Clinical trials: VALİDİTY
Healthy
Oxygen Reserve Index (ORi) Validation of INVSENSOR00025
ORi is a unitless index that could help clinicians with their assessments or normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03628898
- Testing
- INVSENSOR00025
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Allergy to House Dust, Allergy Pollen
Validation and Reproducibility of S.P.A.T. With Allergens
To improve accuracy and take out human error opportunities, Hippo Dx developed S.P.A.T., an automated skin prick test. This study will provide a comparison between manual and automated skin prick test in allergic and non-allergic…
- Trial name
- NCT05824637
- Testing
- Skin Prick Automated Test, Skin Prick Manual Test
- Where
- Belgium
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hippocreates
Fever
Calibration and Validation of the Masimo Temperature Device in Febrile Patients
The goal of this clinical trial is to test the performance of the Masimo noninvasive temperature device in patients with fever. The main question it aims to answer is whether the Masimo temperature device is comparable to…
- Trial name
- NCT05674344
- Testing
- Masimo Temperature device
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Masimo Corporation
Myelodysplastic Syndromes, Leukemia Myeloid Acute
Validation of a Comprehensive Health Status Assessment Scale in Elderly Patients (≥ 65 Years) With Hematological Malignancies
The elderly comprise the most prevalent population in oncology practice. The available evidence suggests that old patients are undertreated patients, mainly because of their advanced age, regardless of whether they are highly…
- Conditions
- Myelodysplastic Syndromes, Leukemia Myeloid Acute, Multiple Myeloma, Leuklemia, Lymphocytic, Chronic
- Trial name
- GAH (NCT02164071)
- Testing
- Geriatric Assessment of Health Status Scale administration
- Where
- 22 sites in Spain
- Volunteers
- 363 people
- Sponsor
- Celgene
Device Validation of In-vivo Performance
Trima Non-DEHP Leukoreduced Red Blood Cell In Vivo Recovery Study
This is an in vivo 24-hour in-vivo recovery study of leukoreduced red blood cells (RBCs) collected on the Trima Accel System using Non-DEHP disposable sets and stored for 42 days.
- Trial name
- NCT06602804
- Testing
- Trima Accel Auto RBC Collection
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Terumo BCT
Obstructive Sleep Apnea (OSA)
Validation of HC250 and HC240 Series.
This study is designed to determine the effectiveness of two different CPAP devices. One a standard CPAP which has the ability to store comprehensive compliance and efficacy data and the second a auto adjusting CPAP which uses…
- Trial name
- NCT00739011
- Testing
- SleepStyle 254/244 CPAP series CPAP humidifier
- Where
- 2 sites in New Zealand
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Brain Injuries, Traumatic
Brain Oximeter Calibration and Validation Study
The purpose of the study is to calibrate and to validate the accuracy of the oximeter with an estimate of brain oxygen levels assessed by measuring arterial and internal jugular vein blood oxygen saturations.
- Trial name
- TPOT (NCT05397704)
- Testing
- brain pulse oximeter
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cyban Pty Ltd
Lung Cancer
T790M Plasma Testing Methodology Comparison and Clinical Validation
The aim of this study is to evaluate concordance of T790M mutation plasma testing between the Cobas test and each of other platforms: Super-ARMS, digital PCR or NGS.
- Trial name
- ADELOS (NCT02997501)
- Testing
- T790M+ Testing, Baseline Visit Blood & Urine Testing, Baseline ECG
- Where
- 7 sites in China
- Volunteers
- 256 people
- Sponsor
- AstraZeneca
COVID-19
Validation of TERA Bio Station T101 of COVID-19 Tested Population.
TERABio Ltd. has developed a rapid screening tool intended to determine if a tested individual is COVID-19-free (Negative to COVID-19).
- Trial name
- NCT05088902
- Testing
- TERABio Ltd.
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tera Group
Gastric Cancer
Multi-Omics Noninvasive Inspection of TumOr Risk for Gastric Cancer
This is a prospective, case-control study intended to develop and validate a blood-based multi-omics assay and computational model for early detection of gastric cancer.
- Trial name
- MONITOR- GAC (NCT04947995)
- Testing
- ctDNA multi-omics test
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- GeneCast Biotechnology Co., Ltd.
Alzheimer Disease
Multi-parameter Diagnostic Blood Test for the Diagnosis of Alzheimer's Disease
The purpose of this study is to validate a diagnostic test that combines different blood markers to identify and correctly classify patients with Alzheimer's disease (AD) compared to individuals with behavioural variant…
- Trial name
- RH-VAL (NCT02409030)
- Where
- 16 sites in Belgium, France and 1 more
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Raman Health Technologies, S.L.
Depression - Major Depressive Disorder, Anxiety
AcceXible Speech-Based Screening for Depression and Anxiety in University Students (BUAP, Mexico)
Major depressive disorder (MDD) and anxiety are increasingly prevalent among university student populations, yet early detection remains reliant on psychometric instruments tied to diagnostic criteria (e.g., PHQ-9, GAD).
- Trial name
- NCT07553130
- Testing
- AcceXible
- Where
- Mexico
- Volunteers
- 785 people, healthy volunteers welcome
- Sponsor
- Accexible
A Minimum of 30 Adults, Ages 18 Years and Older
Respiratory Rate Validation Study - RS001.2 Respiree Cardio-Respiratory Monitor
The purpose of this study is to conduct a Respiratory Rate accuracy validation comparing the RS001.2 Respiree Cardio-Respiratory Monitor to the Reference, an FDA cleared End Tidal Carbon Dioxide monitor (GE Datex-Ohmeda).
- Trial name
- NCT05210712
- Testing
- RS001.2 Respiree Cardio-Respiratory Monitor
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Respiree Pte Ltd
SARS-CoV-2 Infection, Influenza A
SARS-CoV-2 and Influenza A/B in Point-of-Care and Non-Laboratory Settings
The Metrix COVID/Flu Test will be evaluated for use in Point-of-Care and Non-Laboratory settings in a home testing environment utilizing the clinical study design described herein.
- Conditions
- SARS-CoV-2 Infection, Influenza A, Influenza B
- Trial name
- NCT06191393
- Testing
- Aptitude Medical Systems Metrix COVID/Flu Test
- Where
- 3 sites in United States
- Volunteers
- 614 people
- Sponsor
- Aptitude Medical Systems
Colonic Polyp, Colonic Neoplasms
Validation of Aer-O-Scope Colonoscope System Cecal Intubation
61 subjects (male or female) between the ages of 45 and 75 will undergo colonoscopy. The primary outcome is Cecal Intubation
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Diseases, Colon Adenoma
- Trial name
- NCT03949777
- Testing
- Aer-O-Scope Colonoscopy
- Where
- Israel
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Blood Pressure, Hypertension
Validation Study of CART BP as a Wearable Cuffless Blood Pressure Monitor
This study aims to evaluate the accuracy of the CART BP, a medically approved ring-type blood pressure monitor, in comparison to the traditional auscultatory method using a dual-head stethoscope.
- Conditions
- Blood Pressure, Hypertension, Blood Pressure, High, Blood Pressure, Low
- Trial name
- NCT06513975
- Testing
- CART BP, sphygmomanometer
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Compartment Syndromes
SWISS_EVIDENCE - Compartment Compressibility Monitoring Using CPM#1
Compartment syndrome is a very serious musculoskeletal disorder, which can lead to potentially devastating consequences, such as limb amputation and life-threatening conditions.
- Trial name
- NCT05367921
- Testing
- Measurement of compartment compressibility
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Compremium AG
Clostridium Difficile Infection
Validation of the GenePOC CDiff Assay for the Detection of the Toxin B Gene From Toxigenic Clostridium Difficile Strains
The primary purpose of this clinical investigation is to verify the performance of the GenePOC CDiff test on the GenePOC instrument.
- Trial name
- NCT02968758
- Testing
- Comparison between GenePOC PCR and Reference Method
- Where
- 7 sites in United States, Canada
- Volunteers
- 2,461 people
- Sponsor
- Meridian Bioscience, Inc.
Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Caesar Foot Take-Home Validation Testing
The rationale for this study is to conduct a take-home clinical trial to evaluate the impact of the bimodal Caesar foot in a real-world environment.
- Trial name
- NCT07075198
- Testing
- Caesar Foot
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Liberating Technologies, Inc.
Parkinson Disease
Objective Quality of Life Detection Validation
The purpose of this research study is to: Collect data to use in the development of a standardized tool for identifying patients with Parkinson's disease (PD) who would benefit from advanced therapies (AT) such as deep brain…
- Trial name
- NCT04121793
- Testing
- Kinesia 360 and Smartphone sensors
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.