Clinical trials: Vaginal Hysterectomy
Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy
Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV
The purpose of this study is to compare the vaginal sacrospinous colpopexy and high uterosacral colpopexy in the treatment of genital prolapse grade III/IV in women with uterus.
- Conditions
- Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Complete Tear, Sacrospinous Ligament, Uterosacral Ligament; Rupture
- Trial name
- NCT01347021
- Testing
- sacrospinous colpopexy versus high uterosacral colpopexy
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Gynecologic Surgical Procedures
Barbed vs Standard Suture for Laparoscopic Vaginal Cuff Closure
Total laparoscopic hysterectomy is a procedure that is performed each time more often. One of the problems described for this procedure has to do with the closure of the vaginal vault, increased surgical time when suture…
- Trial name
- NCT03038945
- Testing
- 2/0 barbed suture, 0/0 Vicryl suture
- Where
- Colombia
- Volunteers
- 150 people
- Sponsor
- CES University
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Laparoscopic Hysterectomy for Benign Conditions
Comparing Two Devices of Uterine Manipulation and Vaginal Fornix Delineation at Total Laparoscopic Hysterectomy
We hypothesize, that the use of the Hohl manipulator® at total laparoscopic hysterectomy reduces operative time (from skin incision to detachment of the uterus) and lateral termal damage of the vaginal wall during colpotomy due…
- Trial name
- NCT02197728
- Testing
- Use of the Colpo-Probe™ Vaginal Fornix Delineator or Hohl manipulator® during total laparoscopic hysterectomy
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Unity Health Toronto
Minimally Invasive Hysterectomy in Large Uteri
Vaginal Hysterectomy Versus Laparoscopically Assisted Vaginal Hysterectomy for Large Uteri
The investigators compare between Vaginal Hysterectomy and Laparoscopically assisted vaginal hysterectomy in cases of large uteri weighing more than 280 gm regarding operative and Postoperative outcomes
- Trial name
- NCT02826304
- Testing
- Vaginal hysterectomy, Laparoscopic assisted vaginal hysterectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams Maternity Hospital
Cervical Cancer, Endometrial Cancer
Pelvic Drains After Radical Hysterectomy in Treating Patients With Uterine, Cervical, or Vaginal Cancer
RATIONALE: The use of pelvic drains may help to prevent complications following radical hysterectomy and pelvic lymphadenectomy.
- Conditions
- Cervical Cancer, Endometrial Cancer, Infection, Perioperative/Postoperative Complications
- Trial name
- NCT00003267
- Testing
- infection prophylaxis and management, management of therapy complications, surgical procedure
- Where
- 18 sites in Austria, Belgium and 6 more
- Volunteers
- 214 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Blood Loss
Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss
Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation
- Trial name
- NCT04760301
- Testing
- local tranexamic acid injection, local normal saline injection to cervix
- Where
- 2 sites in Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Myoma, Adenomyosis
To Compare to 2-channel and Multiple-channel Single Port Laparoscopic-assisted Vaginal Hysterectomy
The main objective of this trial is to assess the efficacy and safety of single port-access laparoscopic-assisted vaginal hysterectomy.
- Trial name
- NCT01564602
- Testing
- comparison multiple channel port laparoscopic surgery
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
POPQ Associated With Total Laparoscopic Hysterectomy
The goal of this observational study is to evaluate the impact of different hysterectomy (removal of the uterus) techniques on the risk of pelvic organ prolapse (situation when one or more of your pelvic organs like your bladder…
- Conditions
- Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle, Endometrial Hyperplasia, Pelvic Organ Prolapse (POP)
- Trial name
- POP-LAP (NCT07137299)
- Testing
- Questionnaire and Physical Exam
- Where
- 4 sites in Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Silesia
Abdominal Hysterectomy
The Application of Vaginal Manipulator in Abdominal Hysterectomy Operations
If a vaginal manipulator is used for abdominal hysterectomy, the vagina can be cut and separated from the cervix without cutting the Cardinal and Sacrouterine ligaments and protecting the top of the vaginal tissue (Portio…
- Trial name
- NCT05420662
- Testing
- Manipulation of vagina during abdominal hysterectomy operation, Classical conventional abdominal hysterectomy operation
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Kocaeli University
Fibroids
Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes
In this study the investigators will perform a randomized trial to compare the surgical outcomes of vaginal versus abdominal morcellation of the uterus during hysterectomy.
- Trial name
- NCT02703246
- Testing
- abdominal morcellation, vaginal morcellation
- Where
- United States
- Sponsor
- George Washington University
Physical Activity, Surgery
Study Investigating Role of Unalike Patient Positioning on PROMIS Scores
The primary objective is to assess the impact of patient positioning using the candy cane stirrups as compared to boot stirrups on physical functioning outcomes at 6 weeks post-op
- Conditions
- Physical Activity, Surgery, Vaginal Hysterectomy, Vaginal Surgery
- Trial name
- STIRUPPS (NCT03446950)
- Testing
- Vaginal Surgery
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Uterine Myomatosis, Laparoscopy
Efficacy of In-bag Morcellation
Laparoscopic mini-invasive surgery supplanted laparotomy for many years, including hysterectomy or myomectomy (less postoperative complications compared to laparotomy) However the US Federal Drug Administration (FDA) strongly…
- Conditions
- Uterine Myomatosis, Laparoscopy, Hysterectomy, Vaginal
- Trial name
- FIBROSAC (NCT03281460)
- Testing
- laparoscopic myomectomy or hysterectomy with More-cell-Safe AMI bag morcellation, laparoscopic myomectomy or hysterectomy without any morcellation bag
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Hospices Civils de Lyon
Vaginal Hysterectomy, Pelvic Organ Prolapse Vaginal Surgery
The Effect of Physiotherapy Treatment Following Gynaecological Surgery
Optimal pelvic floor muscle function is known to assist bladder and bowel function and control, pelvic organ support, as well as other areas of health.
- Trial name
- NCT00222326
- Testing
- Pelvic floor muscle training and lifestyle modification
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Vaginal Cuff Dehiscence, Vaginal Hematoma
Laparoscopic Versus Transvaginal Cuff Closure
It is still debatable whether that the transvaginal approach to vault closure or laparoscopic suturing are associated with lower risks of vaginal cuff complications .
- Conditions
- Vaginal Cuff Dehiscence, Vaginal Hematoma, Vaginal Infection
- Trial name
- NCT03898726
- Testing
- laparoscopical l cuff closure
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- El-Galaa Military Medical Complex
Pain
0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy
This study aims to compare the effect of spinal morphine between the dose 0.05 mg and 0.1 mg on the amount of morphine during the first 24 hours postoperative.
- Trial name
- NCT01080911
- Testing
- Morphine
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Uterine Diseases
Laparoscopic Versus Vaginal Cuff Closure During LH in Benign Gynecological Lesions
To compare vaginal cuff closure via Bakay purse string with vaginal cuff closure via vaginal route with continuous locked suturing after total laparoscopic hysterectomy for benign lesions.
- Trial name
- NCT05823935
- Testing
- Bakay purse string, Cuff closure via vaginal route group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Vaginal Hysterectomy, Postoperative Pain
Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Hysterectomy Via Vaginal Route
Hysterectomy performed through the vaginal route (HVR) is the preferred method for women seeking hysterectomy to address uterine concerns such as premalignant conditions and fibroids.
- Conditions
- Vaginal Hysterectomy, Postoperative Pain, vNOTES
- Trial name
- NCT06429605
- Testing
- duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Postoperative Pain
Vaginal Wound Infiltration Analgesia for Postoperative Pain After Laparoscopic Hysterectomy: a Randomized Trial
In cases of laparoscopic hysterectomy , women were randomized to two groups: ropivacaine ( vaginal wound infiltration analgesia) vs. control group. Results regarding postoperative pain and need of oxycodone.
- Trial name
- NCT02767544
- Testing
- Vaginal wound local analgesia after laparoscopic hysterectomy
- Volunteers
- 81 people
- Sponsor
- Helsinki University Central Hospital
Uterine Bleeding
Laparoscopic Versus Vaginal Hysterectomy in Women With Abnormal Uterine Bleeding Using Bipolar Vessel Sealer
This study will be a randomized clinical trial to evaluate the surgical performance and outcome of total laparoscopic hysterectomy compared to non-descent vaginal hysterectomy ,using bipolar vessel sealer,in cases of abnormal…
- Trial name
- NCT04237558
- Testing
- Vaginal hysterectomy, Laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University