Clinical trials: Uterine Diseases
Endometrial Cancer, Lynch Syndrome
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer.
- Conditions
- Endometrial Cancer, Lynch Syndrome, Screening, Early Detection of Cancer
- Trial name
- SCREEN-CUP (NCT07220239)
- Testing
- Menstrual cup use
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jessica D. St. Laurent, MD
Prostate Cancer, Hepatocellular Carcinoma
68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors
This study aims to evaluate a novel dual-targeted PET imaging tracer, 68Ga-FAPI-PSMA, for the detection and evaluation of solid tumors.
- Conditions
- Prostate Cancer, Hepatocellular Carcinoma, Ovarian Cancer, Solid Tumors
- Trial name
- NCT07639801
- Testing
- 68Ga-FAPI-PSMA, 68Ga-PSMA-617, 68Ga-FAPI-04
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
Pregnancy, Primiparity
MorbiMortality Amelioration in Preeclamptic Primiparas Study. MoMA Pre Prim Study
The purpose of this study is to determine whether close monitoring of patients with a high sFlt1 plasma level between 25 and 28 weeks of gestation (i.e.
- Conditions
- Pregnancy, Primiparity, Hypertension, Preeclampsia
- Trial name
- MOMA (NCT00763672)
- Testing
- Transmission of sFlt-1 results to the investigator, No transmission of the sFlt-1 results to the investigator
- Where
- France
- Volunteers
- 1,040 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Primary Peritoneal Carcinoma, Tumor
Feasibility Study of Pazopanib in Combination With Chemotherapy in Gynaecological Tumors
This is an open-label, two-arm, multicenter feasibility study to evaluate the safety and tolerability of pazopanib in combination with carboplatin and paclitaxel in female subjects with newly diagnosed advanced gynaecological…
- Conditions
- Primary Peritoneal Carcinoma, Tumor, Epithelial Ovarian Cancer, Uterine Disease
- Trial name
- NCT00561795
- Testing
- pazopanib (GW786034), carboplatin, paclitaxel
- Where
- 5 sites in France, Germany
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Postpartum Hemorrhage
Management of Postpartum Haemorrhage and Effect of Geographic Region
Background: Maternal deaths occur universally and are largely avoidable. Postpartum haemorrhage accounts for a disproportionate amount of maternal deaths.
- Trial name
- NCT03166839
- Testing
- Experiencing PPH
- Volunteers
- 20,060 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic
Evaluating Efficacy and Tolerability of Anticancer Drug Therapies for the Treatment of Gynecologic and Breast Cancers
retrospective/prospective observational study. Objective of the study is to evaluate the effect of drugs in terms of objective responses, disease-free survival (DFS), progression-free survival (PFS), overall survival (OS), and…
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic, Ovarian Cancer, Cervical Carcinoma
- Trial name
- NCT06800612
- Testing
- Oncologic drugs administered for treatment of breast cancer, Oncologic drug administered for treatment of gynecologic cancer
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
HPV-Related Cervical Carcinoma, Inflammatory Bowel Diseases
HPV Infection and Cervical Neoplasm in Women With Inflammatory Bowel Disease: a Cross-sectional Study
The associations between female inflammatory bowel disease (IBD) patients and human papilloma virus (HPV) infection and cervical neoplasia (dysplasia or cancer) were unclear.
- Conditions
- HPV-Related Cervical Carcinoma, Inflammatory Bowel Diseases, Cervical Neoplasm
- Trial name
- NCT03055130
- Testing
- Thinprep Cytology Test (TCT) and HPV infection types were tested by gynecologist
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pancreatic Neoplasms, Stomach Neoplasms
Robotic vs Laparoscopic and Open Surgery for Abdominopelvic Cancers
Robotic surgery has become an increasingly common option for treating cancers in the abdomen and pelvis. However, whether robotic surgery leads to better cancer-related outcomes than laparoscopic (keyhole) surgery or open surgery…
- Conditions
- Pancreatic Neoplasms, Stomach Neoplasms, Rectal Neoplasms, Uterine Cervical Neoplasms
- Trial name
- NCT07821775
- Testing
- No Intervention: Observational Cohort
- Where
- South Korea
- Volunteers
- 32,949 people
- Sponsor
- Asan Medical Center
Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma
Cabozantinib S-Malate in Treating Patients With Recurrent or Metastatic Endometrial Cancer
This phase II trial studies how well cabozantinib s-malate works in treating patients with endometrial cancer that has come back (recurrent) or has spread to other places in the body (metastatic).
- Conditions
- Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma
- Trial name
- NCT01935934
- Testing
- Cabozantinib S-malate, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 19 sites in United States, Canada
- Volunteers
- 102 people
- Sponsor
- National Cancer Institute (NCI)
Cancer of the Uterine Cervix
Magnetic Resonance Imaging (MRI) Staging of Cervix Cancer
The researchers propose that it may be corpus invasion, rather than tumour volume per se, which is one of the important determinants of ultimate outcome in cervix cancer.
- Trial name
- NCT00193934
- Where
- 16 sites in United States, Australia and 3 more
- Volunteers
- 109 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Endometrial Cancer
Frontline Immunotherapy Combined With Radiation and Chemotherapy in High Risk Endometrial Cancer
The purpose of this single arm, open label study is to evaluate the feasibility of pembrolizumab combined with radiation administered to the upper part of the vagina (vaginal cuff brachytherapy) followed by three cycles of…
- Trial name
- FIERCE (NCT03932409)
- Testing
- Pembrolizumab, Vaginal cuff brachytherapy (VCB), Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Oklahoma
Uterine Cervical Dysplasia
Hemostatic Procedure After Biopsy of the Cervix
Cytological abnormalities of the Cervix uteri need to be clarified by colposcopy biopsy. To avoid bleeding after biopsy, monsel´s paste is a common used Agent.
- Trial name
- NCT02486471
- Testing
- Monsel´s Paste, Wait and see
- Where
- 2 sites in Germany
- Volunteers
- 166 people
- Sponsor
- Zydolab - Institute of Cytology and Immune Cytochemistry
Adenomyosis, Uterine Leiomyoma
The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms
The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02495311
- Testing
- myomectomy or adenomyomectomy
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Uterine Prolapse, Stage III
GYNECARE PROSIMA* Procedure Versus Modified Total Pelvic Floor Reconstructive Surgery for Uterine Prolapse Stage III
Pelvic Organ prolapse (a feeling of bulge in the vagina) may cause some distressing symptoms such as loss of control of the bowel or bladder, and may also cause problems with patient's sex life.
- Trial name
- NCT01396109
- Testing
- Procedure: TVH and GYNECARE PROSIMA* Pelvic Floor Repair System, Procedure: TVH and Modified Pelvic Floor Reconstruction Surgery with mesh
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Cervical Cancer
Promoting Comprehensive Cervical Cancer Prevention and Better Women Health in Cameroon
In sub-Saharan Africa, cervical cancer is the leading cause of cancer death among women because of the difficulty in implementing screening programs.
- Trial name
- PCCCP (NCT03757299)
- Testing
- HPV Test
- Where
- Switzerland
- Volunteers
- 4,473 people, healthy volunteers welcome
- Sponsor
- Prof. Patrick Petignat
Pregnancy Related, Pregnancy Complications
MYFEMBREE®: A Retrospective Cohort Study Using an Administrative Healthcare Database to Assess Pregnancy Outcomes in Women Treated With Relugolix Combination Therapy
This is a retrospective cohort study that will be conducted using secondary de-identified electronic healthcare data (EHD) that originally were collected for the purposes of health insurance billing and/or routine patient care…
- Conditions
- Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk
- Trial name
- NCT05739136
- Testing
- Relugolix + Estradiol + Norethindrone Acetate
- Where
- United States
- Volunteers
- 530 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Uterine Cervical Cancer, Diffusion-weighted MRI
Diffusion MRI; Predictive Value for Cervical Uterine Cancer Recurrence
Uterine cervical cancer is the second most common female malignancy. Therapy monitoring is essential to detect early recurrence.
- Conditions
- Uterine Cervical Cancer, Diffusion-weighted MRI, Recurrence
- Trial name
- s52647 (NCT01226264)
- Testing
- Diffusion weighted MRI (DW- MRI)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Uterine Cervical Cancer
Adjuvant Chemotherapy for Locally Advanced Cervical Cancer
Data of survival benefit from adjuvant chemotherapy (ACT) after concurrent chemoradiation (CCRT) for locally advanced cervical cancer (LACC) are still limited and inconsistent.
- Trial name
- ACT-LACC (NCT02036164)
- Testing
- Pelvic radiation, Cisplatin, Paclitaxel
- Where
- 11 sites in Thailand
- Volunteers
- 500 people
- Sponsor
- Siriwan Tangjitgamol, MD
Cervical Cancer, Stage IIB
Curcumin in Advanced Cervical Cancer
Determine the efficacy and safety of turmeric in the treatment of patients with advanced cervical cancer. Efficacy will be determined through radiological and histopathological criteria through the rate of response to treatment…
- Trial name
- NCT04294836
- Testing
- Curcumin
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
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