Clinical trials: Uterine Diseases
Cervical Cancer, Immunochemotherapy
Chemo-immunotherapy for Cervical Cancer Stage IIICp Trial
Efficacy evaluation of camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery.
- Trial name
- NCT07167160
- Testing
- Camrelizumab combined with chemotherapy
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Postpartum Hemorrhage, Pregnancy
RCT of Misoprostol for Postpartum Hemorrhage in India
Death rates for pregnant women in rural India are approximately forty-five times higher than in the United States. Bleeding after the birth of a child and underlying anemia are the primary causes of mothers' deaths and sickness…
- Trial name
- NCT00097123
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Gynecologic Cancer
Evaluation of Robot-Assisted Surgery in Gynecologic Oncology
The goal of this observational study is to collect information about the length of surgery, the procedures performed during surgery, and any possible side effects of robot-assisted gynecologic cancer surgeries.
- Trial name
- NCT00671827
- Testing
- Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 588 people
- Sponsor
- M.D. Anderson Cancer Center
Female Genital Diseases, Ovarian Cancer
Prospective Evaluation of Lymphoedema Among Patients With Gynaecological Cancer
This project will conduct a prospective, longitudinal, observational cohort study to assess the onset and incidence of lymphoedema, as well as investigate factors associated with its development among women newly diagnosed with…
- Conditions
- Female Genital Diseases, Ovarian Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LEGS (NCT00604994)
- Where
- 6 sites in Australia
- Volunteers
- 761 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
Intrauterine Adhesion
The Efficacy and Safety of Disposable Balloon Uterine Stent in Patients With Asherman Syndrome
Asherman's syndrome is characterized by the presence of intrauterine adhesions (IUA) as well as symptoms such as amenorrhea, hypomenorrhea, pelvic pain, and infertility.
- Trial name
- NCT03330873
- Testing
- disposable balloon uterine stent, Foley catheter
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Cervical Cancer, LSIL
oncoFISH Cervical Test for Detection of 3q26 Region Gain
The purpose of this study is to evaluate the use of the oncoFISH cervical test system in the management of women who have received an LSIL Pap report to determine whether the test can predict which women will progress to more…
- Trial name
- NCT01416922
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Ikonisys, Inc.
Cervical Intraepithelial Neoplasia (CIN), Genital Warts
Impact of HPV Vaccination Against Cervical Lesions and Genital Warts in Colombia. an Ecological Assessment
The goal of this observational study is to assess the impact of HPV vaccination on cervical lesions and genital warts in Colombian birth cohorts.
- Conditions
- Cervical Intraepithelial Neoplasia (CIN), Genital Warts, Papillomavirus Infections, Cervical Cancers
- Trial name
- NCT06700941
- Testing
- HPV vaccine
- Where
- Colombia
- Volunteers
- 8,000,000 people
- Sponsor
- Universidad Nacional de Colombia
Cancer of Head and Neck, Lung Cancer, Nonsmall Cell
A Multicenter Cancer Biospecimen Collection Study
This study will collect de-identified tumor samples, with correlated clinical/demographic data and tissue histology, from patients selected or scheduled for pre-treatment tumor biopsy or who have had a recent pre-treatment tumor…
- Conditions
- Cancer of Head and Neck, Lung Cancer, Nonsmall Cell, Small-cell Lung Cancer, Urothelial Carcinoma
- Trial name
- NCT04510129
- Testing
- OncoPrism™ assay
- Where
- United States
- Volunteers
- 1,650 people
- Sponsor
- Cofactor Genomics, Inc.
Menorrhagia, Metrorrhagia
Severity of Bleeding as a Predictor of Quality of Life (QoL) in Women With Heavy Menstrual Bleeding (HMB) Under Dydrogesterone Treatment
Dydrogesterone is a retroprogesterone with a molecular structure similar to natural progesterone. As a C-21 steroid, it has a high affinity for progesterone receptors, a low antigonadotropic activity and antiestrogenic activity…
- Trial name
- NCT01647360
- Where
- 20 sites in Pakistan
- Volunteers
- 210 people
- Sponsor
- Abbott
Fertility Disorders
Human Chorionic Gonadotropin Versus Granulocyte Colony Stimulating Factor in Increasing Pregnancy Rate in ICSI
Intrauterine Granulocyte colony stimulating factor (GCSF) was compared with intrauterine Human Chorionic Gonadotropin (HCG) in increasing clinical pregnancy rate as a primary outcome and ultrasound imaging of gestational sac as a…
- Trial name
- NCT04606082
- Testing
- Granulocyte Colony Stimulated Factor, Human Chorionic Gonadotropins
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Breast Cancer, Cervical Cancer
Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 2
The purpose of this study is to increase early detection and prevention of breast and cervical cancer through education and navigation and to increase breast and cervical cancer screening and Human Papillomavirus (HPV)…
- Trial name
- SEMM2 (NCT06082882)
- Testing
- Education, Navigation to clinic
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Locally Advanced Cancer, Cervical Cancer
Carboplatin-Paclitaxel Adjuvant Chemotherapy in the Treatment of Locally Advanced Cervical Cancer
This is a mutlicentric, open-label non-randomized, national, 2-stage phase II trial to assess efficacy and safety of a weekly Carboplatin-Paclitaxel adjuvant chemotherapy after intensity modulated extended-field chemoradiation in…
- Trial name
- ACCRAPAN (NCT04016142)
- Testing
- Carboplatin-Paclitaxel adjuvant chemotherapy
- Where
- 6 sites in France
- Volunteers
- 21 people
- Sponsor
- Centre Oscar Lambret
PPH - Postpartum Hemorrhage, Eclampsia
Comparing Simulated Patients and Manikin Based Simulation in Obstetrics
The aim of this randomized study is to compare a live, trained simulated patient with a high-fidelity manikin in obstetric emergency team training using two standardized scenarios.
- Trial name
- NCT07857551
- Testing
- Trained, standardized patient, MamaAnne Patient Simulator
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Postpartum Hemorrhage
Excellent BRASSS-V Drape™ Versus Indirect Measurement Protocol for Measurement of Postpartum Blood Loss
Postpartum hemorrhage is one of the most common causes of maternal mortality and serious maternal morbidity, especially in the developing world.
- Trial name
- NCT01885845
- Testing
- Excellent BRASSS-V Drape™., Indirect weight assesment of blood loss
- Where
- India
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Ovarian Neoplasms, Endometrial Neoplasms
A Study of PF-07260437 in Advanced or Metastatic Solid Tumors
A study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of PF-07260437, a B7-H4 x CD3 bispecific mAb, in participants aged ≥18 years of age with advanced or metastatic…
- Conditions
- Ovarian Neoplasms, Endometrial Neoplasms, Breast Neoplasms
- Trial name
- C4431001 (NCT05067972)
- Testing
- PF-07260437, B7-H4 IHC
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- Pfizer
Carcinoma, Cervix Carcinoma
Neoadjuvant Treatment of Neuroendocrine Cervix Carcinomar With Camrelizumab Combined With Etoposide and Cisplatin
This study is a single arm, exploratory clinical study aimed at evaluating the efficacy and safety of karelizumab combined with etoposide and cisplatin in the neoadjuvant treatment of neuroendocrine cervix carcinoma.
- Trial name
- NCT05910177
- Testing
- Karelizumab combined with etoposide and cisplatin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fujian Cancer Hospital
Solid Tumor
A Trial of Tisotumab Vedotin in Japanese Subjects With Advanced Solid Malignancies
Open Label Phase 1/2 Trial of Tisotumab Vedotin in Japanese Subjects with Advanced Solid Malignancies
- Trial name
- innovaTV 206 (NCT03913741)
- Testing
- tisotumab vedotin
- Where
- 8 sites in Japan
- Volunteers
- 23 people
- Sponsor
- Genmab
Cervical Cancer, High Grade Sil
Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.
Nearly 8 000 new cervical cancer cases are diagnosed in South Africa per year; many are still undiagnosed and about 50% of diagnosed cases succumb per year.
- Conditions
- Cervical Cancer, High Grade Sil, CIN2
- Trial name
- DiaVACCS (NCT02956031)
- Testing
- Screening, Colposcopy, LLETZ
- Where
- South Africa
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Pretoria
Uterine Cervical Neoplasms
Urinary and Vaginal HPV Testing in Cervical Cancer Screening
Cervical cancer, caused by high-risk human papillomavirus (HPV) infection, poses a problem worldwide as it is the fourth most common female cancer.
- Trial name
- NCT05065853
- Testing
- urine self-sampling group, clinician-collected cervical sample group
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Endometrial Cancer
The Use of a Novel Vaginal Speculum for Endometrial Biopsies
The objective of this clinical trial is to determine if a newly-designed and FDA-cleared vaginal speculum (the Bouquet Speculum) will provide better visualization of the cervical os, be easier and more efficient to use, provide…
- Trial name
- NCT07217353
- Testing
- Bouquet Speculum
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rocky Vista University, LLC