Clinical trials: Vaginal Dryness
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Vaginal Disease
Open Non-Comparative Clinical Trial Study To Evaluate The Performance And Safety Of Ainara®
This study evaluates treatment with the medical device Ainara on the improvement of vaginal dryness evaluated by Vaginal Health Index (VHI) and Visual Analog Scale (VAS) in comparison with the baseline condition.
- Trial name
- NCT04245358
- Testing
- Ainara
- Where
- Romania
- Volunteers
- 50 people
- Sponsor
- Italfarmaco
Genitourinary Abnormality, Breast Cancer Female
GSM (Genitourinary Syndrome Of Menopause) Management In Breast Cancer Survivors
The impact of treatment for GSM on the quality of life will be examined for postmenopausal women (defined as last menstrual period > 1 year ago or 6 months ago with FSH >40) who have been diagnosed with breast cancer.
- Conditions
- Genitourinary Abnormality, Breast Cancer Female, Vaginal Abnormality, Urinary Tract Infections
- Trial name
- GSM (NCT03185169)
- Testing
- Replens and coconut oil
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Alta Bates Summit Medical Center
Dyspareunia, Menopause
Genital Laser Treatment in Postmenopausal Patients
Regulation of sexual functions without hormonal support in order to correct the sexual dysfunctions in women with the estrogen hormone lost in the menopausal process.
- Conditions
- Dyspareunia, Menopause, Sexual Activity, Atrophy Vulva
- Trial name
- NCT05631665
- Testing
- Survey results before and after laser treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Vaginismus, Vaginal Atrophy
Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal Women
Hyaluronic Acid is indicated for the relief of vaginal dryness, itching, and irritation, or the reduction of vaginal lubrication with prolonged hydration effects for up to 72 hours.
- Conditions
- Vaginismus, Vaginal Atrophy, Menopause
- Trial name
- NCT06564883
- Testing
- 0.20% sodium hyaluronate gel
- Volunteers
- 45 people
- Sponsor
- Biolab Sanus Farmaceutica
Breast Cancer, Vaginal Dryness
Breast Cancer, Aromatase Inhibitor Therapy, and Sexual Functioning: The Effects of Vaginal Testosterone Therapy
It is well documented that women who have breast cancer may experience a decrease in quality of life and sexual functioning due to side effects from adjuvant endocrine therapy, typically aromatase inhibitors (AIs).
- Conditions
- Breast Cancer, Vaginal Dryness, Dyspareunia, Sexual Health Quality of Life
- Trial name
- NCT01697345
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Creighton University
Vaginal Personal Care
Randomized, Double-Blind Placebo-Controlled Trial to Assess Overall User Experience of a Synbiotic Vaginal Suppository
The purpose of this study is to assess the impact of a personal care product on vaginal health in individuals with a self-reported history of vaginal discomforts such as malodor, bothersome discharge, itching, irritation, and…
- Trial name
- NCT06236893
- Testing
- VH-01 vaginal suppository tablet
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seed Health
Vaginal Dryness, Breast Cancer
Efficacy and Safety of Vaginal Radiofrequency for Vulvovaginal Atrophy in Breast Cancer Patients
This Phase III, randomized, balanced, parallel-group, multicenter trial aims to evaluate the effect of vaginal radiofrequency on symptoms of vaginal dryness at six months.
- Conditions
- Vaginal Dryness, Breast Cancer, Vulvovaginal Atrophy
- Trial name
- RF-Vaginale (NCT06900374)
- Testing
- GynWave-360, Local hydratation
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Oscar Lambret
Vaginal Dryness, Menopausal Women
Evaluation of Viscosity of a Vaginal Moisturizer
To evaluate the perception of viscosity of a vaginal moisturizer in postmenopausal women
- Trial name
- NCT03782961
- Testing
- sodium lactate and combination of polymers
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Farmoquimica S.A.
Vulvovaginal Atrophy
Vaginal Microbiota Among Postmenopausal Women
It is known that vaginal bacteria have an impact upon the health status of the host, in some cases protecting against infection and in other cases causing infection, depending on the bacterial types present.
- Trial name
- NCT01084616
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Cancer
Study of Sexual Quality of Life in Women With Breast Cancer Who Had Multidisciplinary Management With Photobiomodulation for Genitourinary Syndrome of the Menopause
The treatment of breast cancer as well as the disease are responsible for genito-urinary symptoms that can persist over time and impair quality of life.
- Trial name
- EVABIOSEIN (NCT06347926)
- Testing
- Questionnaires given before and after photobiomodulation
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Sexual Dysfunction, Physiological
Vaginal Testosterone Cream vs ESTRING for Vaginal Dryness or Decreased Libido in Early Stage Breast Cancer Patients
The purpose of this clinical research study is to determine whether the ESTRING or a special preparation of a testosterone cream inserted vaginally are safe for use in breast cancer patients.
- Trial name
- E-String (NCT00698035)
- Testing
- Testosterone Cream, Estring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of California, San Francisco
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
Pilot Study of Individualized Treatment for Genitourinary Syndrome of Menopause in Women After Cancer Treatment
This pilot study is designed to evaluate an individualized approach to the treatment of genitourinary syndrome of menopause (GSM) in women who have undergone oncological treatment.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Menopause, Female Cancer Survivors
- Trial name
- NCT07420647
- Testing
- Non-ablative vaginal Er:YAG laser therapy, Standard care
- Where
- Slovenia
- Volunteers
- 65 people
- Sponsor
- Institute of Oncology Ljubljana
Vaginal Dryness
Evaluation of the Efficacy and Safety of Mucogye® Gel as a Moisturizer
The aim of this post-Market Clinical Follow-up (PMCF) study for a class IIb medical device is to confirm th efficacy and safety of Mucogyne Gel as a moisturizer in women with vaginal dryness irrespective of the cause; when used…
- Trial name
- HYDRAGYNE (NCT05913479)
- Testing
- Mucogyne Gel
- Where
- 4 sites in France
- Volunteers
- 34 people
- Sponsor
- Biocodex
Menopause Related Conditions, Postmenopausal Symptoms
Use of J3 Bioscience Lubricating Intravaginal Ring VR101 to Relieve the Symptoms of Vaginal Dryness
This investigation is designed to demonstrate the safety and efficacy of the VR101 lubricating intravaginal ring (IVR) in treating the symptoms of vaginal dryness.
- Trial name
- NCT03150407
- Testing
- VR101 Device (Efficacy), VR101 Device (Safety)
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- J3 Bioscience, Inc.
Vulvodynia, Dyspareunia
Therapy to Prevent Sexual Pain in Breast Cancer Survivors
The purpose of this protocol is to determine whether pain with sexual intercourse can be reduced in menopausal, breast cancer survivors and to evaluate the effectiveness of a non-hormonal therapy (Lidocaine Liquid) vs.
- Conditions
- Vulvodynia, Dyspareunia, Breast Cancer, Menopause
- Trial name
- NCT01539317
- Testing
- Topical liquid lidocaine, Topical saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OHSU Knight Cancer Institute
Atrophic Vaginitis
A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis
The purpose of this study is to determine the therapeutic equivalence of Mylan's estradiol vaginal cream to Estrace® cream and superiority of both products to placebo.
- Trial name
- NCT02195986
- Testing
- Estradiol Vaginal Cream, 0.01%, Estrace® 0.01% cream
- Where
- 21 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Vaginal Atrophy, Sexual Dysfunction
Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause
This multi-center clinical trial will evaluate the safety and long-term efficacy of hybrid fractional 2940 nm and 1470 nm lasers for treatment of symptoms of Genitourinary Syndrome of Menopause.
- Conditions
- Vaginal Atrophy, Sexual Dysfunction, Dyspareunia, Vaginal Dryness
- Trial name
- NCT03178825
- Testing
- Hybrid Fractional Laser
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sciton
Genitourinary Syndrome of Menopause (GSM), Breast Cancer
Efficacy of Non-ablative Radiofrequency Combined With Pelvic Floor Muscle Training for Genitourinary Syndrome of Menopause in Breast Cancer Survivors (RF-SGM)
The goal of this clinical trial is to find out whether non-ablative radiofrequency (RF) applied together with pelvic-floor muscle exercises can ease vaginal dryness and other symptoms of genitourinary syndrome of menopause (GSM)…
- Trial name
- NCT07034976
- Testing
- Active Radiofrequency (Capenergy C500 UpGradeC200)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Menopause, Dyspareunia
Multi-point Intra-mucosal Injections of Cross-linked Hyaluronic Acid (DESIRIAL®) in the Vaginal Vestibule
The main objective of this study is to measure changes in the thickness of the vaginal lining (epithelium + underlying stroma) between 0 and 8 weeks after injection.
- Trial name
- INREG 1 (NCT02739880)
- Testing
- DESIRIAL® (Intra-mucosal Injections of Cross-linked Hyaluronic Acid)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes