Clinical trials: Urologic Diseases
Lupus Nephritis
Efficacy of Lower Dose Prednisolone in the Induction of Remission of Lupus Nephritis
The LN is a common cause of mortality and morbidity in SLE. The use of high-dose glucocorticoids (GC) with an immunosuppressive agent is usual practice for treating this condition.
- Trial name
- LN (NCT04146220)
- Testing
- Prednisolone
- Where
- Bangladesh
- Volunteers
- 32 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Clear Cell Renal Cell Carcinoma
Diagnostic Imaging for Clear Cell Renal Cell Carcinoma
The main objective is to study whether imaging detection of the biomarker DAT can be used to detect kidney tumors identified by computer tomography (CT), which are pathologically assesses as being of the clear cell subtype.
- Trial name
- RCCSCAN (NCT03185182)
- Testing
- Ioflupane I123
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Region Skane
Cardiovascular Diseases, Hypertension
Uppsala Self-Screening of Cardiovascular Health
U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can…
- Conditions
- Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus
- Trial name
- U-SCREEN (NCT07614659)
- Testing
- Home-based multimodal cardiovascular screening
- Where
- Sweden
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Johan Sundström
Septic Shock, Acute Kidney Injury
Renin and Renal Biomarker Response to Angiotensin II
Septic shock continues to exert a large economic burden around the world. Several developments have occurred that lead to the current study.
- Trial name
- NCT04558359
- Testing
- Standard of Care, Angiotensin II
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alexander Flannery
Urinary Incontinence
The Effect Of Pelvic Floor Muscle Training With Biofeedback And Extracorporeal Magnetic Innervation On The Urinary Symptoms, Sexual Function And Quality Of Life
The effect of Pelvic Floor Muscle Training with Biofeedback and Extracorporeal Magnetic Innervation on the Urinary Symptoms, Sexual Function and Quality of Life of Women with Stress Urinary Incontinence
- Trial name
- NCT03875196
- Testing
- Pelvic Floor Muscle Training With Biofeedback, Extracorporeal Magnetic Innervation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ege University
Recurrent Renal Cell Cancer, Renal Cell Carcinoma
Bevacizumab With or Without MEDI-522 in Treating Patients With Unresectable or Metastatic Kidney Cancer
This phase I/randomized phase II trial is studying the side effects and best dose of bevacizumab and to see how well it works when given together with or without MEDI-522 in treating patients with unresectable or metastatic…
- Conditions
- Recurrent Renal Cell Cancer, Renal Cell Carcinoma, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer
- Trial name
- NCT00684996
- Testing
- etaracizumab, bevacizumab
- Where
- 5 sites in United States
- Volunteers
- 5 people
- Sponsor
- National Cancer Institute (NCI)
Overactive Bladder, Neurogenic Detrusor Overactivity
Study Of Fesoterodine In Pediatric Overactive Bladder Patients Aged 8-17 Years
The purpose of the study is to evaluate the pharmacokinetics, safety, and tolerability of fesoterodine following administration to pediatric patients, aged 8-17 years, with overactive bladder.
- Trial name
- NCT00857896
- Testing
- Fesoterodine
- Where
- 9 sites in United States
- Volunteers
- 21 people
- Sponsor
- Pfizer
Overactive Bladder
A Pilot Study Evaluating the Usability of the Oabi Mobile Application
Our primary purpose is to assess the use feasibility and acceptability of the study phone app called, "Oabi" app with patients diagnosed with overactive bladder disorder (OAB).
- Trial name
- OAB (NCT04534946)
- Testing
- This is not an intervention study
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Kidney Function Issue, Acute Kidney Injury
N-Acetylcysteine Roles in Preserving Renal Function Measured by Urinary KIM-1 (Kidney Injury Molecule-1) and Serum Creatinine on Cancer Patients With Cisplatin Based Chemotherapy: A Randomized Placebo-Controlled Trial
The goal of this clinical trial is to learn if N-Acetylcysteine drug works to protect kidney function in adults patient with cancer.
