Clinical trials: Urologic Diseases
Urinary Incontinence
Efficacy of Prompted Voiding Therapy in Elderly Hospitalized.
This study evaluates effectiveness to apply prompted voiding in urinary incontinence and dependence patients admitted at functional recovery ward in a mid-stay hospital.
- Trial name
- NCT04117126
- Testing
- Prompted voiding
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Guadarrama Hospital
High-Risk Non-Muscle-Invasive Bladder Cancer
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
This is a Phase 2, Multi-Arm, Multi-Cohort, Open-Label Study to Evaluate the Safety and Efficacy of Cretostimogene Grenadenorepvec in Participants with High-Risk Non-Muscle-Invasive Bladder Cancer.
- Trial name
- NCT06567743
- Testing
- Cretostimogene Grenadenorepvec
- Where
- 80 sites in United States, Canada
- Volunteers
- 325 people
- Sponsor
- CG Oncology, Inc.
End-stage Renal Disease (ESRD)
Hierarchical Management for Maintenance Hemodialysis Patients
This prospective, randomized controlled trial investigates the effectiveness of a nurse-led, Triangle Hierarchical Management model compared to routine care for patients on maintenance hemodialysis.
- Trial name
- NCT07123168
- Testing
- Triangle Hierarchical Management, routine care
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yanyan Deng
Urinary Incontinence,Stress, Ultrasound
Ultrasound and Pelvic Floor Muscle Training
The objective is to validate the use of ultrasound measurements (urethral mobility, movement of the ano-rectal angle, elastography measurements) in women with urinary incontiennce before and after pelvic floor muscle training…
- Conditions
- Urinary Incontinence,Stress, Ultrasound, Elastography, Contraction; Pelvic
- Trial name
- ERP (NCT04361890)
- Testing
- perineal ultrasound
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Caen
Urinary Calculi
SP TLF Versus Ho:YAG Laser
The investigators aim to compare the performance of the Super Pulse Thulium fiber laser (SP TFL) with that of the standard Holmium: Yttrium-Aluminium-Garnet (Ho:YAG) laser.
- Trial name
- NCT05048706
- Testing
- Laser lithotripsy (SP TLF), Laser lithotripsy (Ho:YAG)
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Carcinoma, Renal Cell
Contrast-enhanced Ultrasound for Follow-up After Radiofrequency Ablation of Kidney Lesions
Radiofrequency ablation (RFA) is an increasingly popular therapy option for treating small kidney cancer, especially for patients who are not ideal candidates for traditional surgery.
- Trial name
- NCT01141816
- Testing
- Contrast-Enhanced Ultrasound
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Non-muscle Invasive Bladder Cancer
Cis-urocanic Acid (Cis-UCA) in Patients With Primary or Recurrent Non-muscle Invasive Bladder Cancer
The purpose of this study is to evaluate safety, tolerability and pharmacokinetics of intravesical cis-urocanic acid in patients with primary or recurrent non-muscle invasive bladder cancer.
- Trial name
- NCT01458847
- Testing
- cis-UCA solution
- Where
- 2 sites in Finland
- Volunteers
- 12 people
- Sponsor
- BioCis Pharma Ltd
Overactive Bladder
Drug Use-Results Survey of Betanis Tablets in Japan
This study is to determine the following information. 1. The occurrence of adverse drug reactions in clinical settings. 2. Factors potentially impacting safety, effectiveness, and other aspects.
- Trial name
- NCT01919047
- Testing
- Betanis
- Where
- 8 sites in Japan
- Volunteers
- 10,711 people
- Sponsor
- Astellas Pharma Inc
Urinary Bladder Neoplasm
Autologous Cellular Immunotherapy in Patients With Metastatic Bladder Urothelial Carcinoma
Autologous cellular immunotherapy is to collect patient's own immune cells and infuse back into the patient's body after culture in vitro that can activate the anti-tumor immune response and achieve the purpose of cancer…
- Trial name
- NCT03389438
- Testing
- autologous Tcm cells immunotherapy
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Beijing Huanxing Cancer Hospital
Bronchitis, Sinusitis
Fluoroquinolone Associated Disability
The purpose of this study is to: 1) describe drug utilization for Fluoroquinolone(FQ), Azithromycin (AZ) and Sulfamethoxazole/Trimethoprim(ST) in the entire Truven MarketScan Commercial Claims and Encounters database (CCAE)…
- Conditions
- Bronchitis, Sinusitis, Urinary Tract Infections
- Trial name
- NCT03535558
- Testing
- Fluoroquinolone (FQ), Azithromycin (AZ), Sulfamethoxazole/Trimethoprim (ST) Fixed Dose Combination
- Where
- United States
- Volunteers
- 239,306 people
- Sponsor
- Janssen Research & Development, LLC
Bladder Cancer, Transitional Cell Carcinoma
Feasibility Evaluation of Magnetic Resonance Imaging and Positron Emission Tomography for Bladder Cancer Diagnosis and Staging
The purpose of this study is to to find out if the MRI and PET scans can truly stage patients with bladder cancer. Both scans use newer ways to find out if your disease has grown beyond the bladder.
- Trial name
- NCT00612326
- Testing
- MRI and PET scanning procedures
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Kidney Stones
Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Management of Renal Stones
This randomized controlled clinical trial evaluated whether furosemide-assisted forced diuresis during flexible ureteroscopy reduced the residual fragment rate and improved stone clearance in patients with renal stones measuring…
- Trial name
- NCT07336485
- Testing
- Furosemide, Standard Care After Flexible Ureteroscopy Without Furosemide
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Pneumonia, Bacterial, Nosocomial Infection
A Study of the Safety and Effectiveness of Doripenem in Filipino Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections
The purpose of this study is to assess the safety and effectiveness of doripenem treatment among Filipino patients with nosocomial pneumonia, complicated intra-abdominal infections, and complicated urinary tract infection.
- Conditions
- Pneumonia, Bacterial, Nosocomial Infection, Intraabdominal Infections, Urinary Tract Infection
- Trial name
- NCT01763008
- Testing
- No intervention
- Where
- 4 sites in Philippines
- Volunteers
- 170 people
- Sponsor
- Janssen Pharmaceutica
End Stage Renal Disease
Rituximab Desensitization Therapy for Patients on the Waiting List for Kidney Transplant
This is a study of patients who have a high risk of kidney rejection before kidney transplant. The hypothesis is that treatment with a medication called rituximab will make it possible for them to receive a kidney transplant from…
- Trial name
- NCT00167791
- Testing
- rituximab
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Carcinoma, Renal Cell, Carcinoma, Urothelial
Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immunotherapy in Genitourinary Malignancies (CTC Immune Based Biomarkers)
This pilot study purpose of this study is to describe peripheral circulating immune cell profiles at baseline and change on treatment with immune checkpoint inhibitors in renal cell carcinoma and urothelial carcinoma.
- Trial name
- NCT02978118
- Testing
- Immune cell and CTC detection procedures
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Duke University
Cirrhosis, Hepatorenal Syndrome
Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin
Hepatorenal syndrome is a common complication of cirrhotic patients. The prognosis of patients with HRS is very poor. It have been demonstrated that vasoconstrictors agents (Terlipressin) plus albumin are effective in the…
- Trial name
- NCT00287664
- Testing
- terlipressin
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clinic of Barcelona
Pancreatic Cancer, Breast Cancer
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
Study of NGM831 as Monotherapy and in Combination with Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
- Conditions
- Pancreatic Cancer, Breast Cancer, Gastric Cancer, Non-small Cell Lung Cancer
- Trial name
- NCT05215574
- Testing
- NGM831, NGM831 plus pembrolizumab (KEYTRUDA®), NGM831 and NGM438 plus pembrolizumab (KEYTRUDA®)
- Where
- 9 sites in United States
- Volunteers
- 130 people
- Sponsor
- NGM Biopharmaceuticals, Inc
Urinary Calculi
Computed Tomography Evaluation of Urinary Stones Densities Compared to in Vitro Analysis of Its Chemical Composition
The ability to predict stone composition, which influences patient treatment, depends on the accurate measurement of CT attenuation of stones.
- Trial name
- NCT04110574
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Kidney Disease
The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE
The COMBINE clinical trial is a pilot study evaluating the effects of nicotinamide and lanthanum carbonate on serum phosphate and fibroblast growth factor 23 (FGF23) in patients with Chronic Kidney Disease (CKD) stages 3-4.
- Trial name
- COMBINE (NCT02258074)
- Testing
- Nicotinamide, Lanthanum Carbonate
- Where
- 7 sites in United States
- Volunteers
- 205 people
- Sponsor
- The Cleveland Clinic
Bladder Tumor
Microscopic-spectroscopic Examination for Urothelial Tissue Characterization
To evaluate the possibility to properly discriminate between healthy bladder tissue and BCa with a multimodal fiber optic spectroscopy (MFOS) technique, in order to possibly introduce a more objective way to detect BCa, thus…
- Trial name
- MSUT (NCT04310813)
- Testing
- Multimodal spectroscopic analysis
- Volunteers
- 114 people
- Sponsor
- Careggi Hospital
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