Clinical trials: Vaccination Pain
Procedural Pain
A Test of the Effectiveness of a Device and Distraction for Pediatric Immunization Pain
The hypothesis of this study is that distraction cards used by the caretaker along with a vibrating cold pack placed proximal to the site of immunization will decrease the pain of routine pediatric immunizations when compared to…
- Trial name
- NCT01152489
- Testing
- Device: Buzzy
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- MMJ Labs LLC
Pain
Thermal Analgesia in Newborns
Newborns routinely experience pain associated with invasive procedures such as blood sampling, immunization, vitamin K injection, or circumcision.
- Trial name
- NCT00740298
- Testing
- sucrose, warmth
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pain Due to Childhood Vaccination
Distraction and Vibration for Minimizing Pain During Childhood Vaccination
Vaccine pain control is one of the actions suggested to support the delivery of vaccines that are on a vaccine schedule, since pain and anxiety associated with vaccines are among the main reasons why children and their parents…
- Trial name
- NCT03540589
- Testing
- Buzzy specific vibration device, Distraction
- Where
- Brazil
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Hospital Nossa Senhora da Conceicao
Pain, Vaccination Adverse Event
A Study to Assess the Acceptability and Usability of a New Device for Intradermal Vaccination
The aim of this study was to assess the acceptability and usability of a newly developed intradermal device in healthy adults
- Trial name
- NCT01963338
- Testing
- Intradermal injection in the forearm (0,1cc NaCl 0,9%), Intradermal injection in the upper arm (0,1cc NaCl 0,9%), Intramuscular injection in the upper arm (0,5cc NaCl 0,9%)
- Where
- Belgium
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Pierre Van Damme
Vaccination Pain Management
Rotavirus vs. Sucrose for Vaccine Injection Pain
This randomized trial will compare the analgesic effectiveness of oral rotavirus vaccine to sugar water for reducing vaccine injection pain in infants.
- Trial name
- NCT02174705
- Testing
- Sucrose, Rotavirus
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anna Taddio
Pain, Pediatrics
Use of Virtual Reality in the Reduction of Pain After the Administration of Vaccines Among Children in Primary Care Centers.
The objective of this randomized, multicenter, open-label, parallel, controlled clinical trial is to evaluate pain reduction during the administration of two vaccines in children aged 3 and 6 years through virtual reality.
- Conditions
- Pain, Pediatrics, Vaccination, Virtual Reality
- Trial name
- NCT06313762
- Testing
- Pico G2 Virtual Reality Glasses (Pico Interactive Inc), together with an Android AOYODKG tablet, Traditional Distractors, Triple Viral + Varicella Vaccine at 3 years of age
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Pain, Chronic, Whiplash Injury
Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash
With the present study the investigators wish to examine if reconceptualisation of pain, by educating chronic whiplash-associated disorders (CWAD) patients on the neurophysiology of pain, in combination with psychologic…
- Trial name
- NCT01544075
- Testing
- Pain neurophysiology education (PNE) and psychologic inoculation (PI), Neck school (NS)
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Vrije Universiteit Brussel
Procedural Pain, Pain, Acute
The Effect of Facilitated-tucking and ShotBlocker on Pain Caused by Vaccination in Healthy Infants
This study will be investigated the effects of facilitated tucking, ShotBlocker and combined facilitated tucking and ShotBlocker methods on procedural pain, crying time and duration of the procedure during Hepatitis B vaccine…
- Conditions
- Procedural Pain, Pain, Acute, Nursing Caries
- Trial name
- NCT06377748
- Testing
- Facilitated tucking position, ShotBlocker, Combined facilitated tucking and ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Procedural Pain, Vaccination Pain
Cold Spray and Helfer Skin Tap for Pain During Infant Vaccination
This randomized controlled experimental study aims to evaluate the effects of cold spray and the Helfer Skin Tap technique on pain levels during intramuscular pneumococcal conjugate vaccine administration in 12-month-old infants.
- Conditions
- Procedural Pain, Vaccination Pain, Injection Pain
- Trial name
- NCT07779681
- Testing
- Cold spray, Helfer Skin Tap Technique
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hitit University
Pain, Quality of Life
FLUAD® vs. Fluzone® High-Dose Study
The overall aim of the study is to compare safety and immunogenicity of inactivated influenza vaccine (IIV), adjuvanted (FLUAD®) versus High-Dose inactivated influenza (Fluzone® High-Dose) vaccine in persons ≥65 years (20% aged…
- Conditions
- Pain, Quality of Life, Injection Site Reaction, Side Effect of Drug
- Trial name
- NCT03183908
- Testing
- FLUAD®, Fluzone® High-Dose
- Where
- 4 sites in United States
- Volunteers
- 757 people, healthy volunteers welcome
- Sponsor
- Duke University
Pain, Quality of Life
Simultaneous RZV and aIIV4 Vaccination
The overall aim of the study is to compare the safety of simultaneous Zoster Vaccine Recombinant, Adjuvanted (RZV) (SHINGRIX®) and Quadrivalent Influenza Vaccine, Adjuvanted (FLUAD®) versus simultaneous Zoster Vaccine…
- Conditions
- Pain, Quality of Life, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05007041
- Testing
- FLUAD® Quadrivalent, Fluzone® High-Dose Quadrivalent, SHINGRIX®
- Where
- 2 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Duke University
Fear, Fear of Pain
Effect of Using Educational Robots During Vaccination on Fear and Pain in Children
Pain and fear are very common in children during vaccination. We are planning to conduct a study to help children go through this process more comfortably.
- Conditions
- Fear, Fear of Pain, Pain, Vaccination
- Trial name
- NCT06856395
- Testing
- intervention group
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Vaccine Reaction
Infant Pain During Vaccination and Maternal Anxiety
This research was planned to determine the effect of two different methods on infant pain during vaccination and mother anxiety.The study was planned as a randomized controlled trial.
- Trial name
- NCT05598372
- Testing
- shotblocker, lullaby
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Vaccination, Pain
The Effect of ShotBlocker and Vibration on Pain During Vaccination
This study was conducted to investigate the effects of ShotBlocker and a vibration pen on pain in infants during routine vaccination. In this randomized controlled trial, 96 healthy infants aged 2-6 months were included.
- Conditions
- Vaccination, Pain, Infant, Shotblocker
- Trial name
- NCT07379034
- Testing
- ShotBlocker Group, Vibration Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Intravenous Injections, Vaccination
Efficacy of the Buzzy® Device on the Prevention of Health Care Induced Pediatric Pain in a Vaccination Center
In vaccination centers, venipunctures and vaccinations are sources of pain and anxiety in pediatric patients. Prior painful experiences can reduce the acceptance of later health care, hence making it more difficult for both…
- Trial name
- DOLVAX (NCT03220555)
- Testing
- Buzzy® device, EMLAPATCH (lidocaine, prilocaine)
- Where
- 3 sites in France
- Volunteers
- 220 people
- Sponsor
- Nantes University Hospital
Mothers of Newborn Infants
A Randomized Controlled Trial About Teaching Parents How to Manage Childhood Immunization Pain
There is no effect of a parent-directed fact sheet about pain management during childhood immunization and pre-test on parent learning about evidence-based pain relieving methods.
- Trial name
- NCT01637779
- Testing
- Fact sheet
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Toronto
Pain
Reduction of Immunization Discomfort in Children
A combination of topical anesthetic, plastic arm gripper, visual focusing task and hypnotic suggestions will reduce the discomfort associated with immunization of pre-kindergarten aged children.
- Trial name
- NCT00720824
- Testing
- Topical anesthetic and hypnotic distraction, Office routine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Berberich, F. Ralph, M.D.
Pain, Analgesia
Non-Pharmacologic Interventions to Relief Pain in Healthy Newborns Submitted to Vaccination to Hepatitis B
Acute procedural pain in neonates may be alleviated by non-pharmacological procedures. This study objective is to test the efficacy regarding pain attenuation of 3 interventions (skin-to-skin contact versus glucose 25% versus…
- Trial name
- NCT00713986
- Testing
- Water 2mL PO 2 minutes prior to intra-muscular injection, skin-to-skin contact, Glucose 25% 2 mL PO 2 minutes prior to injection
- Volunteers
- 640 people
- Sponsor
- Federal University of São Paulo
Child, Only
The Effect of the Helper Skin Tap Technique and Buzzy® During Vaccination
Aim: This randomised controlled experimental study was conducted to determine the effect of Helfer Skin Tap Technique and Buzzy® application on the pain level during measles-mumps-rubella-mumps (MMR) vaccine injection in…
- Trial name
- NCT06312228
- Testing
- Helfer Skin Tap, Buzzy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Vaccination
Virtual Reality vs. Standard-of-Care for Comfort During Immunizations in Children
Children need routine immunizations which can be a painful procedure associated with pain and anxiety. This is particularly true of children visiting the children's hospital to visit relatives during flu season.
- Trial name
- NCT03693469
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia