Clinical trials: VALİDİTY
Healthy
Nonin 4 Wavelength Cerebral Oximeter Study
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- Nonin4 (NCT01762722)
- Testing
- Reduction of inspired oxygen
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duke University
Obstructive Sleep Apnea
Validation of Sleep Apnea Screening Device
Obstructive sleep apnea (OSA) is the most common type of sleep apnea. OSA affects an estimated 18-40 million adults and 0.7-3% of all children in the US.
- Trial name
- NCT02814227
- Testing
- Zansors® sleep screening device
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Michigan
Surgery
Calibration and Validation of Masimo's O3 Regional Oximetry Device in Neonates, Infants and Children
The study will collect cerebral oximetry data from pediatric and neonatal subjects using the Masimo O3 regional oximetry device, for the purposes of device calibration and validation.
- Trial name
- NCT03123354
- Testing
- O3 regional oximeter sensor
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Masimo Corporation
Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
FLOW EVAL-AF: FLOW Mapping Electrogram VALidation in Patients With Persistent Atrial Fibrillation
FLOW EVAL-AF is a prospective, observational, single center pilot trial. The FLOW EVAL-AF trial is designed to identify driver sources in patients with persistent or longstanding persistent AF using EGF mapping and describe the…
- Conditions
- Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation, Atrial Fibrillation, Persistent, Arrhythmias, Cardiac
- Trial name
- FLOW EVAL-AF (NCT06260670)
- Testing
- Electrographic Flow™ Mapping using Ablamap® Software and FIRMap™ Catheter
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Ablacon, Inc.
Human Immunodeficiency Virus (HIV)
Alcohol Monitor Validation
This study will validate a wrist-worn alcohol monitor (BACtrack Skyn) in both laboratory and real-life settings.
- Trial name
- NCT03617705
- Testing
- Skyn Monitor Lab Session 1, Skyn Monitor Field Test with EMA App, Skyn Monitor Lab Session 2
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Florida
Mild Cognitive Impairment, Dementia
Validity of the Electronic Self-Administered Gerocognitive Examination (eSAGE)
The Self-Administered Gerocognitive Examination (SAGE) is a valid and reliable cognitive assessment tool used to identify both Mild Cognitive Impairment (MCI) and early dementia.
- Trial name
- eSAGE (NCT02544074)
- Testing
- neuropsychological testing, eSAGE testing
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy
SpO2 Validation of Noninvasive Red Diamond Disposable Pulse Oximeter Sensor
In this study, the level of oxygen within the blood will be reduced in a controlled manner by reducing the concentration of oxygen the study volunteer breathes.
- Trial name
- NCT03124602
- Testing
- Red Diamond Disposable Pulse Oximeter Sensor
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Atrial Fibrillation
ECG App Algorithms Clinical Validation Study
The purpose of the study is to evaluate the performance of ECG classification algorithms and their ability to classify heart rhythms into multiple categories of rhythms and heart rates
- Trial name
- NCT04247581
- Testing
- 1-lead ECG
- Where
- 4 sites in United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Chronic Patients, Heart Failure
Multicenter Trial for the Validation of Vitalera Platform
Vitalera has implemented a cloud platform for the telemonitoring of chronic patients through portable medical devices and an alarm-based system that issues health alerts when a patient's biomedical measurement is outside a…
- Trial name
- VAL-HIC (NCT05825755)
- Testing
- vitalera telemonitoring platform
- Where
- 10 sites in Spain
- Volunteers
- 97 people
- Sponsor
- humanITcare
Subjects Presenting With Normal Eyes
TopQ Cut-off Score Validation Study for 3D OCT-1 Maestro
The objective of this study is to validate the TopQ cutoff scores, which have been previously determined.
