Clinical trials: Urination Disorders
Urinary Incontinence, Balance
Effect of Pelvic Floor Muscle Training on Balance and Fall Risk in Females With Urinary Incontinence
Understanding the relationship between Pelvic floor muscle dysfunctions as stress urinary incontinence with Postural balance ability and subsequent fall risk in postmenopausal females is important in terms of injury prevention…
- Trial name
- NCT06738147
- Testing
- pelvic floor muscle training, balance exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Lower Urinary Tract Symptoms, Urinary Incontinence
Turkish Validation and Reliability of LURN SI-29 Questionnaire in Patients With Lower Urinary Tract Symptoms
Lower urinary tract symptoms is quite frequent in men and women. To better understand the the symptoms that characterize lower urinary tract, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has…
- Trial name
- NCT04722458
- Testing
- Lower Urinary Tract Dysfunction Research Network Symptom Index-29 (LURN SI-29), IPSS, UDI-6
- Where
- Turkey (Türkiye)
- Volunteers
- 290 people
- Sponsor
- Istanbul Medeniyet University
Stress Urinary Incontinence, Mixed Urinary Incontinence
Comparing Use of a Digital Health System of Pelvic Floor Exercise Program to Kegel Exercises in Stress Urinary Incontinence
A randomized controlled trial for patients with stress urinary incontinence or stress-dominant mixed incontinence. Subjects will be randomized to 8-weeks of home kegel exercises or 8 weeks of pelvic floor muscle exercises using…
- Trial name
- NCT03632447
- Testing
- Leva, PFDx
- Where
- 7 sites in United States
- Volunteers
- 77 people
- Sponsor
- Renovia, Inc.
Urinary Stress Incontinence
One Year Outcome Using the Ajust System for Treatment of Urinary Stress Incontinence
During the last decade numerous new procedures have been presented regarding surgical treatment of urinary stress incontinence (1,2).
- Trial name
- NCT01754558
- Testing
- Ajust system, TVT/TVT-O
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Zealand University Hospital
Urinary Incontinence
Efficacy of Prompted Voiding Therapy in Elderly Hospitalized.
This study evaluates effectiveness to apply prompted voiding in urinary incontinence and dependence patients admitted at functional recovery ward in a mid-stay hospital.
- Trial name
- NCT04117126
- Testing
- Prompted voiding
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Guadarrama Hospital
Type 2 Diabetes Mellitus, CKD and Albuminuria
A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKD
The purpose of this clinical research study is to determine whether dapagliflozin alone or in combination with saxagliptin can decrease albuminuria and improve glycemic control in patients with Type 2 diabetes, albuminuria and…
- Trial name
- NCT02547935
- Testing
- Dapagliflozin 10 mg, Saxagliptin 2.5 mg
- Where
- 112 sites in United States, Australia and 7 more
- Volunteers
- 459 people
- Sponsor
- AstraZeneca
IgA Nephropathy
A Study of JADE101 in Participants With Immunoglobulin A Nephropathy
This open-label Phase 2 study will characterize the safety and efficacy of JADE101 in participants with IgA nephropathy, and the results will contribute to the overall clinical characterization of JADE101 in this patient…
- Trial name
- NCT07541287
- Testing
- JADE101
- Where
- 20 sites in United States, Australia and 3 more
- Volunteers
- 30 people
- Sponsor
- Jade Biosciences, Inc.
Prostate Cancer, Erectile Dysfunction
Pentafecta Outcomes After Robot-assisted Laparoscopic Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy (RALRP) is a surgical technique for the treatment of prostate cancer. The aim of this study was to report our initial experience with RALRP, by applying the concept of pentafecta.
- Conditions
- Prostate Cancer, Erectile Dysfunction, Complication of Surgical Procedure, Urinary Incontinence
- Trial name
- NCT03706508
- Testing
- Robot-assisted laparoscopic radical prostatectomy
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Multiple Sclerosis, Urinary Incontinence
Effects of Spinal Stabilization on the Pelvic Floor in Women With Multiple Sclerosis
The purpose of this study was to investigate the effects of spinal stabilization exercises focusing on the pelvic floor on core stability, urinary symptoms and pelvic floor muscle function in women with Multiple Sclerosis and…
- Conditions
- Multiple Sclerosis, Urinary Incontinence, Lower Urinary Tract Symptoms
- Trial name
- NCT07074587
- Testing
- Pelvic floor muscle exercises, Spinal stabilization exercises focusing on the pelvic floor + Pelvic floor muscle exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Abant Izzet Baysal University
Stress Urinary Incontinence
Efficacy of Mini Sling Versus Transobturator Tape in Surgical Management of Women With Stress Urinary Incontinence
To compare the efficacy of mini sling against Transobturator tape for surgical management of women with stress urinary incontinence.
- Trial name
- NCT06334848
- Testing
- transobturator tape
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Kidney Disease
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases
Three kidney diseases that affect both children and adults are minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS) and membranous nephropathy (MN).
- Trial name
- NCT02639260
- Testing
- N-acetyl D-mannosamine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Maturity-Onset Diabetes of the Young, Type 3, Type 2 Diabetes
Impact of SGLT2 on Glucosuria in HNF1A-MODY
Maturity onset diabetes of the young (MODY) is a subtype of diabetes which is caused by mutations in specific genes leading to diabetes.
- Trial name
- MOD3ST-CLAMP (NCT05417646)
- Testing
- Hyperglycaemic clamp, Empagliflozin
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Steno Diabetes Center Copenhagen
Multiple Sclerosis
Study of Behavioral Modification Program and Mirabegron to Improve Urinary Urgency in Multiple Sclerosis
The purpose of this study is to determine if treatment with Mirabegron will improve urinary urgency control beyond that achieved with pelvic floor exercises alone
- Trial name
- MIRROR (NCT02086188)
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Theodore R. Brown, MD MPH
Urinary Incontinence
Effects of Pilates Exercises Versus Pelvic Floor Muscle Exercises Among Elderly Women With Urinary Incontinence
To compare the effects of Pilates exercises versus pelvic floor muscle exercises among elderly women with urinary incontinence. The study is a single-blinded randomized clinical trial.
- Trial name
- NCT05341778
- Testing
- Shoulder bridge, Clam shell, Scissors
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Benign Prostate Hyperplasia, Urinary Retention
Prostatic Artery Embolization Versus 532 nm Green Light PVP for Catheterized Patients
The primary objective is to assess whether prostatic artery embolization has a similar efficacy and safety profile as GreenLight PVP in treating patients with urinary retention secondary to benign prostate hyperplasia (BPH).
- Trial name
- NCT02006303
- Testing
- Green light PVP, Prostatic artery embolization
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- Royal Victoria Hospital, Canada
Stress Urinary Incontinence
TVTO™ X TVTS ™ for Treatment of Stress Urinary Incontinence
This is a prospective, comparative randomized controled trial. The general purposes of this study is to compare the efficacy and safety of TVTO™ and TVTSecur™ as surgical treatment for female urinary stress incontinence.
- Trial name
- TVTOxTVTS (NCT01095159)
- Testing
- TVT-O, TVT-S
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Federal University of São Paulo
Pelvic Floor Disorders, Anxiety
Enhancing Behavioral Treatment for Women With Pelvic Floor Disorders
The purpose of this proposal is to test a novel behavioral treatment - Unified Protocol Cognitive-Behavior Therapy (UP-CBT)1 - to enhance quality of life in women with pelvic floor disorders.
- Conditions
- Pelvic Floor Disorders, Anxiety, Urinary Urgency, Urinary Incontinence
- Trial name
- NCT03623880
- Testing
- Unified Protocol, Supportive Therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Prostate Cancer, Urinary Incontinence
Augmented BLAdder NecK rEconstruction Trial for Improved Urinary Function After Radical Prostatectomy
The investigators are conducting a prospective, randomized trial to investigate whether patients randomized to receive an augmented bladder neck reconstruction (aBNR) at the time of robotic-assisted laparoscopic prostatectomy…
- Conditions
- Prostate Cancer, Urinary Incontinence, Surgery
- Trial name
- BLANKET (NCT04305379)
- Testing
- Augmented Bladder Neck Reconstruction, Standard Bladder Neck Reconstruction
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Johns Hopkins University
Cervical Carcinoma, Endometrial Carcinoma
Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy
This clinical trial studies how well and how easy it is to use a device called Flyte in improving problems with bladder control (urinary incontinence) among endometrial and cervical cancer survivors who have undergone radiation…
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Overactive Bladder, Voiding Disorders
- Trial name
- NCT07662824
- Testing
- Educational Intervention, Interview, Flyte Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Mayo Clinic
Urinary Incontinence
Comparison Between Pelvic Muscle Training and Pilates Exercises for UI in Postmenopausal Women
Introduction: Urinary incontinence (UI) is a condition that affects around 40% of postmenopausal women and is therefore considered a public health problem.
- Trial name
- NCT05446792
- Testing
- PFMT, PE
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana