Clinical trials: Urogenital Prolapse
Pelvic Organ Prolapse, Prolapse
A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability
There is a strong need for a better, simplified and informative applicable classification system that should be used to speak a common descriptive language among health care providers that treat POP.
- Conditions
- Pelvic Organ Prolapse, Prolapse, Prolapse, Vaginal, Prolapse Uterus
- Trial name
- NCT06520722
- Testing
- Prolapse scoring system
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Rectocele, Enterocele
A Study Evaluating the Clinical Outcome of a Modified d'Hoore Technique for Laparoscopic Ventral Mesh Rectopexy
The purpose of this observational study is to evaluate the clinical outcome of a modified d'Hoore technique for laparoscopic ventral mesh rectopexy in patients with primary rectal prolapse, rectocele and/or enterocele.The goal of…
- Conditions
- Rectocele, Enterocele, Rectal Prolapse
- Trial name
- POP-01 (NCT04564677)
- Testing
- Ifabond (Péters surgical)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Duomed
Urinary Tract Infection, Pelvic Organ Prolapse
L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.
This study will include women who will undergo pelvic reconstructive surgery and/or anti-incontinence sling procedures. Patients will be randomized to the combination of L-methionine, Hibiscus Sabdariffa and Boswellia Leaf…
- Conditions
- Urinary Tract Infection, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- NCT02216253
- Testing
- L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele
Cystocele, Pelvic Organ Prolapse
Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexisting Stress Urinary Incontinence: A Retrospective Case Series.
The objective of the study is to retrospectively collect the data on patients who underwent pelvic organ prolapse treatment using a non-ablative Er:YAG laser with SMOOTH mode and to conduct an objective evaluation of safety and…
- Conditions
- Cystocele, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- NCT04417413
- Testing
- Fotona ProlapLase
- Where
- Serbia
- Volunteers
- 41 people
- Sponsor
- Aleksandra Novakov Mikic
Colonic Neoplasms, Rectal Neoplasms
NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery
After resection of diseased segments of the large intestine, the continuity of the intestine has to be restored. This can be done by suturing or with so called stapling devices.
- Conditions
- Colonic Neoplasms, Rectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases
- Trial name
- NCT01056913
- Testing
- Compression Anastomosis Device, follow-up colonoscopy
- Volunteers
- 62 people
- Sponsor
- St John of God Hospital, Vienna
Pelvic Organ Prolapse, Urinary Incontinence
One Year Outcome After Robotic Assisted Laparoscopic Sacral Colpopexy, a Case Series Review
Robotic approach to sacral colpopexy is a relatively new procedure. The literature is scarce in regard to its long-term outcomes. This advanced procedure is offered at MMH through the Urogynecology division.
- Trial name
- NCT01055860
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Guided IMagery and Patient Satisfaction (GIMPS) Following Urogynecological Surgery
We hypothesize that women who use GIM pre-operatively will feel more prepared for surgery, have less anxiety on the day of surgery and have higher satisfaction scores 6 weeks after surgery compared to women who undergo our…
- Trial name
- GIMPS (NCT02165280)
- Testing
- Guided IMagery (GIM)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loyola University
Uterine Prolapse
Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy
This research protocol is a randomized controlled trial. It is being done to compare and find out the relative differences between the materials, (Pelivisoft) "natural organic mesh" to poly propylene mesh (Pelvitex) "manmade…
- Trial name
- NCT00564083
- Testing
- sacral colpopexy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Prolapse
Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)
1.0 STUDY OBJECTIVE 1.1 PRIMARY OBJECTIVE - To compare two methods of polypropylene mesh attachment during laparoscopic sacrocolpopexy (LSC): running technique using self-anchoring 1 barbed delayed absorbable suture (Quill™ SRS…
- Trial name
- QUILL-LSC (NCT01551992)
- Testing
- Quill suture vs. Interrupted suture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Pelvic Floor Prolapse, Functional Constipation
Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse
This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse
- Conditions
- Pelvic Floor Prolapse, Functional Constipation, Rectocele
- Trial name
- NCT04547816
- Testing
- Biofeedback therapy, Tibial neuromodulation, Pelvic floor muscles training
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Federal State Budgetary Scientific Institution
Vaginal Vault Prolapse
Laparoscopic Versus Vaginal Approach Closure Complications
Hysterectomy is considered as a common operation in Gynecology. Hysterectomy could be made by vaginally, laparoscopically or abdominally.
