Clinical trials: VOLUME OF FLUID
Satiety, Appetite
Effect of Liquid Volume and the Amount of Incorporated Gas Into a Carbohydrate/Protein Beverage on Satiety
Liquid foams can be formed by trapping pockets of gas in a beverage. The primary objective of this study is to test the individual contribution, and possible interaction, of the liquid volume and gas to liquid volume ratio (i.e.
- Trial name
- NCT02405494
- Testing
- Beverage 1, Beverage 2, Beverage 3
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Cirrhosis, Liver, Volume Overload
Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients
A common complication of the progression of cirrhosis is fluid retention (ascites, edema, or pleural effusion). Loop diuretics are the treatment of choice for fluid retention in cirrhotic patients; however, many of these patients…
- Conditions
- Cirrhosis, Liver, Volume Overload, Fluid Overload
- Trial name
- NCT04216784
- Testing
- Furosemide Injection, Albumin Human
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Rush University Medical Center
Acute Circulatory Failure
Central Venous Pressure Change With Volume Challenge in Patients With Hemodynamic Instability
We conducted this study to assess the value of early change in central venous pressure (CVP) in predicting fluid responsiveness in mechanically ventilated patients.
- Trial name
- CVPCHI (NCT01630577)
- Testing
- volume expansion using modified gelatin
- Where
- 2 sites in Tunisia
- Volunteers
- 70 people
- Sponsor
- University of Monastir
Gastric Retention
GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound
This study will enroll patients 18 years and older who are taking a GLP-1/GIP medication and 1) are scheduled for elective surgery and meet ASA fasting guidelines (nothing by mouth for at least 8 hours prior), or 2) scheduled…
- Trial name
- NCT07251803
- Testing
- Gastric Ultrasound
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Cancer, Neurological Injury
Protein Top-up Acceptability Study for Patients With Increased Protein Needs
The aim of this prospective, single-arm intervention study is to evaluate the acceptability (compliance, gastrointestinal tolerance, and palatability) to a low calorie, low volume, ready to use, high protein liquid in patients…
- Conditions
- Cancer, Neurological Injury, Respiratory Disease, Stroke
- Trial name
- NCT04607330
- Testing
- High protein liquid
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Nutricia UK Ltd
Liver Transplantation, End-stage Liver Disease (ESLD)
Restrictive Fluid Management In Liver Transplantation (REFIL) - Pilot
Hypothesis: A Canadian multicentre clinical trial is feasible. Study Design: Multicenter internal pilot parallel arm randomized controlled trial.
- Trial name
- REFIL-1 (NCT05647733)
- Testing
- Low splanchnic blood volume restrictive fluid management strategy, Optimized cardiac output liberal fluid management strategy, Phlebotomy
- Where
- 4 sites in Canada
- Volunteers
- 138 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Fluid Management
Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection
Studies have demonstrated that the rate of change in stroke volume variation (SVV) can be used to determine the volume of body fluids during major abdominal surgery.
- Trial name
- NCT05361252
- Testing
- SVV-guided fluid management
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Chronic Kidney Diseases Stage 5
Dietary and Dialysate Sodium Reduction on Body Fluid Volume and Inflammatory State in Hemodialysis Patients
Objective: To evaluate the influence of dietary sodium reduction on body fluid volume and inflammatory state in hemodialysis (HD) patients. Design: Prospective controlled randomized study.
- Trial name
- NCT01458808
- Testing
- Dietary sodium restriction, Dialysate sodium concentration reduction
- Volunteers
- 59 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Respiratory Failure, Acute Respiratory Failure Requiring Reintubation
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Reintubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02105298
- Where
- United States
- Volunteers
- 104,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy
240 mL Water Drink Study
The GI MRI Research group at the University of Nottingham has been developing new, non-invasive magnetic resonance imaging (MRI) techniques to image the gastrointestinal tract.
- Trial name
- NCT01792453
- Testing
- Spring water
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Liver Cirrhosis
Dynamic Preload Parameters During Liver Transplantation
The arterial system compliance is compromised in liver cirrhotic patients. Dynamic preload variables are either pressure-based (e.g.pulse pressure variation; PPV), flow-based (e.g.
- Trial name
- NCT01971333
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Clinical CT Abdomen/Pelvic With Oral Contrast and Sedation
CT Residual Gastric Fluid Volume
Hypothesis: The investigators hypothesize that more than 50% of the patients receiving enteric contrast material (ECM) < 2 hours of anesthesia/sedation would have residual gastric fluid volume (GFV) > 0.4 ml/kg.
- Trial name
- NCT02239068
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Emphysema or COPD, Emphysema
The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema
The goal of this clinical trial is to learn if bronchoscopic lung volume reduction with endobronchial thermal liquid ablation (ETLA) works to treat severe emphysema in terms of feasibility and safety.
- Conditions
- Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD
- Trial name
- NCT06655428
- Testing
- Endobronchial Therman Liquid Ablation (ETLA)
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- Morair Medtech, LLC
Heart Failure
Necklace-Shaped Sensor for Non-Invasive Monitoring of Stroke Volume and Cardiac Output
Study will compare measurements made with Necklace device for stroke volume/cardiac output with values from a FDA-approved reference device. The gold standard that will be used is Cardiac MRI.
- Trial name
- NCT02719301
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Cirrhosis, Liver
Transitional Care Program for Fluid Overload in Cirrhosis
The goal of this clinical trial is to learn about an intensive monitoring plan (transitional care program) in patients with cirrhosis and excessive swelling that are going to be discharged from the hospital.
- Trial name
- NCT06174272
- Testing
- Transitional Care Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Obese Patients
Intragastric Balloon for Treatment of Overweight and Obesity: Which is the Best Filling Volume?
TITLE: Randomized study conducted in a single center, with the aim of comparing the three main filling volumes of the intragastric balloon in overweight or obese patients (BMI >27 and <60 kg/m2).
- Trial name
- NCT06673550
- Testing
- Intragastric balloon
- Where
- Italy
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Mater Olbia Hospital
Total Fluid Volume Decreased
Preoperative Ultrasound Guided Evaluation of SVC-CI and IVC -CI as Predictors of Hypotension After Induction of Anaesthesia in Major Onco-surgery
Patients undergoing major Oncosurgeries are fluid deficit due to preoperative fasting , inadequate intake due to disease hence prone to development of hypotension after induction of general anaesthesia owing to vasodilatory…
- Trial name
- SVC IVC CI (NCT05548920)
- Testing
- Ultrasound guided Superior Vena Cava Collapsibility Index, Inferior Vena Cava Collapsibility Index
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593717
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Anomaly; Venous Return
Volume-challenge in Morbid Obesity
Preoperative venous return stability and euvolemia is essential in management of morbidly obese patients. Fluid therapy regimes for patients with high BMI, especially with focus on preoperative management, are rare and not in…
- Trial name
- NCT01748513
- Testing
- preoperative venous return optimizing
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Umeå University
Fluid Balance
Effects of Beverage Volume, Glycerol Concentration, and Sodium Concentration on Fluid Balance in Healthy Euhydrated Men and Women at Rest
The presence of certain ingredients such as sodium and glycerol can facilitate retention of the fluid consumed via renal water reabsorption.
- Trial name
- NCT06854471
- Testing
- Electrolyte solution without glycerol beverage 1, Electrolyte solution without glycerol beverage 2, Electrolyte solution without glycerol beverage 3
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D