Clinical trials: Uterine Cervical Neoplasms
Cancer of Endometrium, Cancer of Cervix
Efficacy of PENS of the Auricle as an Opioid Sparing Postoperative Analgesic Technique in Cancer Endometrium and Cancer Cervix Patients
Pain relief following laparotomy surgery requires a variety of techniques including invasive ones like epidural or nerve blocks along with different classes of drugs, out of which opioids are most predominant.
- Trial name
- NCT05742711
- Testing
- Primary Relief
- Where
- India
- Volunteers
- 48 people
- Sponsor
- DyAnsys, Inc.
HPV Infection, Cervix Cancer
Prevention and Screening Towards Elimination of Cervical Cancer
The research project applies the protocol of the World Health Organisation for screening of cervical cancer, with testing of hrHPV as first screening, followed by Visual Inspection of the cervix with Acetic Acid for…
- Conditions
- HPV Infection, Cervix Cancer, Cervical Dysplasia
- Trial name
- PRESCRIP-TEC (NCT05234112)
- Testing
- Community mobilisation for hrHPV self-testing, hrHPV self-testing, Follow-up after testing
- Where
- Uganda
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Colposcopy
Investigation of the Uterine Cervix Using CervicalMD
The purpose of this study is to demonstrate the CervicalMD device's ability to collect digital imagery suitable for a colposcopy examination.
- Trial name
- NCT00839475
- Volunteers
- 26 people
- Sponsor
- STI-Medical Systems
Cervical Cancer
S0227 Cisplatin With Either Paclitaxel or Gemcitabine in Recurrent, Persistent, or Metastatic Cervical Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00057928
- Testing
- cisplatin, gemcitabine hydrochloride, paclitaxel
- Where
- 106 sites in United States, Canada
- Sponsor
- SWOG Cancer Research Network
Cervical Cancer, Endometrial Cancer
Liposomal Doxorubicin and Carboplatin in Treating Patients With Gynecologic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00032162
- Testing
- carboplatin, pegylated liposomal doxorubicin hydrochloride
- Where
- 19 sites in Germany
- Volunteers
- 63 people
- Sponsor
- AGO Study Group
Neoadjuvant Immunotherapy, Cervical Cancer
Phase II Study on Neoadjuvant Therapy of AK104 Combined With Nab-paclitaxel/Carboplatin in Fertility Preserving Surgery
This is a Phase II study of neoadjuvant therapy of AK104 combined with nab-paclitaxel/carboplatin in fertility saving surgery for stage IB2-IB3 cervical cancer (FIGO 2018).
- Conditions
- Neoadjuvant Immunotherapy, Cervical Cancer, Fertility-sparing Surgery
- Trial name
- NCT06209294
- Testing
- AK104, Carboplatin, Nab paclitaxel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xiaohua Wu
Solid Tumor, Colorectal Cancer
Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors
This is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in combination with pembrolizumab to determine its maximum…
- Conditions
- Solid Tumor, Colorectal Cancer, Non Small Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck
- Trial name
- NCT04344795
- Testing
- TPST-1495 twice daily, TPST-1495 once daily or on intermittent schedule, Pembrolizumab
- Where
- 11 sites in United States
- Volunteers
- 89 people
- Sponsor
- Tempest Therapeutics
Cervical Cancer
Extraperitoneal Lymph Node Dissection in Patients With Cervical Cancer
Primary Objectives: To determine the feasibility of performing an extraperitoneal laparoscopic lymphadenectomy in patients with stage IB2-IVA cervical carcinoma who are dispositioned to undergo radiotherapy and concurrent…
- Trial name
- NCT00500435
- Testing
- Extraperitoneal Laparoscopic Lymphadenectomy
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Cervical Cancer
Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy With or Without Bevacizumab in Women With Recurrent, or Metastatic Cervical Cancer
This is a Phase 2, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of QL1706 Plus Chemotherapy in Women With Recurrent, or Metastatic…
- Trial name
- NCT05179317
- Testing
- QL1706
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Cervical Cancer
Cervical Carcinoma in Shatby University Hospital and Its Relation to Human Papilloma Virus
incidence of detection of carcinogenic types of human papilloma virus in 60 cases of cervical cancer
- Trial name
- NCT05539274
- Testing
- human papilloma virus testing and genotyping in cervical cancer cases
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Hossam Hassan Aly Hassan El Sokkary
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may…
- Conditions
- Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma
- Trial name
- NCT02834013
- Testing
- Biospecimen Collection, Computed Tomography, Echocardiography Test
- Where
- 1,007 sites in United States, Guam
- Volunteers
- 798 people
- Sponsor
- National Cancer Institute (NCI)
Uterine Cervical Neoplasms
Feasibility of ReSpace™ Hydrogel to Establish a Stable Cervical-rectal Space
In this study, 5 subjects will be enrolled and the cumulative D2cc dose for rectum during brachytherapy will be recorded as the primary outcome measures.
- Trial name
- NCT05369221
- Testing
- ReSpace™
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Peking Union Medical College Hospital
Human Papillomavirus DNA Tests, Cervical Cancer
IT-system Development for Reaching Cervix Cancer Screening Non-attenders
The main purpose is to develop and test an IT-infrastructure to provide more individualized ways of inviting and reaching women who have not participated, despite having been invited with annual reminders, in cervix cancer…
- Trial name
- NCT02750124
- Testing
- Cobas PCR Female swab sample Packet, Routine practice
- Volunteers
- 8,000 people
- Sponsor
- Karolinska Institutet
Recurrent Cervical Cancer, Stage IIIA Cervical Cancer
Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer
This phase II trial studies how well eribulin mesylate works in treating patients with advanced or recurrent cervical cancer. Drugs used in chemotherapy, such as eribulin mesylate, work in different ways to stop the growth of…
- Conditions
- Recurrent Cervical Cancer, Stage IIIA Cervical Cancer, Stage IIIB Cervical Cancer, Stage IVA Cervical Cancer
- Trial name
- NCT01676818
- Testing
- eribulin mesylate
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Southern California
Cervical Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
- Trial name
- ROCC (NCT04831580)
- Testing
- da Vinci, open surgery
- Where
- 156 sites in United States, Brazil and 2 more
- Volunteers
- 840 people
- Sponsor
- GOG Foundation
Ovarian Cancer, Triple-Negative Breast Cancer
Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)
SCANDARE is a prospective biobanking study on tumor (+/- nodes), plasma and blood samples at different time points in ovarian, triple negative breast, Head and Neck Cancer, advanced stage treatment-naïve cervical or vulva cancer…
- Conditions
- Ovarian Cancer, Triple-Negative Breast Cancer, Head and Neck Cancer, Cervical Cancer
- Trial name
- SCANDARE (NCT03017573)
- Testing
- Tumor biopsies / Tumor surgery, Blood withdrawal
- Where
- 6 sites in France
- Volunteers
- 1,050 people
- Sponsor
- Institut Curie
Cervical Cancer, LSIL
oncoFISH Cervical Test for Detection of 3q26 Region Gain
The purpose of this study is to evaluate the use of the oncoFISH cervical test system in the management of women who have received an LSIL Pap report to determine whether the test can predict which women will progress to more…
- Trial name
- NCT01416922
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Ikonisys, Inc.
Locally Advanced Cancer, Cervical Cancer
Carboplatin-Paclitaxel Adjuvant Chemotherapy in the Treatment of Locally Advanced Cervical Cancer
This is a mutlicentric, open-label non-randomized, national, 2-stage phase II trial to assess efficacy and safety of a weekly Carboplatin-Paclitaxel adjuvant chemotherapy after intensity modulated extended-field chemoradiation in…
- Trial name
- ACCRAPAN (NCT04016142)
- Testing
- Carboplatin-Paclitaxel adjuvant chemotherapy
- Where
- 6 sites in France
- Volunteers
- 21 people
- Sponsor
- Centre Oscar Lambret
Uterine Cervical Cancer
Evaluation of Long-term HPV Vaccine Efficacy
Summary For ethical and practical reasons pre-licensure clinical efficacy phase III trials for GSK Biologicals' HPV-16/18 LI VLP AS04 vaccine used cervical intraepithelial grade 2 and above (CIN2+) lesions as surrogate efficacy…
- Trial name
- NCT01393470
- Testing
- Screening for cervical cancer
- Where
- 15 sites in Finland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Tampere University
Cervical Intraepithelial Neoplasia III
Treatment of Cervical Intraepithelial Neoplasia (CIN) Grade III With Non-invasive Physical Plasma
The aim of the prospective, unicenter proof-of-principle study is to investigate the anti-neoplastic effectiveness of NIPP against CIN III lesions.
- Trial name
- ZGynO_CINIII (NCT04753073)
- Testing
- Non-invasive physical plasma
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- University Hospital Tuebingen