Clinical trials: Urinary Tract Stones
Kidney Stones
Flexible Ureteroscopy Versus Extracorporeal Shock Wave Lithotripsy
To compare the efficacy and safety of flexible ureterorenoscopy (fURS) versus extracorporeal shock wave lithotripsy (ESWL) in managing lower calyceal renal stones ≤15 mm and <1000 HU.
- Trial name
- NCT07193940
- Testing
- Flexible Ureteroscopy, extracorporeal shock wave lithotripsy (ESWL)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Renal Calculi
The 18F Peel-way Sheath Versus the 18F Access Sheath With a Suction-evacuation Function MPCNL for the Management of 2-5cm Size Kidney Stones
Percutaneous nephrolithotomy (PNL) has been considered as the first-line choice for the management of >20mm kidney stones. Microchannel percutaneous nephrolithotomy (Mini PCNL) which takes nephrolithotomy channel size less than…
- Trial name
- NCT03206515
- Testing
- 18F Peel-Way Sheath, 18F access sheath with a suction-evacuation function
- Where
- China
- Volunteers
- 86 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Calculi, Ureteral Obstruction
Assessment of Drug-eluting Ureteral Stent on Bacterial Adherence and Biofilm Formation
The purpose of this study is to determine the clinical effects of a triclosan stent on adherent bacteria, stent biofilms, and patient urine cultures in patients with an indwelling triclosan ureteral stent.
- Trial name
- NCT00250406
- Testing
- Ureteral Stent
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Stone, Oxidative Stress
Lime Powder Regimen in Healthy Volunteers
The study aims to investigate the pharmacokinetic parameters and its antioxidative effects in Thai healthy men.
- Trial name
- LimePKphase1 (NCT01273025)
- Testing
- Lime powder regime
- Where
- Thailand
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Urolithiasis, Urinary Lithiasis
Impact of Renal Anatomy on Shock Wave Lithotripsy Outcomes for Lower Pole Kidney Stones
Kidney stone disease affects almost 10% of overall population, often requiring a surgical intervention. Currently, shock wave lithotripsy is considered a first-line treatment option for patients suffering from symptomatic kidney…
- Conditions
- Urolithiasis, Urinary Lithiasis, Kidney Calculi
- Trial name
- NCT01589484
- Testing
- SWL - Compact Delta Dornier Med Tech
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- University of Sao Paulo
Kidney Stone
SEARCH FOR OPTIMAL ANAESTHESIA IN RETROGRADE INTRARENAL SURGERY
Patients undergoing retrograde intrarenal surgery for kidney stones from November 2017 to May 2018 were prospectively recruited to participate in the study.
- Trial name
- NCT03999255
- Testing
- combined respiratory support (CRS)
- Where
- Russia
- Volunteers
- 38 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Kidney Calculi, Urinary Tract Infections
Is it Necessary for Patients With a Positive Urine Culture to Achieve a Negative Result After Antimicrobial Treatment Before Undergoing Percutaneous Nephrolithotomy?
Objective: The current European Association of Urology (EAU) guidelines do not provide clear recommendations on whether patients with a positive urine culture(UC) should wait until the culture turns negative following…
- Conditions
- Kidney Calculi, Urinary Tract Infections, Sepsis
- Trial name
- NCT06210425
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Junhao Zheng
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Stone, Kidney
Clinical Efficacy of Mini-PCNLversus RIRS for the Management of Upper Urinary Tract Calculus (1-2.5 cm)
The goal of this [ type of study:]prospective randomized clinical trial. The main question is to compare the outcomes of mini-percutaneous nephrolithotomy (m-PCNL) and retrograde intrarenal surgery (RIRS) in treating upper…
- Trial name
- NCT06031103
- Testing
- mini-PCNL procedure, RIRS procedure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Kidney Calculi, Radiation Exposure
Safety and Efficacy of Fluoroscopy-free Technique During Retrograde Intrarenal Surgery for Renal Stones
Aiming to reduce radiation exposure to patients and physicians, the investigators conduct this study protocol to evaluate the possibility of performing retrograde intrarenal surgery (RIRS) under direct visualization without…
- Conditions
- Kidney Calculi, Radiation Exposure, Retrograde Intrarenal Surgery
- Trial name
- NCT05269108
- Testing
- Fluoroscopy-free RIRS, Standard RIRS
- Where
- Egypt
- Volunteers
- 503 people
- Sponsor
- Al-Azhar University
Kidney Calculi, Urolithiasis
Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS
Retrograde intrarenal surgery (RIRS) is a widely used treatment for kidney stones; however, postoperative infectious complications remain a significant concern.
