Clinical trials: Validation Studies, open to volunteers
Psychological Well Being
Test-Retest Reliability of the WB6Dim Digital Well-Being Tool: A 3-Day Interval Study
This study aims to establish the test-retest reliability of the WB6Dim digital self-assessment tool across its eight well-being dimensions, using a 3-day interval protocol designed to minimize the probability of genuine…
- Trial name
- WB6Dim-TRT (NCT07433764)
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Clover Link
Nasopharyngeal Neoplasms, Laryngeal Disease
AI System for Anatomic Recognition & Lesion Detection in Nasopharyngolaryngoscopy: A Prospective Study
An artificial intelligence-assisted system is trained and validated by collecting nasopharyngolaryngoscopy images from patients.
- Trial name
- NCT07326358
- Testing
- Diagnostic
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Chronic Obstructive Pulmonary Disease
CLEAR Model for Predicting Ventilatory Liberation in Severe COPD
This prospective observational cohort study aims to prospectively evaluate and validate the Clinical Load, Exchange, Ability of Respiration, and Reserve (CLEAR) model for predicting sustained ventilatory liberation in patients…
- Trial name
- CLEAR (NCT07579052)
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Postoperative Complications, Thoracic Surgery
Wearable Device-Based Early Warning of Postoperative Complications in Thoracic Surgery
After thoracic surgery, some patients may develop complications such as lung infection, abnormal heart rhythm, fluid around the lung, prolonged air leak, wound infection, emergency department visits, or hospital readmission.
- Conditions
- Postoperative Complications, Thoracic Surgery, Perioperative Monitoring
- Trial name
- wearable (NCT07646730)
- Testing
- Wearable device-based perioperative monitoring
- Where
- China
- Volunteers
- 650 people
- Sponsor
- Tongji Hospital
Lipedema
Validity and Reliability of the 2-Minute Step Test in Patients With Lipedema
Lipedema is a chronic, progressive adipose tissue disorder that predominantly affects women and is characterized by symmetric, disproportionate subcutaneous fat accumulation in the lower extremities, pain, tenderness, and easy…
- Trial name
- NCT07752017
- Volunteers
- 55 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Type II Endoleak, Abdominal Aortic Aneurysm Enlargement
Deep-learning Predictors of Abdominal Aortic Aneurysm Enlargement in Type II Endoleaks After Endovascular Aortic Repair: The RADAR Study
Background and rationale: Abdominal aortic aneurysm (AAA) is a weakening and enlargement of the main artery in the abdomen. Endovascular aneurysm repair (EVAR) is a minimally invasive treatment used to repair an AAA.
- Trial name
- RADAR (NCT07783126)
- Testing
- Artificial intelligence model analyzing preoperative CT angiography
- Volunteers
- 1,250 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Giant Cell Arteritis (GCA)
The VGR GCA Cohort: Ultrasound, Biopsy and Biomarkers - Novel Methods for Diagnosis, Monitoring and Prognosis in Giant Cell Arteritis.
Giant cell arteritis (GCA) is the most common vasculitis in the elderly and is usually treated with long-term corticosteroid therapy. Many patients experience relapses and treatment-related side effects.
- Trial name
- NCT07246577
- Where
- Sweden
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
PARKINSON DISEASE (Disorder)
Characterization and Validation of the Short Physical Performance Battery in Individuals Diagnosed With Parkinson's Disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with motor and non-motor impairments that affect physical function, mobility, balance, and quality of life.
- Trial name
- PDSPPB (NCT07780461)
- Where
- 2 sites in Spain
- Volunteers
- 350 people
- Sponsor
- University of Vigo
Healthy Nutrition, Healthy Diet
Baylor Infant and Toddler Biomarker of Nutrition Study
Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals.
- Trial name
- BITBONS (NCT05869760)
- Testing
- Carotenoid Intake, Serum carotenoid concentrations
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Prostate Cancer (Diagnosis)
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
This is a single center study evaluating whether a new blood test based on platelet proteins rather than plasma proteins can improve detection of prostate cancer and evaluate the degree of serious disease.
- Trial name
- NCT07144228
- Testing
- HeLP TM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Tuberculosis in HIV-infected Individuals, Drug Susceptible Pulmonary Tuberculosis
Short-Course Regimens for DS-PTB in AIDS Patients
This study adopts a multicenter, open-label, randomized controlled design, conducted across key designated AIDS diagnosis and treatment hospitals nationwide.
- Trial name
- NCT07608172
- Testing
- 2HPMZ/2HPM, 2HRZE/4HR
- Volunteers
- 148 people
- Sponsor
- Shanghai Public Health Clinical Center
Cognitive Intervention to Promote Healthy Development of Executive Function (EF) Skills in Young Children
Parent-Child EF Intervention
Koronis Biomedical Technologies Corporation (KBT) is developing a cognitive intervention to promote healthy development of Executive Function (EF) skills in young children by leveraging a smartphone-based training regime designed…
- Trial name
- NCT06924307
- Testing
- Executive Function Intervention
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Koronis Biomedical Technologies
Waldenstrom's Disease, Prognostic Index
Prognostic Analyses on a Validation Series of Patients With Waldenström's Disease
Waldenström's macroglobulinemia (WM) is defined by the association of bone marrow lymphoplasmocytic infiltration and monoclonal immunoglobulin M (IgM).
- Trial name
- SérieProWM (NCT05911802)
- Where
- 15 sites in France
- Volunteers
- 500 people
- Sponsor
- French Innovative Leukemia Organisation
Postoperative Recovery in Children
Thai Version of the Pediatric Quality of Recovery Score (PedSQoR): Translation and Psychometric Validation Study
Postoperative recovery in children is a complex, multidimensional process that differs substantially from recovery in adults, encompassing physical comfort, emotional well-being, behavioral changes, and psychosocial functioning.
- Trial name
- Thai-PedsQoR (NCT07378501)
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Adolescents and Young Adults With Cancer
A Study of Questionnaires in Adolescents and Young Adults With Cancer
The purpose of this study is to evaluate a questionnaire called PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults.
- Trial name
- NCT07212166
- Testing
- Patient-Reported Outcome Surveys, Spanish version of PRO-AYA and the cognitive interview
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Work-Related Musculoskeletal Disorders, Musculoskeletal Diseases
Development of Multidimensional Screening Tool for WMSDs
The purpose of this study is to develop a multidimensional screening tool for Work-Related Musculoskeletal Disorders (WMSDs) and to evaluate its psychometric properties.
- Conditions
- Work-Related Musculoskeletal Disorders, Musculoskeletal Diseases, Occupational Diseases
- Trial name
- NCT07367646
- Testing
- Survey Administration
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Sahmyook University
CHD - Congenital Heart Disease, Single Ventricle Heart Disease
PRecision Integrated Saturation Monitor
The purpose of this study is to find out if an abdominal pulse oximeter device is as accurate as a conventional fingertip pulse oximeter in pediatric patients.
- Trial name
- PRISM (NCT07686341)
- Testing
- vital sign monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Le Bonheur Children's Hospital
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Immune Thrombocytopenic Purpura, Coronary Artery Disease
Development and Prospective Validation of an AI Model for Prognosis in ITP Patients Undergoing Coronary Revascularization
This study employs a dual-cohort design to develop and validate a prognostic model for Major Adverse Cardiovascular Events (MACE) following revascularization in immune thrombocytopenia (ITP) patients with Coronary Artery Disease…
- Trial name
- ITP with CAD (NCT07426107)
- Volunteers
- 600 people
- Sponsor
- Xiao Hui Zhang
Multiple Sclerosis
Validation of the 18 kiloDalton Translocator Protein (TSPO) as a Novel Neuroimmunodulatory Target
In multiple sclerosis (MS) cells of the immune system attack the brain causing tissue damage. In secondary progressive MS (SPMS) these repeated immune attacks have stopped but despite this new damage continues to appear.
- Trial name
- TSPO (NCT03850301)
- Testing
- XBD173, Etifoxine
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Imperial College London