Clinical trials: Urinary Tract Obstruction
Losartan Adverse Reaction, Uropathy
The Effect of Losartan on the Recoverability of Renal Function in Anuric and Oliguric Patients With Unilateral Obstructed Kidney
Previous experimental studies concluded that angiotensin receptor blockers can ameliorate the harmful inflammatory and histological changes after relief of obstruction.
- Conditions
- Losartan Adverse Reaction, Uropathy, Uropathy Obstructive
- Trial name
- NCT04278495
- Testing
- Cozaar (Losartan Potassium 25mg)
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Bladder Outlet Obstruction
Urinary CTGF in Benign Prostatic Obstruction
Benign prostatic obstruction (BPO) is one of the most common causes of bladder outlet obstruction (BOO) and may lead to progressive structural and functional alterations in the bladder over time.
- Conditions
- Benign Prostatic Hyperplasia, Bladder Outlet Obstruction, Lower Urinary Tract Symptom
- Trial name
- NCT07416981
- Volunteers
- 50 people
- Sponsor
- Tarik Emre Sener
Urologic Injuries, Disorder of Urinary Stent
Indwelling Stent Discoloration Project
The aim of this study is to identify the root cause for the significant discolouration of Boston Scientific Percuflex based stents.
- Conditions
- Urologic Injuries, Disorder of Urinary Stent, Kidney Calculi, Urinary Tract Obstruction Due to Specified Cause
- Trial name
- NCT02007980
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
BPH With Urinary Obstruction, Male
HoLEP vs BPRP in the Management of a Large Volume (> 80 gm) Symptomatic BPH
To compare bipolar resection versus holmium laser enucleation for management of symptomatic large BPH (> 80 gm)
- Trial name
- NCT04935151
- Testing
- holmium laser enucleation of the prostate, Bipolar resection of the prostate
- Where
- 2 sites in Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Fecal Impaction, Lower Urinary Tract Disorder
Development of Fecal Scoring for the Management of Fecal Impaction With Regards to Lower Urinary Tract Dysfunction
The role of bowel bladder disorder, or BBD, has been highlighted as a major player in vesicoureteral reflux and urinary tract infection (UTI).
- Conditions
- Fecal Impaction, Lower Urinary Tract Disorder, Bladder Dysfunction, Bowel Dysfunction
- Trial name
- NCT04579731
- Testing
- Lactitol Monohydrate
- Where
- South Korea
- Volunteers
- 187 people
- Sponsor
- Seoul National University Hospital
Acute Renal Failure, Anuria
Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria
To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.
- Conditions
- Acute Renal Failure, Anuria, Obstructive Uropathy, Ureteric Stones
- Trial name
- NCT02139059
- Testing
- initial urinary drainage, direct ureteroscopy
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Kidney Stone, Kidney Calculi
Evaluation of Infection in Obstructing Urolithiasis
Obstructing urolithiasis can be life-threatening in the setting of urinary tract infection. The purpose of this study is to identify and validate risk factors and markers for the presence of infection and development of sepsis…
- Conditions
- Kidney Stone, Kidney Calculi, Urinary Tract Obstruction, Infection
- Trial name
- eIOU (NCT04332861)
- Testing
- Initial clinical and laboratory evaluation
- Where
- 2 sites in United States
- Volunteers
- 477 people
- Sponsor
- University of Texas Southwestern Medical Center
Urethral Obstruction
Standardized Prenatal Clinical Care for LUTO
The investigators propose a standardized prenatal management, based on the scientific evidence published in the literature, to manage prenatally fetuses with lower urinary tract obstruction (LUTO).
- Trial name
- NCT02315521
- Testing
- Fetal Intervention for LUTO
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Urinary Incontinence
The Effect of Ultrasound Guided Pudendal Block on Postoperative Analgesia in Urogynecological Surgeries
Stress urinary incontinence (SUI) is one of the most common problems encountered in gynecology outpatient clinics and affects approximately 4% to 35% of women.
- Trial name
- NCT07029087
- Testing
- Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Giresun University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Greenlight Vaporization vs Xpeeda Vaporesection
Bothersome lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) is a common problem, which impact patients' quality of life.
- Trial name
- NCT04386941
- Testing
- Xpeeda Fibre Laser Vaporesection of the Prostate, Greenlight XPS Vaporization of the Prostate
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Kidney Transplant; Complications, Kidney Transplant Infection
Early vs Late Urinary Catheter Removal After Renal Transplantation
The purpose of this study is to compare frequency of UTI, urine leak and need for reoperation in patients after renal transplant with early or delayed Foley catheter removal.
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Infection, Urinary Fistula, Urinary Tract Infections
- Trial name
- ELUCATR (NCT04815954)
- Testing
- Urinary catheter removal
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
Benign Prostatic Hyperplasia, Bladder Outlet Obstruction
Thulium Laser Enucleation With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia
This study will evaluate the safety and effectiveness of different surgical treatments for men with small-volume benign prostatic hyperplasia (BPH).
- Conditions
- Benign Prostatic Hyperplasia, Bladder Outlet Obstruction, Lower Urinary Tract Symptoms (LUTS)
- Trial name
- ThuLEP-BNI (NCT07569874)
- Testing
- Thulium Laser Enucleation of the Prostate Combined With Bladder Neck Incision, Thulium Laser Enucleation of the Prostate, Transurethral Resection of the Prostate
- Where
- China
- Volunteers
- 932 people
- Sponsor
- Chinese PLA General Hospital
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Benign Prostatic Hyperplasia With Outflow Obstruction, Lower Urinary Tract Obstructive Syndrome
Association of Urine BDNF and NGF With Lower Urinary System Parameters
Histologically, BPH is a benign proliferative process involving both epithelial and stromal elements and is characterised by progressive enlargement of the prostate.
- Trial name
- NCT06265519
- Testing
- Holmium laser enucleation of the prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction
Bipolar Resection vs Enucleation of Prostate
The aim of this study is to evaluate efficacy and safety of transurethral resection of the prostate and bipolar enucleation of the prostate.
- Conditions
- Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction, Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
- Trial name
- TURP vs BiTUEP (NCT06983444)
- Testing
- TURP, TUEP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
WATER III: Aquablation vs. Transurethral Laser Enucleation of Large Prostates (80 - 180mL) in Benign Prostatic Hyperplasia
Comparative analysis of efficacy and safety of Aquablation (AQUABEAM Robotic System®, PROCEPT BioRobotics, Redwood City, CA, USA) and transurethral laser enucleation as surgical therapy for benign prostatic hyperplasia with large…
- Trial name
- WATER III (NCT04801381)
- Testing
- Aquablation therapy, Transurethral laser enucleation
- Where
- 5 sites in Germany, United Kingdom
- Volunteers
- 202 people
- Sponsor
- University of Bonn
Benign Prostatic Hypertrophy With Outflow Obstruction, Overactive Detrusor
Prognostic Value of the Urinary Nerve Growth Factor in the Patients With Benign Prostatic Hyperplasia
Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients.
- Trial name
- NCT01781117
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Holmium laser enucleation system and morcellator
- Where
- South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- KYU-SUNG LEE
Stress Urinary Incontinence, Intrinsic Sphincter Deficiency
Local Anesthesia Before Bulkamid Injection
While recommended pre-anesthesia for polyacylamide hydrogel (PAHG, Bulkamid) injections for stress urinary incontinence and intrinsic sphincter deficiency can include intraurethral anesthetic gel with or without periurethral…
- Trial name
- LAB (NCT06043063)
- Testing
- Topical lidocaine, EMLA cream, Periurethral block
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Medstar Health Research Institute
Urethra Stricture
LishitonglinUS-01 Trial
This study intends to conduct a prospective, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of Lishi Tonglin Granule (a hospital-formulated innovative prescription) developed in our…
- Trial name
- NCT07769060
- Testing
- Lishitonglin Formula granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University First Hospital
Pneumothorax, Intestinal Obstruction
The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic Performance
This study tests whether an artificial intelligence (AI) tool helps radiologists read X-rays more accurately. Radiologists read X-rays to find diseases such as pneumonia, bone fractures, and abdominal problems.
- Conditions
- Pneumothorax, Intestinal Obstruction, Spondylolysis, Renal Calculus
- Trial name
- NCT07870928
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University