Clinical trials: Vagal Nerve Stimulation
Healthy Subjects (HS)
Vagus Nerve Stimulation for Reaction Time
Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed…
- Trial name
- NCT07528742
- Testing
- vagus nerve stimulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Alzheimer Disease, Aging
Vagus Nerve Stimulation to Enhance Memory in Aging
The aim of this study is to determine whether non-invasive vagus nerve stimulation enhances memory formation in cognitively healthy older adults and whether the effects of stimulation depend on gut and brain health.
- Trial name
- VNS (NCT07214194)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stanford University
Vagus Nerve Stimulation
Transcutaneous Auricular Vagus Nerve Stimulation Prevents Postoperative Delirium in Elderly Patients
According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving taVNS.The results are expected to provide evidence of the safety and efficacy of…
- Trial name
- Vnstar (NCT06421077)
- Testing
- transauricular auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 1,776 people
- Sponsor
- Beijing Tiantan Hospital
Atrial Fibrillation
Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib
Patients undergoing cardiac surgery are at high risk of developing atrial fibrillation (AF), with estimated rates of 30-50% and occurs at approximately 2-4 days after surgery.
- Trial name
- STOP_AF (NCT04514757)
- Testing
- active tVNS
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of California, Los Angeles
Traumatic Brain Injury, Hearing Loss
Improving Speech in Noise Using Noninvasive Stimulation
Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments.
- Trial name
- NCT07176936
- Testing
- Cymba Conchae stimulation, Earlobe stimulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Florida
Health People, Physical Activity
The Effect of Auricular Vagus Nerve Stimulation and Controlled Breathing Exercises on Performance and Autonomic Nervous System
There are many studies in the literature on transcutaneous vagus nerve stimulation (VNS) and controlled breathing exercises (CBE), but there are limited studies examining the effects of both interventions on performance and the…
- Conditions
- Health People, Physical Activity, Autonomic Nerveus System, Vagus Nerve Stimulations
- Trial name
- NCT06796101
- Testing
- Vagus Nerve Stimulation, Controlled breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Pain, Acute
Transauricular Vagal Nerve Stimulation, Pressure Pain and Interoception
Interoception, the ability to perceive, process and respond to signals originating from within the body, is crucial for maintaining healthy physiological ranges.
- Trial name
- NCT06240026
- Testing
- taVNS, Earlobe Stimulation
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Raynaud Phenomenon, Primary Raynaud Phenomenon
Potential Benefit for Non Invasive Vagus Nerve Stimulation Using GammaCore in the Treatment of Raynaud's Phenomena.
Raynaud's phenomenon (RP) is a common vascular disorder that affects approximately 10% of the general population. RP is associated with significant morbidity that may include loss of the digits due to repeated episodes of…
- Conditions
- Raynaud Phenomenon, Primary Raynaud Phenomenon, Raynaud Disease, Raynaud Syndrome
- Trial name
- NCT03869008
- Testing
- gammaCore Sapphire
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Toledo Health Science Campus
Bruxism
Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation in Bruxism
Our study aimed to investigate the effects of transcutaneous auricular vagus nerve stimulation (TAVNS) application on treatment efficacy in bruxism in terms of masseter muscle activity, pain, stress level, sleep and life quality…
- Trial name
- NCT06386809
- Testing
- TAVNS, Exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bandırma Onyedi Eylül University
Post Herpetic Neuralgia (PHN)
Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia
The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) in the treatment of patients with post-herpetic neuralgia (PHN).
- Trial name
- NCT07123987
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS), traditional medical treatment for PHN
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mohamed Hosny Ismail Easa
Knee Osteoarthritis
taVNS in Veterans With Knee OA (AVAHCS)
The objectives of this study are to identify an optimal transcutaneous auricular vagus nerve stimulation (taVNS) dosing regimen for pain relief and anti-inflammatory effects in Veterans with knee osteoarthritis (OA), compared to…
- Trial name
- taVNS (NCT07804199)
- Testing
- Methylprednisolone acetate, taVNS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Fibromyalgia Syndrome
Effects of Left and Bilateral Transcutaneous Auricular Vagus Nerve Stimulation on Pain, Mood, and Autonomic Function in Female Fibromyalgia Patients
This study aimed to examine the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on pain, depression, anxiety, functionality, and autonomic function in fibromyalgia syndrome (FMS).
- Trial name
- NCT06871306
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Esophageal Diseases
The Effect of Transcutaneous Vagal Nerve Stimulation on Reducing Oesophageal Pain Hypersensitivity
We are evaluating the role of transcutaneous electrical vagal nerve stimulation in the prevention of oesophageal pain hypersensitivity using a validated human model in healthy volunteers.
- Trial name
- NCT02620176
- Testing
- Transcutaneous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wingate Institute of Neurogastroenterology
Gastro Esophageal Reflux
The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity
Reflux hypersensitivity is the disease that causes chest pain, heartburn and regurgitation and can impair patients' quality of life.
- Trial name
- NCT04253444
- Testing
- slow deep breathing
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen Mary University of London
Central Auditory Disease, Auditory Processing Disorder, Central
taVNS Effect on Central Auditory Processing
The behavioral effects of vagus nerve stimulation (VNS) and observed activation in the auditory cortex with transcutaneous auricular VNS (taVNS) raise questions about their potential impact on auditory processing.
- Conditions
- Central Auditory Disease, Auditory Processing Disorder, Central, Auditory Processing Disorders, Vagus Nerve Stimulation
- Trial name
- NCT06970444
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medipol University
Vagus Nerve Stimulation
How Does Vagus Nerve Stimulation Affect Blood Glucose, Food, and Movement Cravings?
The purpose of this study is to determine the feasibility of using non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) to examine physiological and psychological responses in a college-aged healthy population
- Trial name
- NCT07457372
- Testing
- Active taVNS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Borderline Personality Disorder
Transcutaneous Vagus Nerve Stimulation (tVNS) for Borderline Personality Disorder (tVNS-BPD)
The goal of this clinical trial is to test the efficacy of transcutaneous vagus nerve stimulation (tVNS) in borderline personality disorder.
- Trial name
- tVNS-BPD (NCT05892900)
- Testing
- Transcutaneous vagus nerve stimulation (tVNS)
- Where
- Sweden
- Volunteers
- 42 people
- Sponsor
- Sahlgrenska University Hospital
Tourette Syndrome, Chronic Tic Disorder
Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Tic Disorders/Tourette's Syndrome in Children and Adolescents
The objective of this trial is to evaluate the effect of transcutaneous auricular vagus nerve stimulation compared to sham stimulation in improving chronic tic disorder or Tourette's syndrome in children and adolescents.
- Trial name
- NCT07854665
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 124 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Chronic Tension-Type Headache, Episodic Tension-Type Headache
Treatment of Tension Headache Using Soft Tissue Techniques VS Vagus Stimulation Techniques.
A treatment based on manual therapy and vagus nerve stimulation is more effective than manual therapy only to reduce frequency, intensity and pressure pain threshold in patients with tension type headache.
- Trial name
- NCT05097300
- Testing
- Suboccipital inhibition, Ischemic pressure, Passive stretching
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Lucia Trullenque Espallargas
Long COVID, Vagus Nerve Stimulations
Vagus Nerve Stimulation for Post-COVID Syndrome
The aim of this study is to increase parasympathetic activity and decrease the severity of symptoms by providing vagal stimulation with the t-VNS method in order to suppress the increased sympathetic activity in patients with…
- Conditions
- Long COVID, Vagus Nerve Stimulations, Heart Rates, Autonomic Nervous System Disorders
- Trial name
- NCT05679505
- Testing
- Auricular transcutaneous vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University