Clinical trials: Validation
Gonarthrosis
Validation of a Knee Brace for Gonarthrosis
A study about the effects of different fastening systems for knee braces on comfort, ease of installation and treatment efficacy both physical and psychological.
- Trial name
- NCT05814471
- Testing
- Cable fastening system and 3d printed straps(14 days), Velcro straps system(14 days), Adjustment period(Velcro-14 days)
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- TOPMED
Fever
SCT02 Clinical Accuracy Validation
The aim of the study is to validate the accuracy of the temporal thermometer of Withings SCT02
- Trial name
- WIBOFE (NCT06637878)
- Testing
- Investigational Device (Withings SCT02) temporal thermometer measurement, Reference Device (Withings SCT01) temperature measurement
- Where
- 5 sites in United States
- Volunteers
- 118 people
- Sponsor
- Withings
Gastroenteritis
Serologic Assay Validation and Proficiency Testing of HIL-214 in Adults
The purpose of this trial is to obtain serum for proficiency testing to confirm assay validity is maintained following the dosing of adults with a pediatric dose of HIL-214.
- Trial name
- NCT05972733
- Testing
- HIL-214
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HilleVax
Healthy
Validation Study of Mean Arterial Pressure (MAP) Parameter of Masimo INVSENSOR00073
The aim of the study is to validate the Mean Arterial Pressure (MAP) parameter of Masimo INVSENSOR00073 against the gold standard blood pressure measurements from the arterial line while subject undergo a blood pressure variation…
- Trial name
- NCT06334055
- Testing
- Masimo INVSENSOR00073
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Fluid Retention Tissue
Measuring Thoracic Impedance in Hemodialysis Patients With the u-Cor Monitoring System
The purpose of this study is to measure the fluid changes in the body using a device called the µ-Cor System, an investigational device.
- Trial name
- MaTcH (NCT03072732)
- Testing
- u-Cor System, ZOE Fluid Status Monitor
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Zoll Medical Corporation
Healthy
Oxygen Reserve Index (ORi) Expanded Data Set Validation of INVSENSOR00025
ORi is a unitless index that could help clinicians with their assessments or normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT04079816
- Testing
- INVSENSOR00025
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
COVID-19
Validation of a Rapid Quantitative Test for Loss of Smell in COVID-19 Subjects
The purpose of this study is to evaluate the performance of a non-invasive olfactory device as a rapid indicator of COVID-19 in positive subjects.
- Trial name
- NCT04431908
- Testing
- olfactory device
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- Yale University
Cancer
Development and Validation of a Tumour Oxygenation Monitoring Probe
Laboratory based study in which novel tissue oxygenation probe with the potential provide novel means for assessing response to cancer treatment will be developed and validated.
- Trial name
- NCT03982355
- Testing
- DRS probe
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Sleep Apnea
A Validation Study of the NightOwl PAT-based Home Sleep Apnea Test
The objective of this study is to evaluate the performance of a miniaturized sleep apnea test, called NightOwl. The system consists of a sensor placed on the fingertip and a cloud-based analytics software.
- Trial name
- NCT04191668
- Testing
- NightOwl
- Where
- 3 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ectosense NV
Sleep-Disordered Breathing, Sleep Architecture
Belun Ring Platform With an Improved Algorithm for OSA Assessment
OSA is commonly diagnosed with either attended in-lab polysomnography (PSG) or unattended home sleep apnea testing (HSAT). The BLS-100 (Belun Technology Company Limited, Hong Kong) is a novel neural network-based HSAT platform…
- Trial name
- NCT04885062
- Testing
- Belun Ring, PSG
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Belun Technology Company Limited
Sleep Apnea, Obstructive, Sleep Apnea, Central
DreamKit Respiratory Effort Signal Validation
This study has been developed in order to demonstrate the validity of the DreamKit respiratory effort signal.
- Trial name
- NCT04926077
- Testing
- DreamKit
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Oxygen Deficiency
Validation of Next Generation Cerebral and Tissue Oximeter
This is a validation study of a near-infrared spectroscopy (NIRS) device designed to measure the cerebral tissue oxygen saturation.
- Trial name
- NCT03128372
- Testing
- Desaturation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Gonococcal Infection
Clinical Validation of a Molecular Test for Ciprofloxacin-Susceptibility in Neisseria Gonorrhoeae
This study is a multi-center, single-arm, open-label clinical study to assess the efficacy of one dose of ciprofloxacin given orally in subjects infected with untreated gyrase A (gyrA) serine 91 genotype Neisseria gonorrhoeae (N.
- Trial name
- NCT02961751
- Testing
- Ciprofloxacin
- Where
- 9 sites in United States
- Volunteers
- 211 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Well-being
Develop and Validation of Measurement-Based Transition Assistance
Although some Veterans seek help when they experience post-military readjustment challenges, many do not. One factor that stands in the way of Veterans' willingness to seek help for these challenges is their lack of knowledge…
- Trial name
- MBTA (NCT05384171)
- Testing
- Measurement-Based Transition Assistance (MBTA)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Inflammatory Bowel Disease, Perianal Fistula
Perianal Fistula (PAF) Validation and Burden of Illness Study
The purpose of this study is to gain a better understanding of the disease burden and unmet need of perianal fistulas within Crohn's disease (CD) in Ontario.
- Conditions
- Inflammatory Bowel Disease, Perianal Fistula, Crohns Disease
- Trial name
- NCT03981939
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 3,032 people
- Sponsor
- Takeda
Brain Injuries, Traumatic
INTRuST Structured Assessment For Evaluation of TBI (SAFE-TBI)
The current study will evaluate the initial reliability and validity of a new instrument, the INTRuST Structured Assessment for Evaluation of TBI (SAFE-TBI), in three samples of Operation Enduring Freedom/Operation Iraqi…
- Trial name
- SAFE-TBI (NCT01554891)
- Where
- 6 sites in United States
- Volunteers
- 305 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Sleep Apnea, Obstructive
Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea
The purpose of this study is to evaluate the sensitivity and specificity of the Belun Ring Pulse Oximetry system for screening of obstructive sleep apnea (OSA) in adults during standard polysomnography sleep study conditions.
- Trial name
- NCT04121923
- Testing
- Belun Ring Pulse Oximeter
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Belun Technology Company Limited
Liver Disease
Prospective Validation of a Plasma Transfusion Dosing Algorithm in Patients With Chronic Liver Disease
This study plans to learn more about transfusion of a human blood component called plasma in patients who have liver problems. Patients are asked to be in this study because they have liver disease and therefore may require the…
- Trial name
- NCT02366845
- Testing
- Fresh Frozen Plasma, Pre-Transfusion International Normalized Ratio (INR), Post-Transfusion International Normalized Ratio (INR)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Asthma, COPD
Protein Biomarker Discovery and Validation in Chronic Obstructive Pulmonary Disease (COPD) And Asthma
The purpose of the study is to better understand proteomics of asthma and COPD, and response to therapy. There are two Phases to this study broken into two arms.
- Trial name
- Proteomics (NCT02487394)
- Testing
- Exhaled Breath Condensate (EBC)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Medical Branch, Galveston