Clinical trials: Urologic Diseases
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention
As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT04407936
- Where
- China
- Volunteers
- 88,938 people
- Sponsor
- Guangdong Provincial People's Hospital
Bladder Cancer, Brain and Central Nervous System Tumors
Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Bladder Cancer, Brain and Central Nervous System Tumors, Breast Cancer, Esophageal Cancer
- Trial name
- NCT00313599
- Testing
- lapatinib, paclitaxel
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
End Stage Renal Disease
Vitamin D, Insulin Resistance and Inflammation in ESRD
The broad goal of this study is to understand the mechanisms by which Vitamin D receptor activation leads to changes in insulin signaling in advanced uremia.
- Trial name
- NCT00656032
- Testing
- paricalcitol, cinacalcet
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University
Bladder Cancer
Endo-GIA Versus Endowrist Stapler in Intracorporeal Urinary Diversion in Robotic Assisted Radical Cystectomy
The study is a randomized clinical trial (RCT) including patients undergoing robotic assisted cystectomy with intracorporeal ileal conduit at four large university hospitals in Denmark.
- Trial name
- EGIAES (NCT03385798)
- Testing
- Endowrist, Endo-GIA
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Jørgen Bjerggaard Jensen
Urinary Bladder, Overactive
A Study to Evaluate Quality of Life in Patients Switched to Solifenacin From Other Antimuscarinics
This is a 12 month non-interventional study with solifenacin succinate, evaluating the effect of solifenacin on quality of life (QoL) of patients previously treated with antimuscarinics (Males and Females with Overactive Bladder…
- Trial name
- VEST (NCT02087098)
- Testing
- Solifenacin
- Where
- 60 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Astellas Pharma Europe B.V.
Urolithiasis, Nephrolithiasis
Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi
The minimally-invasive extracorporeal shockwave lithotripsy (ESWL) procedure is generally considered the best first-line treatment option for most adults and children with nephrolithiasis, especially when the calculi are smaller…
- Conditions
- Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis
- Trial name
- NCT05270421
- Testing
- Furosemide 40 mg, Conventional Treatment
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Shiraz University of Medical Sciences
Diabetic Nephropathies
Colchicine for Diabetic Nephropathy Trial
Forty patients with diabetic nephropathy will be treated with colchicine up to 2 mg, or placebo, for 18 months. A follow up will be performed after 12 additional months.
- Trial name
- CDNT (NCT02442921)
- Testing
- Colchicine
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Metastatic Renal Cell Carcinoma
Phase II Study of Alternating Sunitinib and Temsirolimus
In the past 5 years, treatment for metastatic Renal Cell Carcinoma (mRCC) has focused on agents directed at blocking tumor and vascular growth pathways.
- Trial name
- NCT01517243
- Testing
- Sunitinib, Temsirolimus
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Renal Malignant Tumor
Correlation of Renal Mass Pathologic Grade and Contrast Enhanced Ultrasound (CEUS)
Patients with renal lesions suspicious for renal cell carcinoma (RCC) have a variety of different treatment pathways available to them.
- Trial name
- NCT03821376
- Testing
- Contrast enhanced ultrasound with Lumason
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Neurogenic Bladder
Bilateral Comparison of Unilateral Sacral Neuromodulation Test Stimulation in the Treatment of Neurogenic Bladder
Neurogenic bladder (NB) is a general term for a series of lower urinary tract symptoms and complications caused by bladder and/or urethral dysfunction caused by nervous system lesions.
- Trial name
- NCT07505940
- Testing
- bilateral sacral nerve stimulation (BNS)
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Qilu Hospital of Shandong University
Smoking Cessation
Tobacco Exposure and Influencing Factors of Smoking Cessation Among Chronic Kidney Disease Patients
The purpose of this study is to describe the tobacco exposure and characteristics of patients with Chronic Kidney Disease (CKD) who quit smoking, to identify patients' tobacco-related knowledge, attitude, and practice (KAP) and…
- Trial name
- NCT06303089
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 567 people
- Sponsor
- Sun Yat-sen University
Diabetic Nephropathies
Henagliflozin Delays the Progress of Diabetic Nephropathy Via Regulates Gut-Renal Axis
Diabetic kidney disease (DKD) is a serious complication of diabetes, and it is also the leading cause of end-stage renal disease (ESRD) in the world.
- Trial name
- NCT06031389
- Testing
- Henagliflozin
- Volunteers
- 120 people
- Sponsor
- Qianfoshan Hospital
Bladder Cancer
Gene Expression Profiling in Patients With Invasive Bladder Cancer Receiving Methotrexate, Vinblastine, Doxorubicin, and Cisplatin
RATIONALE: Drugs used in chemotherapy, such as methotrexate, vinblastine, doxorubicin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00516750
- Testing
- cisplatin, doxorubicin hydrochloride, methotrexate
- Where
- 5 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Kyoto University
Chronic Kidney Disease
Evolution of Bone Histomorphometry and Vascular Calcification Before and After Renal Transplantation
A study of the natural history of bone and mineral disease (BMD) in patients with end-stage renal disease before and after kidney transplantation
- Trial name
- NCT01886950
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetes Mellitus, Type 2, Chronic Kidney Disease
Type 2 Diabetes and Associated Factors in Mexico
The goal of this observational cross-sectional multicenter study is to identify clinical, lifestyle, metabolic, inflammatory, and genetic factors associated with glycemic control and complications of Type 2 Diabetes (T2D) in…
- Conditions
- Diabetes Mellitus, Type 2, Chronic Kidney Disease, Diabetic Nephropathy
- Trial name
- NCT07248891
- Testing
- Clinical and Molecular Assessment
- Where
- 3 sites in Mexico
- Volunteers
- 1,000 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
End-Stage Renal Disease
Morbidity, Mortality, Short and Long-term Survival of Hemodialysis End-stage Kidney Disease Patients in Central Tanzania
Background: In the last 2 decades, Tanzania made great improvements in the renal replacement therapy infrastructure and services.
- Trial name
- NCT03988491
- Where
- Tanzania
- Volunteers
- 10,000 people
- Sponsor
- Benjamin Mkapa Hospital
Sickle Cell Disease
Albuminuria Reduction With Renin Angiotensin System Inhibitors in SCA Patients
The prevalence of Sickle Cell Associated Nephropathy (SCAN) is increasing and is a growing concern. Microalbuminuria is detected in the early onset of SCAN.
- Trial name
- RAND (NCT01195818)
- Testing
- RAS Inhibitors
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Insufficiency, Kidney Diseases
Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male Patients
This study is designed to assess the effect of renal impairment on the pharmacokinetics, safety and tolerability of udenafil in subjects with renal impairment compared to healthy subjects.
- Conditions
- Renal Insufficiency, Kidney Diseases, Urologic Diseases
- Trial name
- DA8159_RI_I (NCT01231997)
- Testing
- Udenafil
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Urothelial Cancer, Bladder Cancer
Trial of Lapatinib and Weekly Paclitaxel for Advanced Urothelial Cancer
This study will involve subjects who have advanced urothelial cancer who are platinum refractory (platinum based chemotherapies that are not effective in treating the cancer), and who are over-expressing EGFR and/or HER2, or do…
- Trial name
- NCT01700010
- Testing
- Lapatinib and Paclitaxel
- Where
- United States
- Sponsor
- University of Michigan Rogel Cancer Center
Overactive Bladder
Treatment of REfractory Overactive BLadder With the AXonics Sacral Neuromodulation System (RELAX-OAB)
The RELAX-OAB (Treatment of REfractory Overactive BLadder with the AXonics Sacral Neuromodulation System) is a post-market clinical follow-up (PMCF) study designed to confirm the performance of the Axonics Sacral Neuromodulation…
- Trial name
- RELAX-OAB (NCT02620410)
- Testing
- Axonics Sacral Neuromodulation (SNM) System
- Where
- 6 sites in Belgium, France and 2 more
- Volunteers
- 51 people
- Sponsor
- Axonics, Inc.
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