Clinical trials: Uterine Cervical Cancer
Cervical Cancer, Immunochemotherapy
Chemo-immunotherapy for Cervical Cancer Stage IIICp Trial
Efficacy evaluation of camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery.
- Trial name
- NCT07167160
- Testing
- Camrelizumab combined with chemotherapy
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Melanoma, Cervical Carcinoma
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors
This is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy and in combination with pembrolizumab; to assess…
- Conditions
- Melanoma, Cervical Carcinoma, Pancreatic Carcinoma, Triple Negative Breast Cancer
- Trial name
- DUET-4 (NCT03849469)
- Testing
- XmAb®22841, Pembrolizumab (Keytruda®)
- Where
- 28 sites in United States
- Volunteers
- 78 people
- Sponsor
- Xencor, Inc.
EGFR Overexpression, Locally Advanced Solid Tumor
Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors
This is a study for people with locally advanced or metastatic cancer for whom previous treatment was not successful. Adults aged 18 and over with advanced cancer with Epidermal Growth Factor Receptor (EGFR) overexpressing can…
- Conditions
- EGFR Overexpression, Locally Advanced Solid Tumor, Metastatic Solid Tumor
- Trial name
- NCT06975410
- Testing
- YH32364
- Where
- 4 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Yuhan Corporation
Cervical Dysplasia
Smoking Cessation in Women With Gynecological Conditions
This feasibility study will compare two smoking cessation methods, traditional nicotine replacement therapy and Electronic Nicotine Delivery Systems (electronic cigarettes) in patients with gynecological conditions.
- Trial name
- NCT01989923
- Testing
- Nicotine Replacement Therapy, Electronic Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cervical Intraepithelial Neoplasia, Trichloroacetic Acid
Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial
To determine the efficacy and HPV clearance of an application of 85% TCA compared to placebo in the treatment of LSIL. This is a randomized, single-blind, placebo-controlled study in 44 women aged 18-65 years with…
- Trial name
- Trichlosil (NCT06525870)
- Testing
- 85%TCA topical application, 3% acetic acid
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Cervical Carcinoma, Dyspareunia
Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors
This randomized pilot trial studies how well fractional carbon dioxide (CO2) laser therapy works in minimizing genitourinary syndrome of menopause (GSM) in gynecological cancer survivors.
- Conditions
- Cervical Carcinoma, Dyspareunia, Endometrial Carcinoma, Ovarian Carcinoma
- Trial name
- NCT03372720
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cervical Cancer
Evaluate Efficacy of the Association Nimotuzumab(HR3) /Cisplatin-Vinorelbine on Patients With Cervical Carcinom
The objective of the present study is to estimate the overall survival of patients with cervical cancer after the administration of monoclonal antibody (mAb) Nimotuzumab (hR3) in combination with chemotherapy of first intention.
- Trial name
- CIMAHOPE (NCT03413579)
- Testing
- Nimotuzumab ( h-R3)
- Where
- 5 sites in Algeria
- Volunteers
- 37 people
- Sponsor
- El Kendi Pharmaceuticals Manufacturing Company
Cervical Cancer
Immunogenicity and Safety Study of NBP615 in Healthy Female
This was a randomized, double-blind, active-controlled, phase I/II clinical trial to enroll 200 healthy female including 80 healthy adult aged 19 to 26 years and 120 adolescents aged 9 to 13 years.
- Trial name
- NCT04453241
- Testing
- NBP615, Gardasil
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- SK Bioscience Co., Ltd.
HPV, HPV Associated Cancers
Emergency Department-based Cervical Cancer Screening Through Self-sampling
This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.
- Conditions
- HPV, HPV Associated Cancers, HPV Cancers, Cervical Cancer Screening
- Trial name
- NCT07345897
- Testing
- Cervical Cancer Screening
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Cancer of Ovary, Endometrium Cancer
The Effect of Logotherapy on Mental Health in Gynecological Cancer Patients
Gynecological cancers negatively affect women's sexuality, fertility, body image, and self-perception, resulting in deterioration in their psychological health.
- Conditions
- Cancer of Ovary, Endometrium Cancer, Cervix Cancer
- Trial name
- NCT05246462
- Testing
- Logotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cervical Cancer
A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening
Objective: The main objective of this study is to verify the level of comfort for patients and the degree of cervical visibility for health providers using a novel smart speculum compared to the standard speculum.
- Trial name
- NCT06359431
- Testing
- Novel Smart Speculum, Standard speculum
- Where
- Cameroon
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GICMED
Locally Advanced Cervical Cancer, Cachexia
A Clinical Study of Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Cervical cancer, ranking as the fourth most prevalent malignancy in women globally, presents significant challenges in nutritional management.
- Trial name
- NCT07338487
- Testing
- Nanocrystalline Megestrol Acetate Oral Suspension
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Second Xiangya Hospital of Central South University
Breast Cancer, Cervical Cancer
Unidas Por Vida y Salud: Increasing Breast and Cervical Cancer Screening in El Paso
The purpose of this study is to develop, implement and evaluate a comprehensive breast and cervical cancer screening program designed to increase uptake of breast and cervical cancer screening among rarely and never-screened…
- Trial name
- NCT04397744
- Testing
- Unidas por Vida y Salud prevention program
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer, Ovarian Cancer
Study of Immune Response Modifier in the Treatment of Breast, Ovarian, Endometrial and Cervical Cancers
The purpose of this study is to evaluate the anti-tumor activity of 852A when used to treat metastatic breast, ovarian, endometrial or cervical cancer not responding to standard treatment.
- Conditions
- Breast Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT00319748
- Testing
- 852A
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Uterine Cervical Cancer, Diffusion-weighted MRI
Diffusion MRI; Predictive Value for Cervical Uterine Cancer Recurrence
Uterine cervical cancer is the second most common female malignancy. Therapy monitoring is essential to detect early recurrence.
- Conditions
- Uterine Cervical Cancer, Diffusion-weighted MRI, Recurrence
- Trial name
- s52647 (NCT01226264)
- Testing
- Diffusion weighted MRI (DW- MRI)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cervical Cancer
A Randomized Study to Compare a Hydrogel Packing System to Standard Packing During HDR Brachytherapy for Cervical Cancer
In this study, a new, low cost packing system ("BrachyGel VHPS") is being tested as a packing option during brachytherapy along with standard options to make sure that it keeps the unrelated organs away from radiation at least as…
- Trial name
- NCT04499521
- Testing
- BrachyGel VHPS
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Virginia
Gynecological Tumor, Adaptive Radiotherapy
Adaptive Radiotherapy in Patients With Gynecological Tumors
Prospective randomized evaluation of adaptive radiotherapy in the definitive radiotherapy of locally advanced gynecologic carcinoma (e.g.
- Conditions
- Gynecological Tumor, Adaptive Radiotherapy, Radiation, Curative Treatment
- Trial name
- ProART (NCT06230549)
- Testing
- Adaptive Radiotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Cervical Dysplasia
Can Alternative Treatment Have an Impact on Cervical Dysplasia?
In this study two questions will be answered: can mindfulness meditation help cell-changed on the cervix to disappear? can mindfulness meditation lower the psychological distress when women have abnormal cervical cancer screening…
- Trial name
- NCT00842738
- Testing
- Mindfulness meditation, No meditation, Controls
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Head and Neck Cancer, Cervical Cancer
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies
This is a multicenter, open-label, phase Ib/IIa study. The first part of the study will evaluate the safety, tolerability and preliminary efficacy of ILB2109 and Toripalimab in patients with locally advanced or metastatic solid…
- Conditions
- Head and Neck Cancer, Cervical Cancer, Endometrial Cancer, Triple Negative Breast Cancer
- Trial name
- NCT05955105
- Testing
- ILB-2109, Toripalimab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Innolake Biopharm
Healthy, Adolescents
Integration to Improve Adolescent Health and HPV Vaccination in Laos
The goal of this study is to find out if adding HPV vaccination to adolescent health services works to increase HPV vaccine uptake in 10-13-year-old girls in Laos.
- Conditions
- Healthy, Adolescents, Integrated, Community-Health Systems, HPV Vaccines
- Trial name
- NCT06650956
- Testing
- Integrated HPV and SRH Service Package, Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant
- Where
- Laos
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Health Poverty Action