Clinical trials: Uterus; Scar
Assessment of Uterine Healing
Preliminary Study of Uterine Healing After Caesarean Section: CLInico-ECHOgraphic and Anatomopathologic COrrelation
Caesarean section is one of the most common surgical procedures. The multiplication of uterine scars leads to an increase in complications and in particular those related to poor healing such as isthmocele or uterine rupture.
- Trial name
- COCLIECHO (NCT05785559)
- Testing
- uterine biopsies
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Transvaginal Ultrasound, Caesarean Section
Transvaginal Ultrasound Assessment of Caesarean Section Uterine Scar Closed by Single Versus Double Layer
This study aimed to evaluate uterine scar thickness and integrity using transvaginal ultrasonography in women randomly assigned to single versus double-layer closure of the uterine incision, with a comparison between the two…
- Conditions
- Transvaginal Ultrasound, Caesarean Section, Uterine Scar, Single Layer
- Trial name
- NCT07074522
- Testing
- Single-layer closure, Double-layer closure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Ultrasound Evaluation
Ultrasound Evaluation of Uterine Healing After Vaginal Repair of Cesarean Scar Defect (CSD)
Cesarean scar defect is one of the complications after cesarean section (CSD). CSD may be further caused many long term complications, such as abnormal uterine bleeding, infertility, uterine scar pregnancy and uterine rupture.
- Trial name
- CSD (NCT04786626)
- Testing
- Ultrasound evaluation
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness
Evaluation of Cesarean Scar After Three Different Uterine Closure Technis
The study compares three techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section.
- Conditions
- Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness, Cesarean, Residual Myometrial Thickness
- Trial name
- NCT03915847
- Testing
- Single layer closure, Double layer closure, Doble layer closure with trimming
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Uterus; Scar
Cesarean Scar Evaluation Using Saline Infusion Sonography in Women With Previous Pregnancy in Scar
Evaluation of cesarean scar using saline-infused sonography in women with history of cesarean scar pregnancy.
- Trial name
- NCT05672563
- Testing
- Saline infusion sonography for evaluation of cesarean scar
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Cesarean Section; Dehiscence
Mri in Evaluation of Cesarean Section Scar Niche
To evaluate cesarean section scar and the lower uterine segment in non pregnant woman by MRI to : 1. Assess the clinical symptoms like postmenstrual spotting or prolonged menstrual bleeding, dysmenorrhea, chronic pelvic pain and…
- Trial name
- NCT03911622
- Testing
- MRI
- Volunteers
- 30 people
- Sponsor
- Assiut University
Caesarean Scar Defect
Sparse Uterine Closure in Cesarean Section
The existence and the characteristics of a wedge- shaped defect in the uterine incision scar were demonstrated by radiologic, ultrasonographic, endoscopic and histologic methods by various authors.
- Trial name
- NCT03930134
- Testing
- sparse uterine suture, one layer uterine closure
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Cesarean Section Complications, Abnormal Uterine Bleeding
Combined Hystroscopic and Laparoscopic Repair of CS Scar Disorder
Combined hystroscopic and laparoscopic repair of symptomatic uterine Niche as new technique to maximize resolution of symptoms after niche repair with concomitant increase in RMT
- Trial name
- NCT07183501
- Testing
- Combined hystroscopic and laparoscopic repair
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Caesarean Scar Pregnancy
UACE Followed by Uterine Suction Curettage for the Treatment of Caesarean Scar Pregnancy
The purpose of this study is to determine whether UACE(uterine artery chemo-embolization) followed by suction curettage under the guidance of ultrasonography or hysteroscopy can decrease complications in the treatment of…
- Trial name
- UACECSP (NCT02357095)
- Testing
- monitoring
- Volunteers
- 144 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Pregnancy, Cesarean Section
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Conditions
- Pregnancy, Cesarean Section, Uterine Rupture
- Trial name
- NCT00517140
- Testing
- Repeat Caesaen section, vaginal delivery
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Hospital Authority, Hong Kong
Cesarean Section; Dehiscence, Cesarean Scar Niche
Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section
The aim of this study is to evaluate the efficacy of alpha lipoic acid on uterine scar healing after cesarean section by using saline contrast sonohysterography
- Trial name
- NCT03257514
- Testing
- alpha lipoic acid drug (thioctic acid acid)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Induction of Abortion, Scarred Uterus
Laminaria Japonicum Followed by Misoprostol Versus Misoprostol Alone for Mid-Trimester Abortion Induction in Scarred Uterus
The goal of this clinical trial is to compare the induction-to-abortion time interval between women receiving Laminaria tent followed by misoprostol and those receiving misoprostol alone for mid-trimester abortion induction in…
- Trial name
- Obstetrics (NCT07465016)
- Testing
- Misoprostol ( Cytotec) 200 microgram a tablet, Laminaria Tent
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Pavly Maged Jimmy Fouad
Cesarean Section Complications, Cesarean Wound Disruption
Cesarean Scar Defect Formation After First Cesarean Section.
This study is a prospective observational study which will monitor how cesarean section in the first pregnancy will develop a cesarean scar defect.
- Conditions
- Cesarean Section Complications, Cesarean Wound Disruption, Cesarean Wound; Dehiscence
- Trial name
- NCT03966001
- Testing
- Transvaginal sonography at six months after cesarean section, Transvaginal sonography at twelve months after cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Cesarean Scar Defect (Isthmococele)
Incision-Parallel Double-Layer Non-Locking Versus Single-Layer Locked Uterine Closure After Primary Caesarean Delivery: A Randomized Controlled Trial
This randomized controlled trial was conducted to compare two uterine closure techniques in women undergoing primary cesarean delivery.
- Trial name
- NCT07841028
- Testing
- Single-Layer Locked Uterine Closure, Double-Layer Incision-Parallel Nonlocking Uterine Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Onur Karaaslan
Appropriate Diagnostic Criteria of Uterine Niche With Detection of Prevalence , Risk Factors and Associated Symptomes
Prevalence and Risk Factors of Uterine Niche Following Different Caesarean Section Techniques:a Hospital Based Study
The primary objective of this study is to institute clically relevant and objective sonographic criteria for the diagnosis of ceasearan section scar defect(CSSD) once the appropriate diagnostic criteria are established the…
- Trial name
- NCT04933032
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Niche
Niche In CEsarean Scar Trial (NICEST)
Rationale: Cesarean delivery (CD) rates are increasing rapidly worldwide. The consequences of cesarean section not only affect the next pregnancies such as uterine rupture or malplacentation but also cause many gynecological…
- Trial name
- NCT05312775
- Testing
- Double-layer uterine closure, Single-layer uterine closure
- Where
- Vietnam
- Volunteers
- 938 people, healthy volunteers welcome
- Sponsor
- Nguyen Thi Thu Ha
Uterine Scar, Cesarean Section Complications
Single or Double-layer Uterine Closure Techniques
There are different surgical techniques of uterine closure during cesarean. A growing data has suggested that the closure technique has an effect on uterine scar healing.
- Conditions
- Uterine Scar, Cesarean Section Complications, Cesarean Section; Dehiscence
- Trial name
- NCT03629028
- Testing
- Residual myometrium thickness, Niche Presence, Adjacent myometrium thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Safak Baran Yilmaz
Laparoscopy, Tissue Adhesion, Surgery-Induced
The Efficacy and Safety of Medicurtain® in Patients With Total Laparoscopic Hysterectomy (Pivotal Study)
This study was designed to assess the safety and efficacy of MEDICURTAIN. Patients who underwent total laparoscopic hysterectomy were randomly assigned either into Medicurtain® treatment group or non-treatment control group.
- Conditions
- Laparoscopy, Tissue Adhesion, Surgery-Induced, Leiomyoma of the Uterine Body
- Trial name
- NCT04672421
- Testing
- Medicurtain®
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Uterine Scar Remodeling
Cesarean-scar Thickness and Closure Technique
The aim of this trial is the surgical method in cesarean deliveries, especially the uterotomy closure technique.
- Trial name
- NCT02338388
- Testing
- cesarean section technique
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Christian Bamberg