Clinical trials: Urologic Surgical Procedure
COVID-19, Urologic Diseases
The Utility of Enhanced Pre and Post-surgical Work-out to Prevent the Spread of COVID-19 in a Large Urology Department
Since the outbreak of COVID-19 hit Spain in March 2020, most of the elective surgeries have been canceled everywhere. As soon as the epidemiology phase of the pandemic changed and the restrictions have been eased, different…
- Conditions
- COVID-19, Urologic Diseases, Surgery--Complications, Epidemic Disease
- Trial name
- UroCovid (NCT04409899)
- Testing
- Blood tests
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio Puigvert
Bladder Cancer
Measuring Surgical Recovery After Radical Cystectomy
The intent of this study is to establish a registry of post-surgical outcomes in patients undergoing radical cystectomy at MD Anderson Cancer Center and the collaborating institutions.
- Trial name
- NCT03193970
- Testing
- Post-Operative Recovery Registry
- Where
- 10 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- M.D. Anderson Cancer Center
Muscle Weakness, Renal Failure
Predictors of Respiratory Failure Following Extubation in the SICU
Respiratory failure following extubation causes significant morbidity and increases mortality in teh surgical intensive care unit (SICU). However the causes of respiratory failure following extubation remain poorly understood.
- Conditions
- Muscle Weakness, Renal Failure, Respiratory Comorbidities
- Trial name
- NCT01967056
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Massachusetts General Hospital
Kidney Stone, Parapelvic Cyst
Percutaneous Nephroscopic Treatment of Parapelvic Cysts
Background of the project: The surgical treatment of parapelvic cysts is currently less researched and there is no gold standard for surgery.
- Conditions
- Kidney Stone, Parapelvic Cyst, Kidney Diseases, Recurrence
- Trial name
- NCT05504512
- Testing
- No intervention
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiangya Hospital of Central South University
Renal Cell Carcinoma, Adrenal Tumor
The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological Telesurgery
A single-arm clinical trial was designed in this study. The surgeon will perform urological telesurgery for patients using Chinese domestically produced "MicroHand S" surgical robot system.
- Conditions
- Renal Cell Carcinoma, Adrenal Tumor, Nonfunctioning Kidney, Renal Pelvis Carcinoma
- Trial name
- NCT05739812
- Testing
- telesurgery by domestic surgical robot
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Urinary Incontinence, Stress, Uterine Prolapse
Colpopexy and Urinary Reduction Efforts (CARE) Protocol
Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery.
- Conditions
- Urinary Incontinence, Stress, Uterine Prolapse, Vaginal Prolapse
- Trial name
- CARE (NCT00065845)
- Testing
- Burch urethropexy at time of sacrocolpopexy
- Where
- 7 sites in United States
- Volunteers
- 322 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hypospadias, Distal Penile Hypospadias (Disorder)
Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomized Trial
This randomized controlled trial evaluates the effect of adding Byar's flap in combination with double dartos flap coverage during tubularized incised plate (TIP) urethroplasty in children with distal hypospadias.
- Trial name
- DD-TIP-BF (NCT07525570)
- Testing
- Double Dartos Flap Coverage, Byar's Flap + Double Dartos Flap
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Javaid Afridi
Kidney Stone, Benign Prostatic Hyperplasia
Utilization of a Web-Based Application to Improve Patient Health Literacy and Reduce Clinic Visit Times in Holmium Laser Enucleation of the Prostate (HoLEP) Procedures and Kidney Stone Surgery
The investigator and research team plan to investigate whether patients who receive access to WellPrept website will report greater confidence and understanding of their medical condition, have shorter clinic visit times, and…
- Trial name
- NCT07580391
- Testing
- WellPrept, Standard Care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prostate Cancer
Nerve-sparing, Robot-assisted Radical Prostatectomy Using a Personalized, 3D-printed Prostate Model for Selective Resection of Positive Surgical Margins
To optimize precision for secondary resection (SR) in frozen section (FS) controlled nerve-sparing robot-assisted radical prostatectomy (NS-RARP) by using a personalized 3D-printed prostate model.
- Trial name
- AURORA (NCT05960669)
- Testing
- 3D model guided secondary resection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Overactive Bladder
Over Active Bladder Patients Having Sling Surgery
The purpose of this study is to determine whether treatment with anti-muscarinic medications following sub-urethral sling procedures improves overall subjective and objective outcomes in women with mixed incontinence with primary…
- Trial name
- NCT00852696
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Florida
Abdominal Surgery, Respiratory Failure
Metabolites of Tramadol in the Postoperative Surgical Patients
Tramadol is opioid analgesic widely used to treat moderate to severe pain. It is metabolized by cytochrome CYP2D6 into two major metabolites: pharmacologically active metabolite O-desmethyltramadol (M1) and inactive…
- Conditions
- Abdominal Surgery, Respiratory Failure, Renal Failure, Liver Dysfunction
- Trial name
- METRAS (NCT04004481)
- Testing
- Postoperative analgesia using tramadol
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Kidney Cancer
A Prospective Post-Market Study to Evaluate the Clinical Utility of IRIS, a Three-dimensional (3-D) Anatomical Modeling Software for Pre-operative Surgical Planning and Intra-operative Navigation for Nephrectomy
This is a prospective, multi-center, post-market study to evaluate the clinical utility of IRIS, a 3D anatomical modeling software, with standard CT scans during pre-operative planning and intra-operative navigation for…
- Trial name
- NCT04329767
- Testing
- IRIS 1.0
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Intuitive Surgical
Kidney Cancer, Renal Cell Carcinoma
Clinical Trial Studying a Personalized Cancer Vaccine in Patients With Non-metastatic Kidney Cancer
This is an international, open label, randomized phase 3 trial in which patients with surgically removable kidney cancer will be randomly selected post-operatively to receive adjuvant treatment with autologous HSPPC-96 or no…
- Trial name
- NCT00126178
- Testing
- HSPPC-96
- Where
- 7 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Agenus Inc.
Kidney Stones
Surgical Outcomes and Costs in Using the Shenzhen HugeMed 6.3 French Flexible Ureteroscope
Comprehensive comparative investigations between HugeMed HU30M 6.3 Fr f-URS and traditional approach f-URS devices in RIRS are lacking in an American population.
- Trial name
- NCT07296835
- Testing
- Ureteroscopy using the 6.3 Fr f-URS hugemed, Hugemed 6.3 Fr f-URS
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Kansas Medical Center
Nephrolithiasis, Kidney Stone
Observational Approach Versus Surgical Intervention for Stones
The aims of the Observational Approach versus Surgical Intervention for Asymptomatic Stone (OASIS) trial are: 1) to determine whether observation compared to upfront surgery results in less healthcare-related life disruption due…
- Trial name
- OASIS (NCT07718802)
- Testing
- Surgery, Observation
- Where
- 4 sites in United States
- Volunteers
- 1,658 people
- Sponsor
- Children's Hospital of Philadelphia
Urinary Incontinence
A 3 Year Follow-up Prospective Open Randomized Trial of TVT Versus Colposuspension for Primary Stress Incontinence
Objective: To compare TVT with COLPOSUSPENSION (CS) as primary treatment for stress incontinence (SUI). Design: Randomised, open, comparative trial 3-years follow-up.
- Trial name
- NCT00782990
- Testing
- Surgical treatment: TVT, Surgical treatment: colposuspension
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Severo Ochoa
Stone, Urinary, Stone, Kidney
Effect of Preop Stent Duration on SFR and Secondary Intervention in RIRS
This study aims to evaluate how placing a stent before surgery (preoperative stenting or passive dilation) affects the success rate of retrograde intrarenal surgery (RIRS), which is performed for kidney stones.
- Trial name
- NCT07052188
- Testing
- without any preoperative stenting, (DJ) stent placed with sedation and undergo RIRS within 2-4 weeks, Patients will have a DJ stent placed with sedation and undergo RIRS within 4-6 weeks.
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Bedreddin Kalyenci
Clear Cell Renal Cell Carcinoma
Cadonilimab Combination With Lenvatinib as Neoadjuvant Therapy for ccRCC
Through the neoadjuvant treatment with a combination of Cadonilimab and Lenvatinib, it enabled the successful and safe implementation of partial nephrectomy in patients with localized renal cancer, who had indications for…
- Trial name
- NCT06138496
- Testing
- Cadonilimab Combined With Lenvatinib
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sun Yat-sen University
Urolithiasis, Stone, Kidney
Registry of MIUS for Urolithiasis (ReMIUS-U)
The purpose of this registry is to collect data on patients who have undergone minimally invasive treatments for urinary system stone disease, including percutaneous nephrolithotomy (PCNL), shock wave lithotripsy (SWL)…
- Conditions
- Urolithiasis, Stone, Kidney, Stone Ureter, Complication of Surgical Procedure
- Trial name
- ReMIUS-U (NCT06394908)
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Marmara University
Postoperative Complication, Respiratory Complications
Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.
This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring.
- Conditions
- Postoperative Complication, Respiratory Complications, Cardiac Complications
- Trial name
- RECOVER (NCT07729891)
- Testing
- Continuous vital sign monitoring with Portrait Mobile in surgical ward
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma