Clinical trials: Vaccine Reaction
COVID-19, Vaccine Reaction
A Real-world Study to Evaluate the Safety and Immunogenicity of a Third-dose Booster After Two Doses of an Inactivated COVID-19 Vaccine
This project is a prospective observational real-world study, recruiting and screening subjects who have completed 2 doses of the COVID-19 vaccine for more than 6 months and receive the third dose of the vaccine voluntarily into…
- Trial name
- NCT05493917
- Testing
- an inactivated SARS-CoV-2 vaccine named BBIBP-CorV
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Yellow Fever Vaccination Reaction
Study of the Safety and Immunogenicity of Reduced Doses of the US Yellow Fever Vaccine
This is an open-label, randomized, exploratory study to evaluate the human immune response to reduced subcutaneous (SQ) dosing of Yellow Fever vaccine compared to the standard FDA approved subcutaneous vaccination dose.
- Trial name
- NCT05374317
- Testing
- Yellow Fever Vaccine
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- US Army Medical Research Institute of Infectious Diseases
COVID-19, Vaccine Reaction
Evaluation of Inactivated Vaccine in Healthy Adults Against Coronavirus Disease of 2019 (COVID-19)
In this phase 1 study, the inactivated virus vaccine National Research Centre (NRC) Vaccine-101 (VACC-101) will be investigated for its safety and immunogenicity in healthy volunteers with the aim of providing effective and safe…
- Conditions
- COVID-19, Vaccine Reaction, Vaccine Adverse Reaction
- Trial name
- NCT05128721
- Testing
- Covi Vax
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Vaccine Reaction
SARS-CoV-2 Antibodies and Virus Neutralisation in a Cohort Vaccinted Against COVID-19
Analysis of SARS-CoV-2 antibodies and serum virus neutralisation in vaccinated heath care personnel. Analysis of virus neutralisation as a function of age, gender, and history of COVID-19 infection.
- Trial name
- DER-CoV2-001 (NCT04979871)
- Testing
- Venous bleeding
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
LTBI, BCG Vaccination Reaction
Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI)
TB-reactive immune cells will be tested in a multiparametric flow cytometry to distinguish an immune response for antigens of Mycobacterium spp. in TB disease/latent infection or a reaction after BCG vaccine.
- Conditions
- LTBI, BCG Vaccination Reaction, TB
- Trial name
- NCT04673227
- Testing
- Blood draw
- Where
- 2 sites in Czechia
- Volunteers
- 120 people
- Sponsor
- Thomayer University Hospital
Adverse Reaction to Cholera Vaccine, Cholera Vaccination Reaction
Extended Dose Intervals With Oral Cholera Vaccine in Cameroon
The primary aim of this project is to determine changes in the vibriocidal geometric mean titers (GMT) in subjects who receive the second dose of oral cholera vaccine (OCV) at different intervals: 2 weeks, 6 months, or 11 months…
- Trial name
- NCT03719066
- Testing
- killed whole cell oral cholera vaccine
- Where
- Cameroon
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cirrhosis, Liver, Vaccination Failure
Evaluation of Intradermal Hepatitis B Vaccine After IMIQUIMOD's Application, in Cirrhotics Who Did Not Respond to the Usual Vaccine Regimen
In a population of cirrhotics patients who did not responde to an anti-HBV vaccination according to the recommended vaccination, the goal is to : Describe the proportion of patients with HBs antibody levels greater than 10mUI/mL…
- Conditions
- Cirrhosis, Liver, Vaccination Failure, HBV, Vaccine Reaction
- Trial name
- IDMODVHB (NCT05028322)
- Testing
- IMIQUIMOD cream, HEPATITIS B SURFACE ANTIGEN
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Anaphylactic Reaction, Vaccine Reaction
Allergy and COVID-19 Vaccines
Prospective and retrospective multicenter study to estimate the proportion of patients who tolerated continuation of COVID-19 vaccination (absence of anaphylactic manifestations).
- Trial name
- COVALL (NCT05028257)
- Testing
- COVID-19 Vaccines
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Vaccine Adverse Reaction
Transverse Myelitis Related to SARS-CoV-2 Vaccines
Few patients receiving SARS-CoV-2 vaccines may experience rare but serious adverse events such as transverse myelitis (TM). Today, data about TM are scarce.
- Trial name
- NCT05178264
- Testing
- SARS-CoV-2 vaccines
- Where
- France
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Vaccine Reaction, Vaccine Adverse Reaction
Immunogenicity and Safety Following In-House Recombinant Hepatitis B Vaccine in Indonesian Population (Phase III)
This is a phase 3, experimental, randomized, observer-blind, lot to lot consistency study. The primary objective of this study is to assess the protectivity of In-House Recombinant Hepatitis B vaccine 28 days after 3 doses…
- Trial name
- NCT05482295
- Testing
- In-House Recombinant Hepatitis B (Bio Farma) vaccine, Registered Hepatitis B vaccine recombinant (Engerix-B)
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
COVID-19 Vaccine Adverse Reaction
Assessment of Safety and Satisfaction Toward COVID-19 Vaccines.
This is a cross-sectional, web-based online survey done with the use of a Google Form-questionnaire to gather information from the general public regarding their knowledge, satisfaction, and tolerability about the COVID-19…
- Trial name
- NCT05857176
- Testing
- COVID-19 Vaccine questionnaire
- Where
- Egypt
- Volunteers
- 508 people
- Sponsor
- Damanhour University
COVID-19, Vaccine Immune Response
COVID-19 Vaccine Reactogenicity and Immunogenicity
Analysis of antibody kinetics after vaccination with mRNA-1273 and factors influencing the vaccine immunogenicity
- Conditions
- COVID-19, Vaccine Immune Response, Vaccine Adverse Reaction
- Trial name
- NCT05258708
- Testing
- mRNA-1273 COVID-19 vaccine
- Where
- 5 sites in South Korea
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Vaccine Reaction
Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children
This study is to evaluate the immunogenicity and safety of DTaP or DT given in children aged 6 years.
- Trial name
- DTaP/DT (NCT05870618)
- Testing
- vaccinate with DTap, vaccinate with DT
- Where
- 2 sites in China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Zoster, Systemic Lupus Erythematosus
Immunogenicity, Reactogenicity of Shingrix in SLE
To investigate the immunogenicity, reactogenicity and safety of 2 doses of the adjuvanted herpes zoster subunit vaccine (Shingrix) in patients with SLE in a randomized trial.
- Conditions
- Zoster, Systemic Lupus Erythematosus, Vaccine Reaction
- Trial name
- NCT06001606
- Testing
- Shingrix
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Seoul National University Hospital
Poliomyelitis, Vaccine Reaction
Study to Evaluate Eupolio(IPV)'s Safety, Long-term Protective Effect and Boosting Effect of One Booster Dose in the Three Primary Vaccination Plus Boosting Schedule, and Protective Effect in the Schedule With Bivalent OPV in Infants
Eupolio is inactivated poliovirus vaccine (IPV). Major purpose of this study is to evaluate safety of Eupolio in 2,000 infants. In addition to the safety, long-term protection after completion of the three primary vaccinations…
- Trial name
- NCT05431933
- Testing
- Eupolio
- Where
- 10 sites in Philippines, Thailand
- Volunteers
- 2,001 people, healthy volunteers welcome
- Sponsor
- LG Chem
Covid19, Vaccine Reaction
SARS-CoV-2 (Covid-19) RBD Antibody in My Duc Hospital Healthcare Workers
To evaluate the immune response to the ChAdOx1 nCoV-19 vaccine by measuring the titers of antibody against the SARS-CoV-2 spike protein receptor binding domain (RBD) among healthcare workers of My Duc Hospital and investigate…
- Trial name
- NCT05057910
- Testing
- SARS-CoV-2 IgG II Quant
- Where
- Vietnam
- Volunteers
- 645 people
- Sponsor
- Mỹ Đức Hospital
Vaccination Reaction, Vaccination Pain
CARD for Community Pharmacy Vaccinations
To integrate CARD in community pharmacy-led vaccinations and document impact on vaccine clients and pharmacy staff.
- Conditions
- Vaccination Reaction, Vaccination Pain, Community Pharmacy
- Trial name
- NCT06098703
- Testing
- CARD (Comfort Ask Relax Distract)
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vaccine Reaction
Safety and Immunogenicity of HPV Vaccine Administered Intradermally and Intramuscularly Via Needle-Free Injection System
The goal of this clinical trial is to evaluate the safety and immunogenicity of an HPV Vaccine (Gardasil) delivered by intramuscular needle-free injection and intradermal needle-free injection.
- Trial name
- NCT06142461
- Testing
- Gardasil, PharmaJet Stratis® Needle-Free Injection System, PharmaJet Tropis® Needle-Free Injection System
- Where
- Indonesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Kidney Diseases, Kidney Transplant; Complications
Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.
Prospective observational trial to assess immunological safety (anti-HLA antibodies, donor-derived cell-free DNA) and immunological effectiveness (anti-SARS-CoV-2 IgG) of the first booster dose of SARS-CoV-2 mRNA vaccines in…
- Conditions
- Kidney Diseases, Kidney Transplant; Complications, COVID-19, Vaccine Adverse Reaction
- Trial name
- NCT05483725
- Testing
- Booster dose of mRNA vaccine
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Institute for Clinical and Experimental Medicine