Clinical trials: VOLUME OF FLUID
Liver Transplantation (LT), End-stage Liver Disease (ESLD)
Restrictive Fluid Management In Liver Transplantation (REFIL)
The goal of the REFIL-2 study is to evaluate the effectiveness of a low splanchnic blood volume restrictive fluid management strategy (a strategy that involves limiting fluid administration and prioritizing the use of medications…
- Trial name
- REFIL-2 (NCT07695363)
- Testing
- Low splanchnic blood volume restrictive fluid management strategy, Phlebotomy, Optimized cardiac output liberal fluid management strategy
- Where
- 4 sites in Canada
- Volunteers
- 866 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Stroke Volume Variation, SVV-FloTrac
A Comparison of Thoracic Electrical Bioimpedance and FloTrac/Vigileo
Stroke volume variation (SVV) is an indicator used to assess the patient's volume status. The FloTrac system (Edwards Lifesciences, Irvine, CA) continuously monitors cardiac output (CO) and SVV (SVV-FloTrac) by analyzing the…
- Conditions
- Stroke Volume Variation, SVV-FloTrac, Thoracic Electrical Bioimpedance, Fluid Responsiveness
- Trial name
- NCT06143111
- Testing
- Flotrac Group, BioZ Group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Obstructive Sleep Apnea
The Impact of Fluid Volume Shifts on Upper Airway Collapse and Obstructive Sleep Apnea in Surgical Patients
The objective of this study is to examine the contribution of intravenous (IV) fluid administration and rostral fluid shift from the legs to the neck thereby leading to worsening of sleep apnea following surgery.
- Trial name
- NCT03850041
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Brain Tumor
Effect of Goal-directed Fluid Therapy Based on Stroke Volume Variation on Metabolic Acidosis in Patients Undergoing Brain Tumor Surgery
In patients undergoing craniotomy, 0.9% normal saline is commonly administered in order to reduce cerebral edema. Excessive administration of 0.9% normal saline has been to reported to cause hyperchloremic metabolic acidosis.
- Trial name
- NCT01738880
- Testing
- SVV, CVP
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Kidney Transplantation
Stroke Volume Variation and Pulse Pressure Variation as Predictors of Fluid Responsiveness During Kidney Transplantation
The aim pf this prospective study is to investigate the ability of stroke volume variation (SVV) and pulse pressure variation (PPV) to predict fluid responsiveness in patients undergoing kidney transplantation.
- Trial name
- NCT02459470
- Testing
- Fluid loading
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Samsung Medical Center
Gastric Residual Volume
Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries
General Anesthesia requires preoperative fasting according to specific instructions. Regarding Fasting Guidelines, The American Society of Anesthesiologists (ASA) recommends patients to fast from fatty food or meat eight hours…
- Trial name
- NCT05570292
- Testing
- Domperidone, Folic acid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Nephrolithiasis, Low Urine Volume
Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis
The primary objective of this study would be to determine whether utilization of this technology improves adherence to recommended increases in hydration for stone forming patients with low urine volume relative to standard…
- Trial name
- HidrateMe (NCT02938884)
- Testing
- HidrateSpark Water Bottle
- Where
- 4 sites in United States
- Volunteers
- 85 people
- Sponsor
- University of Minnesota
Major Abdominal Surgery, Duodenohemipancreatectomy
Intraoperative Haemodynamic Optimization Comparing Flow and Pressure Parameters
The purpose of the study is to confirm the hypothesis that flow treatment algorithm based on cardiac index trending by transesophageal Dopplerometry would result in reduced complications and reduced length of hospital stay in…
- Conditions
- Major Abdominal Surgery, Duodenohemipancreatectomy, Rectal Resection, Extensive Bowel Surgery
- Trial name
- Flow-press (NCT02104687)
- Testing
- Flow group, Press group
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Ostrava
Circulatory Failure
Small Volume Fluid Challenge as a Predictor of Fluid Responsiveness in Patients With Circulatory Failure
Assessment of intravascular volume status is difficult in critically ill patients. Evidence suggests that only 50% of hemodynamically unstable patients respond to a fluid challenge.
- Trial name
- NCT03622099
- Testing
- Normal Saline Flush, 0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Menoufia University
Respiratory Failure, Acute Respiratory Failure Requiring Reintubation
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Reintubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02105298
- Where
- United States
- Volunteers
- 104,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Fluid and Electrolyte Imbalance
Volume Kinetics of Fluid Resuscitation in Early Sepsis
The recommended volume resuscitation for patients with early sepsis-induced hypoperfusion is at least 30 ml/kg of crystalloid administered within the first three hours.
- Trial name
- NCT06499701
- Testing
- Ringer's Lactate
- Where
- 2 sites in Romania
- Volunteers
- 13 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Satiety, Appetite
Effect of Liquid Volume and the Amount of Incorporated Gas Into a Carbohydrate/Protein Beverage on Satiety
Liquid foams can be formed by trapping pockets of gas in a beverage. The primary objective of this study is to test the individual contribution, and possible interaction, of the liquid volume and gas to liquid volume ratio (i.e.
- Trial name
- NCT02405494
- Testing
- Beverage 1, Beverage 2, Beverage 3
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Development of Non-invasive Protocol
Fluid Volume During Fluid Shifts
This study is designed to answer the question of if several non-invasive methods are comparable to the invasive clinical gold standard of radiolabeled albumin in terms of detecting changes in fluid volume.
- Trial name
- NCT03447574
- Testing
- ethanol dilution
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Blood Volume Expansion
Ability of Changes in End Tidal Carbon Dioxide to Assess the Stroke Volume Effects of a Volume Expansion of 250ml of Crystalloid in the Operating Room
Volume expansion is the cornerstone of perioperative hemodynamic optimization. The main objective of volume expansion is to increase and to maximize stroke volume.
- Trial name
- REVCO2 (NCT03635307)
- Testing
- End Tidal Carbon Dioxide measure
- Where
- France
- Volunteers
- 115 people
- Sponsor
- University Hospital, Bordeaux
Pancreaticoduodenectomy, Stroke Volume Variation
Goal-directed Fluid Therapy on Complications After Pancreaticoduodenectomy
Optimal fluid balance is critical to minimize anastomotic edema in patients undergoing pancreaticoduodenectomy. This study examined the effects of decreased fluid administration on rates of postoperative pancreatic leak and…
- Trial name
- NCT03699917
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Wake Forest University Health Sciences
Lipodystrophy
Intraoperative Fluid Management of Liposuction , Cardiometry Versus Rohrich Formula
The aim of the study is to compare the hemodynamic parameters of fluid resuscitation using Rohrich formula to cardiometry guided stroke volume variation in patients undergoing large volume liposuction surgery .
- Trial name
- NCT05402982
- Testing
- Electrical Cardiometry (EC) ICON, Rohrich formula
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahmed Abdel Wahed Ali
Congestive Heart Failure
Correlation of Intrathoracic Impedance Measures With Blood Plasma Volume in Congestive Heart Failure
Congestive heart failure is a condition in which the heart is weakened and is unable to pump enough blood to the organs of the body to meet the demands of the body.
- Trial name
- Optivol (NCT00603213)
- Testing
- Blood Volume Analysis, Echocardiogram
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Hyponatremia, Hyponatremia With Extracellular Fluid Depletion
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status
Hyponatremia is the most frequent electrolyte disorder encountered in clinical practice. The patient approach, however, is still problematic, above all because hyponatremia is a manifestation correlated to various pathological…
- Conditions
- Hyponatremia, Hyponatremia With Extracellular Fluid Depletion, Hyponatremia With Normal Extracellular Fluid Volume, Hyponatremia With Excess Extracellular Fluid Volume
- Trial name
- NCT04402190
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Renal Failure, Chronic Kidney Diseases
Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients
The purpose of the current investigation is to provide proof of concept for a future approach to improve UF prediction accuracy.
- Trial name
- pPD (NCT06443021)
- Testing
- PD cycler
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Preoperative Fasting
Comparing the Gastric Emptying Times of Underweight and Healthy-weight School-aged Children
In the recent literature, preoperative fasting times for pediatric patients are limited to one hour for clear fluids. Studies related to gastric emptying times mostly searched for normal-weight children.
- Trial name
- NCT06522204
- Testing
- %5 Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karaman Training and Research Hospital