Clinical trials: Vaping Behavior
Vaping, Nicotine Absorption
Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants
This is a single-center, open-label, concentration-ranging study to evaluate the nicotine PK profile and PD effects in healthy adult experienced users of closed tank/cartridge e-cigarettes using four different variants of P4M3…
- Trial name
- NCT03379740
- Testing
- E-cigarette, P4M3-1.7%, P4M3-1.7%LA
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Vaping
Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
The aim of this study is to determine if graphic messages prevent future vaping use among African American and Latino adolescents.
- Trial name
- NCT04899999
- Testing
- Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Alcohol Use, E-cigarette Use
Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use
A high priority research area for the Food and Drug Administration Center for Tobacco Products (FDA CTP) is determining who will start using tobacco products and who will stop using tobacco products.
- Conditions
- Alcohol Use, E-cigarette Use, Cigarette Use
- Trial name
- NCT07010601
- Testing
- Experimental Tobacco Marketplace, Hypothetical Novel Nicotine Product Purchase Tasks
- Where
- United States
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Mark J Rzeszutek, PhD
Tobacco Use, E-Cigarette Use
E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease
This study is designed to enhance the understanding of the possible health effects of e-cigarette use by relating the acute and long-term use of e-cigarettes and conventional cigarettes ("products") to well-validated…
- Conditions
- Tobacco Use, E-Cigarette Use, Cardiovascular Diseases, Pulmonary Disease
- Trial name
- NCT03863509
- Testing
- Cigarettes, E-Cigarettes
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vaping, E-Cig Use
A Study of Cytisinicline for Vaping Cessation in Adult Smokers
This placebo-controlled Phase 2 study is being conducted at sites within the United States to evaluate the efficacy and safety profile of 3 mg cytisinicline administered TID for 12 weeks for vaping cessation.
- Trial name
- ORCA-V1 (NCT05431387)
- Testing
- cytisinicline, Behavioral support
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Achieve Life Sciences
Nicotine Vaping, Nicotine Dependence
Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency
Electronic nicotine delivery systems (ENDS) heat and vaporize a nicotine-containing liquid to produce an aerosol that can deliver nicotine to the blood and the brain.
- Conditions
- Nicotine Vaping, Nicotine Dependence, Nicotine Addiction
- Trial name
- NCT05430334
- Testing
- e-liquid 1, e-liquid 2, e-liquid 3
- Where
- Lebanon
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Mental and Behavioral Disorders, Withdrawal State
Effect of the Electronic Cigarette on Withdrawal Symptoms
Study rationale: Sensory/behavioural elements of smoking play a role in smoking behaviour and may have a potential to assist smoking cessation.
- Trial name
- ECIG24 (NCT01454362)
- Testing
- Nicotine
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
E-Cig Use, Vaping
A Virtual Reality Videogame for E-cigarette Prevention in Teens
The use of the Invite Only VR, with the aim to prevent the initiation of e-cigarette use in teens by increasing their knowledge, decreasing their intentions to use e-cigarettes, influencing their harm perceptions and attitudes…
- Trial name
- NCT04054765
- Testing
- videogame, treatment as usual
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Healthy
In-vivo Effects of E-cigarette Aerosol on Innate Lung Host Defense
While e-cigs are commonly represented as safer alternatives to tobacco cigarettes, little is known regarding the health effects of their short- or long-term use.
- Trial name
- Cinimic (NCT03700892)
- Testing
- Cinnamaldehyde e-liquid, PG/VG e-liquid
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Electronic Cigarette Use, Smoking, Cigarette
Assessing E-Cigarettes for Tobacco Harm Reduction in the Context of Lung Cancer Screening
This study investigates the feasibility, acceptability, and short-term effects of providing 4 weeks of complimentary electronic cigarettes (ECs) to 30 individuals who did not quit after smoking cessation treatment provided in the…
- Conditions
- Electronic Cigarette Use, Smoking, Cigarette, Nicotine Dependence
- Trial name
- NCT06472869
- Testing
- NJOY ACE e-cigarette
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Vaping Teens, Healthy Volunteers
Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study
The purpose of this translational bench-to-bedside study is to examine the neurobiological effects of an evidence-based technology-delivered mindfulness training (MT) program on vaping-related rsFC alterations in hippocampal…
- Trial name
- NCT06503159
- Testing
- Mindfulness-based Stress Reduction (MBSR) Program, functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Electronic Cigarette Use
Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC
The goal of this study is to conduct a pilot randomized waitlist-controlled trial to assess the feasibility, acceptability, and preliminary effects of substituting the NIDA standardized research e-cigarette (SREC) for combusted…
- Trial name
- SWITCHED (NCT05881304)
- Testing
- Standardized research e-cigarette (SREC)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vaping Behavior
Impact of E-Cigarette Prevention Messages on Adolescents
The purpose of this trial is to determine whether a vaping prevention text message program reduces susceptibility to vaping among adolescents and young adults.
- Trial name
- NCT05985538
- Testing
- Vaping prevention text messages, Wellness behaviors text messages
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Electronic Cigarette Use
Assessing Electronic Cigarette Nicotine Flux
The purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an electronic cigarette with constant…
- Trial name
- NCT04378907
- Testing
- Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
E-Cig Use
Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0
This pilot sensory experiment will examine cooling from comparable concentrations of WS-3 and menthol to determine appropriate concentrations to use in the main study.
- Trial name
- NCT05932693
- Testing
- E-liquid coolant (WS-3, 0.05%), E-liquid coolant (WS-3, 0.1%), E-liquid coolant (WS-3, 0.5%)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Yale University
Cough
Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system.
- Trial name
- NCT02203162
- Testing
- electronic cigarette exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
E-cigarette Use
Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath
This is a two-arm, cluster randomized trial designed to to evaluate the effectiveness of an e-cigarette curriculum [called the CATCH My Breath (CMB) program] in delaying the onset of e-cigarette use in middle schoolers.
- Trial name
- NCT04843501
- Testing
- CATCH My Breath (CMB) program for E-cigarette prevention among adolescents, Texas Education Agency (TEA) required tobacco prevention program
- Where
- United States
- Volunteers
- 2,059 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Vaping, Smoking
Adolescent Inpatient Tobacco and ENDS Intervention
The purpose of this study is to develop and evaluate an evidence-based intervention to assist adolescents and young adults with current vaping to quit vaping and smoking.
- Trial name
- NCT05936099
- Testing
- E-cigarette & Tobacco Use Treatment Intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Tobacco Cessation
Text Message Quit Vaping Intervention for Young Adults
This research study, conducted by Truth Initiative, will help us learn how text messaging can help young adults between 18 and 24 years of age quit vaping.
- Trial name
- NCT04251273
- Testing
- This is Quitting, Assessment only Control
- Where
- United States
- Volunteers
- 2,588 people, healthy volunteers welcome
- Sponsor
- Truth Initiative