Clinical trials: Urinary Tract Infection Bacterial
Bacterial Infections, Urinary Tract Infections
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers
This Phase I study is a randomized, double-blind, placebo-controlled, dose-escalation trial conducted at a single center. It consists of two parts: Part 1 (SAD): Evaluates the safety, tolerability, and pharmacokinetics (PK) of…
- Conditions
- Bacterial Infections, Urinary Tract Infections, Intra-Abdominal Infections, Respiratory Tract Infections
- Trial name
- NCT07207291
- Testing
- JKN2501
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd
Enterobacteriaceae Infections, Bacteremia
Infections Caused by ESbL-Producing Enterobacteriaceae in Italy
To assess the molecular epidemiology, clinical impact, treatment outcome and risk factors for infections caused by Enterobacteriaceae producing ESBLs in Italy in a large multicenter observational survey. SPECIFIC OBJECTIVES 1.
- Conditions
- Enterobacteriaceae Infections, Bacteremia, Pneumonia, Skin Diseases
- Trial name
- NCT00404625
- Testing
- Risk factors for infections due to ESBL+ Enterobacteriaceae, Risk factors for inadequate initial antimicrobial therapy, Overall and 30-day mortality in bad first antibiotic therapy
- Where
- 6 sites in Italy
- Volunteers
- 813 people
- Sponsor
- University of Siena
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Urinary Infection
Dynamics of the Urinary Bacterial Microbiota
Urinary tract infections (UTIs) are one of the most common bacterial infections in humans (Flores-Mireles et al., 2015). They rank first among healthcare-associated infections (Daniau et al., 2020) and second among…
- Trial name
- DAIQUIRI (NCT07020676)
- Where
- France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Bacterial Vaginosis, Oxaluria
The Effects of Cranberry Juice on Bacterial Adhesion
The study is based on the hypothesis that consumption of cranberry juice products results in the production of metabolites in the urine that have anti-adhesive properties on bacteria.
- Trial name
- NCT00318253
- Testing
- cranberry juice
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Infection Due to ESBL Escherichia Coli
Fosfomycin Versus Meropenem or Ceftriaxone in Bacteriemic Infections Caused by Multidrug Resistance in E.Coli
Enterobacterieaceae (and specially Escherichia coli) showing resistance due to multidrug-resistant Escherichia coli, plasmid mediated AmpC or quinolone resistance caused by chromosomal mechanisms have spread worldwide during the…
- Trial name
- FOREST (NCT02142751)
- Testing
- Fosfomycin sodium intravenous, Meropenem intravenous, Ceftriaxone intravenous
- Where
- 22 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Bladder Cancer, Transurethral Resection of the Bladder
Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial
The main objective of the study is to demonstrate that not performing a systematic UC before the TURB procedure is non-inferior to performing a systematic UC in terms of the incidence of febrile UTIs during the first 30…
- Conditions
- Bladder Cancer, Transurethral Resection of the Bladder, Urinary Tract Infection Bacterial
- Trial name
- RUPTURE (NCT07463963)
- Testing
- Urine bacterial Culture (UC), No intervention before TURB surgery
- Where
- 15 sites in France
- Volunteers
- 2,600 people
- Sponsor
- Poitiers University Hospital
Chronic Interstitial Cystitis, Painful Bladder Syndrome
Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder
Pilot study to determine feasibility for treating patients with two chronic inflammatory conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract infections using a standardized hyperbaric…
- Conditions
- Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- HBOTCICrUTI (NCT03143920)
- Testing
- Hyperbaric Oxygen Therapy-
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Diego
Urinary Tract Infections (UTIs)
Sensitivity of Antibiotics for Urinary Tract Infections Patients Attending Family Physicians
This study is aiming to evaluate the sensitivity of uropathogens isolated in patients with community acquired UTI with Enoxacin in comparison to other antimicrobials.
