Clinical trials: Vaginal Infection
Vulvovaginal Candidiasis (VVC), Yeast Vaginitis
Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)
The objective of this study is to determine clinical cure rate and safety of a proprietary Vaginal Cooling Device (VCD) in women with VCC.
- Trial name
- NCT06983041
- Testing
- vaginal cooling device
- Where
- 10 sites in United States
- Volunteers
- 55 people
- Sponsor
- Coologics, Inc
Bacterial Vaginosis
Dietary Supplementation of Lactogyn in Women With Bacterial Vaginosis
The objective of the study is to determine clinical efficacy of Lactogyn (Lactobacillus Crispatus, L. brevis, L.acidophilus) in prevention of recurrent BV
- Trial name
- NCT03601429
- Testing
- Lactogyn
- Where
- Ukraine
- Volunteers
- 166 people
- Sponsor
- Vesale Pharmaceutica
Infection Control / Methods, Surgical Site Infection (SSI)
Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.
- Trial name
- SSI (NCT07474194)
- Testing
- Clindamycin vaginal cream, Vaginal preparation with povidone- iodide solution 10 %
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Chorioamnionitis, Intrauterine Infection
Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term
This prospective randomized controlled study examines whether the type of glove used (sterile vs clean) for cervical examination to assess progression in labor impacts the rates of intrapartum and/or postpartum infection in…
- Conditions
- Chorioamnionitis, Intrauterine Infection, Postpartum Endometritis, Puerperal Infection
- Trial name
- NCT05603624
- Testing
- Cervical examination to assess labor
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Vaginal Infection
Epidemiology of Abnormal Vaginal Discharge During Pregnancy
Vaginitis among women of childbearing age is well acknowledged as a public health concern due to its high occurrence. Vulvovaginitis is a disorder of the vulva and/or vagina caused by infection, inflammation, or changes in the…
- Trial name
- NCT04719754
- Testing
- Vaginal swab
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Vulvovaginal Candidiasis
Safety and Efficacy of Oral Ibrexafungerp (SCY-078) vs. Oral Fluconazole in Subjects With Vulvovaginal Candidiasis
This is a randomized, multicenter, evaluator blinded study to evaluate the safety, tolerability, efficacy and pharmacokinetics of SCY-078 compared to Fluconazole in adult patients with moderate to severe Vulvovaginal Candidiasis…
- Trial name
- NCT02679456
- Testing
- SCY-078, Fluconazole
- Where
- 2 sites in Dominican Republic
- Volunteers
- 96 people
- Sponsor
- Scynexis, Inc.
HIV Infections
Botswana Study of UC-781 Vaginal Microbicide
This study will test the safety, side effects, and acceptability of two strengths of UC-781 gel when used by women and men in Botswana for two weeks.
- Trial name
- NCT00385554
- Testing
- UC-781 carbomer gel, 0.1% and 0.25%
- Where
- 3 sites in United States, Botswana
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Vaginal Candidiasis, Bacterial Vaginosis
Observational Program Neo-Penotran® Forte
Vaginitis is the most common gynecologic diagnosis in the primary care setting. In approximately 90 percent of affected women, this condition occurs secondary to bacterial vaginosis, vulvovaginal candidiasis, trichomoniasis or…
- Conditions
- Vaginal Candidiasis, Bacterial Vaginosis, Trichomonal Vaginitis
- Trial name
- NCT01335373
- Testing
- Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
- Where
- Kazakhstan
- Volunteers
- 13,024 people
- Sponsor
- Bayer
Preventative Laparoscopic Hysterectomy
Chlorhexidine vs Povidone Iodine Vaginal Prep in Decreasing Postoperative Infection in Total Laparoscopic Hysterectomy
This is a randomized control trial which will randomize patients who will be undergoing laparoscopic (conventional or robotic assisted) total hysterectomy to vaginal prep with 4% chlorhexidine gluconate vs 10% povidone iodine.
- Trial name
- NCT05692986
- Testing
- A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Vaginitis
Effects of LiveSpo X-SECRET in SupportiveTreatment of Vaginitis
Vaginitis is a common reproductive infection in women worldwide, particularly in tropical and underdeveloped countries. Traditional antibiotic treatments can disrupt the balance of beneficial bacteria, requiring repeated use…
- Trial name
- NCT06165354
- Testing
- 0.9% NaCl physiological saline, LiveSpo X-secret
- Where
- 2 sites in Vietnam
- Volunteers
- 120 people
- Sponsor
- Anabio R&D
Candidiasis, Vulvovaginal, Candidiasis of Vagina
Non-ablative Er:YAG for Recurrent Candidiasis
The objective of the study wa to assess the safety, acceptability and effectiveness of non-ablative Er:YAG laser therapy for treatment of symptoms and microbiological conditions of women with recurrent vulvovaginal candidiasis…
- Conditions
- Candidiasis, Vulvovaginal, Candidiasis of Vagina, Candidiasis, Genital, Recurrent Candidiasis of Vagina
- Trial name
- NCT06572488
- Testing
- Non-ablative SMOOTH mode Er:YAG laser
- Where
- Argentina
- Volunteers
- 167 people
- Sponsor
- Espacio Gaspar Clinic
Vaginitis
VS-Sense Result Reading Clarity
This study is designed to demonstrate the result reading clarity of the VS-SENSE is substantially equivalent to the result reading clarity of the Nitrazine pH Paper test for vaginal secretions.
- Trial name
- NCT00803127
- Testing
- vs-sense
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Vaginosis, Bacterial
Diagnosing Bacterial Vaginosis/Vaginitis (BV) Using the Gynecologene Test Method
This study is designed as a prospective evaluation of the diagnostic performance of the multiplex nucleic acid-based genetic test (Gynecologene Next-Generation Sequencing test) to identify known significant causative organisms in…
- Trial name
- SAGE (NCT02558179)
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- American International Biotechnology