Clinical trials: Vaccination Failure
Vaccination Failure
Timeliness and Completeness of Routine Childhood Vaccinations by 2 Years of Age in Nigeria.
The timeliness of routine childhood immunization should be an important component in measuring vaccination coverage rates especially in LMIC countries like Nigeria, yet this is overlooked.
- Trial name
- NCT03792022
- Testing
- Adherence to timely vaccine uptake
- Volunteers
- 1,800 people
- Sponsor
- Lifespan Healthcare Resource Limited
RENAL INSUFFICIENCY, CHRONIC, LIVER FAILURE, ACUTE
Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant
A prospective, multisite study to evaluate the Impact of Measles, Mumps, Rubella and Varicella ProQuad® vaccination in pediatric patients 6-24 months of age who are being considered and/or evaluated for any solid organ transplant…
- Conditions
- RENAL INSUFFICIENCY, CHRONIC, LIVER FAILURE, ACUTE, HEART DISEASE
- Trial name
- ProQuad® (NCT02687763)
- Testing
- ProQuad
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Chronic Heart Failure
Impact of a Letter Encouraging Pneumococcal Vaccination on the 1-year Vaccination Rate in Heart Failure Patients With a Primary Care Physician
Heart failure affects more than 1.5 million people in France, resulting in over 70,000 deaths and more than 165,000 hospitalizations each year.
- Trial name
- NCT06360315
- Testing
- Incentive letter for pneumococcal vaccination to the patient and to the GP
- Where
- France
- Volunteers
- 12,000 people
- Sponsor
- University Hospital, Montpellier
Chronic Respiratory Failure, Tracheostomy Complication
Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
This study involves conducting a telephonic or in person survey regarding parental perception and attitudes about vaccinating the respective "technology dependent" child with the COVID 19 vaccination.
- Conditions
- Chronic Respiratory Failure, Tracheostomy Complication, Mechanical Ventilation Complication
- Trial name
- NCT05084976
- Testing
- COVID 19 vaccine counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Non-hodgkin Lymphoma,B Cell, Vaccination Failure
Immune Response After SARS-CoV-2 (COVID-19) Vaccination in a Context of Non-Hodgkin Lymphoma
The specific immune response to SARS-CoV-2 includes a humoral response - specific IgM appearing 5 days after the onset of symptoms while IgG appears after 14 days - and a T lymphocyte component, with specific activated CD8 and…
- Trial name
- LYMPHO-CoVac (NCT05050461)
- Testing
- Immunological analyses
- Where
- 7 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Versailles Hospital
Hepatitis B Infection
Evaluation of Paternal, Maternal and Obstetric Factors Leading to the Hepatitis B Immunization Failure in Hong Kong
Globally, hepatitis B virus (HBV) infection is the most common form of chronic hepatitis. There are still a lot of uncertainties on how infants acquired HBV leading to the development of chronic HBV infection despite active and…
- Trial name
- NCT02443233
- Where
- China
- Volunteers
- 750 people
- Sponsor
- The University of Hong Kong
COVID-19, Vaccination
COVID-19 Vaccination AZV 2021-2023
The study is aimed at the clinical and laboratory characteristics of patients with completed vaccination against SARS-CoV-2 admitted to the hospital in the standard ward and intensive care unit due to the severe course of…
- Conditions
- COVID-19, Vaccination, Immunity, Respiratory Failure
- Trial name
- NCT05589233
- Testing
- Vaccionation eighter started or full course
- Where
- Czechia
- Volunteers
- 3,000 people
- Sponsor
- University Hospital Hradec Kralove
Acute Coronary Syndrome, Heart Failure
Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)
The aim of this study is to evaluate the effect of offering intrahospital influenza vaccination as an adjunct to active counseling during the index hospitalization to adult patients hospitalized for acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Heart Failure, Influenza, Human, Cardiovascular Diseases
- Trial name
- VACC-UP (NCT07721649)
- Testing
- Intrahospital seasonal influenza vaccination offer, Standardized active influenza vaccination counseling, Standard of care discharge recommendation for ambulatory vaccination
- Where
- 2 sites in Germany
- Volunteers
- 482 people
- Sponsor
- Stephan Baldus
Vaccination; Infection
Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Patients With Chronic Renal Failure
Immune response to influenza vaccine in patients with chronic renal insufficiency.
- Trial name
- CHRONOVAX2 (NCT06907667)
- Testing
- Vaccine injection
- Where
- France
- Volunteers
- 735 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Covid19, Vaccine Reaction
Protective Antibody Level After COVID-19 Vaccination Among Patients Under Hemodialysis
The aim of the study is to evaluate the level of neutralizing antibody against SARS-CoV-2 after COVID-19 vaccination in patients under hemodialysis.
- Conditions
- Covid19, Vaccine Reaction, Hemolysis, End-stage Renal Disease
- Trial name
- NCT04871945
- Testing
- Elecsys Anti-SARS-CoV-2 S (Roche Diagnostics GmbH, Mannheim, Germany), 2) ACCESS SARS-CoV-2 IgG II (Beckman Coulter, Inc. USA)
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hanyang University Seoul Hospital
Immunology, Nephrology
Immune Response to Influenza Vaccine in ESRD Patients
On-line hemodiafiltration (HDF) clears more azotaemic toxins compared to high-flux hemodialysis (HD). The response to vaccination is impaired in dialysis patients.
- Trial name
- NCT04122222
- Testing
- Influenza vaccine
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Cardiovascular Diseases, Atrial Fibrillation
A Digital Flu Intervention for People With Cardiovascular Conditions
A 6-month prospective, digital randomized controlled trial targeting approximately 49,000 individuals to evaluate the effectiveness of an influenza vaccination intervention during influenza season for people with cardiovascular…
- Conditions
- Cardiovascular Diseases, Atrial Fibrillation, Abnormal Heart Rhythms, Cardiac Arrest
- Trial name
- CardioFlu (NCT04584645)
- Testing
- Targeted digital intervention
- Where
- United States
- Volunteers
- 49,138 people
- Sponsor
- Evidation Health
Heart Failure
Flu Vaccination in Congestive Heart Failure
We evaluated the preventive impact of vaccination on subsequent death events in 117 severe congestive heart patients requiring ventilator support without endotracheal intubations and aggressive medical therapy.
- Trial name
- FLUVACS-IC (NCT00664339)
- Testing
- Flu Vaccine, Conventional medical therapy for heart failure
- Volunteers
- 117 people
- Sponsor
- La Fundacion Favaloro para la Investigacion y la Docencia Medica
Chronic Kidney Failure
13 Valent Pneumococcal Conjugate Vaccine in Chronic Dialysis Patients
To assess the immunogenicity of the PCV13 (13 valent pneumococcal conjugated vaccine) vaccine as compared to the PPV23 (23 valent pneumococcal polysaccharide vaccine) vaccine in patients treated with chronic hemodialysis that are…
- Trial name
- NCT02492438
- Testing
- PPV23 vaccination or PCV13 vaccination
- Where
- 2 sites in Belgium
- Volunteers
- 154 people
- Sponsor
- AZ Sint-Jan AV
Vaccination Failure
Automated SMS Reminders to Parents on Their Cell Phones Can Significantly Improve the on Time Vaccination Rates Children in Pakistan
The investigators plan to test the effectiveness of reminders to parents/guardians on cell phones through short messaging system (SMS) in improving the on-time routine immunization for children in Pakistan.
- Trial name
- NCT01908946
- Testing
- SMS reminders
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Heart Failure
Vaccination Against Influenza Pre-discharge in Heart Failure
In patients with heart failure (HF), influenza vaccination should be considered to prevent HF hospitalizations. However, vaccination rates among patients with HF are low, in part because of subjective but common concerns about…
- Trial name
- NCT06725927
- Testing
- Influenza vaccination
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Wroclaw Medical University
Myocardial Infarction, Decompensated Chronic Heart Failure
Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions
Patients hospitalized for acute cardiac conditions-including acute myocardial infarction, acute heart failure, pulmonary embolism, arrhythmias, and hypertensive emergencies-represent a heterogeneous population at very high risk…
- Conditions
- Myocardial Infarction, Decompensated Chronic Heart Failure, Acute Heart Failure (AHF), Pulmonary Embolism Acute
- Trial name
- NCT07617376
- Testing
- Influenza vaccination
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Wroclaw Medical University
Liver Transplantation, Graft Failure
Immunization Anti HLA in the Liver Transplant Recipients (DSATH)
Anti HLA alloimmunization against the donor evaluated by the detection of anti-donor specific antibodies (DSA) is an underestimated factor in liver transplantation and may contribute to dysfunction and graft loss , especially…
- Trial name
- DSATH (NCT02556879)
- Testing
- Donor specific antibodies, Serum bank, DNA bank
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diarrhoea
Causes of Rotavirus Vaccine Failure in Zambian Children
Zambia recently introduced routine infant immunization against rotavirus - the most important cause of severe gastroenteritis and diarrhoea mortality in children.
- Trial name
- NCT01886833
- Where
- Zambia
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
End Stage Kidney Disease
Phenotyping Seroconversion Following Vaccination Against COVID-19 in Patients on Haemodialysis Study
Patients on haemodialysis are at higher risk of getting a severe form of COVID-19 if they become infected. Vaccinations are soon to arrive and offer great hope of controlling the current pandemic.
- Trial name
- NCT04815850
- Where
- United Kingdom
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Leicester