Clinical trials: Vaccine Preventable Disease
Herpes Zoster, Vaccine-Preventable Diseases
A Study to Evaluate Safety and Tolerability of a Recombinant Herpes Zoster Vaccine
This clinical trial is to study the safety and tolerability of a recombinant herpes zoster vaccine (LZ901) and sponsored by Beijing Luzhu Biotechnology Co., Ltd.
- Trial name
- NCT05750017
- Testing
- Low Dose Recombinant Herpes Zoster Vaccine (LZ901), High Dose Recombinant Herpes Zoster Vaccine (LZ901)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Beijing Luzhu Biotechnology Co., Ltd.
HPV, Vaccine-Preventable Diseases
Playing Game to Learn About Children's Vaccine Project
This proposed study aims to conduct timely research that promotes vaccine confidence and vaccination of one strongly recommended vaccine with suboptimal uptake rates: Human papillomavirus (HPV) in vulnerable and underserved youth…
- Trial name
- NCT05984849
- Testing
- vaccination game
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Pneumococcal Infections, Chronic Lymphocytic Leukemia
Pneumococcal Vaccination in Patients With Chronic Lymphocytic Leukaemia
In this study the antibody response after vaccination with the 13-valent pneumococcal conjugated vaccine (PCV13) followed 2 months later by the 23-valent polysaccharide vaccine (PPSV23) in adults with chronic lymphocytic leukemia…
- Conditions
- Pneumococcal Infections, Chronic Lymphocytic Leukemia, Vaccine-Preventable Diseases, Invasive Pneumococcal Disease, Recurrent Isolated
- Trial name
- Pneumo-CLL (NCT05145101)
- Testing
- Prevnar13
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Hannah Garcia Garrido
Japanese Encephalitis, Vaccine Preventable Disease
Seroprevalence of Neutralizing Antibodies Against Japanese Encephalitis Virus Among 6 Years Old Children With 5 Different Immunization Strategies in Zhejiang Province
This study is to evaluate the seroprevalence of neutralizing antibodies against Japanese encephalitis (JE) virus in children aged 6 years who were previously administered with 5 different immunization strategies by JE attenuated…
- Conditions
- Japanese Encephalitis, Vaccine Preventable Disease, Vaccine Reaction
- Trial name
- NCT04817917
- Testing
- Japanese Encephalitis Vaccine (Vero Cell), Inactivated;, No prospective interventions
- Where
- 3 sites in China
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Patient Engagement, COVID-19
Collaborative Open Research Initiative Study (CORIS-1)
The Collaborative Open Research Initiative Study (CORIS) is a groundbreaking international research endeavor aimed at exploring vital topics within the field of health professions education.
- Conditions
- Patient Engagement, COVID-19, Preventable Disease, Vaccine, Burnout, Professional
- Trial name
- CORIS-1 (NCT06357650)
- Testing
- No intervention. This is an observational study
- Volunteers
- 15,000 people
- Sponsor
- Chisquares Incorporated
Vaccine-Preventable Diseases, Influenza
Safety and Immunogenicity of Two Dose Levels of OVX836 Influenza Vaccine as a Booster on Participants Previously Administered With OVX836
This phase 2a is designed to evaluate the anamnestic response of a booster dose (either 180 µg or 480 µg) of OVX836 influenza vaccine administered intramuscularly to participants vaccinated three to five years ago in OVX836-002…
- Trial name
- NCT06582277
- Testing
- OVX836 shot
- Where
- Belgium
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Osivax
Covid19, Non-specific Effects of Vaccines
Using BCG to Protect Senior Citizens During the COVID-19 Pandemic
Background: The virus SARS-CoV-2 has spread rapidly throughout the world. Seniors are at high risk of severe COVID-19 when infected.
- Conditions
- Covid19, Non-specific Effects of Vaccines, Heterologous Immunity, Morbidity
- Trial name
- NCT04542330
- Testing
- BCG-Denmark, Saline
- Where
- Denmark
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Vaccine-Preventable Diseases
An Evaluation of a Dynamic Web-Based Visualization of Community Immunity
This study is a PhD project conducted by Ms. Hina Hakim, supervised by Dr. Holly O. Witteman, PhD, and co-supervised Dr. Daniel Reinharz, professors and researchers at the Faculty of Medicine at Laval University.
- Trial name
- NCT04787913
- Testing
- herdimm, guardianmeasles, theotheredmundmeasles
- Where
- Canada
- Volunteers
- 5,516 people, healthy volunteers welcome
- Sponsor
- Laval University
Vaccine-Preventable Diseases
Animal Bite Victims Seeking Medical Services at Concerned Hospitals
The goal of this observational study is to study the magnitude of the animal bite problem during one year ,to determine the percentage of compliance for full PEP doses and factors affecting the health seeking behavior among these…
- Trial name
- NCT06054581
- Testing
- health seeking behavior
- Volunteers
- 662 people
- Sponsor
- Assiut University
Immunization; Infection
Mobile Phone Reminders (and Photovoice) for Routine Immunization in Nigeria - The MOPING Study
This study aims to implement and test the efficacy of photovoice, Short Messaging Service (SMS) and phone call reminders in improving childhood immunization coverage (uptake, timeliness and completion rates) and reducing…
- Trial name
- MOPING (NCT03402646)
- Testing
- Reminder module (SMS and Phone call), Photovoice
- Volunteers
- 1,813 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Meningococcal Disease; Meningococcal Meningitis
Single-center, Open-label Study: Immunogenicity and Safety Observation After Vaccination With ACYW135 Meningococcal Polysaccharide Vaccine in Junior High School Students Aged 13-15 Years
The sample size of this study is 200 participants, aiming to evaluate the protective effect after vaccination with quadrivalent meningococcal polysaccharide vaccine in the 13-15 age group, and to provide scientific evidence and…
- Trial name
- NCT07885371
- Testing
- MPSV-ACYW
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Human Papilloma Virus, Vaccine-Preventable Diseases
Hashtag HPV: HPV Vaccine Twitter Education Program
Parents use social media as an important parenting tool and source for health information. Using social media data to examine public opinion has had an early impact in public health and in cancer control and prevention efforts…
- Trial name
- NCT05204030
- Testing
- HPV Twitter Education Program - Narrative, HPV Twitter Education Program - Non-Narrative
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Vaccine Preventable Disease
COVID-19 Antibody Levels After Vaccines
This study will measure the levels of nasal mucosal Immunoglobulin A (IgA) and blood serum IgA up to one year after COVID vaccination, as well as examining what factors might affect antibody levels in the nose.
- Trial name
- NCT04944134
- Testing
- COVID-19 Vaccination
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
Iron Deficiency Anemia, Vaccine Preventable Disease
Iron and Vaccine Response
Vaccines often underperform in Africa compared to high-income countries. Why vaccines do not work as well in Africa remains uncertain. Malnutrition likely plays a role.
- Conditions
- Iron Deficiency Anemia, Vaccine Preventable Disease, Vaccine Response Impaired, Iron Deficiency Anemia Treatment
- Trial name
- NCT04912661
- Testing
- Ferinject
- Where
- Kenya
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Plague, Pneumonic, Plague
Trial of the Immunogenicity, Safety, and Tolerability of rF1V Vaccine With CpG 1018® Adjuvant Compared With rF1V Vaccine in Adults 18 to 55 Years of Age
Phase 2, Randomized, Active-Controlled, Observer-Blinded, Multicenter Trial of the Immunogenicity, Safety, and Tolerability of rF1V Vaccine with CpG 1018® Adjuvant Compared with rF1V Vaccine in Adults 18 to 55 Years of Age
- Conditions
- Plague, Pneumonic, Plague, Vaccine-Preventable Diseases
- Trial name
- NCT05506969
- Testing
- rF1V-1018, rF1V vaccine
- Where
- 6 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dynavax Technologies Corporation
HPV, HPV Vaccination
Impact of Catch-up HPV Vaccination
Each year in France, more than 6000 new cases of HPV inducted cancers are recorded. The vaccinal cover stays insufficient since less than 30% of the french population is vaccinated.
- Conditions
- HPV, HPV Vaccination, Vaccine Preventable Disease, Cervical Lesion
- Trial name
- HPVAC2 (NCT05462249)
- Where
- France
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Vaccine Preventable Disease
COVID-19 Vaccine For Indirect Protection
The primary objective of this study is to test whether vaccinating adults ≥18 years in Hutterite colonies with mRNA-1273 (Moderna COVID-19) vaccine as compared to control (usual care) can prevent RT-PCR confirmed COVID-19 in…
- Trial name
- NCT04818736
- Testing
- COVID-19 Vaccination, Usual care
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
AIDS/HIV - RelatedDisease Associated With AIDS, Vaccine-Preventable Diseases
Study to Evaluate the Safety and Immunogenicity of an HIV-1 Vaccine Regimen of Adjuvanted UVAX-1107 Followed by Adjuvanted UVAX-1107 or Adjuvanted UVAX-1197 in Healthy Subjects Aged 25-55 Years.
This is a first in human testing of novel HIV-1 protein nanoparticles vaccine candidates, UVAX-1107 and UVAX-1197 mixed with Aluminum Hydroxide (AH) and CpG 1018 adjuvants.
- Conditions
- AIDS/HIV - RelatedDisease Associated With AIDS, Vaccine-Preventable Diseases, HIV Infections
- Trial name
- NCT06541093
- Testing
- UVAX-1107, UVAX-1197
- Where
- Australia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Uvax Bio LLC
Vaccine-Preventable Diseases, Hepatitis B
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Prophylactic Hepatitis B Vaccine
The purpose of this study is to evaluate the safety and immunogenicity of the investigational medicinal product, CVI-HBV-002.
- Trial name
- CVI-HBV-002 (NCT06147895)
- Testing
- CVI-HBV-002
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aribio Lab Co., Ltd.
Colon Cancer, Lung Cancer
Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and LivER Cancer
The purpose of CLOVER is to utilize Epic Healthy Planet to increase adherence to United States Preventive Services Task Force (USPSTF) and Centers for Disease Control and Prevention (CDC) recommendations in adults age 50 and…
- Conditions
- Colon Cancer, Lung Cancer, Tobacco Use Cessation, Obesity
- Trial name
- CLOVER (NCT04540081)
- Testing
- Epic Healthy Planet Population Health Module
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- University of California, Davis