Clinical trials: Urologic Diseases
Renal Insufficiency
Dalteparin's Influence on Renally Compromised: Anti-Ten-A Study (DIRECT)
The investigators' primary research objective is: To determine the safety of dalteparin prophylaxis, 5,000 IU once-daily, in Intensive Care Unit (ICU) patients based on: the proportion of patients with trough anti-Xa > 0.40 IU/mL…
- Trial name
- NCT00138099
- Testing
- Fragmin (dalteparin sodium)
- Where
- 14 sites in Canada
- Volunteers
- 140 people
- Sponsor
- Hamilton Health Sciences Corporation
Lower Urinary Tract Symptoms
A Pilot Study to Assess Effects of Self-Administered Nitrous Oxide (SANO) on Urodynamic Study (UDS) Parameters
A urodynamic study (UDS) is a common procedure done to learn more about the cause of urinary symptoms. For some patients, UDS can be associated with anxiety or discomfort.
- Trial name
- NCT05883332
- Testing
- Self-Administered Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer, Colorectal Cancer
SU006668 in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs such as SU006668 may stop the growth of solid tumors by stopping blood flow to the tumor. PURPOSE: Phase I trial to study the effectiveness of SU006668 in treating patients who have advanced solid tumors.
- Conditions
- Breast Cancer, Colorectal Cancer, Gastric Cancer, Kidney Cancer
- Trial name
- NCT00024063
- Testing
- orantinib
- Sponsor
- Jonsson Comprehensive Cancer Center
Kidney Disease
Optimizing Linezolid Dosing in Patients With Advanced Renal Impairment: a Therapeutic Drug Monitoring-based Evaluation
The goal of this clinical trial is to adjust the Linezolid dose according to its blood level in adults with kidney diseases. It will also learn about the safety of linezolid.
- Trial name
- NCT07138521
- Testing
- Linezolid (IV and PO)
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Liver Cirrhosis, Renal Failure
Rifaximin Versus Lactulose in Renal Failure
The purpose of this study is to evaluate patients with cirrhosis of the liver and renal failure and determine if the administration of rifaximin as compared to lactulose is associated with less frequent and/or slower progression…
- Trial name
- NCT00748904
- Testing
- Rifaximin, Lactulose
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Urinary Incontinence, Diabetes
Urinary Incontinence and Endocrine Factors. A Part of Lolland-Falster Health Study (LOFUS).
Previous studies have shown an increase in the prevalence of urgency and urgency incontinence in women with diabetes. Regarding the condition urinary stress incontinence, the literature is diverted.
- Conditions
- Urinary Incontinence, Diabetes, Thyroid Diseases
- Trial name
- EFUI (NCT04279184)
- Where
- Denmark
- Volunteers
- 6,000 people
- Sponsor
- Nykøbing Falster County Hospital
End Stage Renal Disease, Catheter Infection
AUSTrian Randomized Interventional Study on Dialysis Accesses
Patients with diagnosed end stage renal disease and indication for chronic dialysis rely on a well-functioning access for dialysis.
- Conditions
- End Stage Renal Disease, Catheter Infection, Shunt Malfunction
- Trial name
- AUSTRIA (NCT03764358)
- Testing
- Arteriovenous Fistula, Tunneled Cuffed Catheter
- Where
- Austria
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna
Hypertension, Hypertension Resistant to Conventional Therapy
High Prevalence of Secondary Arterial Hypertension (HIPRESH) with Prospective Systematic Screening in a Cohort of Consecutive Hypertensive Patients Referring to Regional Specialized Center
Hypertensive Patients referring to our center will undergo a systematic diagnostic workup aimed at finding the cause(s) of their high blood pressure.
- Conditions
- Hypertension, Hypertension Resistant to Conventional Therapy, Secondary Hypertension to Endocrine Disorders, Secondary Hypertension
- Trial name
- HIPRESH (NCT06664255)
- Volunteers
- 1,400 people
- Sponsor
- University Hospital Padova
Secondary Hyperparathyroidism
Observational Program of Zemplar in Patients With End Stage Chronic Kidney Disease and Parathyroid Disorder on Hemodialysis in the Russian Federation
Eighty-six eligible participants with secondary hyperparathyroidism will be enrolled at thirteen sites in Russia. Planned therapy will be six months.
- Trial name
- NCT01401478
- Where
- 13 sites in Russia
- Volunteers
- 86 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Hemorrhagic Cystitis
A Pilot Study Using Placenta Derived Decidual Stromal Cells for Hemorrhagic Cystitis
The purpose of this study is to evaluate the safety and efficacy using placenta derived decidual stromal cell therapy for hemorrhagic cystitis after allogeneic hematopoietic cell transplantation.
- Trial name
- NCT02172963
- Testing
- Decidual Stromal Cell therapy
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Nephrotic Syndrome in Children, Minimal Change Disease
taVNS for FRNS in Children
Children with frequently relapsing nephrotic syndrome (FRNS) are exposed to prolonged courses of steroids and other immunosuppressant medications.
- Conditions
- Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
- Trial name
- kidNEY-VNS (NCT05588063)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma
Pembrolizumab and Axitinib as Neoadjuvant Therapy for Locally Advanced Non-metastatic Clear Cell Renal Cell Carcinoma
This is a single-arm phase II clinical trial to evaluate the initial efficacy and safety of pembrolizumab combined with axitinib as neoadjuvant therapy for locally advanced non-metastatic clear cell renal cell carcinoma.
- Trial name
- PANDORA (NCT04995016)
- Testing
- Pembrolizumab, Axitinib
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Tianjin Medical University Second Hospital
Urolithiasis, Renal Stones
The Predictors of Successful Oral Dissolution Therapy in Radiolucent Renal Stones; A Prospective Evaluation
The aim of the study is to evaluate the predictors of success of oral dissolution therapy in radiolucent renal stones in a large series of patients from a tertiary referral center in order to define the optimum case scenarios…
- Trial name
- NCT02373384
- Testing
- Oral alkalinization (Potassium citrate, Allopurinol), Life style modification, Dietary recommendations (decrease purine rich diet as red meat and fish, increase vegetables)
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- Mansoura University
Focal Segmental Glomerulosclerosis
Safety and Effectiveness of Propagermanium in Focal Segmental Glomerulosclerosis Participants Receiving Irbesartan
This study will be evaluating the safety and efficacy of propagermanium for the treatment of participants with FSGS who are already taking irbesartan by: monitoring symptoms that participants may experience while on the study…
- Trial name
- ACTION (NCT03649152)
- Testing
- Propagermanium
- Where
- 11 sites in Australia
- Volunteers
- 8 people
- Sponsor
- Dimerix Bioscience Pty Ltd
Heart Failure, Acute Kidney Injury
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
The overall objective of this study is to determine whether the addition of SGLT2 inhibitors to usual care in hospitalized patients with heart failure associated acute kidney injury is safe and efficacious.
- Trial name
- NCT07273838
- Testing
- Dapagliflozin 10mg Tab
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
Renal Cell Carcinoma
Stereotactic Body Radiotherapy (SBRT) and Sorafenib in Patients With Metastatic, Recurrent, or Unresectable Renal Cell Cancer (RCC)
The purpose of this study is to determine the safety and efficacy of combined stereotactic body radiotherapy (SBRT) + sorafenib in the treatment of patients with Stage IV renal cell carcinoma (RCC) who have recurred locally…
- Trial name
- NCT00672178
- Testing
- Stereotactic body radiation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Duke University
Kidney Diseases, Obesity
Epidemiologic Data of Patients in a Teaching Hospital
This small cross-sectional epidemiological study is designed to evaluate the prevalence of the following parameters in hospitalized patients in a tertiary teaching hospital (medical department only): kidney insufficiency obesity…
- Trial name
- NCT00114335
- Where
- Switzerland
- Volunteers
- 352 people
- Sponsor
- Luzerner Kantonsspital
Primary Hyperoxaluria
Primary Hyperoxaluria Mutation Genotyping
This study will help us determine whether certain genetic mutations, more than others, are a cause of more severe disease in Primary Hyperoxaluria.
- Trial name
- NCT00589225
- Testing
- Genetic Analysis
- Where
- United States
- Volunteers
- 902 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cancer of Kidney and Renal Pelvis, Cancer of Liver
Effects of Dexmedetomidine During Radiofrequency Ablation of Abdominal Tumours
The purpose of he study is to evaluate effects of dexmedetomidine on pain during radiofrequency ablation of liver and kidney tumours.
- Trial name
- NCT02016391
- Testing
- Dexmedetomidine
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala University Hospital
Acute Kidney Injury, Hypothermia
Hypothermia Risk With Continuous Renal Replacement Therapy
The present study aims at testing if the TherMax blood warmer is more accurate and reliable in reaching and maintaining chosen target temperature during continuous renal replacement therapy as compared to the Prismaflo IIS blood…
- Trial name
- HR-CRRT (NCT03973814)
- Testing
- Thermax Blood Warmer
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska University Hospital
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