Clinical trials: Urologic Surgery
Hypoparathyroidism, Cardiovascular Complication
Cardiovascular, Renal, and Skeletal Complications in Patients With Post-Surgical Hypoparathyroidism
The aim of this observational study is to learn about long term effects to post surgical hypoparathyroidism. The main questions are: 1.
- Conditions
- Hypoparathyroidism, Cardiovascular Complication, Fractures, Bone, Renal Disease
- Trial name
- CAREHYPO (NCT06419270)
- Testing
- Observation
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
The purpose of this study is to compare unilateral spinal anesthesia using hyperbaric Prilocaine with "classical bilateral spinal anesthesia" using plain Prilocaine according to block characteristics and quality of micturition…
- Trial name
- NCT01877356
- Testing
- bilateral spinal anesthesia, unilateral spinal anesthesia
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Antwerp
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse (POP)
Effectiveness of Perineorrhaphy in Pelvic Organ Prolapse Surgery
This is an observational registry-based study of long-term outcome after vaginal native tissue repair for pelvic organ prolapse designed to emulate a pragmatic open-label two-arm trial for which patients, in whom perineorrhaphy…
- Trial name
- PINPOPS (NCT07006129)
- Testing
- Perineorrhaphy, No perineorrhaphy
- Where
- Sweden
- Volunteers
- 40,646 people
- Sponsor
- Lund University
Lower Urinary Tract Symptoms, Voiding Dysfunction
Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods
Background and study aims: The prostate gland sits around the exit of the bladder in men. As men get older, the prostate grows, and this can narrow the exit from the bladder, so that there is restriction of flow.
- Conditions
- Lower Urinary Tract Symptoms, Voiding Dysfunction, Benign Prostate Obstruction, Detrusor Underactivity
- Trial name
- UPSTREAM (NCT02193451)
- Testing
- Urodynamics, Usual care
- Where
- United Kingdom
- Volunteers
- 820 people
- Sponsor
- North Bristol NHS Trust
Urethral Stricture
Tissue-engineered Construct Based on Buccal Mucosa Cells and Matrix From Collagen and Polylactoglycolide Fibers
This study investigates safety and efficacy of surgical treatment of patients with anterior urethral stricture using a tissue-engineered construct based on autologous buccal mucosa cells and matrix from reconstituted collagen and…
- Trial name
- NCT03205670
- Testing
- Urethroplasty with a tissue-engineered construct
- Where
- Russia
- Volunteers
- 6 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Radiation Exposure
Reference Dose Levels During Fluoroscopically Guided Procedures in Operating Rooms
This study is conducted by a working group of the French Society of Medical Physics (SFPM). Its main aim is to establish reference dose levels for the most common procedures performed in operating rooms using mobile X-ray…
- Trial name
- NCT03649451
- Where
- France
- Volunteers
- 8,840 people
- Sponsor
- Societe Francaise de Physique Medicale
Fear of Cancer Recurrence, Renal Cell Carcinoma (Kidney Cancer)
Patient-partnered Research in Investigating Fear of Cancer Recurrence in Kidney Cancer
The goal of this observational study is to gather real-world information about Fear of Cancer Recurrence (FCR) following surgery in patients with renal cell carcinoma (RCC) and their partners/spouses by 1) establishing a panel…
- Trial name
- PP-RECURK (NCT07234656)
- Testing
- Phase 1: Establishment of a patient-partner panel, Phase 2: Feasibility testing of FCR questions, mode of administration and timing for investigating Fear of Cancer Recurrence
- Where
- 3 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Brigitta Rasmussen Villumsen
Stress Urinary Incontinence
Urodynamic Study and Stress Incontinence
A trial to answer the debatabal question about the role of urodynamic study in surgical treatment for stress urinary incontinence.
- Trial name
- NCT03300973
- Testing
- sling surgery
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- Kasr El Aini Hospital
Kidney Cancer
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00908739
- Testing
- gene expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Sponsor
- Case Comprehensive Cancer Center
Kidney Calculi, Quality of Life
Quality of Life in Kidney Stone Patients Undergoing Surgery
This is a prospective randomized study, comparing quality of life in renal stone patients undergoing surgical treatment with ureteroscopy (URS) versus percutaneous nephrolithotomy (PNL).
- Trial name
- NCT02625051
- Testing
- Ureteroscopy, Percutaneous nephrolithotomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Erythropoietin, Acute Kidney Injury
Evaluating Erythropoietin as an Indicator for Possible Kidney Injury After Cardiac Surgery
The purpose of the study is to evaluate kidney biomarkers and determine if there is a correlation between Erythropoietin (EPO) levels and acute kidney injury after cardiac surgery.
- Conditions
- Erythropoietin, Acute Kidney Injury, Renal Biomarker
- Trial name
- EPO (NCT01393418)
- Testing
- Cardiac Surgery
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Analgesia, Epidural, Urodynamics
Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study
Postoperative urinary retention (POUR) is one of the most common complications after surgery and neuraxial anesthesia of which the treatment of choice is bladder catheterization 1.
- Conditions
- Analgesia, Epidural, Urodynamics, Urinary Retention
- Trial name
- NCT01220362
- Testing
- Bupivacain 0.125%, Bupivacain 0.125%/Fentanyl 2mcg/ml
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Bladder Cancer
Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder Cancer
Patients diagnosed with low risk non-muscle invasive bladder cancer (NMIBC) are at risk of frequent low grade recurrence, which usually necessitates surgical intervention under general anaesthetic.
- Trial name
- CALIBER (NCT02070120)
- Testing
- Mitomycin C, Surgical Management
- Where
- 38 sites in United Kingdom
- Volunteers
- 82 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Urinary Incontinence
Polyacrylamide Injection in Patients Ineligible for Surgery
Transurethral injection using polyacrylamide hydrogel (Bulkamid®, Contura A/S, Denmark) is an established treatment for stress urinary incontinence.
- Trial name
- NCT02776423
- Testing
- Bulkamid
- Volunteers
- 81 people
- Sponsor
- Karolinska Institutet
Acute Kidney Injury, Cardiac Surgery
Acute Kidney Injury After Cardiac Surgery
Acute kidney injury (AKI) is common after cardiac surgery. The diagnosis is based on the criteria defined by the Kidney Disease Improving Global Outcomes (KDIGO) classification: oliguria and elevation of serum creatinine.
- Trial name
- NEPHROCAR (NCT03396770)
- Testing
- Standard clinical routine, Nephrocheck test
- Where
- France
- Volunteers
- 848 people
- Sponsor
- Rennes University Hospital
AKI - Acute Kidney Injury
Efficacy and Safety of SP16 in Preventing Acute Kidney Injury in At-risk Subjects With Chronic Kidney Disease Undergoing Elective Cardiac Surgery Using the Heart-lung-machine
This clinical study investigates the safety and potential effectiveness of the investigational drug SP16 in preventing acute kidney injury in patients with pre-existing chronic kidney disease who are undergoing cardiac surgery…
- Trial name
- EASE-AKI (NCT07661940)
- Testing
- SP16-3M
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Kidney Calculi, Nephrolithotomy, Percutaneous
Bilateral Synchronous Simultaneous Stone Surgery
Advancements in technology and endourological armamentarium provides multiple surgical options for complicated stone patients. To avoid multiple operations and shorten the total operation durations, bilateral synchronous…
- Conditions
- Kidney Calculi, Nephrolithotomy, Percutaneous, Ureteroscopy
- Trial name
- NCT03599297
- Testing
- Bilateral synchronous simultaneous stone surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Urologic Diseases
Chart Review of Those Who Have Had Open, Laparoscopic, Ureteroscopic, or Percutaneous Surgery
The investigator intends to review retrospective de-identified data of patients who have had Open, Laparoscopic, Ureteroscopic or Percutaneous Urologic Surgery.
- Trial name
- NCT00395564
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Irvine