Clinical trials: VALİDİTY
Opioid Use Disorder
OUD (Opioid Use Disorder) Target Trial
In this research study the investigators will work with 80-participants with opioid use disorder who are starting treatment with the medication buprenorphine and are trying to quit using opioids.
- Trial name
- NCT06585709
- Testing
- Active repetitive Transcranial Magnetic Stimulation (rTMS), High Ventral Striatal Reactivity, Low Ventral Striatal Reactivity
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University
Postoperative Quality of Recovery in the Postanesthesia Care Unit
Validation of the Quality of Recovery Questionnaire for the Postanesthesia Care Unit (QoR-PACU)
Quality of recovery after surgery and anesthesia is an important endpoint in perioperative medicine. Several questionnaires have been developed that assess the patient's perception on postoperative recovery at 24 h after surgery.
- Trial name
- NCT04528537
- Testing
- questionnaire
- Where
- Germany
- Volunteers
- 375 people
- Sponsor
- Marlene Fischer
Peripheral Artery Disease (PAD)
Validity and Reliability of the 6-minute Stepper Test in Patients With Peripheral Artery Disease
Hemodynamic dysfunction and decreased blood flow to the extremities negatively affect patients' muscle oxygenation, balance, claudication pain, lower extremity muscle strength, and arterial stiffness.
- Trial name
- NCT07169045
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Abdominal Aortic Aneurysms
Validation of Fenestrations Positioning by Numerical Simulation
Fenestrated endovascular repair (FEVAR) is nowadays a recognized option to treat juxtarenal, pararenal or suprarenal abdominal aortic aneurysms in patients at high risk for conventional repair.
- Trial name
- FenSim (NCT03469245)
- Testing
- numerical simulation
- Where
- 9 sites in Austria, France and 3 more
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Allergic Rhinitis
Validation of Laser Doppler Flowmetry to Identify Allergic Rhinitis Patients With Pharmacogenetic Alterations in Histamine Metabolism
The hypothesis to be proven is that histamine iontophoresis with measurement of microvascular blood flow by laser Doppler flowmetry can be used as a reliable marker to characterize the normal microvascular cutaneous response to…
- Trial name
- NCT00362999
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Children's Mercy Hospital Kansas City
Healthy Adult, Sleep Apnea
Oura Ring OA15 Validation
The current study intends to collect data from Oura Ring time-locked to ground truth medical sleep diagnostic gold-standard polysomnography (PSG) for product research and development, investigational algorithm validation, and…
- Trial name
- NCT07908199
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ouraring Inc.
Quantitative Validation for Ventricular SPECT Imaging
Validation of Quantitative Ventricular Function Imaging Single Photon Emission Tomography (Spect)Using the D-SPECT Cardiac Camera
The purpose of this study is to validate the use of DSPECT camera for the performance of quantitative spect ventricular function imaging by comparison to a validated procedure performed on standard nuclear cameras.
- Trial name
- NCT01296737
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Spectrum Dynamics
Heparin-induced Thrombocytopenia
Heparin-Induced Thrombocytopenia: Development and Validation of a Predictive Clinical
Although Heparin-induced thrombocytopenia (HIT) is a rare complication of heparin treatment, it results in a high rate of morbidity and mortality, the cumulative rate of thrombosis recurrence, amputation and death approaching 52…
- Trial name
- Score-TIH (NCT00748839)
- Where
- 27 sites in France
- Volunteers
- 2,700 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infection
Identigene STD Test Collection Kit Validation Study
The overall goal of the present study is to provide evidence of concordant test results using the Identigene STD Test Collection Kit for self-collection and transport of specimens to a qualified testing laboratory.
- Trial name
- NCT01471392
- Testing
- STD Diagnostic Kit (Identigene)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Identigene
Prostate Cancer, Active Surveillance for Prostate Cancer
Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial)
The CHAS3 trial studies whether the Stockholm3 blood test can reliably detect if prostate cancer becomes more aggressive in men who are being carefully monitored instead of treated right away (active surveillance).
- Trial name
- CHAS3 (NCT07478536)
- Testing
- Stockholm3
- Where
- Switzerland
- Volunteers
- 350 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lung Transplant; Complications
Validation of the Respiratory Function of Pulmonary Transplants to Anticipate Unplanned Hospitalizations
Acute cellular and/or humoral rejection and early graft infections after pulmonary transplant (<2.5 years) are common and can lead to chronic dysfunction of the transplanted organ or Chronic Lung Allograft Dysfunction, CLAD.
- Trial name
- TRANSADOM (NCT03368365)
- Testing
- Ventilotel ®
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
ADHD - Attention Deficit Disorder With Hyperactivity
Sustained Endogenous Attention Deficits in Attention Deficit Hyperactivity Disorder
Subjects with ADHD may exhibit deficits in sustained internal attention. The "Sustained-Paced Finger Tapping" test was recently developed and experimentally used in international literature to assess sustained internal attention…
- Trial name
- NCT06900400
- Testing
- Sustained-Paced Finger Tapping" (Petilli et al., 2018)
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Overweight or Obese Adults
The 6-minute Pegboard and Ring Test in Overweight and Obese Individuals
The aim of our study is to investigate the validity and reliability of the 6-minute pegboard and ring test in overweight and obese individuals.
- Trial name
- NCT06742112
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Rectal Cancer
Radiographic Validation of the Inferior Mesenteric Artery Tie Level in Rectal Cancer Surgery
The inferior mesenteric artery is the feeding vessel for tumours in the rectum. When performing surgery for these tumours, the surgeon can cut the vessel close to the aorta or after the vessel bifurcates to the superior rectal…
- Trial name
- RAVAL (NCT03875612)
- Where
- 2 sites in Sweden
- Volunteers
- 98 people
- Sponsor
- Umeå University
Temporomandibular Disorders (TMDs), Kinesiophobia
The Italian Version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD)
This observational, cross-sectional study aims to translate, culturally adapt, and psychometrically validate the Italian version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD-ITA).
- Trial name
- TSK-TMD-ITA (NCT07750509)
- Volunteers
- 250 people
- Sponsor
- Alessandro Aquino
Obesity and Obesity-related Medical Conditions, Diabetes
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research…
- Conditions
- Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure
- Trial name
- VALD (NCT07083557)
- Testing
- Endothelial cell collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer
Validation
Prospective Validation of the ROX Index
We recently described the ROX index, defined as the ratio of SpO2/FIO2 to respiratory rate that outperformed the diagnostic accuracy of the two variables separately.
- Trial name
- NCT02845128
- Where
- 5 sites in France, Spain
- Volunteers
- 191 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Spondylolisthesis
Validation of Appropriateness Criteria for the Surgical Treatment of Lumbar Degenerative Spondylolisthesis
The main objective of this study is the external validation of the appropriateness criteria for the surgical treatment of Lumbar Degenerative Spondylolisthesis.
- Trial name
- NCT02966639
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obstructive Sleep Apnea Syndrome, Obesity
Portable Monitoring Device for the Diagnosis of Sleep Apnea in Obese Patients
Introduction The portable monitoring system (PMS) recording of cardiopulmonary parameters (level III of ASDA) has been validated in subjects with high probability of Obstructive Sleep Apnea (OSA) without comorbidities.
- Trial name
- NCT01455077
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Risk Reduction Behavior
Self-Affirmation: Construct Validity
Background: People respond differently when asked about their values. They also respond differently when they learn about how their actions affect their lives and health. Researchers want to learn more about these differences.
- Trial name
- NCT02317367
- Where
- United States
- Volunteers
- 3,112 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
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