- Trial name
- NCT02447133
- Testing
- 3D OCT-1 Maestro
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Vascular Diseases
X-ray Dose Reduction Study for Cardiac Angiography and Intervention
ClarityIQ is a novel X-ray imaging technology, that combines advanced real-time image noise reduction algorithms, with state-of-the-art hardware to reduce patient entrance dose significantly.
- Trial name
- NCT01684826
- Testing
- Angiographic run with new algorithm and low dose (50% dose), Angiographic run with predecessor algorithm and dose (100%)
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Dental Caries
Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection
The aim of this study is to validate a near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany) for interproximal enamel caries detection and compare it with the established diagnostic methods (visual…
- Trial name
- NCT02657538
- Testing
- Non invasive caries treatment, Invasive caries treatment, Near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy
Validation of a Digital Twin Performing Strength Training
Background: Muscular strength training interventions have long been a cornerstone in the prevention, non-surgical management and rehabilitation of the entire spectrum of musculoskeletal injuries and diseases.
- Trial name
- NCT04849923
- Testing
- Strength training session
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Silvio Lorenzetti
Autism
Validation of Indiana's Early Evaluation Hub System
The investigators' objective is to test an innovative method of autism diagnosis that integrates clinical evaluation and assessment of biobehavioral markers in a large high-risk community-referral sample of children in the…
- Trial name
- EAER21 (NCT06586788)
- Testing
- Eyelink Portable Duo, Integrated PCP Diagnosis and Eye-tracking Biomarker
- Where
- 7 sites in United States
- Volunteers
- 154 people
- Sponsor
- Indiana University
Colorectal Cancer, High Cholesterol
Online Trial Examining Validity of the Shared Decision Making Process Survey With Video Vignettes
This study will recruit subjects online and randomly assigned them to one of four arms. The arms vary by clinical decision (colorectal cancer screening or treatment of high cholesterol) by video order (poor shared decision making…
- Trial name
- NCT04317274
- Testing
- Good high cholesterol video, Poor high cholesterol video, Good colon cancer screening video
- Where
- United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Presbyopia
Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses
This is a study to evaluate the clinical performance and subjective acceptance of an investigational contact lens (test), compared to a marketed lens (control) in an in-office setting.
- Trial name
- NCT03417557
- Testing
- Comfilcon A lens (test), Omafilcon B lens (control)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CooperVision, Inc.
Opioid Use Disorder
Assessment of Methadone and Buprenorphine in Interstitial Fluid
The purpose of this research is to determine if common medications for opioid use disorder (i.e., buprenorphine/naloxone, buprenorphine, methadone) and their metabolites (norbuprenorphine [a metabolite of buprenorphine]…
- Trial name
- NCT05546229
- Testing
- Microneedle based interstitial fluid collection
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cari Health Inc.
Epilepsy, Non-Epileptic Seizure
Validation of Criteria for Identification of Epileptiform Discharges in EEG Recordings of Patients With Epilepsy
Electroencephalography (EEG) records electric activity of the brain using electrodes placed on the scalp. EEG is an important tool in the diagnostic work-up of patients with epilepsy.
- Trial name
- CIED (NCT03533374)
- Testing
- Electroencephalogram (EEG) and visual evaluation
- Volunteers
- 100 people
- Sponsor
- Sándor Beniczky
Neonatal Brachial Plexus Palsy
Validation Study Of A Digital Measuring Device For Central Hand Representation In Children With A Neonatal Brachial Plexus Palsy
Hand function is one of the most complex and sophisticated sensorimotor skills, controlled by the interplay of precise motor efferent and multisensory afferent stimuli.
- Trial name
- NCT06950879
- Testing
- Measurement
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- University Hospital, Ghent
Healthy
Desaturation Validation of INVSENSOR00009
This study is designed to measure the trending accuracy of a noninvasive measurement of cerebral oxygen saturation. One Large sensor (adult sensor) and one INVSENSOR00009 will be placed on the subject's forehead.
- Trial name
- NCT03396835
- Testing
- INVSENSOR00009
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation