Clinical trials: Urination Disorders
Urinary Retention
Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery
Post-operative urinary retention (POUR) is a frequent complication reported as ranging from 10 to 55% in the literature. In a recent retrospective study from Laliberte et al in Quebec City, we observed that 19% of the patients…
- Trial name
- TEMPOUR (NCT03314025)
- Testing
- Tamsulosin Hydrochloride 0.4 MG, Foley catheter
- Where
- 3 sites in Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Breast Cancer, Urine
Investigation of Urinary Biomarkers for the Detection of Breast Cancer
The aim of this study is to investigate and possibly validate urinary biomarkers for breast cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these…
- Conditions
- Breast Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP3 (NCT05453591)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Novosanis NV
Neurogenic Urinary Bladder Disorder, Urinary Bladder, Neurogenic
Efficacy and Tolerability of Propiverine Hydrochloride in Patients With Neurogenic Detrusor Overactivity
The purpose of this clinical study is to compare efficacy and safety of propiverine hydrochloride extended and immediate release formulations in patients suffering from neurogenic detrusor overactivity.
- Conditions
- Neurogenic Urinary Bladder Disorder, Urinary Bladder, Neurogenic, Bladder Disorder, Neurogenic, Urinary Bladder Disorder, Neurogenic
- Trial name
- NCT01530620
- Testing
- Propiverine hydrochloride ER (extended release), Propiverine hydrochloride IR (immediate release)
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- APOGEPHA Arzneimittel GmbH
Stress Urinary Incontinence, Urinary Incontinence
Combined Non-ablative Er:YAG Laser and Magnetic Stimulation for Treatment of Female Urinary Incontinence
This single-arm pilot study aims to investigate the efficacy and safety of a combined non-ablative Erbium:Yttrium-Aluminium-Garnet (Er:YAG) laser and High Intensity Tesla magnetic Stimulation (HITS) treatment for female urinary…
- Trial name
- NCT06559423
- Testing
- non-ablative Er:YAG laser and high intensity Tesla magnetic stimulation (HITS)
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- Zdravstveni Zavod Štrumbelj
Stress Urinary Incontinence
Randomised Controlled Trial Comparing Tension-Free Vaginal Tape (TVT), Pelvicol & Autologous Slings for Stress Urinary Incontinence(SUI)
The purpose of this trial was to discover which type of operation for stress urinary incontinence in women offered better results: autologous slings, TVT or Pelvicol slings.
- Trial name
- NCT01057550
- Testing
- Autologous fascial sling, TVT, Pelvicol
- Where
- United Kingdom
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Abertawe Bro Morgannwg University NHS Trust
Urinary Incontinence, Stress
Perineal Ultrasound in Men Before and After Radical Prostatectomy
Prospective study to evaluate a new technique. Comparison of perineal sonography in men before and after radical prostatectomy and in incontinent men after radical prostatectomy before and after operative treatment with male…
- Trial name
- NCT03037008
- Testing
- Perineal Sonography
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Kantonsspital Winterthur KSW
Vaginal Prolapse
Anterior Vaginal Wall Reconstruction
The purpose of this study is to assess the effectiveness of the polypropylene tape in preventing cystocele recurrence when placed underneath the bladder base as a concomitant measure to the anterior colporrhaphy procedure.
- Trial name
- NCT00571350
- Testing
- tvt-o operation, tvt o operation
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Hippocration General Hospital
Stress Urinary Incontinence
Concurrent Surgery for Prolapse and Stress Urinary Incontinence to Reduce Further Surgery for Incontinence
Urinary incontinence is a common and distressing medical condition which affects 26% of women in developing countries.Globally upto 54% women suffer from pelvic organ prolapse and stress urinary incontinence concomitantly.Women…
- Trial name
- NCT06521450
- Testing
- anti incontinence surgery
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Kidney Disease, Albuminuria
Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and Albuminuria
Patients with chronic kidney disease (CKD) and albuminuria are at increased risk of developing cardiovascular disease (CVD) which is often associated with hypertension, left ventricular hypertrophy, endothelial dysfunction and…
- Trial name
- NCT00625820
- Testing
- 6R BH4, Vitamin C
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
Urinary Incontinence, Stress, Urinary Incontinence, Urge
French Study to Evaluate the Impact of a Cognitive Therapy on Urinary Incontinent Women of All Age's Perineal Settings.
This trial is a pathophysiological study evaluating the impact of a cognitive therapy on the perineal neuromuscular mechanisms in women patients with urinary incontinence.
- Trial name
- NCT03797365
- Testing
- Classical rehabilitation, Cognitive associated rehabilitation
- Volunteers
- 40 people
- Sponsor
- Pierre and Marie Curie University
Stress Urinary Incontinence (SUI)
Effects of Diaphragmatic Breathing With Kegal Exercises on Pelvic Floor Muscle Function and Quality of Life Among Multigravida Women With Stress Incontinence
The goal of this clinical trial is to determine the effect of diaphragmatic breathing with kegel exercises on pelvic floor muscle function and quality of life among multigravida women with stress urinary incontinence The main…
- Trial name
- NCT07537309
- Testing
- Diaphragmatic Breathing, Kegel exercises
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Mixed Incontinence, Urge and Stress
Mixed Urinary Incontinence Symptoms Before and After Treatment With Botox and Bulkamid
This study compares mixed urinary incontinence symptoms before and after a combined treatment with Botox and Bulkamid. Eligible for the study are adult females with a mixed urinary incontinence, having both urgency urinary…
- Trial name
- NCT02815046
- Testing
- Botulinum toxin type A, Polyacrylamide hydrogel
- Where
- Switzerland
- Volunteers
- 58 people
- Sponsor
- Prof. Dr. Volker Viereck
Bladder Cancer
Screening for Bladder Cancer
In the study proposed, up to 1,500 men age 60 and over with strong smoking histories will test their urine for the presence of blood daily for two 10-day testing periods with the Ames Hemastix.
- Trial name
- NCT00848627
- Testing
- Specimen and questionnaires only
- Where
- 3 sites in United States, Canada
- Volunteers
- 197 people
- Sponsor
- Baylor College of Medicine
Chronic Low-back Pain (cLBP), Urinary Incontinence (UI)
Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence
Urinary incontinence (UI), Chronic low back pain (CLBP) in women are prevalent and often coexist. Multiple conditions when coexist, it leads to reduced Quality of life in turn causing physical and mental impairment.
- Conditions
- Chronic Low-back Pain (cLBP), Urinary Incontinence (UI), Pelvic External Myofascial Mobilisation, Myofascial Techniques
- Trial name
- NCT07351851
- Testing
- PEMM with Theragun, Active Comparator: Control
- Where
- Qatar
- Volunteers
- 200 people
- Sponsor
- Hamad Medical Corporation
BPH (Benign Prostatic Hyperplasia), Incontinence, Urinary
Evaluation of the Impact of Preoperative Pelvic Floor Exercise on Incontinence After Laser Enucleation of the Prostate: a Feasibility Study.
The purpose of this study is to assess the acceptability and feasibility of including a pelvic floor muscle exercise program into the care provided to patients undergoing prostate enucleation, studying both patients and…
- Conditions
- BPH (Benign Prostatic Hyperplasia), Incontinence, Urinary, HoLEP, Pelvic Floor Muscle Exercise
- Trial name
- PPP (NCT07456345)
- Testing
- Pelvic Floor Muscle Exercise before and after surgery
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Urinary Incontinence
Outcomes of Urinary Incontinence Treatment in Primary Care: APP Co-Management and Electronic Consult
The burden of urinary incontinence (UI) on American women is immense in both human and financial terms, and continues to rise with the aging US population.
- Trial name
- OUTPACE (NCT06040645)
- Testing
- APP Co-management, E-consult
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Chronic Kidney Diseases
Propolis Effects in Patients With Chronic Kidney Disease
The aim of this study is to determine the impact of Propolis on proteinuria reduction and protection of the glomerular filtration rate in chronic renal failure patients.
- Trial name
- NCT02766036
- Testing
- Propolis
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Urinary Retention, Lower Motor Neurone Lesion
Electroacupuncture of Different Treatment Frequency in Chronic Urinary Retention Caused by Lower Motor Neuron Lesions
The aim of this study is to compare the effects of electroacupuncture of different frequency in patients with chronic urinary retention caused by lower motor neuron lesions
- Trial name
- NCT06354244
- Testing
- Electroacupuncture of 2 sessions per week, Electroacupuncture of 3 sessions per week, Electroacupuncture of 4 sessions per week
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Urinary Incontinence (UI), Urinary Stress Incontinence
Usability, Acceptability and Effect of a Mobile Application and Connected Object for Older Women With UI
This project aims to evaluate the usability, acceptability, and impact of the Oups! mobile app and a connected Bluetooth dynamometer for at-home PFM training to treat UI. The study will: 1.
- Conditions
- Urinary Incontinence (UI), Urinary Stress Incontinence, Telehealth
- Trial name
- OUPS (NCT07427693)
- Testing
- Physiotherapy through mobile app and connected device
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Stress Urinary Incontinence
Study of Macroplastique Safety and Effectiveness in the Treatment of Female Stress Urinary Incontinence
The ROSE Registry will determine the long-term safety and effectiveness of Macroplastique in the treatment of female stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD).
- Trial name
- ROSE (NCT01115465)
- Testing
- Macroplastique
- Where
- 19 sites in United States
- Volunteers
- 276 people
- Sponsor
- Uroplasty, Inc