Clinical trials: VALİDİTY
Esophageal and/or Cardia Cancer, Esophagectomy
Paracetamol Absorption Technique as a Method for Measuring Gastric Tube Outlet
Retention of the gastric tube after esophagectomy is a clinically important problem, and there is a need of a simple method to evaluate emptying rate from the gastric tube after esophagectomy.
- Conditions
- Esophageal and/or Cardia Cancer, Esophagectomy, Gastric Pull-up Reconstruction
- Trial name
- NCT02158286
- Testing
- Measuring emptying rate from the gastric tube
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Rheumatologic Disease, Pediatric ALL
Turkish Cultural Adaptation, Validity and Reliability of the "Gait Outcomes Assessment List"
The ultimate goal of treating children with lower extremity differences is to improve quality of life, optimize function, and maximize participation by addressing the physical, social, and psychological effects of lower extremity…
- Conditions
- Rheumatologic Disease, Pediatric ALL, Children, Only, Lower Extremity Problem
- Trial name
- NCT05846672
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University - Cerrahpasa
E-learning, Knowledge
Development and Validation of an E-learning Module on Systemic Anticancer Therapy and Its Effectiveness on the Knowledge Attitude and Practice of Nurses in Administering Systemic Anticancer Agents at a Specialized Cancer Centres in Oman.
Cancer is becoming more common worldwide. In countries like the United States, cases of breast and colorectal cancer have increased in recent years.
- Conditions
- E-learning, Knowledge, Attitude, Practice
- Trial name
- SACT -KAP (NCT07600853)
- Testing
- E-Learning, No E-Learning
- Where
- Oman
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos Comprehensive Cancer Center
Malignant Neoplasms
Validation of the Italian Version of the PRO-CTCAE
The aim of this study is to complete the validation process by testing the remaining two psychometric properties (validity and responsiveness) of the Italian version of the PRO-CTCAE in a large group of patients.
- Trial name
- NCT04416672
- Testing
- PRO-CTCAE items
- Where
- 25 sites in Italy
- Volunteers
- 3,675 people
- Sponsor
- National Cancer Institute, Naples
Periodontal Diseases, Periodontitis
Development, Validation, and Assessment of the Diagnostic Accuracy of a Questionnaire for Periodontitis Screening
The present study aims at validating the Italian version of one of the most widely used epidemiological questionnaires for periodontitis screening: the CDC/AAP questionnaire [hereafter referred to as the CDC/AAP_ITA…
- Trial name
- Q_ITA (NCT07461753)
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Azienda Unità Sanitaria Locale (A.U.S.L.) Ferrara, Italy
Abdominal Aortic Aneurysms
Validation of Fenestrations Positioning by Numerical Simulation
Fenestrated endovascular repair (FEVAR) is nowadays a recognized option to treat juxtarenal, pararenal or suprarenal abdominal aortic aneurysms in patients at high risk for conventional repair.
- Trial name
- FenSim (NCT03469245)
- Testing
- numerical simulation
- Where
- 9 sites in Austria, France and 3 more
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Peripheral Vein, Arterial Wave Reflections
Deep Learning Model for Predicting a Peripheral Venous Waveform-based Pulse Pressure Variation
Pulse pressure variation is a monitoring index that indicates the response to fluid therapy in patients receiving mechanical ventilation, and is used as a reference for patients with unstable hemodynamic conditions.
- Conditions
- Peripheral Vein, Arterial Wave Reflections, Pulse Pressure Variation, Stroke Volume Variation
- Trial name
- NCT06734650
- Testing
- peripheral waveform collection
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Coronary Artery Disease
Comparison of Digital Electronic Stethoscope to Computed Tomography (CT) Angiography in Detection of Coronary Artery Disease
The study is designed to evaluate the predictive diagnostic accuracy of SonoMedica's CardioSond digital electronic stethoscope in the detection of coronary artery disease (CAD) in patients without known disease who are referred…
- Trial name
- NCT01040923
- Testing
- CardioSond Cardiac Sonospectrographic Analyzer
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- SonoMedica, Inc.
Stroke
Validity of a New Stroke Dysphagia Screening Tool
Dysphagia or swallowing difficulty is common after stroke occurring in 25-78% of stroke survivors depending on the anatomic location of the stroke and the diagnostic test used.
- Trial name
- NCT01529723
- Where
- United States
- Sponsor
- Rhode Island Hospital
Neck Pain
Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization
Recently a clinical prediction rule (CPR) has been developed that identifies patients with neck pain who are likely to respond rapidly and dramatically to thoracic spine thrust manipulation and an active range of motion exercise.
- Trial name
- NCT00504686
- Testing
- manual therapy, exercise
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Franklin Pierce University
Multiple Sclerosis
Validation of a Laboratory Test Measuring Natalizumab (Tysabri®) Serum Levels in MS
Validating a peptide-based laboratory test enabling the measurement of Tysabri® serum levels (pharmacokinetics, PK) in multiple sclerosis patients undergoing therapy.
- Trial name
- IIT12 (NCT02965170)
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Rocky Mountain MS Research Group, LLC
Graft Rejection, Heart Transplantation
Diagnostic Validity of [18F]FSPG PET for the Assessment of Acute Rejection After Heart or Liver Transplantation
The a series of clinical studies of [18F]FSPG PET/CT showed that [18F]FSPG is safe and promising PET tracer for detecting inflammation with favorable biodistribution and pharmacokinetics in patients.
- Conditions
- Graft Rejection, Heart Transplantation, Liver Transplantation
- Trial name
- NCT04488094
- Testing
- [18F]FSPG
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Asan Medical Center
RheumatoId Arthritis
RABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFα BIologicals in Rheumatoid Arthritis
RABIOPRED is an in vitro non-invasive blood test, which aims to identify patients with rheumatoid arthritis (RA) who are not likely to respond to anti-TNFα and methotrexate combination therapy.
- Trial name
- RABIOPRED (NCT03016260)
- Testing
- Infliximab, Adalimumab, Etanercept
- Where
- 8 sites in Czechia, France and 3 more
- Volunteers
- 250 people
- Sponsor
- TcLand Expression S.A.
Pulmonary Embolism
Prospective Validation of an Acute Pulmonary Embolism Severity and Prognosis Prediction Model
The purpose of this study is to prospectively validate the first PUMCH model for acute PE severity and prognosis prediction based on multi-center data constructed in the pre-project period based on national population data, and…
- Trial name
- NCT05723003
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Peking Union Medical College Hospital
Bone Metastasis
Bone Pain Score Validation Initiative
Translation and validation of the BOMET-QoL-10 questionnaire in Germany and assessment of its validity and responsiveness.
- Trial name
- ARIE (NCT02293642)
- Where
- Germany
- Volunteers
- 370 people
- Sponsor
- iOMEDICO AG
Knee Pain
Validity and Reliability of Video-Based Functional Physiotherapy Assessment of Subacute Knee Injuries
This study aims to validate a function-based physiotherapy assessment for subacute knee pain without using specific knee tests. Assessments are conducted either in-person or via video consultations in primary care.
- Trial name
- NCT07212920
- Testing
- Physiotherapy digital assessment, Physiotherapy assessment - only functional tests
- Where
- 3 sites in Sweden
- Volunteers
- 138 people
- Sponsor
- Vastra Gotaland Region
Eating Disorders
Online Prevention Program for Eating Disorders Applied to College Students. Spanish Validation of the eBodyProject
The goal of this clinical trial is to analyze and compare in female college women two prevention programs for eating disorders, the Spanish Version of the eBodyProject and a traditional/educational prevention program.
- Trial name
- NCT05977582
- Testing
- Spanish version eBodyProject, Psychoeducationa Prevention Program
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Delirium, Dementia
Validating Studies to Assess the Diagnostic Accuracy of a Software Application for Detection and Monitoring of Attentional Deficits in Delirium
The study has two phases: Phase B and Phase C. The purpose of the Phase B study is to determine the performance (sensitivity and specificity) of a smartphone application (DelApp) to identify delirium in the whole inpatient…
- Trial name
- NCT02590796
- Testing
- No intervention given to participants
- Where
- 2 sites in United Kingdom
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Drug Interactions, Anesthesia, Conduction
Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery
Recently a new model for the interaction of sevoflurane propofol and remifentanil was developed. The potency of any combination of the three drugs is defined as probability that a subject tolerates laryngoscopy without movement…
- Trial name
- SPRV (NCT02457442)
- Testing
- Propofol and Remifentanil, Sevoflurane and Remifentanil, SPR 1
- Where
- Switzerland
- Volunteers
- 172 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome
Validity of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome
To evaluate the validity of lung ultrasound compared to CT chest and chest radiograph for diagnosis of ARDS and prediction of successful weaning from mechanical ventilation in those patients compared to traditional methods.
- Trial name
- NCT05886556
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Zagazig University
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