Clinical trials: Urologic Diseases
Atrial Fibrillation, Atrial Flutter
Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis 2 (SAFE-D2)
People receiving dialysis are more likely to develop atrial fibrillation (AF), an irregular heartbeat that increases the risk of stroke.
- Conditions
- Atrial Fibrillation, Atrial Flutter, End Stage Kidney Disease (ESRD), Dialysis Patients
- Trial name
- SAFE-D2 (NCT07779746)
- Testing
- Eliquis, No oral anticoagulation
- Volunteers
- 848 people
- Sponsor
- Unity Health Toronto
Renal Cancer
Interferon Alpha-2b (Intron A) for Metastatic or Unresectable Clear Cell Renal Carcinoma
This study will determine the response rate of daily low dose interferon-alpha-2b in patients with metastatic or unresectable clear cell renal cell carcinoma.
- Trial name
- NCT00293527
- Testing
- Interferon Alpha-2b
- Sponsor
- Ohio State University Comprehensive Cancer Center
Metastatic/Advanced Renal Cell Carcinoma
Evaluation Of The Impact Of A Call Center In Management Of Metastatic And/Or Advanced Renal Cell Carcinoma Patients Treated With Sunitinib (Sutent) In First Line
100 patients with metastatic and/or advanced renal cell carcinoma treated with sunitinib (Sutent) will be inclued and followed with standard care plus a call center Principal assumption : the proportion of patients presenting…
- Trial name
- RENACALL (NCT02187042)
- Testing
- Best supportive care, call center
- Where
- 13 sites in France
- Volunteers
- 70 people
- Sponsor
- Pfizer
Renal Scan in Suspected Obstructive Uropathy in Adult Hydronephrotic Patient
Influence of Diuresis Timing (F+0 Vs F-15) on 99m Tc DTPA Renography for the Diagnosis of Suspected Obstructive Uropathy
Evaluation of the influence of the diuretic injection timing (F+0 Vs F-15) on the dynamic 99mTc- DTPA renal scintigraphy for the diagnosis of suspected obstructive uropathy in adult hydronephrotic patients.
- Trial name
- NCT04564469
- Testing
- Furosemide
- Volunteers
- 50 people
- Sponsor
- Assiut University
Lupus Nephritis
Long-Acting Tacrolimus for the Treatment of Resistant Lupus Nephritis
Glomerulonephritis is one of the major disease manifestations of systemic lupus erythematosus (SLE). Around one-third of the patients, however, do not respond to conventional immunosuppressive therapy, and they have a high risk…
- Trial name
- NCT01206569
- Testing
- Long-acting tacrolimus (Advagraf, Astellas Pharma)
- Where
- Hong Kong
- Volunteers
- 2 people
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer, Urinary Incontinence
A Prospective Evaluation of Early Acupuncture for Immediate Continence Enhancement After Prostatectomy
This study is being done to see if early acupuncture treatment can help men control their urination better right after their urinary catheter is removed following prostate cancer surgery (radical prostatectomy).
- Trial name
- PEACE (NCT07239518)
- Testing
- Electroacupuncture
- Volunteers
- 144 people
- Sponsor
- Bin Xu
Bladder Cancer
Detecting CREPT in Urine for Bladder Cancer Diagnosis and Monitoring
This study will, for the first time, establish a non-invasive diagnostic model for bladder cancer based on CREPT expression levels in exfoliated urothelial cells using a multicenter cohort, and validate its value in the…
- Trial name
- NCT07514897
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Carcinoma, Renal Cell, Kidney Disease
Safety and Toxicity Study of Sorafenib in Patients With Kidney Cancer
Determine time-to-progression (TTP) for an escalating dose schedule for subjects with progressive metastatic renal cell carcinoma treated with sorafenib
- Conditions
- Carcinoma, Renal Cell, Kidney Disease, Kidney Cancer
- Trial name
- NCT00854620
- Testing
- Sorafenib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Kidney Disease, Chronic
A Study to Test BI 764198 in People With a Type of Kidney Disease Called Focal Segmental Glomerulosclerosis
This study is open to adults with a type of kidney disease called focal segmental glomerulosclerosis (FSGS). The purpose of this study is to find out whether a medicine called BI 764198 improves the health of the kidneys in…
- Trial name
- NCT05213624
- Testing
- BI 764198
- Where
- 54 sites in United States, Australia and 8 more
- Volunteers
- 67 people
- Sponsor
- Boehringer Ingelheim
Sarcoma, Neuroblastoma
A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors
Background: Pazopanib, a drug that inhibits the growth of new blood vessels in tumors, was recently approved by the Food and Drug Administration to treat advanced kidney cancer in adults.
- Conditions
- Sarcoma, Neuroblastoma, Wilms Tumor, Osteosarcoma
- Trial name
- NCT01130623
- Testing
- Pazopanib (GW786034)
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Ureteral Calculi
The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic
This is a single institution, prospective study to evaluate the prognostic significance of renal and bladder ultrasound with ureteral jet assessment and its utility to evaluate the spontaneous stone passage rate of ureteral…
- Trial name
- NCT02577146
- Testing
- renal and bladder ultrasound with ureteral jet assessment
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Acute Kidney Injury
Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury
This is a single center, randomized, single-blind, placebo-controlled study to evaluate the safety and biochemical effects of niacinamide on metabolic parameters of the kidney in patients undergoing cardiac surgery.
- Trial name
- NCT02701127
- Testing
- Oral niacinamide, 1 gram daily, Oral niacinamide, 3 gram daily
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Beth Israel Deaconess Medical Center
Overactive Bladder
Foot/Hand Neuromodulation for Overactive Bladder (OAB)
The purpose of this study is to determine if electrical stimulation of the foot is effective in the treatment of overactive bladder conditions.
- Trial name
- FootStim (NCT01972061)
- Testing
- Foot stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Christopher J Chermansky, MD
Urinary Tract Infections, Stent Related Infection
Multicentric Study on Infections of the Urinary Tract After Stent Removal (MINUS-trial).
The MINUS-trial is a multicentric prospective observational study in which consecutive patients, 18 years of age and older who receive a ureteral stent during any endoscopic procedure will be approached to participate.
- Trial name
- MINUS (NCT05329883)
- Testing
- Double-J stent removal
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Urinary Incontinence, Nocturnal Enuresis
Effectiveness of Multimodal Pelvic Floor Rehabilitation Program in Children With Different Types of Urinary Incontinence
Urinary incontinence is defined by the International Children's Continence Society as involuntary urinary leakage that can be continuous or intermittent in children aged five and over.
- Conditions
- Urinary Incontinence, Nocturnal Enuresis, Daytime Wetting, Pelvic Floor Disorders
- Trial name
- NCT06231394
- Testing
- multimodal pelvic floor rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Damla Korkmaz Dayican
Palliative Care, Renal Failure, End-stage
Effects of a Transitional Palliative Care Model on Patients With End-stage Renal Failure
Primary aim: 1. To compare the effects of customary care and an interventional Home-based Palliative Renal Program (HBPRP) for ESRF patients 2.
- Trial name
- ESRF (NCT02139917)
- Testing
- Transitional community based palliative care
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The Hong Kong Polytechnic University
Cardiac Anaesthesia
Cardiac Anesthesia Registry Including Biosignal Database for Prognostication of Postoperative Renal Outcome
AKI(Acute Kidney Injury) is a common complication after cardiac surgery which is associated with increased mortality and morbidity.
- Trial name
- NCT06581289
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Yonsei University
Social Psychology
Neuropeptides and Social Behavior
It has long been established that interpersonal relationships can have a profound impact on health and well-being. Yet, we are still learning about the complex biological processes that contribute to positive social interactions…
- Trial name
- NCT01680718
- Testing
- Intranasal oxytocin, Intranasal vasopressin
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
End-Stage Renal Disease
Study of HemoCare™ Hemodialysis System for Home Nocturnal Dialysis in Patients With ESRD
This prospective multi-center, open-label, single-arm study intends to gather and evaluate safety data for the nocturnal use of the HemoCare™ Hemodialysis System.
- Trial name
- NCT04087213
- Testing
- HemoCare™ Hemodialysis System
- Where
- 8 sites in United States
- Volunteers
- 36 people
- Sponsor
- Deka Research and Development
Lung Neoplasms, Ovarian Neoplasms
Tariquidar and Docetaxel to Treat Patients With Lung, Ovarian, Renal and Cervical Cancer
The purpose of this study is three-fold: 1) to examine the ability of the experimental drug tariquidar to improve chemotherapy results by blocking a protein (P-glycoprotein) on some cancer cells that acts to pump out cancer…
- Conditions
- Lung Neoplasms, Ovarian Neoplasms, Cervix Neoplasms, Renal Neoplasms
- Trial name
- NCT00069160
- Testing
- docetaxel, tariquidar, 99mTc-sestamibi imaging
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Cancer Institute (NCI)
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