study is a randomized, double-blind, placebo-controlled, dose-escalation trial conducted at a single center. It consists of two parts: Part 1 (SAD): Evaluates the safety, tolerability, and pharmacokinetics (PK) of…
- Conditions
- Bacterial Infections, Urinary Tract Infections, Intra-Abdominal Infections, Respiratory Tract Infections
- Trial name
- NCT07207291
- Testing
- JKN2501
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd
Recurrent Urinary Tract Infection, Hypoestrogenism
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn about medication adherence to difference types of vaginal estrogen in women with low levels of estrogen (for example, post-menopausal women) who have recurrent urinary tract infections.
- Trial name
- NCT06353269
- Testing
- Estring Vaginal Product, Vagifem, Estrace 0.01% Vaginal Cream
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Complicated Urinary Tract Infection, Acute Pyelonephritis
A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)
This was a randomized, multicenter, multinational, double-blind study comparing the efficacy and safety of plazomicin compared with meropenem followed by optional oral (PO) therapy in the treatment of cUTI, including AP, in…
- Trial name
- EPIC (NCT02486627)
- Testing
- plazomicin, meropenem, levofloxacin (oral)
- Volunteers
- 609 people
- Sponsor
- Achaogen, Inc.
Urinary Tract Infection
To Study the Effect of Adjunctive Oral Methylprednisolone Therapy in Pediatric Urinary Tract Infection
Purposes of this study will be as follows: 1. To design a prospective, randomized, and open-labeled study to investigate the effect and the side effect of MPD in combination with conventional antibiotics to affect clinical…
- Trial name
- NCT02331862
- Testing
- Methylprednisolone
- Volunteers
- 160 people
- Sponsor
- National Cheng-Kung University Hospital
Urinary Tract Infection, Pyelonephritis
Pharmacokinetics of Ciprofloxacin in Pediatric Patients
Measuring serum and urine concentrations of ciprofloxacin after IV and oral administration in children aged 3 months - 17 years who are treated for urinary tract infections.
- Trial name
- NCT02598362
- Testing
- ciprofloxacin
- Where
- 2 sites in Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital, Ghent
Urinary Tract Infections, Urological System Complication of Procedure
Potentiated Aminoglycosides in Postoperative Urinary Tract Infection Prophylaxis
Urinary tract hardware such as pig-tail catheters are are frequently used for management of urolithiasis or other obstructive pathologies. They are readily colonized by urogenital flora leading to asymptomatic bacteriuria.
- Trial name
- UROPOT (NCT05761405)
- Testing
- mannitol-enhanced aminoglycoside, Ceftriaxon, Amikacin
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Uncomplicated Urinary Tract Infections, Urinary Tract Infections
Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract Infections
This phase 1b study is a double-blind, double-dummy, nitrofurantoin-controlled study designed to evaluate microbiological response at the test of cure (ToC) visit along with safety, tolerability and pharmacokinetic (PK) response…
- Trial name
- NCT05138822
- Testing
- GSK3882347, Nitrofurantoin
- Where
- 15 sites in United States
- Volunteers
- 140 people
- Sponsor
- GlaxoSmithKline
Urinary Tract Infection
The Clinical Impact of Isolation of Two Different Bacteria in Urinary Cultures
The purpose of this study is to determine whether identification of two different bacteria in urine culture of patients with indwelling catheter has a clinical impact - change in antibiotic, duration of antibiotic, days to…
- Trial name
- NCT01060956
- Testing
- reporting of two different bacteria in urine culture, reporting "mixed growth" on urine culture
- Volunteers
- 81 people
- Sponsor
- Shaare Zedek Medical Center
Infective Complications Post-transrectal Prostate Biopsy
Prostate Biopsy Antisepsis
During a prostate biopsy, a needle is guided through the rectum into the prostate. Although patients are given antibiotics before the biopsy, there is still a risk of bacteria getting from the rectum into the bladder, prostate…
- Trial name
- NCT00999427
- Testing
- Povidone-iodine
- Where
- 3 sites in Canada
- Volunteers
- 865 people
- Sponsor
- University of British Columbia
Urinary Tract Infections
Nitrofurantoin and Urinary Tract Infections (UTIs)
Urinary tract infection (UTI) is the most common complication after surgery for prolapse or urinary incontinence. UTIs are painful and have the potential to turn into kidney infections.
- Trial name
- APPIC (NCT00678041)
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Urinary Tract Infections
Single Dose Amikacin for Uncomplicated Cystitis in the ED: A Feasibility Study
The purpose of this study is to determine if a single dose of amikacin (a type of antibiotic) can be used to effectively treat emergency department patients with uncomplicated cystitis (inflammation of the bladder).
- Trial name
- NCT05227937
- Testing
- Amikacin
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Urinary Tract Infections, Pelvic Organ Prolapse
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery
We aim to compare the effectiveness of cranberry capsules versus nitrofurantoin prophylaxis in preventing urinary tract infections (UTIs) after urogynecologic surgery by conducting a double-blinded randomized clinical trial…
- Conditions
- Urinary Tract Infections, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- NCT03522961
- Testing
- Cranberry capsules
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Brigham and Women's Hospital
Urinary Tract Infections
Interactions Between Cranberry Juice and Antibiotics Used to Treat Urinary Tract Infections
The purpose of study is to determine whether cranberry juice interacts with antibiotics used to treat urinary tract infections (UTIs).
- Trial name
- NCT00084201
- Testing
- Cranberry juice, Amoxicillin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acute Pyelonephritis
Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection
Hypothesis: Administration of corticoids (dexamethasone) together with the conventional antibiotherapy in the acute phase of a febrile urinary tract infection could reduce the risk of renal scarring after 6 months of the…
- Trial name
- DEXCAR-0212 (NCT02034851)
- Where
- 7 sites in Spain
- Volunteers
- 183 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili