Clinical trials: Usual Care
Patient Decision Aid, Treatment As Usual
Shared Decision Making on Immunotherapy in Oncology
Patients with advanced melanoma are confronted with a serious treatment decision. The current guideline recommends considering the option of immunotherapy with checkpoint inhibitors.
- Trial name
- PEF-Immun (NCT04240717)
- Testing
- Patient Decision Aid
- Where
- 2 sites in Germany
- Volunteers
- 126 people
- Sponsor
- University Hospital Heidelberg
Chronic Nonspecific Neck Pain
Individual Responder Analysis of the Effectiveness of Manual Therapy and Exercise Versus Usual Care in Patients With Chronic Nonspecific Neck Pain
The aim of this study is to compare the effectiveness of a combined intervention of manual therapy and exercise versus usual care, on pain intensity, disability, and global perceived recovery, in patients with chronic nonspecific…
- Trial name
- NCT03560947
- Testing
- Manual Therapy and Exercise (Physiotherapy Intervention), Usual Care (Physiotherapy Intervention)
- Volunteers
- 46 people
- Sponsor
- Universidade Nova de Lisboa
Plantar Fascitis
Photobiomodulation for Plantar Fasciitis
BACKGROUND: Plantar fasciitis, a degenerative injury of the connective tissue in the foot, results in pain-related disability in Service Members and beneficiaries and contributes to decreased physical activity and excessive…
- Trial name
- NCT03015116
- Testing
- Stretching, Cryotherapy, Photobiomodulation Low Power
- Where
- Germany
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Landstuhl Regional Medical Center
Asthma
Asthma Control Test Guided Treatment in Chinese Subjects
This study is aimed to evaluate the effectiveness of Asthma Control Test (ACT) guided treatment compared with usual care in asthma subjects in China.
- Trial name
- NCT02868281
- Testing
- ACT guided Routine Treatment, Routine Treatment
- Where
- 6 sites in China
- Volunteers
- 530 people
- Sponsor
- GlaxoSmithKline
Atrial Fibrillation
Inhibition of Aldosterone to Reduce Myocardial Diffuse Fibrosis in Patients With Paroxysmal and Persistent Atrial Fibrillation in Preventing Recurrent Episodes of Atrial Fibrillation
A randomized, double-blinded, placebo-controlled study to evaluate the effect of spironolactone in addition to conventional treatment compared with placebo in patients with paroxysmal and persistent atrial fibrillation with…
- Trial name
- INSPIRE-AF (NCT02764619)
- Testing
- Spironolactone
- Where
- Denmark
- Volunteers
- 125 people
- Sponsor
- Svendborg Hospital
Chronic Disease, Lung Diseases, Obstructive
Home-based Exercise Training for COPD Patients (HOMEX-2)
The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who did not participate in an inpatient or outpatient rehabilitation program within the last 2 years.
- Conditions
- Chronic Disease, Lung Diseases, Obstructive, Respiratory Disease
- Trial name
- NCT03654092
- Testing
- Exercise
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Esophageal Cancer (EsC)
Patient-Reported Symptom Care Versus Usual Care After Esophageal Cancer Surgery: A Single-Center Phase 3 Randomized Trial
Symptom management is fundamental to clinical care, and symptom monitoring is an effective means to detect potential adverse events early and prevent serious complications.
- Trial name
- NCT07211009
- Testing
- Patient-Reported Outcome (PRO)-Based Symptom Management, Conventional Management
- Volunteers
- 240 people
- Sponsor
- Sichuan University
Heart Valve Disease
CopenHeartVR - Integrated Rehabilitation of Patients After Heart Valve Surgery
The aim of the study is to investigate the effect of an integrated rehabilitation programme, consisting of physical exercise training and psycho-educational consultations, for patients after heart valve surgery.
- Trial name
- CopenHeartVR (NCT01558765)
- Testing
- Integrated rehabilitation
- Where
- Denmark
- Volunteers
- 147 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Fasciitis, Plantar
Comparison of Usual Podiatric Care and Early Physical Therapy for Plantar Heel Pain
Plantar heel pain (PHP) is one of the most common foot conditions in podiatry and physical therapy practice and often is associated with chronic symptoms, and disability.
- Trial name
- NCT01865734
- Testing
- Physical therapy after initial podiatry visit, Usual care provided by podiatry
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Des Moines University
Primary Dysmenorrhea
Manual Acupuncture for Primary Dysmenorrhea
Primary dysmenorrhea (PD) is a common complaint in menstruating women. Although nonsteroidal anti-inflammatory drug is an effective treatment, there are concerns about serious adverse events.
- Trial name
- NCT02783534
- Testing
- Verum acupuncture, Usual care
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huazhong University of Science and Technology
Septic Shock
Pilot Study for the SQUEEZE Trial
The purpose of the SQUEEZE Trial is to determine which fluid resuscitation strategy results in the best outcomes for children treated for suspected or confirmed septic shock.
- Trial name
- SQUEEZE (NCT01973907)
- Testing
- Fluid Sparing Resuscitation Strategy
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- McMaster Children's Hospital
Diabetes Mellitus, Type 2, Diastolic Dysfunction
Effects of Empagliflozin on Left Ventricular Diastolic Function Compared to Usual Care in Type 2 Diabetics
The purpose of the EmDia trial is to compare the effects of empagliflozin with placebo in addition to standard diabetic treatment or dietetic treatment on cardiac diastolic function in patients with type 2 Diabetes mellitus.
- Trial name
- EmDia (NCT02932436)
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 144 people
- Sponsor
- Johannes Gutenberg University Mainz
Cancer
Edinburgh Pain Assessment Tool (EPAT©) Study
To determine if the institutionalisation of a regular systematic approach to the assessment of pain in inpatient cancer units using the Edinburgh Pain Assessment Tool (EPAT©) leads to better control of pain than that achieved by…
- Trial name
- EPAT© (NCT00595777)
- Testing
- EPAT© Educational Package
- Where
- 19 sites in United Kingdom
- Volunteers
- 1,928 people
- Sponsor
- University of Edinburgh
Infantile Colic
Cranial Osteopathy in Infantile Colic
Background Excessive Crying (Infantile Colic) is one of the most common complaints for which parents seek treatment. These otherwise healthy and well fed infants show no signs of failure to thrive, cry without identifiable cause…
- Trial name
- NCT01942928
- Testing
- Usual NHS Care, Osteopathic Manipulative Therapy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- European School of Osteopathy
Hemophilia A
Study of Safety And Efficacy Of ReFacto AF In Previously Untreated Hemophilia A Patients In The Usual Care Setting
Study to evaluate the safety and effectiveness of ReFacto AF for the treatment of severe hemophilia A in patients who have not yet received treatment for their hemophilia.
- Trial name
- NCT00950170
- Testing
- Laboratory Tests
- Where
- 11 sites in France, Germany and 5 more
- Volunteers
- 23 people
- Sponsor
- Pfizer
Withdrawal Syndrome
Protocolized Sedative Weaning VS. Usual Care in Pediatric Critically Ill, RCT
Sedative and analgesic agents are widely used in the ICU. These agents can provide hypnotic effect, pain alleviation, cooperation, and synchronizing ventilatory support.
- Trial name
- NCT03018977
- Testing
- The sedative weaning protocol group, The usual group
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Ramathibodi Hospital
Hypertension
Technology-enabled Management Versus Usual Care for Blood Pressure
Two arm parallel randomized clinical trial
- Trial name
- HrtEx (NCT05479461)
- Testing
- Digital Hypertension Management System, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Opioid Use Disorder
Sublingual Buprenorphine Through Telemedicine vs In-Person Care as Usual
This study will compare in-person induction and maintenance dosing of sublingual buprenorphine to induction and maintenance dosing of sublingual buprenorphine through comprehensive telehealth sessions and telehealth medication…
- Trial name
- NCT05339256
- Testing
- Buprenorphine SL, Telehealth, In-person treatment as usual
- Sponsor
- New York State Psychiatric Institute
Pressure Ulcer
Interdisciplinary Pressure Management & Mobility Program as an Alternative to Usual Care: A Pilot Study
People with spinal cord injuries posses many factors that increase their risk of developing pressure ulcers. Not surprisingly, approximately 82% of persons with spinal cord injury (SCI) will experience a pressure ulcer at…
- Trial name
- WOUND (NCT00796042)
- Testing
- Usual care, Pressure management and Mobility program
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- University of Western Ontario, Canada
Diabetes
Randomized Controlled Clinical Trial of Cinnamon to Lower Hemoglobin A1c
This study will randomize diabetics with hemoglobin A1c greater than 7.0 to receive either cinnamon plus usual care or usual care alone. Hemoglobin A1c will be measured at intake and after 90 days.
- Trial name
- NCT00445354
- Testing
- cinnamon
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Eglin AFB Regional Hospital