Clinical trials: Urogenital
Placenta Accreta Spectrum
Role of Uterotonics in Reducing Intraoperative Blood Loss in Patients With PASD Undergoing Cesarean Hysterectomy
Objectives: To evaluate the effect of oxytocin in reducing intraoperative blood loss in patients with PAS disorders planned for cesarean hysterectomy.
- Trial name
- NCT06493968
- Testing
- oxytocin
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Kidney Diseases
Sirolimus for Massive Polycystic Liver
The purpose of this study is to evaluate the effectiveness and safety of Sirolimus in reducing liver volume in autosomal dominant polycystic kidney disease.
- Trial name
- SILVER (NCT01680250)
- Testing
- Sirolimus
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Endometrial Cancer
Combination Chemotherapy With or Without G-CSF in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003691
- Testing
- filgrastim, cisplatin, doxorubicin hydrochloride
- Where
- 73 sites in United States, Canada
- Volunteers
- 240 people
- Sponsor
- Gynecologic Oncology Group
Prostate Cancer
Study Evaluating the Correlation Between C-11 Acetate Uptake and Retention as Measured by PET and FAS in Prostate Cancer
The purpose of this study is to understand if a new type of radiology test called positron emission tomography (PET) with carbon 11 acetate will help us to understand which cancers produce more of a protein called fatty acid…
- Trial name
- NCT00139191
- Testing
- C-11 acetate PET scan
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Feeding Intolerance, Necrotizing Enterocolitis
Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy
Nowadays feeding intolerance (FI) is a common condition among preterm infants. It has been estimated that 16%-29% of premature infants admitted to neonatal intensive care units (NICUs) develop feeding intolerance at some point…
- Conditions
- Feeding Intolerance, Necrotizing Enterocolitis, Premature Infant
- Trial name
- NIRS/NICU2 (NCT02534090)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Prolapse, Urinary Incontinence
What is the Prevalence of Female Pelvic Floor Disorders in Minnesota?
To determine the prevalence of pelvic organ prolapse and urinary incontinence among women in Minnesota using a short web-based self-administered questionnaire.
- Conditions
- Prolapse, Urinary Incontinence, Fecal Incontinence, Bladder Pain Syndrome
- Trial name
- NCT03536221
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Urinary Tract Infections, Catheter Infection
Noble Meta Alloy Coated Catheters in Patients With Long Term Catheterization
Eighty percent of nosocomial UTI caused by indwelling urinary catheters and so known-as catheter-associated UTI. CAUTI leads to multiple local and systemic derangements such as suprapubic pain, dysuria, cystitis, pyelonephritis…
- Conditions
- Urinary Tract Infections, Catheter Infection, Catheter-Related Infections, Infection
- Trial name
- NCT04825314
- Testing
- Urethral catheter
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Chronic Kidney Diseases, Type 2 Diabetes Mellitus
Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa
Chronic kidney disease (CKD) is associated with increased cardiovascular morbidity and mortality. The prevalence of CKD is increasing worldwide and is assumed to also dramatically increase in Sub-Saharan Africa (SSA).
- Conditions
- Chronic Kidney Diseases, Type 2 Diabetes Mellitus, Arterial Hypertension, Obesity
- Trial name
- RenalTWO (NCT05881447)
- Where
- Tanzania
- Volunteers
- 1,200 people
- Sponsor
- Swiss Tropical & Public Health Institute
Postpartum Disorder
The Effect of Back Massage Applied to Mothers in the Early Postpartum Period on Parameters
In the literature, there are separate studies on massage, comfort, anxiety, and physiological parameters for massage practice, but there are no studies that measure the physiological parameters of comfort, pain, anxiety, blood…
- Trial name
- NCT06200649
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Non-muscular Invasive Bladder Cancer
Clinical Study to Investigate the Safety and Tolerance of Therapeutic BCG in Postoperative Adjuvant Therapy in Subjects With Moderate to High-risk Non-muscular Invasive Bladder Cancer (NMIBC)
Phase I clinical study to investigate the safety and tolerance of therapeutic BCG in postoperative adjuvant therapy in subjects with moderate to high-risk non-muscular invasive bladder cancer (NMIBC)
- Trial name
- NCT06350838
- Testing
- BCG for Therapeutic Use
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chengdu CoenBiotech Co., Ltd
HIV-infection/Aids
The Effectiveness of a Mobile Interactive Supervised Therapy (MIST) Intervention for Improving Adherence to HIV Medication
A total of 40 HIV infected patients will be randomly assigned into intervention or control group. Participants in the intervention group will use an smart phone application for two months.
