Clinical trials: VALİDİTY
Cancer
Validation of FACBC for Detection of Metastasis Among High-risk Prostate Cancer Patients With Presumed Localized Disease
This study is for patients who have a high risk of metastatic prostate cancer (cancer that has spread outside of the prostate) who are going to have radical prostatectomy.
- Trial name
- EDRN-FACBC (NCT03081884)
- Testing
- FACBC PET-CT Imaging
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Emory University
Mortality Rate
Machine Learning Platforms to Predict 30-day Mortality After Emergency Laparotomy
This study seeks to utilise retrospective patient data to train machine learning algorithms to predict the short term mortality and morbidity after an emergency laparotomy.
- Trial name
- NCT05828914
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The University of Hong Kong
Non-alcoholic Fatty Liver Disease (NAFLD)
Validation Study of the Velacur System in Comparison to MRE & MRI-PDFF in Patients With (Suspected) Liver Disease
The goal of this open-label, non-randomized, prospective study is to compare Velacur and MRE in all sexes, 18-80 years old with Non-Alcoholic Fatty Liver Disease (NAFLD).
- Trial name
- NCT05908006
- Testing
- Velacur
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- GI Alliance
Obstructive Sleep Apnea
Validation of the ApneaLink Sleep Screener for Obstructive Sleep Apnea (OSA)
The primary endpoints for this study are that the AL validation will 1) achieve a sensitivity of greater than 80% for AHI values greater than or equal to 15, and 2) demonstrate a correlation coefficient of r=0.75 indicating…
- Trial name
- NCT00354614
- Testing
- ApneaLink Sleep Screener
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- ResMed
Subjects at High Risk of Lung Cancer Due to Smoking
Continuous Observation of Smoking Subject
The purpose of this study is to offer annual low-dose spiral CT radiological examination for 5 years to 5000 volunteers from the general population who are considered to be at high risk of developing lung cancer.
- Trial name
- COSMOS (NCT01248806)
- Testing
- Low dose CT scan
- Where
- Italy
- Volunteers
- 5,203 people
- Sponsor
- European Institute of Oncology
Idiopathic Pulmonary Fibrosis, Activity, Motor
Londrina Activities of Daily Living Protocol in Idiopathic Pulmonary Fibrosis Patients
The Londrina Activities of Daily Living Protocol was first developed for Chronic Obstructive Pulmonary Disease patients and was found to be valid and reliable, but there is no validity and reliability study of the Londrina…
- Trial name
- NCT06049004
- Testing
- Activities of Daily Living Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Katip Celebi University
Low Back Pain
Development and Validation of the Italian Version of the Waddell Chronic Disability Index for People With Low Back Pain
This prospective observational study aims to develop and validate an Italian version of the Waddell Disability Index (WDI-I), a self-administered questionnaire designed to assess disability related to chronic low back pain.
- Trial name
- NCT07413107
- Where
- 2 sites in Italy
- Volunteers
- 115 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Stroke
Validation Study of SCALA, Scale for Lateropulsion
Development and clinical validation of SCALA, a new rating scale for lateropulsion after stroke. A monocentric clinical study including 78 post-stroke individuals and 30 patients without stroke and/or healthy volunteers.
- Trial name
- SCALA (NCT03077399)
- Testing
- SCALA
- Where
- France
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Patient Safety, Intraoperative Complications
Validation Study of ClassIntra®
Whereas there are several validated systems for reporting postoperative complications, there are only a few and not prospectively validated systems for reporting intraoperative complications.
- Conditions
- Patient Safety, Intraoperative Complications, Postoperative Complications, Risk Management
- Trial name
- ClassIntra® (NCT03009929)
- Testing
- Observational study
- Where
- 18 sites in United States, Australia and 10 more
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Flutter Typical
Validation of Beat-to-beat Wavefront Direction Using Omnipolar Mapping
To validate omnipolar mapping in a well-described circuit within the heart (Atrial Flutter) and compare it with the gold standard of Local Activation Time (LAT) mapping during routine, clinically indicated procedures of Atrial…
- Trial name
- ATOM (NCT04900831)
- Testing
- Omnipolar Eletroanatomical mapping
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College Healthcare NHS Trust
Idiopathic Pulmonary Fibrosis
Study to Test the Validity of the Treatment of Idiopathic Pulmonary Fibrosis With Cotrimoxazole
First study to test the validity of the treatment of idiopathic pulmonary fibrosis, which causes inflammation and fibrosis (scarring) of the lung tissue, with cotrimoxazole.
- Trial name
- TriSulfa-FPI (NCT01777737)
- Testing
- Cotrimoxazole
- Where
- Spain
- Volunteers
- 3 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Lung Cancer
Identifying Biomarkers for Lung Cancer Using Tissue Samples From Patients With Lung Cancer and From Healthy Participants
RATIONALE: Studying samples of tissue, blood, sputum, and urine from patients with lung cancer and from healthy participants in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers…
- Trial name
- NCT00899028
- Testing
- comparative genomic hybridization, fluorescence in situ hybridization, gene expression analysis
- Where
- 4 sites in United States
- Volunteers
- 689 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Sepsis
Derivation and Validation of a Prognostic Model for Septic Patients at Hospital Admission
The aim of the present study is to develop a prognostic tool to assess the risk of dead and major complications in patient admitted to hospital for infection.
- Trial name
- NCT03601767
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Azienda Ospedaliera San Paolo
Chinese Version, Fibromyalgia
Chinese Version of Fibromyalgia Criteria and Severity Scales Study
Up to now, there is no Chinese version of fibromyalgia diagnosis criteria and severity assessment scales. The aim of this study is to translate, adapt, and validate the Chinese version of the 2011 modification of the 2010 ACR…
- Conditions
- Chinese Version, Fibromyalgia, Diagnosis, Fibromyalgia Impact Questionnaire
- Trial name
- NCT03381131
- Where
- China
- Volunteers
- 327 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Lymphedema Arm, Lymphedema
Lymphedema Sensor Technology Development Study
The goal of this clinical trial in adult patients diagnosed with upper extremity lymphedema is to test the safety and effectiveness of small, wearable sensors that may be able to measure lymphedema.
- Conditions
- Lymphedema Arm, Lymphedema, Cancer
- Trial name
- NCT06778837
- Testing
- Wearable devices to detect lymphedema
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Heart Valve Diseases
Clinical Validation of Portable Electronic Stethoscope for Detecting VHD
The goal of this observational study is to evaluate accuracy of portable electronic stethoscope and machine learning-based diagnostic algorithms for detecting the disease in people with valvular heart disease and healthy…
- Trial name
- NCT07568795
- Testing
- BPM Core
- Where
- Hong Kong
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Esophageal Cancer
UICC Classification of Esophageal Cancer
Background. The aim of our study was to investigate the ability of the Seventh edition of the classification by the International Union Against Cancer (UICC) to identify patients at higher risk and to predict the overall survival…
- Trial name
- NCT01770275
- Where
- Germany
- Volunteers
- 605 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Athlete, Eating Disorder Prevention
Cross-cultural Adaptation and Validation of the French Version of the Athletic Disordered Eating Scale (ADE)
Assessing disordered eating is crucial in athlete health monitoring. However, existing tools are not tailored to athletes' specific needs. In 2024, Buckley et al.
- Conditions
- Athlete, Eating Disorder Prevention, Eating Disorders Symptoms
- Trial name
- ADE-Fr (NCT07617701)
- Testing
- The French version of the Athletic Disordered Eating (ADE-Fr) Scale
- Where
- France
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Dental Implant-Abutment Design
Validation Use of Implants and Abutments With Biologically Oriented Preparation Technique
This randomized clinical trial aims to validate and to establish indications for using implants with biological oriented preparation technique (I.B.O.P.T.) for implant supported prosthetic treatment as an option looking for…
- Trial name
- NCT05051839
- Testing
- Implant surgery and restoration
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Healthy Patients
Automated Caries Detection Using a 3D Intraoral Scanner. An in Vivo Validation Study.
This in vivo study with in vitro validation assessed four different algorithms (ALG1-ALG4) implemented in the intraoral scanner system for automated caries detection and classification.
- Trial name
- NCT04812405
- Testing
- Trios4
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens
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