Clinical trials: VITILIGO
Vitiligo
Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo
A COMPARATIVE STUDY BETWEEN RECEPIENT SITE PREPARATION USING DERMABRASION, LIQUID NITROGEN INDUCED BLISTER AND DERMAROLLING SYSTEM IN AUTOLOGOUS NON CULTURED EPIDERMAL CELL SUSPENSION PROCEDURE IN STABLE VITILIGO PATIENTS
- Trial name
- NCT03668834
- Testing
- Dermabrasion with NCES, Dermaroller with NCES, Liquid nitrogen induced blister with NCES
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Vitiligo
The Value of Adding Mini-oral Pulse Steroid Therapy in Preventing Peri-lesional Halo Post Non-cultured Epidermal Cell Suspension (NCES) in Cases With Stable Segmental and Non-acral Vitiligo.
The goal of this clinical trial is to learn if adding mini-oral pulse steroid therapy improves the results of non-cultured epidermal cell suspension (NCES) surgery in patients with stable vitiligo.
- Trial name
- NCT07472816
- Testing
- Non-cultured epidermal cell suspension (NCES) surgery, Oral mini pulse, Excimer Sessions
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Vitiligo
Atorvastatin in Active Vitiligo
Condition: Non segmental and active vitiligo of adulthood. Main objective: To evaluate the efficacy of a daily treatment with atorvastatin 80mg/d combined to UVB compared to UVB alone in active vitiligo after 6 months of…
- Trial name
- NCT02432534
- Testing
- Atorvastatin, UVB
- Where
- 2 sites in France, Indonesia
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo
Virus Early Transcription Factor (VETF) Multicenter Phototherapy Protocol
Background Phototherapy UVB TL01 currently represents the first choice in treatment to induce the repigmentation of vitiligo spots.
- Trial name
- VETF (NCT00525395)
- Testing
- Sequential phototherapy, Continuous phototherapy
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituti Fisioterapici Ospitalieri
Vitiligo
Prostaglandin F2-alpha (PGF2α) in Vitiligo
study the cutaneous expression of PGF2α in vitiligo patients and compare it with normal control subjects.
- Trial name
- NCT03755830
- Testing
- Skin biopsy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stable Vitiligo
Induced Pluripotent Stem Cell Derived Exosomes Nasal Drops for the Treatment of Stable Vitiligo
Evaluate the efficacy of induced pluripotent stem cell-derived exosomes (iPSC-Exos) for the treatment of stable vitiligo
- Trial name
- NCT06810869
- Testing
- human induced pluripotent stem cell derived exosomes （GD-iExo-003）
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Second Affiliated Hospital of Wannan Medical College
Vitiligo
A Proof of Concept, Phase 1 Study of CGB-600 for the Topical Treatment of Non-Segmented Facial Vitiligo
The goal of this clinical trial is to learn if drug CGB-600 works to treat vitiligo on the face and neck in participants between 18-60 years of age. It will also learn about the safety of CGB-600.
- Trial name
- NCT07357870
- Testing
- Drug: CGB-600 gel, experimental drug
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- CAGE Bio Inc.
Vitiligo, Treatment
Efficacy of Intralesional Triamcinolone Injection in the Treatment of Vitiligo
A randomized split-body pilot study was planned to confirm efficacy of intralesiona triamcinolone injection in patients with vitiligo
- Conditions
- Vitiligo, Treatment, Intralesional Injection, Corticosteroid
- Trial name
- NCT03365141
- Testing
- Triamcinolone acetonide 0.4mg/cc, Phototherapy (NBUVB or excimer laser), Topical tacrolimus
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Vitiligo
Efficacy and Safety of Ruxolitinib Cream in Chinese Children Aged 2-11 Years With Non-segmental Vitiligo
The goal of this clinical trial is to evaluate the efficacy and safety of Ruxolitinib Phosphate Cream in treating non-segmental vitiligo in children aged 2 to 11 years under real-world conditions.
