Clinical trials: VALİDİTY
Breast Cancer, Breast Neoplasms
Device Validation of Augmented-Reality ICG Fluorescence Imaging for Sentinel Lymph Node Detection in Breast Cancer
This study evaluates how accurately augmented-reality goggles with indocyanine green (ICG) near-infrared fluorescence can identify sentinel (first-draining) lymph nodes during breast cancer surgery.
- Conditions
- Breast Cancer, Breast Neoplasms, Sentinel Lymph Node, Lymphatic Metastasis
- Trial name
- NCT07683572
- Testing
- AR-ICG near-infrared fluorescence imaging
- Where
- North Macedonia
- Volunteers
- 200 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Inflammatory Bowel Disease, Perianal Fistula
Perianal Fistula (PAF) Validation and Burden of Illness Study
The purpose of this study is to gain a better understanding of the disease burden and unmet need of perianal fistulas within Crohn's disease (CD) in Ontario.
- Conditions
- Inflammatory Bowel Disease, Perianal Fistula, Crohns Disease
- Trial name
- NCT03981939
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 3,032 people
- Sponsor
- Takeda
Allergic Rhinitis, Rhinoconjunctivitis
Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
To assess the reproducibility of the allergic response in the cat allergic subjects, measured as the change from baseline of the Total Nasal Symptom Score (TNSS) on the two challenge days.
- Conditions
- Allergic Rhinitis, Rhinoconjunctivitis, Exposure
- Trial name
- NEC (NCT03414801)
- Testing
- Allergen Exposure
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Red Maple Trials Inc.
Stroke, Acute Ischemic Stroke
Validation of Velocity Curvature Index as a Diagnostic Biomarker Tool for Assessment of Large Vessel Stroke
This study is a multi-center, multi-phase, multi-cohort, prospective, randomized, open, blinded endpoint (PROBE), non-significant risk (NSR) device study including up to 420 evaluable subjects measured with the study device(s)…
- Trial name
- VOICE (NCT05547412)
- Testing
- NovaGuide 2 Intelligent Ultrasound System
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- NeuraSignal Inc dba NovaSignal
Depressive Disorder
Validity of the 3-item Patient Health Questionnaire (PHQ-3) for Identifying Moderate-to-Severe Depressive Symptoms Among Elderly Perioperative Patients: A Secondary Analysis of a National Prospective Cohort
This is a retrospective observational study based on our hospital's prospective peri-operative elderly patient database. We aim to evaluate the correlation between the 9-item Patient Health Questionnaire (PHQ-9) and the brief…
- Trial name
- NCT07818057
- Testing
- Retrospective data analysis
- Where
- China
- Volunteers
- 10,536 people
- Sponsor
- Chinese PLA General Hospital
Cancer
Entia Liberty: Accuracy and Precision
This study forms part of Entia's clinical evidence for regulatory submission. This study evaluates Entia Liberty's performance claims with venous blood compared to the gold standard clinical laboratory haematology analysers.
- Trial name
- NCT05025124
- Testing
- Entia Liberty
- Where
- United Kingdom
- Volunteers
- 530 people
- Sponsor
- Entia Ltd
Postoperative Recovery, Quality of Recovery From Anaesthesia
Validation of the Greek Postoperative Quality of Recovery Score 15
The goal of this observational study is to translate a patient questionnaire about recovery after an operation into Greek and assess how accurate, reliable, acceptable, and feasible this Greek version is.
- Conditions
- Postoperative Recovery, Quality of Recovery From Anaesthesia, PROMs, Validation Study
- Trial name
- (QoR-15Gr) (NCT06699823)
- Testing
- Greek version of QoR-15
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- IASO Thessalias
COPD
A Novel Incremental Step Test as an Alternative for the Assessment of Exercise Capacity in Patients With COPD
According to the official guidelines of pulmonary rehabilitation, a structured home-based approach is recommended to answer to the inadequate number of pulmonary rehabilitation services due to the chronic obstructive pulmonary…
- Trial name
- NCT04715659
- Testing
- Performance of step test (number of steps) for the assessment of exercise capacity
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Polytechnic Institute of Porto
SARS-CoV-2 Infection, Influenza A
Usability and Clinical Validation of the Flu A/B/COVID-19 + RSV Multiplex Rapid Test
This will be a prospective study for the clinical validation of the CorDx Tyfast Flu A/B/COVID-19 + RSV Multiplex Rapid Test for the qualitative detection and differentiation of SARS-CoV-2, Influenza A, Influenza B and RSV in AN…
- Conditions
- SARS-CoV-2 Infection, Influenza A, Influenza B, RSV
- Trial name
- CorDx 4in1 (NCT07875270)
- Testing
- Flu A/B/COVID-19 + RSV Multiplex Rapid Test
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- CorDx, Inc.
Hemorrhoidectomy, Hemorrhoid
Definition and Validation of HeQAS for the Assessment of Technical Quality in Excisional Hemorrhoidectomy
This observational multicenter study aims to develop and validate the Hemorrhoidectomy Quality Assessment Scale (HeQAS), a histopathological tool designed to assess the technical quality of excisional hemorrhoidectomy.
- Trial name
- NCT07719881
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Son Llatzer
Heart Failure, Heart Failure With Reduced Ejection Fraction
Consistently Assess Signs and Symptom of Heart Failure
Heart failure (HF) is a major public health problem. The New York Heart Association (NYHA) Functional Classification by a HF provider helps to guide their decisions in patient treatment.
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
- Trial name
- CLASS-HF (NCT05833581)
- Testing
- New York Heart Association Classification Guide
- Where
- 3 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Board of Trustees of Illinois State University
Adhesions Pelvic, Adhesion; Uterus
Prediction of Vesicouterine Adhesions by Transvaginal Sonographic Sliding Sign Technique: a Validation Study
The aim of this study is to evaluate the predictive value of the real-time dynamic TVS sliding sign for vesicouterine pouch adhesions in women and to test the inter- and intraobserver agreement of this new technique.
- Conditions
- Adhesions Pelvic, Adhesion; Uterus, Adhesion; Bladder
- Trial name
- NCT05862155
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Cataract, Catquest-9SF
Validation of the Catquest-9SF Questionnaire in Greek Language
Primary objective of this study is the validation of the Catquest-9SF questionnaire in the Greek population.
- Trial name
- NCT05323526
- Testing
- Catquest-9SF questionnaire, Demographics and clinical parameters
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Democritus University of Thrace
Constipation, Parkinson Disease
Validation of a Novel Functional Food Designed to Meet the Nutritional Needs of People Living With Parkinson's Disease
Constipation is a common complication and non-motor symptom of Parkinson's disease (PD) and affects up to 80% of people with PD.
- Trial name
- Food4PD (NCT06697626)
- Testing
- Inulin, B-vitamins and vitamin D
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- University of Ulster
Bipolar Disorder, Alcoholism
Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder
The purpose of this study is determine whether the use of topiramate is effective in the treatment of alcohol dependence (i.e. decreases drinking) in patients with bipolar disorder.
- Conditions
- Bipolar Disorder, Alcoholism, Alcohol Dependence
- Trial name
- NCT00572117
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Cerebral Palsy, Diplegic Cerebral Palsy
Validity and Reliability of the Modified Four Square Step Test (mFSST)
Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder that causes activity limitation resulting from movement and posture deficiencies as a result of a lesion in the immature brain.
- Conditions
- Cerebral Palsy, Diplegic Cerebral Palsy, Hemiplegic Cerebral Palsy, Gait Disorders, Neurologic
- Trial name
- cp (NCT05229523)
- Testing
- repeated assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Stroke, Muscle Tone Abnormalities
Stroke and Assessment of Muscle Tone
Spasticity is defined as a state of increased muscle tone, which evokes an increased resistance to a passive and fast stretching of the muscle.
- Conditions
- Stroke, Muscle Tone Abnormalities, Pain, Muscle Spasticity
- Trial name
- NCT03814460
- Testing
- Assessment of Tone, Pain and Thickness
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Seville
Healthy Aging, Risk Reduction
Validation of the REMINDER Dementia Risk Reduction Program
Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies.
- Conditions
- Healthy Aging, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT05296980)
- Testing
- REMINDER, Brain health Psychoeducation
- Where
- Portugal
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Insomnia Disorder
Evaluating the Validity and Acceptability of a Fully-automated Interview to Diagnose Insomnia Disorder: a Pilot Study
Objective: to evaluate if a fully-automated diagnostic interview for insomnia disorder is suitable for clinical and research purposes (adequate sensitivity and specificity) and is acceptable to patients. Study main outcomes: 1.
- Trial name
- NCT05805527
- Testing
- mobile health application named KANOPEE
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University of Bordeaux
Pancreatic Cancer
EpiDetect Study: Clinical Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Patients
Bluestar Genomics has developed a non-invasive test that aids in the qualitative detection of occult pancreatic cancer in patients with new onset type II diabetes (NOD) who are 50 years old or older.
- Trial name
- NCT05188573
- Testing
- Early detection pancreatic cancer test, Early detection pancreatic cancer test and MRI Imaging
- Where
- United States
- Sponsor
- ClearNote Health
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