Clinical trials: Uterine Disease
Postpartum Hemorrhage
Controlled Cord Traction During Third Stage of Labor
Of the estimated number of 529,000 maternal deaths for the year 2000, 132,000 (25%) were caused by postpartum hemorrhage (PPH); 99% of these deaths occurred in low-income countries.
- Trial name
- CCT (NCT00781066)
- Testing
- Controlled cord traction, No controlled cord traction
- Where
- 2 sites in Uruguay
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidad de la Republica
Scar; Previous Cesarean Section, Complications; Cesarean Section, Wound, Dehiscence
Optimization of the Healing Process of the Uterine Scar Tissue After Re-cesarean Section
This prospective, controlled, clinical, intervention study measures the number of uterine Cesarean section scars and median myometrial thickness of women who underwent two Cesarean sections six to nine months after their last…
- Trial name
- OPSTAR (NCT02703519)
- Testing
- resection of uterine scar tissue
- Where
- 2 sites in Germany
- Volunteers
- 116 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Endometrial Neoplasms, Neoplasm Recurrence, Local
Cadonilimab With Chemoradiation for Recurrent and Oligometastatic Endometrial Carcinoma
The goal of this clinical trial is to evaluate the efficacy and safety of cadonilimab in combination with paclitaxel, cisplatin, and radiation therapy for the treatment of locally recurrent and oligometastatic endometrial…
- Conditions
- Endometrial Neoplasms, Neoplasm Recurrence, Local, Neoplasm Metastasis
- Trial name
- NCT06532539
- Testing
- Paclitaxel and Cisplatin, Cadonilimab, Radiotherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shandong Cancer Hospital and Institute
Cervical Cancer, Pathological Screening Smear
Comparison of 2 Types of Cervical Specimens in Patients With a Pathological Screening Smear
The recommendations on the method and the realization of the cervico-uterine smears are clear. With regard to performing endocervical curettage, several methods are possible without precise consensus.
- Trial name
- ENDOCOL (NCT04000477)
- Testing
- Cytobrush, Kevorkian curette
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Lille
Diagnosis
Uterine Artery Diastolic Notching & Apelin-13 and 36
This study was conducted to investigate the relationship between diastolic notching on uterine artery Doppler and serum apelin-13 and 36 concentrations between 11 and 14 weeks of gestation.
- Trial name
- NCT06390202
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Fertility
Fertility Post Placenta Accrete
This study is the first to investigate the fertility outcome and the influence on ovarian reserve after using uterine artery embolization during cesarean delivery.
- Trial name
- CSAC (NCT02821702)
- Testing
- Vaginal ultrasound, Blood sample
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cervical Cancer, Condylomata Acuminata
Immunogenicity of a Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58)Vaccine(E.Coli) Versus Gardasil®9 in Healthy Females 18-26 Years of Age
This study is designed to compare the immunogenicity of a novel recombinant human papillomavirus vaccine (types 6,11,16,18,31,33,45,52,58 )(E.Coli) manufactured by Xiamen Innovax Biotech CO., Ltd., with Gardasil®9 in females…
- Trial name
- NCT04782895
- Testing
- Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), Gardasil®9
- Where
- China
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Endometrial Cancer, Cervical Cancer
Tachosil for the Prevention of Symptomatic Lymph Cysts
This is a randomized trial of 140 women with endometrial or cervical cancer undergoing removal of lymph tissue (lymphadenectomy).
- Trial name
- NCT01470677
- Testing
- Tachosil fibrin patch
- Where
- 2 sites in Austria, Germany
- Volunteers
- 220 people
- Sponsor
- Ruhr University of Bochum
Uterine Fibroids, Heavy Menstrual Bleeding
Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women
This study seeks to evaluate the efficacy, safety and tolerability of elagolix alone and in combination with estradiol/norethindrone acetate for the management of heavy menstrual bleeding associated with uterine fibroids in…
- Trial name
- NCT02654054
- Testing
- Elagolix, Estradiol/Norethindrone Acetate
- Where
- 96 sites in United States, Canada and 1 more
- Volunteers
- 413 people
- Sponsor
- AbbVie
Stage IB2 Cervical Cancer, Stage II Cervical Cancer
Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer
GYNECO 02 hypothesis is that hysterectomy reduces the possibility of local or loco-regional relapse, especially in patient with a reduced metastatic risk and who received a local chemoradiation therapy with an increase of…
- Conditions
- Stage IB2 Cervical Cancer, Stage II Cervical Cancer, Adenocarcinoma, Squamous Cell Carcinoma
- Trial name
- NCT01363466
- Testing
- hysterectomy
- Where
- 35 sites in France
- Volunteers
- 61 people
- Sponsor
- UNICANCER
Cardiovascular Diseases, Osteoporosis
Macrobiotic Diet and Flax Seed: Effects on Estrogens, Phytoestrogens, & Fibrinolytic Factors
This study will assess whether alternative, high phytoestrogen dietary interventions result in favorable effects on biological parameters that have been associated with hormone-dependent cancers, cardiovascular disease, and…
- Conditions
- Cardiovascular Diseases, Osteoporosis, Breast Cancer, Endometrial Cancer
- Trial name
- NCT00010829
- Testing
- American Heart Association Step 1 diet, American Heart Association Step 2 diet + 10 g/day flax seed, Macrobiotic dietary intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Anti-Mullerian Hormone Deficiency, Post Partum Hemorrhage
Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. There are many studies about AMH changes in ovarian surgery, but little is known for other surgeries.
- Trial name
- NCT03907605
- Testing
- anti- mullerian hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postpartum Hemorrhage
Misoprostol for Secondary Prevention of Postpartum Hemorrhage at the Community Level in India
This study compares two community-level strategies: selective administration of 800 mcg sublingual misoprostol to women at 350 mL blood loss for secondary prevention of postpartum hemorrhage (PPH) with universal use of 600 mcg…
- Trial name
- NCT01462422
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 3,032 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Myoma, Adenomyosis
To Compare to 2-channel and Multiple-channel Single Port Laparoscopic-assisted Vaginal Hysterectomy
The main objective of this trial is to assess the efficacy and safety of single port-access laparoscopic-assisted vaginal hysterectomy.
- Trial name
- NCT01564602
- Testing
- comparison multiple channel port laparoscopic surgery
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Menorrhagia, Abnormal Uterine Bleeding
Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual Bleeding
The goal of this clinical trial is to determine if calcium dobesilate is an effective alternative to tranexamic acid for treating menorrhagia in women aged 18 to 39 years.
- Trial name
- NCT06763094
- Testing
- Calcium dobesilate (Doxium), Tranexamic Acid
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Uterine Cervical Dysplasia, Uterine Cervix Cancer
The SAFE Study: Satisfaction and Adherence to Follow-Up With Colposcopy Exams
This study is intended to improve the patient experience of communication of colposcopy results and follow-up recommendations to patients.
- Trial name
- NCT03296566
- Testing
- Patient Liaison
- Where
- Canada
- Volunteers
- 297 people
- Sponsor
- University of British Columbia
Cervical Intraepithelial Neoplasia
Evaluation of Human Papilloma Virus (HPV) Self-testing to Increase Screening Uptake
Cervical cancer is a leading cause of mortality among women in developing countries. A key factor has been the failure to achieve good coverage.
- Trial name
- EMA (NCT02095561)
- Testing
- HPV self testing
- Where
- Argentina
- Volunteers
- 6,013 people
- Sponsor
- Instituto Nacional del Cáncer, Argentina
Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole
Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia
Randomized phase III trial to compare the effectiveness of methotrexate with that of dactinomycin in treating patients who have gestational trophoblastic neoplasia.
- Conditions
- Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole, Non-Metastatic Gestational Trophoblastic Tumor, Uterine Corpus Choriocarcinoma
- Trial name
- NCT00003702
- Testing
- Dactinomycin, Methotrexate
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Gynecologic Oncology Group
Cervical Cancer
New Indications for Ultrasound in the Staging of Cervical Cancer
The purpose is to investigate and evaluate two new diagnostic methods using ultrasound in the staging of cervical cancer. 1. 3-D-ultrasound of the tumour to estimate its volume and local spread 2.
- Trial name
- NCT00451945
- Testing
- biopsy, 3d-ultrasound and fusion of UL and PET/CT
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervix; Intraepithelial Neoplasia
Depth of Necrosis in Normal Cervical Epithelium After 85% Trichloroacetic Acid (TCA) Application
Early detection and treatment of precancerous lesions are the pillars of cervical cancer prevention. Cervical Intraepithelial Neoplasia (CIN) is a precancerous lesion that histologically can be found in one of three stages of…
- Trial name
- NCT04911075
- Testing
- 85% TCA Solution
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
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