- Trial name
- NCT05960292
- Testing
- Laparoscopic and Vaginal Hysterectomy
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Egymedicalpedia
Post-operative Dyspareunia
Dilators for Dyspareunia Prevention
This is a randomized clinical trial comparing rates of de novo dyspareunia in women with and without vaginal dilator use following surgery for pelvic organ prolapse with traditional posterior repair.
- Trial name
- DDS (NCT01299363)
- Testing
- Dilator use
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Pelvic Organ Prolapse
Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse
Evaluation of the anatomical and functional results of laparoscopic sacrohysteropexy and sacrocolpopexy surgeries performed without using mesh in the surgical treatment of pelvic organ prolapse
- Trial name
- NCT06176521
- Testing
- Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pelvic Organ Prolapse
Evaluation of the Avaulta Procedure for the Correction of Pelvic Organ Prolapse - Results at 1 Year
This study is a 1 year review of all patients who had surgery to correct pelvic organ prolapse (i.e. cystocele, rectocele, enterocele) using the Avaulta synthetic mesh kit.
- Trial name
- NCT00774215
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse, Stress Urinary Incontinence
Impact of Decision Aids in Urogynecology
To evaluate how patient knowledge and confidence in decision making can be impacted by shared decision making in common urogynecology conditions.
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Overactive Bladder
- Trial name
- NCT04369404
- Testing
- Pelvic organ prolapse decision aid, Stress urinary incontinence decision aid, Overactive bladder decision aid
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP)
Accelerometer Measured Early Recovery After Prolapse Surgery
The AccelERate study will evaluate the physical recovery of patients who have undergone Pelvic Organ Prolapse (POP) surgery. This will be evaluated via a self-reported recovery questionnaire completed daily.
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Patient Education
- Trial name
- AccelERate (NCT07218016)
- Testing
- Postoperative Exercise regimen
- Where
- 7 sites in United States
- Volunteers
- 288 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Urogenital Prolapse
LAparoscopic Preventive PRErectal Mesh
Urogenital prolapse is a frequent and invalidating pathology in women, involving the anterior vaginal wall and the uterus in most cases. Posterior vaginal wall prolapse is present in only 50% of cases.
- Trial name
- LAPREM (NCT03766048)
- Testing
- Single-Anterior-Mesh, SAM, Double-Mesh, DM
- Where
- 9 sites in France
- Volunteers
- 834 people
- Sponsor
- University Hospital, Lille
Pelvic Organ Prolapse
Pelvic Floor Repair Systems for Prolapse Repair
1. This is a prospective, multi-center, post market study, which will be conducted under a common protocol. 2. The primary objective of the study is to evaluate long-term efficacy of the AMS Pelvic Floor Repair System devices for…
- Trial name
- PROPEL (NCT00638235)
- Testing
- AMS Apogee™ with IntePro, AMS Apogee™ with Intexen LP, AMS Perigee™ with IntePro
- Where
- 28 sites in United States, Belgium and 5 more
- Volunteers
- 725 people
- Sponsor
- ASTORA Women's Health
Pelvic Organ Prolapse
Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse
Comparing FDA-approved DermaPure with patient's own native tissue surgically for diagnosis of pelvic organ prolapse.
- Trial name
- NCT03939715
- Testing
- DermaPure®, native tissue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colorado Pelvic Floor Consultants