Clinical trials: VATS
Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis)
Intraoperative Paravertebral Block and Postoperative Complications
This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis), Pulmonary Infections, Respiratory Failure Without Hypercapnia
- Trial name
- IPVB and POCs (NCT07211529)
- Testing
- Paravertebral Block (PVB)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV)
Individualized Open Lung Ventilation and Postoperative Pulmonary Complications in Thoracic Surgery
This prospective, single-center, randomized controlled trial aims to evaluate the efficacy of an intraoperative "Individualized Open Lung Ventilation" strategy compared to a standard lung-protective ventilation strategy in…
- Conditions
- Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV), Thoracic Surgery, Video Assisted
- Trial name
- NCT07387822
- Testing
- Standard Lung-Protective Ventilation, Individualized Open Lung Ventilation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Aerospace Center Hospital
Postoperative Cognitive Dysfunction, Acute Postoperative Pain
Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients
To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.
- Conditions
- Postoperative Cognitive Dysfunction, Acute Postoperative Pain, Chronic Postsurgical Pain
- Trial name
- NCT05364216
- Testing
- Measurement of cognitive function, Thoracic paravertebral block, The assessment of cognitive function
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Heart Diseases
Video-Assisted Left Atrial Appendage Exclusion Trial
Exclusion of the LAA(Left Atrial Appendage) using the TigerPaw II System with VATS technique is safe and effective.
- Trial name
- VALET (NCT02226133)
- Testing
- LAAx, Inc. TigerPaw® System II
- Where
- 4 sites in United States
- Sponsor
- LAAx, Inc.
Non Small Cell Lung Cancer
Assessment of Video Assisted Thoracoscopic Surgery (VATS) Versus Open Surgery for Patients Undergoing Lobectomy
Assessment of VATS versus standard open surgery for treatment of non small cell lung cancer.
- Trial name
- NCT00912366
- Testing
- Lobectomy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Medtronic - MITG
Primary Spontaneous Pneumothorax
Study Compares Pneumothorax Recurrence: Absorbable Mesh vs. Pleurectomy in Primary Spontaneous Pneumothorax.
This is a prospective, randomized controlled trial (pilot study) that aims to determine the incidence of post-operative recurrent pneumothorax within one-year timeframe after video-assisted thoracoscopic blebectomy/bullectomy…
- Trial name
- NCT06413966
- Testing
- Partially absorbable mesh, Apical pleurectomy
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Chiang Mai University
Thoracic Diseases
Ventilatory Influence on Cerebral Oxygenation During VATS
During (OLV) in (VATS) ; many physiological factors may increase risk of hypoxemia such as positioning and intrapulmonary shunt thus compromising cerebral blood flow and oxygenation, resulting in postoperative neurocognitive…
- Trial name
- NCT05033353
- Testing
- Monitoring of regional cerebral oxygenation
- Where
- Saudi Arabia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain, Postoperative
Flexibility of Cognition And Persistent Pain
This observational study aims to determine the association between preoperative cognitive flexibility and the risk of developing PPSP by preoperative administration of cognitive tests.
- Trial name
- FlexCAPP (NCT02579538)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Surgery, Thoracic
Comparing Erector Spinae Plane (ESP) and Thoracic Paravertebral (TPV) Block Analgesic Effect After Elective VATS
The aim of the study is to compare two different locoregional techniques in VATS.
- Trial name
- NCT05798585
- Testing
- ESP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Andrea Saporito
Malignant Pleural Effusion, Thoracic Cancer
Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
- Trial name
- NCT05872126
- Testing
- VATS-Surgical pleurodesis, Tube Drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain
Comparison of the Effects of Erector Spinae Area (ESP) Block and Thoracic Paravertebral Block (TPVB) on Acute Pain, Postoperative Persistent Pain and Neuropathic Pain in Video-Assisted Thoracoscopic Surgery
VATS is a minimally invasive approach that allows the introduction of a video camera and surgical instruments into the thoracic cavity through small incisions made in the chest wall.
- Trial name
- NCT06672848
- Testing
- Numeretic rating scale (NRS), Brief Pain Inventory (BPI), The S-LANSS Pain Score
- Volunteers
- 118 people
- Sponsor
- Aydin Adnan Menderes University
Lung Cancer
Regional Haemodynamic Changes in Radial Artery Assessment With Continuous Pulsed-wave Doppler Ultrasound
The objective of the trial was to evaluate velocity-associated parameters of pulsed-wave Doppler ultrasound at induction, discharge from the post-anaesthesia care unit and during inspiratory cough in addition to the consumption…
- Trial name
- NCT03302221
- Testing
- 0.5% ropivacaine paravertebral block, 0.25% ropivacaine epidural block, 0.5% ropivacaine local anaesthesia
- Where
- China
- Sponsor
- China Medical University, China
Pain, Postoperative
Prediction of Persistent Postsurgical Pain After Video-assisted Thoracic Surgery (VATS)
Prospective cohort study of factors predisposing to persistent post surgical pain after video-assisted thoracic surgery
- Trial name
- NCT01300195
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabete Mellitus, VATS
Total Intravenous and Balanced Anesthesia in Diabetic Patients Undergoing Video-Assisted Thoracoscopy
Video-assisted thoracoscopy is a minimally invasive surgical technique used to diagnose and treat problems in chest. Diabetics are more prone to infections, slower wound healing and other complications during and after surgery.
- Conditions
- Diabete Mellitus, VATS, TIVA
- Trial name
- NCT07496593
- Testing
- Propofol + fentanyl + Atracurium, Isoflurane and Atracurium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Lung Cancer
Ketamine In Thoracic Surgery (KITS) Trial
The primary aim of the study is to demonstrate a reduction in circulating interleukin 6 levels at 4 and 24 hours after completion of lobectomy (either VATS or open).
- Trial name
- KITS (NCT00504725)
- Testing
- Ketamine, 0.9% saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Nerve Block, Video-Assisted Thoracic Surgery
Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) provides an opportunity to penetrate the thoracic cavity by video through an incision into the chest wall and facilitate surgical operation of lung pathologies.Various regional methods…
- Trial name
- NCT03483415
- Testing
- Morphine Sulfate, Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Neuromuscular Blockade
Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery
The main objective of the study is to compare the frequency of intraoperative spontaneous diaphragmatic movements and breath-initiation efforts in participants undergoing robotic and/or thoracic surgery under deep neuromuscular…
- Trial name
- NCT07706504
- Testing
- TetraGraph (Senzime)-Guided Neuromuscular Monitoring (Dominant Hand), TwitchView (Blink)-Guided Neuromuscular Monitoring (Dominant Hand)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anesthesia, Surgery
The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery
This study evaluates the influence of individualized lung-protective ventilation strategy(LPVS) on postoperative pulmonary complications(PPCs) through a randomized controlled trial when children undergoing thoracoscopic surgery…
- Trial name
- PEEP (NCT05386901)
- Testing
- Conventional positive end-expiratory pressure(PEEP), Lung dynamic compliance guided positive end-expiratory pressure(PEEP)
- Where
- China
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Jiaxiang Chen
Video-assisted Thoracoscopic Surgery
Patient-Controlled Thoracic Paravertebral Block After Video-Assisted Thoracoscopic Surgery
Thoracic surgery is commonly associated with severe postoperative pain and marked impairment of respiratory function.1 Minimally invasive video-assisted thoracic surgery (VATS) is assumed to result in better quality of life and…
- Trial name
- NCT02237664
- Testing
- Continuous paravertebral analgesia (C-PVB), Patient-controlled paravertebral analgesia (PC-PVB)
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Lung Neoplasms
Pre-operative Localization of Ground Glass Solitary Pulmonary Nodules
Objectives: The main drawback of the hook-wire technique for locating ground glass nodules before video assisted thoracoscopic surgery (VATS) resection is the risk of the hook dislodging during single lung ventilation as the lung…
- Trial name
- SLIDINGWIRE (NCT06195657)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire de Nice