Clinical trials: Urinary Tract Infections
Infections, Bacterial
Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)
Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor that is being developed for the treatment of uncomplicated urinary tract infections (UTIs; acute cystitis).
- Trial name
- NCT03568942
- Testing
- Gepotidacin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- GlaxoSmithKline
Complicated Urinary Tract Infections
Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults
This is a prospective, phase 3, randomized, multicenter, double-blind, double-dummy study to compare the efficacy and safety of sulopenem followed by sulopenem-etzadroxil/probenecid versus ertapenem followed by ciprofloxacin for…
- Trial name
- NCT03357614
- Testing
- Sulopenem, Sulopenem-Etzadroxil/Probenecid, Ertapenem
- Where
- 32 sites in United States, Estonia and 3 more
- Volunteers
- 1,395 people
- Sponsor
- Iterum Therapeutics, International Limited
Healthy
A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and Separately
This is a randomised study divided into 2 parts. Part A investigates the effect of prolonged dosing (ten days) with Avibactam and Ceftazidime when given together and how this will effect how much Avibactam and Ceftazidime enters…
- Trial name
- NCT01430910
- Testing
- CAZ104, Avibactam, Ceftazidime
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pfizer
Urinary Tract Infections
Effect of Probiotics on Recurrent Urinary Tract Infections
Randomized clinical trial to evaluate the effect of a probiotic mixture of Lactobacillus plantarum on recurrent urinary tract infections in women.
- Trial name
- CYSCARE (NCT06192966)
- Testing
- Food supplement
- Where
- 4 sites in Spain
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis
Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)
The purpose of this study is to evaluate the effects of Ceftazidime Avibactam compared to Doripenem for treating hospitalized patients with complicated urinary tract infections, including acute pyelonephritis
- Trial name
- NCT01599806
- Testing
- Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral)
- Where
- 57 sites in United States, Argentina and 15 more
- Volunteers
- 641 people
- Sponsor
- Pfizer
Urinary Retention, Catheter-Associated Urinary Tract Infection
Effectiveness and Cost-effectiveness of the T-Control® Catheter in Patients With Acute Urine Retention
The general purpose of this study is to assess the preliminary effectiveness and cost-effectiveness of the T-Control® catheter versus the Foley type catheter in patients with Acute Urine Retention.
- Conditions
- Urinary Retention, Catheter-Associated Urinary Tract Infection, Catheter Complications
- Trial name
- NCT05643950
- Testing
- Foley catheter, T-Control catheter
- Where
- 2 sites in Spain
- Sponsor
- Rethink Medical SL
Infections, Urinary Tract
A Bioequivalence Study of Cefadroxil Film Coated Tablets After A Single Oral Dose Administration to Healthy Subjects
This is an open-label, randomized, single dose, two-sequence two-period crossover study, separated by 7 days washout interval from the first Study Drug Administration.
- Trial name
- NCT02446496
- Testing
- Cefadroxil tablets manufactured by GSK, Cefadroxil tablets manufactured by NP
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Schistosoma Haematobium
Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis
The purpose of this study is to evaluate the efficacy of praziquantel versus As+SMP (Co-Arinate FDC ®) in the treatment of Schistosoma haematobium in 6-15 year old Malian children.
- Trial name
- NCT00510159
- Testing
- Artesunate+Sulfamethoxypyrazine/pyrimethamin, Praziquantel
- Where
- Mali
- Volunteers
- 800 people
- Sponsor
- Dafra Pharma
Recurrent Urinary Tract Infection
Nutritional Supplementation for Recurrent Urinary Tract Infections in Women
The study will test the ability of specially formulated nutritional supplement capsules to extend the time between recurrent urinary tract infections in women.
- Trial name
- NCT03597152
- Testing
- WelTract
- Volunteers
- 250 people
- Sponsor
- AmPurity Nutraceuticals, LLC
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Urinary Tract Infection Lower Acute
Efficacy and Tolerability of a Phytotherapy Combination (Aqualibra) in Patients With Uncomplicated Cystitis
This randomized, placebo-controlled, double-blind study investigated the efficacy and safety of the herbal medicinal product containing a combination of extracts of restharrow root (Ononidis radix), Java tea (Orthosiphonis…
- Trial name
- AquUTI (NCT04032574)
- Testing
- Herbal Medicinal Product
- Volunteers
- 200 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Complicated Urinary Tract Infection Including Acute Pyelonephritis
A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
- Trial name
- NCT04505683
- Testing
- Benapenem, Ertapenem
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Sihuan Pharmaceutical Holdings Group Ltd.
Schistosoma Hematobium Infection, Schistosomiasis Mansoni
Safety and Efficacy of Mirazid for Schistosomiasis Treatment
Clinical Trial Phase:Phase III Primary Objectives: Compare Mirazid and Praziquantel cure rates for both Schistosoma species. Compare Mirazid and Praziquantel effect in lowering the intensity of infection for both Schistosoma…
- Trial name
- PHAR0211 (NCT01529710)
- Testing
- Myrrh
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Pharco Pharmaceuticals
COVID-19, Infectious Disease
Continuous Temperature Telemonitoring of Patients With COVID-19 and Other Infectious Diseases in Hospital at Home Using Viture
The aim of this cohort study is to validate Viture®, a continuous temperature telemonitoring system, evaluating the level of agreement with a standard commercially available digital axillary thermometer.
- Conditions
- COVID-19, Infectious Disease, Tract Infection, Urinary, Bacteremia
- Trial name
- Viture (NCT05959928)
- Testing
- Continuous wearable thermometer placed on patient's armpit to monitor body temperature remotely
- Where
- Spain
- Volunteers
- 208 people
- Sponsor
- Vitio Medical S.L.
Urinary Tract Infections
A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections
The purpose of this study was to determine the efficacy and safety of intravenous cefiderocol (S-649266) in hospitalized adults with complicated urinary tract infections caused by Gram-negative pathogens.
- Trial name
- APEKS-cUTI (NCT02321800)
- Testing
- Cefiderocol, Imipenem/cilastatin
- Volunteers
- 452 people
- Sponsor
- Shionogi
Stress Urinary Incontinence
LIBERATE International
This is a prospective, randomized, double-blind, sham-controlled clinical study. The study is designed to demonstrate that active is superior to sham for the efficacy endpoints and is deemed to have appropriate safety as compared…
- Trial name
- NCT03619174
- Testing
- Viveve Treatment
- Where
- 6 sites in Canada
- Volunteers
- 99 people
- Sponsor
- Viveve Inc.
Urinary Tract Infections
A Comparative, Controlled Study to Evaluate the Clinical Accuracy of the Velieve U.S. UTI Urine Analysis Test System
The Velieve U.S. UTI Urine Analysis Test System (henceforth Velieve U.S.) is composed of a kit and a smartphone application. The device will be provided to the subject in a simulated home-use environment.
- Trial name
- NCT04371159
- Testing
- Velieve U.S.
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Healthy.io Ltd.
Urinary Tract Infection
Efficacy of CLR Compared to Fosfomycin Trometamol in Acute Lower uUTIs
To demonstrate non-inferiority of a non-antibiotic therapy with CLR versus an antibiotic treatment with fosfomycin trometamol in women suffering from acute lower uUTIs as measured by the proportion of patients who received an…
- Trial name
- NCT02639520
- Testing
- Canephron® N, Fosfomycin trometamol
- Where
- Germany
- Volunteers
- 659 people
- Sponsor
- Bionorica SE
Urinary Tract Infections
Phase II Proof of Concept Study in Uncomplicated UTI
A study of the efficacy and safety of MPC-SHRC for the relief of symptoms associated with uncomplicated urinary tract infections.
- Trial name
- NCT03129295
- Testing
- MPC-SHRC
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Mission Pharmacal