- Conditions
- Kidney Function Issue, Acute Kidney Injury, Cancer (Solid Tumors), Kidney Function Tests
- Trial name
- NCT07156786
- Testing
- N-acetylcysteine (NAC)
- Volunteers
- 72 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Urinary Tract Infections, Urinary Tract; Accessory
Reduction of Catheter-associated Urinary Tract Infection With a Daily Nursing Review of the Indication
The purpose of this study is to determine whether the daily nurse review of the indication of the urinary catheter compared to the everyday care of the working staff is effective to reduce the rate of catheter-associated urinary…
- Trial name
- NCT01067768
- Testing
- Daily review
- Where
- Colombia
- Volunteers
- 1,209 people
- Sponsor
- Hospital Pablo Tobón Uribe
Overactive Bladder
Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation
The aim of this study is to determine the efficacy of an accelerated course for percutaneous tibial nerve stimulation (PTNS) induction to treat overactive bladder symptoms.
- Trial name
- NCT03547518
- Testing
- PTNS treatment
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Corewell Health East
Cardiogenic Shock, Cardiorenal Syndrome
Levosimendan Infusion in Critically Ill Patients With Cardiogenic Shock
To determine whether Levosimendan infusion in patients with cardiogenic shock and cardiorenal syndrome refractory to standard inotropic therapy, improves hemodynamics and renal function, whilst being safe.
- Conditions
- Cardiogenic Shock, Cardiorenal Syndrome, Acute Kidney Failure
- Trial name
- NCT04917497
- Testing
- Levosimendan
- Volunteers
- 43 people
- Sponsor
- University of Zurich
Urinary Incontinence
Assessment of Two Postoperative Techniques Used to Predict Voiding Efficiency After Gynecologic Surgery
After gynecologic surgery, it may be difficult to void (urinate). This problem is usually short-term with normal function returning within a few days to a few weeks.
- Trial name
- NCT00392210
- Testing
- Voiding Trial
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Rochester
End-Stage Renal Disease
Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial
The SPin-D Trial is a phase II randomized, double-blind, placebo-controlled, multi-center study of spironolactone (SPL) for patients with hemodialysis-dependent end-stage renal disease.
- Trial name
- SPin-D (NCT02285920)
- Testing
- Spironolactone
- Where
- 4 sites in United States
- Volunteers
- 129 people
- Sponsor
- University of Pennsylvania
Haemodialysis Complication, Major Adverse Cardiac Events
Novel Cardiovascular Biomarkers in Patients With Kidney Disease
Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should. End-stage kidney failure (ESKD) is the final, irreparable stage of chronic kidney disease (CKD), where kidney function…
- Trial name
- CBKD (NCT06037759)
- Testing
- Cardiac Biomarkers, Lipidomics, Proteomics
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Urinary Incontinence
Comparison of Surgical Procedures to Reduce Urinary Stress Incontinence
The primary aim of this clinical trial is to compare the treatment success for two surgical procedures that are frequently used and have similar cure rates, yet have not been compared directly to each other in a large, rigorously…
- Trial name
- SISTEr (NCT00064662)
- Testing
- Burch Modified Tanagho, Autologous Fascia Sling
- Where
- 9 sites in United States
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Renal Cell Cancer
Percutaneous Tumor Ablation Vs Partial Nephrectomy for Small Renal Mass: the Impact of Histologic Variant and Tumor Size
The aim, of this study is to investigate recurrence rates in patients with T1 renal cell carcinoma (RCC) undergone partial nephrectomy (PN), radiofrequency ablation (RFA) or cryoablation (Cryo).
- Trial name
- CRYO-BO-2021 (NCT06829888)
- Volunteers
- 955 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bladder Cancer
Autophagy Bladder Cancer
Bladder cancer is the most common malignancy of the urinary tract. It represents the 7th most commonly diagnosed cancer in male population worldwide and drops to the 11th when both genders are considered .
- Trial name
- NCT03254888
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Carcinoma, Renal Cell
Capecitabine and Interferon-Alpha in Metastatic Renal Cell Carcinoma Patients With Failure on Interleukin-2 Based Regimens
The aim of this study is to determine preliminary efficacy of capecitabine and interferon-alpha in second-line after interleukin-2 based regimens in patients with MRCC
- Trial name
- NCT00591188
- Testing
- capecitabine, interferon-alpha
- Where
- Russia
- Volunteers
- 49 people
- Sponsor
- Kidney Cancer Research Bureau
Clear Cell Renal Cell Carcinoma, VHL Syndrome
Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer
The goal of this study is to comprehensively map intra and inter tumor heterogeneity of ccRCC in VHL patients through the use of imaging, molecular biology and genomics techniques.
- Trial name
- ITHORinVHL (NCT06195150)
- Testing
- Blood collection
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- IRCCS San Raffaele
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