- Conditions
- Kidney Calculi, Urolithiasis, Urinary Tract Infections
- Trial name
- NCT07655050
- Testing
- Standard Retrograde Intrarenal Surgery, Gentamicin Irrigation, Suction-Enabled Ureteral Access Sheath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Hitit University
Renal Calculi
Diagnostic Accuracy of x Ray Kub in Diagnosing Renal Calculi Keeping CT Scan as Gold Standard
In clinical practice both Xray and CT Scan KUB are reliable,however, Ctscan is superior to X ray KUB in detecting renal and ureteric calculi,the reson being stone that are missed by xray KUB are usually small and sould pass…
- Trial name
- NCT06767384
- Testing
- X-ray
- Where
- Pakistan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Superior University
Secondary Hyperoxaluria, Nephrolithiasis
A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria
Identify individuals with greater absorption of oxalate based on increase in urinary oxalate excretion in response to a controlled oxalate-rich test meal.
- Conditions
- Secondary Hyperoxaluria, Nephrolithiasis, Hyperoxaluria, Kidney Stones
- Trial name
- NCT03095885
- Testing
- Test Meal
- Where
- 5 sites in United States
- Volunteers
- 22 people
- Sponsor
- Allena Pharmaceuticals
Prostate Cancer, Benign Prostatic Hypertrophy
Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones.
This is a double-blind, study to evaluate the performance of NV-VPAC1 PCa Urine Diagnostic Test in three distinct populations being treated at the Intermountain Urology Clinic.
- Conditions
- Prostate Cancer, Benign Prostatic Hypertrophy, Bladder Stones, Kidney Stones
- Trial name
- VPAC (NCT03630926)
- Testing
- NV-VPAC1 PCa Urine Diagnostic Test
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Intermountain Health Care, Inc.
Kidney Calculi, Calcium Oxalate Kidney Stones
Evaluating the Vitamin K2 Status of Calcium-based Stone Formers
This is an observation, single site-study with one study visit during which all data and samples will be collected. Study participants will be asked to provide blood, urine, and fecal samples so that the investigators may study…
- Conditions
- Kidney Calculi, Calcium Oxalate Kidney Stones, Vitamin K 2, Human
- Trial name
- NCT05081960
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Stones, Ureteral Stones
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
To determine if emergency department patients with acute ureteral colic pain due to a ureteral stone who are treated with tamsulosin, versus placebo, will experience a shorter time to passage of their stone or resolution of their…
- Trial name
- NCT00448123
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Robert Swor
Kidney Stones
Surgical Outcomes and Costs in Using the Shenzhen HugeMed 6.3 French Flexible Ureteroscope
Comprehensive comparative investigations between HugeMed HU30M 6.3 Fr f-URS and traditional approach f-URS devices in RIRS are lacking in an American population.
- Trial name
- NCT07296835
- Testing
- Ureteroscopy using the 6.3 Fr f-URS hugemed, Hugemed 6.3 Fr f-URS
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Kansas Medical Center
Kidney Stone Prevention
Protein Sources Urinary Stone Risk
Prior studies have shown that the source of dietary protein can have a significant impact on urinary stone risk. However, whey and plant protein isolates have not been compared.
- Trial name
- NCT05460247
- Testing
- Protein
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Kidney Stones, Tumor
The Impact of Ureteral Stents on Peristalsis
The purpose of the study is to investigate the impact of ureteral stents on the functioning of ureteral peristalsis (normal contractions in the ureteral organ muscle).
- Conditions
- Kidney Stones, Tumor, Hydronephrosis
- Trial name
- NCT01739738
- Testing
- Ureteral Stent
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Ureteral Calculi
Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
This randomized controlled trial compares the efficacy and safety of four treatment strategies for ureteral stone expulsion: Mirabegron alone, Tamsulosin alone, a combination of both, and standard conservative care.
- Trial name
- NCT07310797
- Testing
- Mirabegron, Tamsulosin
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation