Clinical trials: Urogenital
Multicystic Dysplastic Kidney, Polycystic Kidney Disease
Amnioinfusion for Fetal Renal Failure
The goal of this clinical trial is to learn if serial amnioinfusions can improve the chances of survival for fetuses with severe kidney problems that cause low amniotic fluid (anhydramnios).
- Conditions
- Multicystic Dysplastic Kidney, Polycystic Kidney Disease, Fetal Renal Anomaly, Anhydramnios
- Trial name
- NCT06728228
- Testing
- Amnioinfusion
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Fetal Care Center, PLLC
Shock, Septic, Renal Failure, Acute
Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care)
Sepsis and septic shock are still important causes of mortality in intensive care medicine. Renal replacement therapy by standard volume haemofiltration is currently used, but a higher-volume haemofiltration may improve the…
- Trial name
- IVOIRE (NCT00241228)
- Testing
- Venovenous haemofiltration (renal replacement therapy)
- Where
- 16 sites in Belgium, France and 1 more
- Volunteers
- 139 people
- Sponsor
- University Hospital, Bordeaux
Ovarian Cancer
Adjuvant Chemotherapy of Three-step Regimen in Ovarian Cancer
Ovarian cancer was mostly diagnosed at late stage (III/IV) with high rate of recurrence after first line of therapy by optimal cytoreductive sugery and 6-8cycle of TP chemotherapy.
- Trial name
- ACTS (NCT02562365)
- Testing
- Etoposide, Cyclophosphamide, Carboplatin
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Xiaohua Wu MD
Acute Kidney Injury
Effects of Oral Protein Load on Kidney Function in Patients Undergoing Cardiac Surgery
Acute kidney injury (AKI) occurs in approximately one-third of patients undergoing cardiac surgery (CS), and represents one of the most significant negative predictors of patient outcome in this population.
- Trial name
- NCT03102541
- Testing
- None intervention
- Volunteers
- 214 people
- Sponsor
- University of Giessen
Iron Deficiency Anaemia
Time to Relapse of Iron Deficiency Anaemia After Standard Treatment With The Intravenous Iron (Monofer®)
The objective is to monitor and quality assure the efficacy, including effects on quality of life, and safety of Monofer® in Chronic Kidney Disease and Inflammatory Bowel Disease patient populations when Monofer® is used…
- Trial name
- NCT02546154
- Testing
- 10% Iron Isomaltoside 1000
- Where
- United Kingdom
- Volunteers
- 359 people
- Sponsor
- Pharmacosmos UK Ltd
Benign Renal Tumors, Malignant Renal Tumors
First-in-Human Safety Study Of Laser Tissue Welding For Surtureless Laparoscopic Partial Nephrectomy
The objective of this pilot study will be to obtain a clinical safety and efficacy endpoint profile of laser tissue welding therapy for sealing the resected kidney surface after laparoscopic partial nephrectomy required for…
- Trial name
- LTW-KIDNEY (NCT02061605)
- Testing
- Laser Tissue Welding Device
- Where
- United States
- Sponsor
- Laser Tissue Welding, Inc.
Chronic Kidney Disease
Correlation of Urinary Kallikrein With Cytokines, Proteinuria and Renal Function in Chronic Renal Disease Patients
Urinary kallikrein excretion is known to increase in patients with nephrotic syndrome and sick cell disease, but decrease in patients with chronic kidney disease or uremia.
- Trial name
- NCT00395005
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Human Papillomavirus Infection
Comparison of Self-collection Using Dry Compared to Wet Swabs for HPV Detection
This study will compare the performance of self-collected vaginal swabs, transported without liquid media (dry swabs) and self-collected vaginal swabs, transported in liquid media (wet swabs) for detection of hrHPV DNA LBC as the…
- Trial name
- HPV (NCT06213051)
- Testing
- • COPAN Self-collection FLOQSwabs® (COPAN, Italy)
- Where
- Kenya
- Volunteers
- 1,306 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Urine VOCs From DKD and Nephrotic Syndrome Pateints
The Biosensor Using the Target Urine VOCs for Detecting DKD Diabetic Kidney Disease
Volatile organic compounds (VOCs) are easily evaporated substances produced by pathophysiologic metabolism and have been utilized in research as potential new biomarkers for differentiating various diseases, acting as the odor…
- Trial name
- VOCs in DKD (NCT07137351)
- Testing
- The Biosensor Using the Target Urine Volatile Organic Compounds
- Where
- Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- Suranaree University of Technology
Advanced/Recurrent Breast Cancer, Endometrial Cancer
A Study of Combination of Temsirolimus (Torisel®) and Pegylated Liposomal Doxorubicin (PLD, Doxil®/Caelyx®) in Advanced or Recurrent Breast, Endometrial and Ovarian Cancer
A study to examine the combination of temsirolimus and Caelyx® (chemotherapeutic) in advanced or recurrent breast, endometrial and ovarian cancer.
- Conditions
- Advanced/Recurrent Breast Cancer, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT00982631
- Testing
- Temsirolimus/PLD
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
HIV Infections
A Simplified Kaletra® (Lopinavir/Ritonavir)-Based Therapy Versus a Sustiva® (Efavirenz)-Based Standard of Care in Previously Non-Treated HIV-Infected Subjects
The purpose of this study is to determine whether a simplified lopinavir-ritonavir based therapy will continue to keep the viral load to very low levels after initial treatment with a combination of Kaletra® (lopinavir/ritonavir)…
- Trial name
- NCT00075231
- Testing
- Kaletra® (lopinavir/ritonavir), Combivir® (lamivudine, zidovudine), Sustiva® (efavirenz)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Abbott
Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer
Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers
This study has 2 parts: Phase 1A and Phase 1B. The primary objectives of Phase 1A are to evaluate the safety of KITE-439 and to determine a recommended Phase 1B dose.
- Trial name
- NCT03912831
- Testing
- KITE-439, Cyclophosphamide, Fludarabine
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- Gilead Sciences
Fallopian Tube Cancer, Ovarian Cancer
Study Comparing Tumor Debulking Surgery Versus Chemotherapy Alone in Recurrent Platinum-Sensitive Ovarian Cancer
It is still not clear whether a positive AGO-score just selects patients with less aggressive biologic tumor behavior who as well would have had a positive outcome by chemotherapy only, or , if it is a score selecting patients…
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer
- Trial name
- DESKTOPIII (NCT01166737)
- Testing
- Tumor Debulking Surgery (surgery in recurrent ovarian disease)
- Where
- 86 sites in Austria, Belgium and 10 more
- Volunteers
- 408 people
- Sponsor
- AGO Study Group
Fertility Issues, Blastocyst IVF
A Multicenter Prospective Randomized Controlled Clinical Trial Comparing Constant (5%) Versus Sequential (5%-2%) Oxygen Concentration Embryo Culture Protocols in Assisted Reproductive Technology
To evaluate whether there were significant differences in the effects of constant (5%) versus sequential (5%-2%) oxygen concentration protocols in embryo culture on term live birth rates.
- Conditions
- Fertility Issues, Blastocyst IVF, Embryo Culture
- Trial name
- NCT07050537
- Testing
- Constant oxygen concentration protocols in embryo culture, Sequential oxygen concentration protocols in embryo culture
- Where
- 6 sites in China
- Volunteers
- 980 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Polycystic Ovary Syndrome
A Cooking and Eating Study
Background. The polycystic ovary syndrome (PCOS) is a complex hormonal disorder that presents in susceptible girls around the time of menarche. Females with PCOS have high levels of androgens (e.g., testosterone).
- Trial name
- ACES (NCT01079845)
- Testing
- Nutrition Education, Dietary Counseling, and Cooking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Development and Validation of Gut Permeability Sensor, Permeability; Increased
Fluorescence Spectroscopy for Gut Permeability Assessment
This research aims to develop portable devices - known as fluorescence spectrometers - to monitor the leakage of fluorescent dyes out of the gut into the blood stream.
- Conditions
- Development and Validation of Gut Permeability Sensor, Permeability; Increased, Celiac Disease, Inflammatory Bowel Diseases
- Trial name
- GutPerm (NCT03434639)
- Testing
- Spectroscopic gut permeability test
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Ureteral Calculi
Medical Expulsive Therapy of Single Distal Ureteral Stones
Current therapeutic options for ureteral stones include active intervention as well as conservative "watch and wait" approaches.
- Trial name
- NCT00831701
- Testing
- Tamsulosin
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
End-Stage Renal Disease, Hemodialysis Complication
The Effect of Intradialytic Exercise on Postural Abnormalities
This randomized, assessor-blinded controlled trial will evaluate the preliminary efficacy and safety of a 12-week supervised intradialytic multimodal exercise program for improving postural abnormalities in adults receiving…
- Trial name
- NCT07720401
- Testing
- Supervised Intradialytic Multimodal Exercise Program
- Where
- Iran
- Volunteers
- 98 people
- Sponsor
- Pardis Specialized Wellness Institute
Congestive Heart Failure, Renal Dysfunction
Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction
The purpose of the study is to show that low dose recombinant BNP coupled with phosphodiesterase V inhibition will improve renal dysfunction and promote relief of volume overload in patinets with acute decompensated heart failure…
- Trial name
- BNP+PDEVI (NCT00818701)
- Testing
- low dose Nesiritide, nesiritide, Sildenafil
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
HIV Infection
A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)
The purpose of this study is to evaluate the safety and tolerability of DOR/ISL in adult participants with HIV-1 who had been previously treated with DOR/ISL in earlier clinical studies.
- Trial name
- NCT05766501
- Testing
- DOR/ISL
- Where
- 95 sites in United States, Argentina and 13 more
- Volunteers
- 641 people
- Sponsor
- Merck Sharp & Dohme LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.