Clinical trials: Uterine Hemorrhage
Contraception
Mirena Extension Trial
The study is performed to assess if Mirena is effective and safe as a birth control method beyond 5 years of use. Further the menstrual blood loss (in women that had Mirena inserted for the indication heavy menstrual bleeding…
- Trial name
- MET (NCT02985541)
- Testing
- Levonorgestrel IUS (Mirena, BAY86-5028)
- Where
- 49 sites in United States
- Volunteers
- 364 people
- Sponsor
- Bayer
Menorrhagia, Endometrial Biopsy
Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy
The purpose of this study is to determine whether using Misoprostol vaginally before an office endometrial biopsy is performed, will make it easier, more successful and less painful to do the procedure.
- Conditions
- Menorrhagia, Endometrial Biopsy, Cervical Ripening
- Trial name
- NCT00953641
- Testing
- Misoprostol
- Where
- Canada
- Sponsor
- University of Saskatchewan
Postpartum Haemorrhage (PPH), PPH
EVE TRIAL , ALMA SYSTAM
abnormal bleeding after childbirth. This condition is called abnormal bleeding and becomes a condition known as postpartum hemorrhage (PPH) when worsens.
- Conditions
- Postpartum Haemorrhage (PPH), PPH, Postpartum Hemorrhage (Primary)
- Trial name
- EVE (NCT06646653)
- Testing
- Alma System
- Where
- 2 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- ResQ Medical Ltd
Uterine Atony
Novel Approach of Hayman Uterine Compression Sutures for Management of Severe Atonic Postpartum Hemorrhage: Three Vertical Sutures
Maternal deaths due to uterine atony bleeding are the leading causes of maternal death in our country and all over the world. In this respect, our clinic is among the clinics with the highest number of experience in our country…
- Trial name
- NCT04690153
- Testing
- Patients with three vertical Hayman Sutures
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pınar Yalcin bahat
Postpartum Hemorrhage, Simulation Training
Simulation for the Retention of Skills in the Management of Obstetric Hemorrhages
The aim of this study is to evaluate the retention of knowledge and skills after theory+simulation training versus theoretical training alone in postpartum haemorrhage immediately, 3 months and 6 months after training in South…
- Conditions
- Postpartum Hemorrhage, Simulation Training, Healthcare Providers
- Trial name
- SimHPP (NCT05979701)
- Testing
- Simulation training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université Evangélique enAfrique
Cesarean Section Complications
Tranexamic Acid for the Control of Blood Loss at Elective Cesarean Section
The aim of the study is to determine, out of two doses (a standard and a low dose) compared to placebo, the optimal and minimal dose of an intravenously administered single bolus of tranexamic acid(TA) to reduce blood loss when…
- Trial name
- NCT03710330
- Testing
- normal saline, 1gm tranexamic acid, 0.5 gm tranexamic acid
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Aswan University Hospital
Postpartum Hemorrhage, Pain
Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss.
- Trial name
- NCT01786330
- Testing
- Procare abdominal binder, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zachary Kuhlmann, DO
Postpartum Hemorrhage
EMG for Uterotonic Efficiency Estimation
Studies found conflicting results on efficacy of uterotonic agents used to prevent and treat uterine atony, the most common cause of postpartum hemorrhage.
- Trial name
- EMGPHP (NCT04201665)
- Testing
- Carbetocin, Oxytocin
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Postpartum Bleeding
Postpartum Uterotonic Administration
The investigators are planning to determine the effect of the timing of oxytocin administration on the amount of blood loss, necessity for additional medical or surgical interventions.
- Trial name
- NCT02495272
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Uterine Bleeding
The Effect of Cyclofem® for the Treatment of Irregular Uterine Bleeding in Implant Contraceptive Users
The purpose of this study is to determine that once-a-month injectable contraceptive( Cyclofem® ) has the effect on treatment of irregular uterine bleeding in implant contraceptive users or not.
- Trial name
- NCT03264781
- Testing
- Cyclofem
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Dysfunctional Uterine Bleeding
Misotac vs Combined Oral Contraceptive Pill in the Treatment of Symptomatic Isthmocele
Isthmocele is a growing concern as a cause of abnormal uterine bleeding, especially post menstrual bleeding which may be present in up to 82% of these cases (Iannone et al 2019).
- Trial name
- NCT04579965
- Testing
- medical treatment of isthmocele
- Volunteers
- 50 people
- Sponsor
- Mansoura University Hospital
Tranexamic Acid Administration, Postpartum Hemorrhage
Tranexamic Acid for Reducing Blood Loss in High-Risk Cesarean Delivery
This randomized study evaluated whether prophylactic tranexamic acid (TXA) reduces perioperative blood loss in women at increased risk of postpartum hemorrhage undergoing elective cesarean delivery.
- Conditions
- Tranexamic Acid Administration, Postpartum Hemorrhage, Blood Transfusion, Perioperative Blood Loss
- Trial name
- TXA (NCT07870499)
- Testing
- Tranexamic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Mert Yetgin
Heavy Menstrual Bleeding, Menorrhagia
Pretreatment With Norethindrone Acetate Prior to Levonorgestrel IUS Insertion for Heavy Menstrual Bleeding
Problematic uterine bleeding after the insertion of the LNG IUS is a well documented side effect. The levonorgestrel intrauterine system (LNG IUS) was approved for treatment of heavy menstrual bleeding (HMB) by the FDA in October…
- Conditions
- Heavy Menstrual Bleeding, Menorrhagia, Hypermenorrhea
- Trial name
- Mirena IUD (NCT01391052)
- Testing
- Norethindrone acetate pretreatment, No pretreatment
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Bilateral Uterine Artery Ligation, Intrapartum or Postpartum Hemorrhage
Bilateral Uterine Artery Ligation After Intrapartum or Postpartum Hemorrhage on Ovarian Reserve Markers and Pregnancy Outcome
The aim of this study is to assess the possible negative effects of uterine artery ligation on ovarian reserve markers and subsequent pregnancy outcomes
- Conditions
- Bilateral Uterine Artery Ligation, Intrapartum or Postpartum Hemorrhage, Ovarian Reserve Markers, Pregnancy Outcome
- Trial name
- NCT05647538
- Testing
- Bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Intrauterine Polyp
Darwish Test (Office Hysteroscopic Bubble Suction and Tubal Peristalsis) in Cases of Intrauterine Polyp(s)
Anatomic Fallopian tubal patency and physiologic patency testing are feasible via hystertoscopy. This study aims to test the impact of different types of intrauterine polyp(s) on Darwish test (office hysteroscopic bubble suction…
- Trial name
- NCT04367415
- Testing
- Darwish test for a free endometrial cavity, Darwish test for an endometrial cavity with endometrial polyps
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Woman's Health University Hospital, Egypt
Heavy Menstrual Bleeding
HMB- Data Collection Methods
This is an observational study to determine the effect of various treatments prescribed by healthcare providers for heavy menstrual bleeding on bleeding related quality of life (as measured by the Menstrual Bleeding…
- Trial name
- NCT02001324
- Testing
- Web-based data collection, Paper-based data collection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Endometrial Hyperplasia, Endometrial Cancer
Preliminary Study of Endometrial Hyperplasia Groundwork for a Study to Define Precursors of Endometrial Cancer
This study, conducted jointly by the National Cancer Institute and the Kaiser Permanente Center for Health Research Northwest (KPCHRN) in Portland, Oregon, will lay the groundwork for a future study to identify precursors of…
- Conditions
- Endometrial Hyperplasia, Endometrial Cancer, Postmenopausal Bleeding, Vaginal Bleeding
- Trial name
- NCT00339651
- Where
- United States
- Volunteers
- 745 people
- Sponsor
- National Cancer Institute (NCI)
Menorrhagia
Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding
To assess the efficacy of a levonorgestrel 52 mg intrauterine system as a treatment for heavy menstrual bleeding.
- Trial name
- NCT03642210
- Testing
- Levonorgestrel 52 mg intrauterine system
- Where
- 29 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Medicines360
Postpartum Hemorrhage
Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage During Cesarean Section
Cesarean section (CS) is one of the most frequently performed operative interventions worldwide [1]. Cesarean section rates increase each year throughout the world.
- Trial name
- NCT06765473
- Testing
- Misoprostol
- Volunteers
- 400 people
- Sponsor
- Assiut University
Post Partum Hemorrhage, Asphyxia; Fetal
Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in Nepal
Postpartum hemorrhage and birth asphyxia are the leading causes of maternal and neonatal mortalities worldwide. Prevention and adequate treatment are, therefore crucial.
- Conditions
- Post Partum Hemorrhage, Asphyxia; Fetal, Maternal-Fetal Relations
- Trial name
- SLAB (NCT06577922)
- Testing
- Establishment of a simulation lab and provision of simulation based trainings
- Where
- Nepal
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- One Heart Worldwide