- Trial name
- NCT07595939
- Testing
- Ruxolitinib 1.5% Cream BID
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Vitiligo, Pigmentation
Randomized, Split-body, Single-blinded Clinical Trial of NB-UVB Treatment for Vitiligo
The objective of this study is to assess the effectiveness and safety of narrowband-ultraviolet B (NB-UVB) treatment in adult subjects with vitiligo.
- Conditions
- Vitiligo, Pigmentation, Dyschromia
- Trial name
- NCT02506101
- Testing
- narrow-band ultraviolet B phototherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Vitiligo
The Value of Methotrexate in NCES for Stable Vitiligo
The goal of this clinical trial is to learn if adding a six months course of Methotrexate would improve the results of non cultured epidermal suspension (NCES) in adult patients with acral and resistant vitiligo lesions over the…
- Trial name
- NCT07352293
- Testing
- Non cultured epidermal suspension
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Cairo University
Vitiligo
Use of Allogeneic Extracellular Secretomes (EV)Derived From Umbilical Cord Mesenchymal Stromal Cells: a Phase I Open-label Safety Trial.
Aim of the study: The primary endpoint of this work is to explore the safety of allogeneic extracellular secretomes "extracellular vesicles" (EV) derived from umbilical cord mesenchymal cells (HUCMSCs) when injected perilesional…
- Trial name
- EVVitiCTC (NCT06813027)
- Testing
- EV
- Where
- Jordan
- Volunteers
- 13 people
- Sponsor
- University of Jordan
Vitiligo - Macular Depigmentation
0.005% Latanoprost Gel for Nonsegmental Vitiligo
Latanoprost, a prostaglandin F2α (PGF2α) analog used for glaucoma treatment, is known to cause iris darkening, hypertrichosis, and periocular skin hyperpigmentation.
- Trial name
- NCT07016113
- Testing
- 0.005% latanoprost gel, 0.1% mometasone furoate cream
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Universitas Padjadjaran
Dermatologic Disease, Vitiligo
Vitiligo Registry for Adults and Children in the UK
Vitiligo is the most common depigmentation disorder affecting around 1% of the population worldwide. Fifty two percent of patients develop vitiligo before the age of 20 and around 80% develop vitiligo before the age of 30 years…
- Trial name
- VIRTUAL-UK (NCT06218082)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Vitiligo Vulgaris, Psoriasis
PALLAS Laser for Skin Diseases
The primary objective of this study is to get clinical experiences with the PALLAS laser in the treatment of skin conditions that respond well to UV light (vitiligo, psoriasis, alopecia areata, atopic dermatitis).
- Conditions
- Vitiligo Vulgaris, Psoriasis, Alopecia Areata, Atopic Dermatitis
- Trial name
- PALLAS-UV (NCT07250997)
- Testing
- UVB laser treatment
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Szeged University
Scars, Hypopigmented Scar
Treatment of Hypopigmented Scars With Bimatoprost
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR).
- Conditions
- Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar
- Trial name
- NCT06122090
- Testing
- Bimatoprost, Saline
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Vitiligo
Hair Transplantation for Treatment of Vitiligo
There are several surgical methods to treat vitiligo patches, and follicular unit extraction (FUE) is one among them. FUE, performed using punch biopsy extraction and hair follicle transplantation, has proven safe and effective…
- Trial name
- NCT04858152
- Testing
- Follicular Unit Extraction via punch biopsy
- Where
- United States
- Sponsor
- Mehdi Rashighi
Totest Sensory Symptoms in Active Vitiligo
Sensory Symptoms in Active Vitiligo
This work aims to assess sensory symptoms in early active vitiligo patients (segmental, non-segmental, or mixed) and to measure 3 neuropeptides expression in their lesional skin [neuropeptide Y(NPY), calcitonin gene-related…
- Trial name
- NCT05390164
- Testing
- skin biopsy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo
Effect of Combination Non Steroidal Antiinflammatory Drugs and Narrowband UVB Treatment in Non-Photoadapters
Narrow band UVB phototherapy is the mainstay of therapy for vitiligo. However, about 1/3 of patients cannot respond to phototherapy.
- Trial name
- NCT05256147
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System