- Trial name
- NCT02305342
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Abbott
Urinary Tract Infections, Recurrent Urinary Tract Infections
WMT for Multidrug-Resistant Organism UTI
This is a single-center, prospective, single-arm, exploratory clinical study to evaluate the efficacy, safety, and potential mechanisms of washed microbiota transplantation (WMT) in patients with recurrent urinary tract…
- Conditions
- Urinary Tract Infections, Recurrent Urinary Tract Infections, Multidrug-Resistant Bacterial Infections, Bacteriuria
- Trial name
- NCT07816913
- Testing
- Washed Microbiota Transplantation (WMT)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Bacterial Urinary Tract Infection
Female Urogenital Nutrition- Health Study
The purpose of this study is to assess nutrition and urinary tract bacterial activity during menstruation of approximately 15 female university Reserve Officer Training Corps (ROTC) cadets and Phoenix area police officers…
- Trial name
- FUN-Health (NCT05015400)
- Testing
- Plain Water
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Urinary Tract Infections, Bacterial Resistance
Study to Assess Management and Outcomes of Hospitalised Patients With Complicated UTI (RESCUING)
A retrospective observational study to assess the clinical management and outcomes of hospitalised patients with complicated urinary tract infection in countries with high prevalence of multidrug resistant gram-negative bacteria…
- Trial name
- RESCUING (NCT02641015)
- Where
- 21 sites in Bulgaria, Greece and 6 more
- Volunteers
- 1,028 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Urinary Tract Infections
Evaluation of the Prevalence of E. Coli O Serotypes in Paediatric Population With Recurrent Urinary Tract Infection
This is a multicentre, observational, epidemiological study in which infants within the first 3 months of life with UTI and children aged ≥4 months with r-UTI will be recruited from nephrology /emergency departments and primary…
- Trial name
- rUTI (NCT06482151)
- Sponsor
- PENTA Foundation
Antimicrobial Resistance (AMR)
NCCR AntiResist:: New Approaches to Combat Antibiotic-resistant Bacteria
This is an explorative, mono-center study including prospectively collected patient samples from the University Hospital of Basel.
- Trial name
- AntiResist (NCT05017766)
- Testing
- analysis of antimicrobial resistance
- Where
- Switzerland
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Bloodstream Infections (BSI) Due to CRE, Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE
A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)
This was a Phase 3 study containing a randomized open-label superiority cohort (Cohort 1) comparing the efficacy and safety of plazomicin with colistin when combined with a second antibiotic (either meropenem or tigecycline) in…
- Conditions
- Bloodstream Infections (BSI) Due to CRE, Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE, Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE, Complicated Urinary Tract Infection (cUTI) Due to CRE
- Trial name
- CARE (NCT01970371)
- Testing
- plazomicin, colistin, meropenem
- Volunteers
- 69 people
- Sponsor
- Achaogen, Inc.
Urinary Tract Infection Complicated, Acute Pyelonephritis
CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria
The purpose of this study is to evaluate the effects of CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) compared to Meropenem for treating hospitalized patients with complicated urinary tract infections, including acute pyelonephritis…
- Trial name
- PLEA (NCT03477422)
- Testing
- CSE-1034 (Ceftriaxone + Sulbactam + EDTA), Meropenem
- Where
- 17 sites in India
- Volunteers
- 230 people
- Sponsor
- Venus Remedies Limited
Recurrent Urinary Tract Infections in Women
Prophylactic Use of Cranberries in Recurrent Bacterial Cystitis in Women
To investigate if oral administration of 240mg PAC of cranberries can reduce the number of episodes of acute bacterial cystitis and improve general QoL in women with recurrent bacterial cystitis.
- Trial name
- NCT03032003
- Testing
- Cysticlean
- Volunteers
- 160 people
- Sponsor
- University of Thessaly
Gram-negative Bacteremia, Urinary Tract Infection Bacterial
Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia
GNB5 is an investigator-initiated multicentre non-inferiority randomized controlled trial which aims to assess the efficacy and safety of shortened antibiotic for patients hospitalized with a Gram negative bacteremia with a…
- Trial name
- GNB5 (NCT04291768)
- Testing
- Shortened antibiotic treatment, Standard antibiotic treatment
- Where
- 13 sites in Denmark
- Volunteers
- 380 people
- Sponsor
- Thomas Benfield
Urinary Tract Infection, Cellulitis
Perspectives on Antibiotics and Tracking Symptoms in Children
The study will assess families' perspectives and decision-making regarding the duration of oral antibiotic courses prescribed to children (4-17 years) who present with uncomplicated bacterial infections at the Royal Children's…
- Conditions
- Urinary Tract Infection, Cellulitis, Impetigo, Pharyngitis
- Trial name
- PATSy (NCT07093749)
- Testing
- Garmin Smartwatch
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Complicated Urinary Tract Infections, Antibiotic Resistance
Cefepime/Enmetazobactam for Bacteremic Complicated Urinary Tract Infections
This study is designed to better understand how well a new antibiotic combination, cefepime/enmetazobactam (FEP/META), works in patients with complicated urinary tract infections that have spread to the bloodstream (bacteremia).
- Trial name
- CP-CUTI (NCT07725848)
- Where
- 3 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna