Clinical trials: VOLUME OF FLUID
Stroke Volume Variation
Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft
- Trial name
- NCT01404455
- Testing
- HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Severance Hospital
To Assess the Ability of PI to Detect Preload Responsiveness
Changes in Pulse-Oximetry Perfusion Index Induced by Tidal Volume Challenge Versus Fluid Volume Challenge to Detect Preload Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume
The primary goal of this study was to assess the ability of PI changes induced by a Vt challenge or fluid challenge test to detect preload responsiveness in critically ill adult patients on mechanical ventilation with low-tidal…
- Trial name
- NCT06673862
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Fluid Responsiveness, Prone Position
Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery
NICOM® is a recently developed noninvasive cardiac output monitoring device, and indices derived from NICOM® such as SVV has been reported to predict fluid responsiveness in the previous studies.
- Conditions
- Fluid Responsiveness, Prone Position, Non Invasive Cardiac Output Monitoring
- Trial name
- NCT02277353
- Testing
- Fluid loading to evaluate fluid responsiveness
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Hypotension
Norepinephrine and Phenylephrine, Which Better for Elderly?
this is a prospective, double-blinded and single-center study. this study is based on the Stroke volume variation fluid guided therapy, to compare the effects of norepinephrine and phenylephrine in treating perioperative…
- Trial name
- NCT04067817
- Testing
- norepinephrine, Phenylephrine
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University
Disorders Associated With Peritoneal Dialysis
Assessment of Bioimpedance and Vitamin D and LV Mass in PD Patients (FLUID Study)
The main purpose of this study is to compare the effects of using bio-impedance analysis to guide management of fluid status versus routine clinical care on heart structure.
- Trial name
- FLUID (NCT01045980)
- Testing
- Bioimpedance and Vitamin D, Usual care and Vitamin D
- Where
- 2 sites in Canada
- Volunteers
- 74 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Kidney Transplantation
Stroke Volume Variation and Pulse Pressure Variation as Predictors of Fluid Responsiveness During Kidney Transplantation
The aim pf this prospective study is to investigate the ability of stroke volume variation (SVV) and pulse pressure variation (PPV) to predict fluid responsiveness in patients undergoing kidney transplantation.
- Trial name
- NCT02459470
- Testing
- Fluid loading
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Samsung Medical Center
Secondary Progressive Multiple Sclerosis
MS-SMART: Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial
Multiple sclerosis (MS) is a disabling and progressive neurological disease that affects approximately 100,000 people in the UK.
- Trial name
- MS-SMART (NCT01910259)
- Testing
- Amiloride, Riluzole, Fluoxetine
- Where
- 13 sites in United Kingdom
- Volunteers
- 445 people
- Sponsor
- University College, London
Circulatory Failure / Shock State, Fluid Therapy
Metabolic Fluid Responsiveness in Children
The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery.
- Trial name
- METAFRIC (NCT07255469)
- Where
- 8 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Bordeaux
Gastric Residual Volume
Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries
General Anesthesia requires preoperative fasting according to specific instructions. Regarding Fasting Guidelines, The American Society of Anesthesiologists (ASA) recommends patients to fast from fatty food or meat eight hours…
- Trial name
- NCT05570292
- Testing
- Domperidone, Folic acid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Shock
Impact of Amount of Fluid for Circulatory Resuscitation on Renal Function in Patients in Shock
Volume resuscitation is the mainstay of treatment in most types of shock, especially in hemorrhagic and septic shock. Septic shock is a main cause of morbidity and mortality worldwide.
- Trial name
- VoluKid (NCT02666404)
- Testing
- Measurement
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University Hospital, Basel, Switzerland
Sepsis, Hypotension
Fluid Responsiveness Evaluation in Sepsis-associated Hypotension
This study assesses the mean difference in fluid balance at ICU discharge and associated patient outcomes, based on a dynamic assessment of fluid responsiveness in septic patients with refractory hypotension in an ICU setting.
- Trial name
- FRESH (NCT02837731)
- Testing
- Treatment Starling SV monitor
- Where
- 12 sites in United States, United Kingdom
- Volunteers
- 150 people
- Sponsor
- Cheetah Medical Inc.
Stroke Volume Variation, SVV-FloTrac
A Comparison of Stroke Volume Variation for Prediction of Fluid Responsiveness
Stroke volume variation (SVV) is an indicator used to assess the patient's volume status. The FloTrac system (Edwards Lifesciences, Irvine, CA) continuously monitors cardiac output (CO) and SVV (SVV-FloTrac) by analyzing the…
- Conditions
- Stroke Volume Variation, SVV-FloTrac, Thoracic Electrical Bioimpedance, Fluid Responsiveness
- Trial name
- NCT06215157
- Testing
- Flotrac Group, BioZ Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Major Abdominal Surgery, Duodenohemipancreatectomy
Intraoperative Haemodynamic Optimization Comparing Flow and Pressure Parameters
The purpose of the study is to confirm the hypothesis that flow treatment algorithm based on cardiac index trending by transesophageal Dopplerometry would result in reduced complications and reduced length of hospital stay in…
- Conditions
- Major Abdominal Surgery, Duodenohemipancreatectomy, Rectal Resection, Extensive Bowel Surgery
- Trial name
- Flow-press (NCT02104687)
- Testing
- Flow group, Press group
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Ostrava
Weight Gain
Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis , Full Scale Trial
Methods are needed to help decrease interdialytic weight gains in hemodialysis patients. One potential method for accomplishing this goal is to develop an app for smartphones that allow patients to track their fluid intake…
- Trial name
- NCT04194164
- Testing
- Fluid intake app
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Hydrocephalus
Randomized Controlled Trial of Shunt vs ETV/CPC for PIH in Ugandan Infants
Two treatment options exist for infant patients with hydrocephalus. Most patients are treated with a surgical procedure in which a shunt is inserted into the brain and abdomen.
- Trial name
- NCT01936272
- Testing
- Chhabra Shunt Placement, ETV/CPC
- Where
- Uganda
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Hypovolemia, Hypotension
Dynamic Parameters in Evaluation of Fluid Responsiveness
Intravenous infusion of fluids in patients after surgery is a very important part of treatment. However, administering too much or too little fluid can lengthen the stay in the intensive care unit or even harm the patient.
- Conditions
- Hypovolemia, Hypotension, Surgery
- Trial name
- NCT04283851
- Testing
- testing functional haemodynamic parameters for preload assessment
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Baseline, Hemodilution
Performance of Non-Invasive Monitors During ANH
The aim of this study is to assess the responsiveness of the standard minimally invasive hemodynamic monitors used in the operating room to known changes in the intravascular volume status that occur during blood removal and…
- Trial name
- NCT02179827
- Where
- United States
- Sponsor
- University of California, Davis
Hypovolemia, Hemorrhage
Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients
The Pressure Recording Analytical Method, invasive hemodynamic monitoring, is an uncalibrated pulse contour analysis, installed in the Mostcare® system that allows a continuous estimation of the stroke volume and thus the cardiac…
- Conditions
- Hypovolemia, Hemorrhage, Fluid Responsiveness
- Trial name
- MOSTCARE-PED (NCT04186416)
- Testing
- Mostcare® device, Transthoracic cardiac ultrasound
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Emptying Time
Gastric Emptying Times of Normal and Obese Children After Preoperative Clear Fluid Drinking: An Ultrasound Study
In the recent literature, pre-operative fasting times for pediatric patients are limited to one hour for clear fluids. Studies related to gastric emptying times mostly searched for normal-weight children.
- Trial name
- NCT05244902
- Testing
- 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Karaman Training and Research Hospital
Coronary Artery Bypass Grafting, Fluid Therapy
Comparison of Dynamic Fluid Responsiveness by EIT and Transpulmonary Thermodilution in Postoperative of CABG Patients
The purpose of this study is to evaluate the stroke volume variation measured by both methods: transpulmonary thermodilution and electrical impedance tomography (EIT), during fluid responsiveness maneuvers and after fluid…
- Conditions
- Coronary Artery Bypass Grafting, Fluid Therapy, Stroke Volume, Hemodynamic Monitoring
- Trial name
- NCT04362033
- Testing
- Passive Leg Raising (PLR) and PEEP increment (PEEP)
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Ludhmila Abrahão Hajjar