Clinical trials: Uveitis; Posterior, Disorder
Uveitis, Posterior
Role of OCT & OCT Angiography in Patients With Posterior at the Uveitis Clinic of Assiut University Hospital.
OCT angiography is a recent evaluation of OCT technology which combines the structural assessment of ocular tissues obtained by OCT image with visualization of blood flow within the vessels in imaged area.
- Trial name
- NCT06743906
- Volunteers
- 25 people
- Sponsor
- Assiut University
Uveitis, Posterior, Vasculitis Retinal
Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis
The purpose of this study is to evaluate the short- and long-term efficacy and safety of Acthar for the treatment of adults with non-infectious retinal vasculitis.
- Trial name
- NCT03066869
- Testing
- H.P. ACTHAR GEL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ocular Immunology and Uveitis Foundation
VKH Syndrome
Oral Prednisolone Versus Posterior Sub-Tenon Triamcinolone for Acute Ocular VKH
Vogt-Koyanagi-Harada (VKH) disease is a rare autoimmune disorder characterized by bilateral ocular inflammation that may lead to serous retinal detachment and permanent visual impairment if not promptly treated.
- Trial name
- VKH-OC (NCT07405489)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Vitiligo, Chorioretinopathy
Ocular Changes in Vitiligo Patients on Therapy
Vitiligo patients on systemic and local therapy may have some ocular adverse effects associated with the disease and its therapy.
- Conditions
- Vitiligo, Chorioretinopathy, Chorioretinitis
- Trial name
- NCT05335746
- Testing
- Optical coherence tomography angiography (OCT-A)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Choroidal Neovascularization, Punctate Inner Choroidopathy
Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor
To evaluate the long-term outcome of active choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) after anti-vascular endothelial factor treatment.
- Trial name
- NCT03793400
- Testing
- Bevacizumab Injection
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Changhua Christian Hospital
Uveitis
A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis
The purpose of this study is to evaluate the long term efficacy and safety of adalimumab participants with non-infectious intermediate-, posterior- or pan-uveitis.
- Trial name
- VISUAL III (NCT01148225)
- Testing
- adalimumab
- Volunteers
- 424 people
- Sponsor
- AbbVie
Spondylarthritis, Uveitis, Anterior
Observational Prospective Turkish Inception Cohort of Uveitis and Spondyloarthritis
Spondyloarthritis (SpA) encompasses a group of inflammatory rheumatic diseases characterized by axial and/or peripheral arthritis, along with extra-articular manifestations such as enthesitis, dactylitis, uveitis, and skin…
- Trial name
- OPTICUS (NCT06720376)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Intermediate Uveitis, Posterior Uveitis
Retisert and Cataract Surgery in Patients With Severe Uveitis
To review chart data at the Duke Eye Center and determined whether a 3-year fluocinolone acetonide sustained drug delivery system (FA) safely suppressed postoperative inflammation when combined with phacoemulsification and…
- Trial name
- NCT00570830
- Testing
- Retisert (fluocinolone acetonide implant)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Uveitis, Posterior, Uveitis, Intermediate
Safety and Preliminary Efficacy Study of V404 PDS in Uveitis
This study is intended to evaluate the safety of V404 PDS in patients with chronic non-infectious uveitis. Secondarily, the study will evaluate whether V404 PDS can provide clinically measurable benefit over an extended period of…
- Trial name
- NCT02125266
- Testing
- V404
- Where
- 5 sites in United States
- Volunteers
- 7 people
- Sponsor
- Forsight Vision4
Non Infectious Uveitis
A Proof-of-concept Trial to EvaluAte the efficaCy and Safety Of Cell Therapy TRX103 in Patients With Active, Non-infectious Uveitis
The purpose of this Phase 1, first in uveitis open-label study is to assess the safety and tolerability of TRX-103 in patients with non infectious uveitis (NIU).
- Trial name
- PEACOCX (NCT07427628)
- Testing
- TRX103
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Quan Dong Nguyen
Subjects Clinically Suspected an Active Source of Toxoplasmosis Chorioretinitis Infection
Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis
Toxoplasmosis affects one to two newborn each 10000 births. Among them, 1 to 2 % develop learning disabilities or die, and 4 to 27 % develop a chorioretinitis sometimes leading to an amblyopia responsible for visual impairment.
- Trial name
- BIOLUVE (NCT02843438)
- Testing
- Fluorescein angiography, Dilated fundus examination, Toxoplasmosis serology
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Grenoble
Uveitis, Cataract
Outcome of Different IOLs in Patients With and Without Uveitis
Cataract, is a clouding of the lens in the eye gradually leading to reduction of the visual acuity. In most cases it can be managed with surgery, removing the own lens and replacing it with an artificial lens, intraocular lens…
- Conditions
- Uveitis, Cataract, Inflammation, Posterior Capsule Opacification
- Trial name
- NCT02975895
- Testing
- Hydrophobic IOL: Vivinex (HOYA), Hydrophilic IOL: INCISE (Bausch+Lomb)
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Vastra Gotaland Region
Uveitis, Posterior, Uveitis, Intermediate
Ozurdex Monotherapy Trial
This study will investigate the efficacy and safety of OZURDEX® (dexamethasone intravitreal implants; DEX, Allergan, Inc. Irvine, CA) as monotherapy for the treatment of non-infectious intermediate-, posterior- or panuveitis.
- Conditions
- Uveitis, Posterior, Uveitis, Intermediate, Panuveitis
- Trial name
- OM (NCT05101928)
- Testing
- Ozurdex 0.7mg Ophthalmic Implant, Prednisone
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Uveitis
HUMIRA® Long-term Treatment in Patients With Non-infectious Intermediate-, Posterior-, or Pan-uveitis
This study evaluates the long- term safety and effectiveness of adalimumab in participants with non-infectious intermediate-, posterior-, or pan-uveitis in daily practice in Japan.
- Trial name
- NCT02916017
- Where
- 39 sites in Japan
- Volunteers
- 259 people
- Sponsor
- AbbVie
Uveitis, Posterior, Uveitis, Anterior
Ixekizumab for the Management of Refractory Non-Infectious Uveitis: A Proof-of-Concept Study
The objective of this study is to explore the efficacy of ixekizumab in treating patients with a diagnosis of non-infectious intermediate, posterior, panuveitis, or chronic steroid-dependent anterior uveitis who had failed…
- Conditions
- Uveitis, Posterior, Uveitis, Anterior, Uveitis, Intermediate, Panuveitis
- Trial name
- NCT06085079
- Testing
- Ixekizumab Prefilled Syringe
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye Research and Surgery Institution