- Trial name
- NCT03794648
- Testing
- Mobile Interactive Supervised Therapy (MIST)
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Intrauterine Synechiae, Tissue Adhesion, Surgery-Induced
The Efficacy and Safety of Medicurtain® in Patients With Hysteroscopy (Pivotal Study)
This study was designed to assess the safety and efficacy of MEDICURTAIN, an adhesion barrier in patients who underwent hysteroscopy with uterine polyp or endometrial myoma or missed abortion (uterine lesion suspected to be…
- Trial name
- NCT04638855
- Testing
- Medicurtain®
- Where
- South Korea
- Volunteers
- 223 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Acute Kidney Injury
Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI
The purpose of the present study is to determine if remote ischemic preconditioning reduces incidence of acute kidney injury in patients with reduced kidney function undergoing Percutaneous Coronary Intervention.
- Trial name
- EUROCRIPS (NCT02195726)
- Testing
- Remote ischemic preconditioning
- Where
- 7 sites in France, Italy and 1 more
- Volunteers
- 1,110 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Adult Nocturnal Enuresis, Urinary Incontinence (UI)
This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.
This post-market study will assess the performance of and user experience with the PureWick™ System in a home setting. The study will also observe safety of the study device and collect information from participants about their…
- Trial name
- PUREST (NCT06666426)
- Testing
- PureWick System, Hollister Female Urinary Pouch External Collection Device
- Where
- 15 sites in United States
- Volunteers
- 171 people
- Sponsor
- C. R. Bard
Pregnancy, Gestational Diabetes
Fructosamines and Gestational Diabetes (FRUCTO)
The prevalence of gestational diabetes is estimated at between 2 and 6%, but can be much higher in specific populations. The specific treatment of gestational diabetes (diet, control weight gain, self monitoring glucose , insulin…
- Trial name
- FRUCTO (NCT02159378)
- Testing
- Fructosamines
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Preterm Birth
Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length
A randomized clinical trial comparing vaginal progestogen and vaginal pessary as an intervention for twin pregnancies with short cervical length.
- Trial name
- NCT04342585
- Testing
- Micronised vaginal progesterone, Vaginal pessary
- Where
- Malaysia
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Renal Insufficiency
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems
This study is open to people with and without kidney problems. People can join the study if they are 18 years or older and have a body mass index (BMI) between 18.5 and 35 kg/m2.
- Trial name
- NCT05718843
- Testing
- BI 425809
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Syphilis
Serological Response to Retreatment of Serofast Early Syphilis Cases With Benzathine Penicillin
A continuing challenge to determining the response to treatment of early syphilis (primary, secondary, early latent syphilis) is exemplified by the substantial proportion of patients who fail to achieve serological cure and…
- Trial name
- NCT02884115
- Testing
- benzathine penicillin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Urinary Incontinence
Muscle Progenitor Cell Therapy for Urinary Incontinence
This study is designed to evaluate the safety of muscle progenitor cells (MPCs) for the treatment of urinary incontinence due to incompetent outlet (bladder neck/urethra).
- Trial name
- MPC (NCT01953315)
- Testing
- Autologous Muscle Progenitor Cells
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University
Surgery, Immune System and Related Disorders
Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery
Over 30 million surgeries are performed annually in the US. Up to 30% of surgical patients experience delayed surgical recovery, marked by prolonged post-surgical pain, opioid consumption, and functional impairment, which…
- Conditions
- Surgery, Immune System and Related Disorders, Preoperative Care, Gastrointestinal Disease
- Trial name
- NCT04498208
- Testing
- Physical Prehabilitation, Stress Reduction Prehabilitation, Cognitive Prehabilitation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Stanford University
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